Clinical trials: Innovative Procedures
Autism Spectrum Disorder
Tele-rehabilitation Program: An Innovative and Sustainable Early Intervention Service for Children With Autism Spectrum Disorders
In Singapore, Autism Spectrum Disorders (ASD) is ranked number one in disease burden for children 0-14 years of age. The Child Development Unit at the National University Hospital serves 3000 children annually, of which 25-30% of…
- Trial name
- NCT05792449
- Testing
- Foundational Skills Curriculum, Foundational Skills Curriculum - Telerehabilitation
- Where
- Singapore
- Volunteers
- 200 people
- Sponsor
- National University Hospital, Singapore
Chronic Obstructive Pulmonary Disease (COPD)
Innovative Pulmonary Solutions (IPS) System for Targeted Lung Denervation
The purpose of this study is to evaluate the safety of Targeted Lung Denervation Therapy (or TLD TherapyTM) in patients suffering from COPD.
- Trial name
- IPS-I (NCT01483534)
- Testing
- TLD Therapy (IPS SystemTM)
- Where
- 3 sites in Netherlands, South Africa
- Volunteers
- 22 people
- Sponsor
- Nuvaira, Inc.
Solid Tumor, Solid Tumor, Adult
Adapting for Latinx Populations an Intervention That Involves Discussing and Sharing Patients' Health-Related Values
The purpose of this study is to translate and tailor for Latinx participants a program called Communicating with Oncology Nurses about Values from the Outset (CONVO).
- Conditions
- Solid Tumor, Solid Tumor, Adult, Solid Tumor, Unspecified, Adult
- Trial name
- NCT04942717
- Testing
- CONVO intervention
- Where
- 5 sites in United States
- Volunteers
- 234 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Transcatheter Mitral Valve Edge-to-Edge Repair System, Biodegradable Patent Foramen Ovale Closure Device
Active Surveillance and Safety/Efficacy Evaluation of Innovative Devices for Structural Heart Disease Intervention
This study aims to establish an active surveillance system to evaluate the safety and effectiveness of innovative medical devices used in the interventional treatment of structural heart disease.
- Trial name
- ASSEE-SHD (NCT07848152)
- Where
- 11 sites in China
- Volunteers
- 2,200 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Breast Cancer
Advanced MR Techniques for Breast Cancer Detection
Evaluation of advanced MRI acquisition techniques (perfusion and diffusion) to detect breast cancer. Two MR advanced sequences will be added to a standard breast MRI protocol for evaluation purpose.
- Trial name
- RAPIDIRM (NCT04020523)
- Testing
- MRI sequence
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Mental Health Issue
Providing Access To Innovative & Evidence-Based Intervention
PROACTIVE Parent is an educational program designed to improve parenting skills to more effectively manage child behavior and social and emotional needs in children with depressive symptoms.
- Trial name
- PROACTIVE (NCT04986800)
- Testing
- PROACTIVE Parent
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northwestern University
Breast Neoplasms
Smart-phone Health Coaching Intervention to Promote Maintenance of Exercise in Breast Cancer Survivors:Protocol
While physical activity (PA) appears to play an important role in disease control and the promotion of long-term health and well-being of cancer survivors, the large majority of breast cancer survivors are not physically active.
- Trial name
- iMOVE (NCT02620735)
- Testing
- Fit bit Device, Exercise Only, Connected Wellness HealthCoach Software
- Where
- Canada
- Volunteers
- 114 people
- Sponsor
- University Health Network, Toronto
Dislodged Catheter, Catheter Related Complication
An Innovative Taping Technique for Improved Intravenous (IV) Catheter Securement
This is a prospective, single-blinded, randomized study to assess the ability of taping methods used to secure intravenous (IV) catheters to resist the IV from being pulled away from the skin.
- Trial name
- NCT05948878
- Testing
- Novel Taping Method, BCH Emergency Department Taping Method, Chevron Taping Method
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Pelvic Organ Prolapse, Pelvic Organ Prolapse Vaginal Surgery
To Explore the Surgical Outcomes and Safety of an Innovative Laparoscopic Uterine Pectopexy Technique Using Inverted T-meshes for Simultaneous Apical and Anterior Vaginal Repair.
Patients referred for pelvic reconstructive surgery frequently present with combined anterior and apical vaginal wall prolapse. Previous studies found that anterior compartment involvement is the most common and serious defect…
- Conditions
- Pelvic Organ Prolapse, Pelvic Organ Prolapse Vaginal Surgery, Pectopexy, Sacrocolpopexy
- Trial name
- NCT07411898
- Testing
- Laparoscopic pectopexy, Laparoscopic sacrocolpopexy
- Where
- Taiwan
- Volunteers
- 67 people
- Sponsor
- Chung Shan Medical University
Primary Care
Physical Inactivity and Sedentary Behavior: Screening and Intervention in Ambulatory Primary Care
Physical inactivity and sedentary behaviors are among the leading modifiable risk factors for chronic diseases. In France, despite the national Sport Health strategy, awareness campaigns physical inactivity and sedentary behavior…
- Trial name
- IPSEDI (NCT06678906)
- Testing
- Intervention arm
- Where
- France
- Volunteers
- 160 people
- Sponsor
- University Hospital, Grenoble
Suture Techniques, Medical Glue
Innovative Suture Technique for Endoscopic Hernia Incision
The minimally invasive surgical technique represented by endoscopy is one of the most important inventions in the medical field of the 20th century.
