Clinical trials: Insect Bites
Insect Bites
Comparative Study of Two Forms of Topical Dexchlorpheniramine Maleate (Cream Versus Gel) for Insect Bites
Insect bite related symptoms (pruritus and papules) are caused by the release of histamine by mast cells in the skin. Topical anti-histaminics can be used to promote relief of these symptoms.
- Trial name
- NCT01233934
- Testing
- Dexchlorpheniramine 1% Gel, Dexchlorpheniramine 1% Cream
- Where
- Brazil
- Volunteers
- 90 people
- Sponsor
- Mantecorp Industria Quimica e Farmaceutica Ltd.
Leishmaniasis, Cutaneous Leishmaniases
A Clinical Study to Develop a Controlled Human Infection Model Using Leishmania Major-infected Sand Flies
The disease leishmaniasis mainly occurs in hot and tropical countries, affects millions of people and causes around 20,000 deaths across the world every year.
- Conditions
- Leishmaniasis, Cutaneous Leishmaniases, Insect Bites
- Trial name
- LEISHChallenge (NCT04512742)
- Testing
- biting by Phlebotomus duboscqi infected with Leishmania major
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of York
Hypersensitivity, Immediate
Clinical and Immunological Evaluation of Children With Allergies
This study will evaluate children with allergies and collect medical data and biological specimens from them periodically to learn more about the diseases and gain information that may be useful in developing new treatments.
- Trial name
- NCT00102570
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Zika, Dengue
Defining Skin Immunity of a Bite of Key Insect Vectors in Humans
Background: Mosquitoes and similar insects called sand flies carry parasites that can cause diseases. These viruses and parasites can spread quickly and be difficult to control.
- Conditions
- Zika, Dengue, Malaria, Chikungunya
- Trial name
- NCT03641339
- Testing
- One vector feeding, Four vector feeding
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Insect Bites and Stings
Ease-it Spray for the Treatment of Fire Ant Stings
The application of Ease-it Spray will alleviate pain secondary to fire ant stings more quickly than placebo.
- Trial name
- NCT00435552
- Testing
- Ease-It Spray
- Sponsor
- C.R.Darnall Army Medical Center
Sting
Cimex Lectularius or Bed Bugs : Vector of Infectious Agents and Pathogenic Role
During the last years, the investigators were the witness to the increase of a old emerging pest due to bed bugs (Cimex lectularius) in the world.
- Trial name
- NCT01089465
- Testing
- Collection of the bedbugs and dermatological follow-up of the stings
- Where
- France
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Insect Bites, Stings
Evaluation of Zapperclick Device for Relief From Mosquito Bites
Mosquito bites commonly result in redness, swelling and itching. This study will determine if a device that emits a small piezo-electrical impulse can provide relief from these symptoms.
- Trial name
- NCT00825214
- Testing
- Zapperclick, Inactivated zapperclick device
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Leishmaniasis, Cutaneous, Insect Bites
A Clinical Study to Develop an Uninfected Sand Fly Biting Protocol
The disease leishmaniasis mainly occurs in hot and tropical countries, affects millions of people and causes around 20,000 deaths across the world every year.
- Trial name
- FLYBITE (NCT03999970)
- Testing
- Sand fly bite
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of York
Spider Bite
Swiss Study on Spider Bites
About spider bites in Middle Europe, there are published only a dozen cases. The investigators suspect that they may be much more frequent than reflected by the literature analysis (but much less dangerous than thought by…
- Trial name
- SSSB (NCT01355744)
- Where
- Switzerland
- Volunteers
- 17 people
- Sponsor
- University of Zurich
Skin Pruritus, Itch
Efficacy and Safety of HA35 Gel for Ultra-Rapid Skin Pruritus Relief
This is a prospective, single-arm, open-label, pilot clinical study to evaluate the efficacy and safety of topical 10% high-concentration 35 kDa hyaluronan (HA35) gel for ultra-rapid relief of moderate-to-severe skin pruritus…
- Conditions
- Skin Pruritus, Itch, Eczema Itch, Neurodermatitis
- Trial name
- HA35-ITCH (NCT07580911)
- Testing
- 10% High-Concentration 35 kDa Hyaluronan (HA35) Topical Anti-Pruritic Gel
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Nakhia Impex LLC
Bites and Stings
Field Evaluation of Two Topically Applied Insect Repellent Products Containing IR3535 Against Mosquitos in Louisiana
To determine the efficacy and duration of protection of two topically applied insect repellent products at preventing landing by mosquitos. The study will follow the EPA Product Performance Test Guidelines1.
- Trial name
- NCT05394597
- Testing
- Repellent lotion, Repellent Wipe
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Tick Bites
Determining the Complete Protection Time of an Insect Repellent With 30% Citriodiol® Against Three Species of Ticks.
This study evaluates the length of time an insect repellent product can protect against three species of ticks. Participants will have one arm treated with the repellent, and throughout the next 10 hours, ticks will be given the…
- Trial name
- NCT03708120
- Testing
- Citrepel (Insect Repellent) EPA Reg. No. 84878-2
- Where
- United Kingdom
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- ARCTEC
Hypersensitivity, Immediate, Insect Bites and Stings
The Significance of Blood-tryptase and c-Kit Mutation in Insect Venom Immunotherapy
The investigators wish to evaluate the association between tryptase values as well as c-Kit mutation and adverse effects in the course of immunotherapy.
- Conditions
- Hypersensitivity, Immediate, Insect Bites and Stings, Mastocytosis
- Trial name
- NCT02503800
- Where
- Israel
- Volunteers
- 159 people
- Sponsor
- Meir Medical Center
Insect Bites
Non-inferiority Clinical Trial of Dexchlorpheniramine (Cream Versus Lotion) in the Relief of Insect Bite Related Symptoms
Insect bite related symptoms (pruritus and papules) are caused by the release of histamine by mast cells in the skin. Topical anti-histaminics can be used to promote relief of these symptoms.
- Trial name
- NCT00995397
- Testing
- Dexchlorpheniramine 1% lotion, Dexchlorpheniramine 1% cream
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Mantecorp Industria Quimica e Farmaceutica Ltd.
Cellulitis, Insect Bites
Point-of-Care Ultrasound Educational Initiative for Insect Bites
This pre-post study, designed to decrease unnecessary antibiotic prescribing, will use a prospective cohort of patients presenting to the Pediatric Emergency Department (PED).
- Conditions
- Cellulitis, Insect Bites, Insect Stings
- Trial name
- USED4BUGBITE (NCT03619746)
- Testing
- POCUS Educational Intervention
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- New York City Health and Hospitals Corporation