Clinical trials: Innovative Procedures
Dysphagia
Innovative Patient-partner-guided Virtual Group Speech Pathology Intervention Model in Head and Neck Cancer
This project aims to study an innovative intervention, the eG2 Intervention, developed by speech-language pathologists at the Centre hospitalier de l'Université de Montréal to improve therapeutic adherence and prevent dysphagia…
- Trial name
- NCT05621889
- Testing
- virtual group speech therapy intervention guided by a patient partner
- Where
- Canada
- Volunteers
- 76 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Obesity, Metabolic Syndrome
The HOMBRE Trial: Comparing Two Innovative Approaches to Reduce Chronic Disease Risk Among Latino Men
The purpose of this study is to test a flexible lifestyle program designed to help Latino men make healthy lifestyle changes to lower their risk of developing diabetes and heart disease.
- Conditions
- Obesity, Metabolic Syndrome, Lifestyle Intervention, Pre Diabetes
- Trial name
- HOMBRE (NCT03092960)
- Testing
- Minimal intensity intervention, HOMBRE
- Where
- United States
- Volunteers
- 424 people
- Sponsor
- Palo Alto Medical Foundation
Glaucoma, Trabeculectomy
Innovative Tube Trabeculectomy for Advanced and Refractory Glaucoma: A Randomized Controlled Trial
This study aims to compare the efficacy and safety of a novel surgical technique, Innovative Tube Trabeculectomy (ITT), against conventional trabeculectomy in patients with advanced and refractory glaucoma.
- Conditions
- Glaucoma, Trabeculectomy, Innovative Procedures
- Trial name
- ITT-RCT (NCT07755761)
- Testing
- Innovative Tube Trabeculectomy, Conventional Trabeculectomy
- Where
- Egypt
- Volunteers
- 116 people
- Sponsor
- Benha University
Hearing Loss
INSPIRES Hearing Health Trial - INnovative Psychological Intervention to REduce Stigma in Hearing Health Trial
Background: Reminding people they are moral adaptable human beings ("self-affirming") reduces the perceived stigma associated with wearing hearing aids and increases actual hearing aid use.
- Trial name
- INSPIRES (NCT04680845)
- Testing
- Self-affirmation
- Where
- United Kingdom
- Volunteers
- 3,012 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Substance Use Disorder (SUD)
Trauma-informed Intervention to Reduce Substance Use and to Support Community Transition
The overall aim of this study is to reduce overdose risk for criminal legal system (CLS) involved women during community re-entry through the adaptation and testing of an innovative, trauma-informed, relational intervention…
- Trial name
- TRUST (NCT06651528)
- Testing
- TAU + TRUST, TAU + TRUST + Re-entry Recovery Support, Treatment as Usual (TAU)
- Where
- 4 sites in United States
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- Michele Staton
Carotid Atheroma
Carotid Plaque Characterization Using Innovative Ultrasound Techniques
Strokes are the second leading cause of disability and death worldwide (according to World Health Organization in 2019). They are ischemic in origin in 80% of cases.
- Trial name
- CARPUS (NCT06804707)
- Testing
- blood sampling, ultrasound imaging exam, High resolution MRI plaque exam
- Where
- France
- Volunteers
- 17 people
- Sponsor
- Hospices Civils de Lyon
Stress Urinary Incontinence in Women
Evaluation of Duloxetine and Innovative Pelvic Floor Muscle Training in Women With Stress Urinary Incontinence
This study will evaluate the safety, tolerability and efficacy of duloxetine and pelvic floor muscle training in women who suffer from stress urinary incontinence
- Trial name
- DULOXING (NCT04140253)
- Testing
- Pelvic floor muscle training (PFMT) with lumbopelvic stabilization
- Where
- Slovakia
- Volunteers
- 158 people
- Sponsor
- Comenius University
Cigarette Smoker, Current Every Day Smoker
Mobile Smoking Cessation Intervention in Enhancing Cancer Outreach in Low-Income Adult Smokers
This trial studies how well a mobile smoking cessation intervention works in enhancing cancer outreach in low-income adult smokers.
- Trial name
- NCT00948129
- Testing
- Laboratory Biomarker Analysis, Smoking Cessation Intervention, Telephone-Based Intervention
- Where
- United States
- Volunteers
- 626 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Health Knowledge, Attitudes, Practice, Vaccine-Preventable Diseases
Culturally Tailored HPV Psychoeducational Multimedia Intervention
Community members ages 18 - 45 years old from the El Paso, Texas, U.S.-Mexico Border Region will be recruited to compare psychoeducational multimedia interventions focused on the human papillomavirus (HPV).
- Conditions
- Health Knowledge, Attitudes, Practice, Vaccine-Preventable Diseases, Intention, Adherence, Patient
- Trial name
- NCT06098690
- Testing
- Culturally Tailored Multimedia Psychoeducational HPV Intervention, General HPV Multimedia Psychoeducational Control Group
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of Texas, El Paso
High Blood Pressure
Use of an Innovative Mobile Health Intervention to Improve Hypertension Among African-Americans
The project objective is to test the feasibility of delivering health education and self-management support to African-American patients with uncontrolled hypertension (HTN) through a culturally-tailored smartphone application…
- Trial name
- NCT04554147
- Testing
- FAITH! App-enhanced Hypertension Intervention
- Where
- 3 sites in United States
- Volunteers
- 16 people
- Sponsor
- Mayo Clinic
Opioid-Related Disorders, HIV Infections
Buprenorphine and Integrated HIV Care Evaluation
The purpose of this study is to assess the feasibility, cost and effectiveness of interventions designed to integrate buprenorphine treatment for opioid dependence into HIV primary care in ten HIV care centers in the U.S.