- Trial name
- NCT05781932
- Testing
- Dermal barb suture combined with medical glue
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Yizhuo Lu, MD
Mobile Application-Based CBT Worksheet Collection, Paper-Based Worksheet Collection
Innovative Methods to Assess Psychotherapy Practices (imAPP)
This project compares two methods of assessing the quality of cognitive behavioral therapy (CBT) that do not involve directly observing sessions: 1) adherence checklists embedded in clinical notes, and 2) rating the quality of…
- Trial name
- NCT03479398
- Testing
- Cognitive Behavioral Therapy
- Where
- 4 sites in United States
- Volunteers
- 439 people, healthy volunteers welcome
- Sponsor
- Palo Alto Veterans Institute for Research
Autism Spectrum Disorder, Feeding Behavior
Project LEaH: Learning to Eat at Home
The investigators are trying to determine if delivery a feeding intervention program using videoconferencing technology is feasible.
- Trial name
- NCT03992118
- Testing
- Parent coaching
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
HIV, PrEP
Linking Youth to Pre-Exposure Prophylaxis (PrEP) Services
The LYPS intervention is a multi-level intervention that combines: a) structural-level delivery of PrEP and PrEP services by a community health professional (CHP) at a designated place in the community being offered by the SC…
- Conditions
- HIV, PrEP, PrEP Adherence
- Trial name
- LYPS (NCT07438041)
- Testing
- LYPS, Enhanced Standard of Care
- Where
- 4 sites in United States
- Volunteers
- 272 people, healthy volunteers welcome
- Sponsor
- Westat
Overweight and Obesity
Rapid Evaluation of Innovative Intervention Components to Maximize the Health Benefits of Behavioral Obesity Treatment Delivered Online: An Application of Multiphase Optimization Strategy
When delivered online, behavioral obesity treatments have the potential to reach large numbers of individuals with overweight/obesity and produce significant improvements in health and wellbeing.
- Trial name
- NCT04520256
- Testing
- Online Behavioral Weight Loss Program, Virtual Reality for Behavioral Weight Loss Skills Training, Tailored Interactive Video Feedback
- Where
- United States
- Volunteers
- 384 people
- Sponsor
- The Miriam Hospital
Non-communicable Diseases (NCD), Neoplams
Health for Hungary (H4H) - Longitudinal Collection of Blood Samples and Corresponding Data
The Health for Hungary (H4H) study collects blood samples and corresponding health data to investigate healthy aging and health-to-disease transitions in middle-aged and elderly participants.
- Conditions
- Non-communicable Diseases (NCD), Neoplams, Cancer, Lung Cancer (NSCLC)
- Trial name
- H4H (NCT07743021)
- Where
- 33 sites in Hungary
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Center for Molecular Fingerprinting Research Nonprofit LLC
Childhood Obesity, Sleep Problems
Evaluation of Innovative School-based Interventions on Health Outcomes Among Primary School Students During Post COVID-19 Pandemic
Objectives: (1) to evaluate the feasibility of innovative school-based interventions on health outcomes (psychological well-being, depressive symptoms, anxiety symptoms, physical activity, sleep duration, and sleep quality) among…
- Conditions
- Childhood Obesity, Sleep Problems, Physical Activity
- Trial name
- WeJoy+WeHop (NCT06766890)
- Testing
- WeJoy+WeHop
- Where
- Hong Kong
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Tobacco Use Cessation, Cigarette Smoking
Innovative Web-Based Intervention for Smoking Cessation Among College Students
Tobacco use is the leading cause of cancer death in the U.S. Because smokers who quit by age 30 have cancer death risk similar to non-smokers, promoting cessation early in life is critical. U.S.
- Trial name
- NCT01982825
- Testing
- Online intervention arm, Online control arm
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Emory University
Sickle Cell Anemia in Children
Effectiveness of Innovative Educational Methods in Empowering Children With Sickle Cell Disease
Sickle-cell disease (SCD) is a genetic disorder that affects hemoglobin, the molecule in red blood cells responsible for carrying oxygen.
- Trial name
- NCT07802210
- Testing
- video intervention, game intervention
- Where
- Iraq
- Volunteers
- 120 people
- Sponsor
- Aula Ibrahim abd alrazak
Sexual Risk, Substance Use
An Innovative HIV Prevention Intervention Using Social Networking Technology
An existing face-to-face HIV prevention intervention (The Young Men's Health Project, YMHP; R01DA20366) will be iteratively adapted and pilot-tested to target difficult to engage high-risk young men who have sex with men (YMSM)…
- Trial name
- NCT01381653
- Testing
- Behavioral: HIV prevention intervention
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hunter College of City University of New York