- Conditions
- Opioid-Related Disorders, HIV Infections, AIDS
- Trial name
- NCT00124358
- Testing
- Buprenorphine, Integrated HIV care and office-based opioid dependence treatment
- Where
- 10 sites in United States
- Volunteers
- 1,350 people
- Sponsor
- The New York Academy of Medicine
Non Communicable Diseases
The Impact of Dietary Intervention on Oxidative/antioxidant Markers and Gut Microbiota in Athletes
During intense physical exercise, there is an overproduction of reactive oxygen species, which leads to oxidative stress and reduced training and sports performance, as well as the development of chronic diseases.
- Trial name
- SportDiet (NCT06855979)
- Testing
- Food with high antioxidant potential
- Where
- Poland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medical University of Bialystok
Opioid-Related Disorders, Opioid Dependence
An Innovative Intervention for OUD Treatment
The Bridge Device (BD) is a neuromodulator medical device that has been cleared by the FDA for Opioid Use Disorder (OUD) treatment.
- Conditions
- Opioid-Related Disorders, Opioid Dependence, Opioid Addiction, Opioid Withdrawal
- Trial name
- Bridge (NCT04325659)
- Testing
- Bridge Device, Lofexidine
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Social Isolation in Older Adults, Loneliness
An Innovative App-based Intervention to Promote Social Connectedness and Well-being in Older Adults
This study evaluates the impact of a group-based intervention designed to promote social connectedness and enhance psychological well-being among older adults.
- Trial name
- VITA (NCT07443813)
- Testing
- Blended VITA intervention (hybrid app-based and in-person social engagement program)
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Padova
Prostate Cancer
Cooking Class Intervention Project for Men With Prostate Cancer and Their Partners
Prostate cancer is one of the most commonly diagnosed cancers in Canada, with 24,000 new cases estimated for 2015. Prostate cancer patients often live with uncomfortable side effects of treatment, such as a decrease in bone…
- Trial name
- NCT02954289
- Testing
- Dietary intervention
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- University of British Columbia
Hypertension Arterial, 65 Years Older
Mitigation of Health Effects in Older Adults With Hypertension by Reducing Exposure to Heat and Air Pollution
The goal of this clinical trial is to assess the effectiveness of an intervention (combination of behavioural recommendations and technical measures) in reducing personal exposure to heat and air pollution and related health…
- Trial name
- ISMED CLIM OH (NCT07606859)
- Testing
- Heat intervention, Heat and air pollution mitigation intervention
- Where
- 2 sites in Cyprus, Spain
- Volunteers
- 102 people
- Sponsor
- University of Cyprus
Overweight and Obesity
Text2bHealthy: Using Innovative Methods in Childhood Obesity Treatment
In Canada, the number of obese children and adolescents has increased tremendously. Interventions addressing diet and physical activity have been successful in the short-term.
- Trial name
- NCT01800331
- Testing
- Text2bHealthy
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- University of British Columbia
Type 2 Diabetes, PreDiabetes
Promote Health With Digital Tools Among Adults With Type 2 Diabetes/Prediabetes and/or Hypertension
The goal of this hybrid type II effectiveness-implementation trial is to evaluate whether an intersectoral, digitally enabled, family-based intervention can prevent and manage type 2 diabetes mellitus (T2DM) and hypertension…
- Conditions
- Type 2 Diabetes, PreDiabetes, Hypertension, Obesity & Overweight
- Trial name
- DigiCare4You (NCT05648383)
- Testing
- mHealth self-management intervention, Standard care
- Where
- 4 sites in Albania, Bulgaria and 2 more
- Volunteers
- 1,215 people, healthy volunteers welcome
- Sponsor
- Harokopio University
Cigarette Smoking, Current Smoker
Quit4Health Intervention in Supporting Smoking Cessation and Preventing Smoking Initiation in Young Adults
This trial studies how well Quit4Health intervention works in supporting smoking cessation and preventing smoking initiation in young adults.
- Trial name
- NCT04009590
- Testing
- Educational Intervention, Questionnaire Administration, Smoking Cessation Intervention
- Where
- United States
- Volunteers
- 579 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Nervous System Diseases, Oculomotor; Disorder
Innovative Physical Therapy Modalities in People With a Neurological Disease: Oculomotor Therapy and Adapted Yoga
Physiotherapy is a discipline which englobe not only the rehabilitation of physical pathologies but also their prevention. That is why this study pretends to upgrade this part of the physical therapy specialty while prove new…
- Conditions
- Nervous System Diseases, Oculomotor; Disorder, Physical Dependence, Physical Inactivity
- Trial name
- NeuPhysioLRG (NCT05709691)
- Testing
- Oculomotor therapy, Adapted yoga
- Where
- Spain
- Volunteers
- 128 people
- Sponsor
- University of Malaga