Clinical trials: Insemination
Infertility Unexplained, Infertility, Male
Impact of DNA Fragmentation in Sperm on Pregnancy Outcome After Intra-uterine Insemination in a Spontaneous Cycle
Infertility affects about 10% of all couples and is defined by a failure to achieve a clinical pregnancy within a year of regular unprotected sexual intercourse.
- Conditions
- Infertility Unexplained, Infertility, Male, DNA Damage
- Trial name
- NCT03319654
- Testing
- DNA fragmentation by TUNEL assay
- Where
- Belgium
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Oxidative Stress
Sperm Oxidative Stress and Pregnancy Success During IUI and IVF
Oxidative stress (OS) is characterized by an imbalance between the production of reactive oxygen species (ROS) and the ability of the body to eliminate them.
- Trial name
- NCT03539874
- Where
- Canada
- Volunteers
- 250 people
- Sponsor
- Fertilys
Infertility
Office Hysteroscopy and Endometrial Snip Improve Intrauterine Insemination Outcome
Endometrial injury had been studied before prior to intracytoplasmic sperm injection (ICSI) cycles , in cases of repeated implantation failure. It is found that it will improve the implantation rate.
- Trial name
- NCT01544426
- Testing
- Office hysteroscopy and endometrial snip, Office hysteroscopy
- Where
- Egypt
- Volunteers
- 332 people
- Sponsor
- Cairo University
Infertility
Intrauterine Insemination and Nursing
This study investigates the effect of virtual reality glasses use and therapeutic touch on pain, anxiety and patient satisfaction in women during intrauterine insemination procedure
- Trial name
- NCT05192330
- Testing
- Virtual Reality Glasses, Therapeutic Touch
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Infertility, Female, Reproductive Techniques, Assisted
SISTER: Sibling Oocyte Insemination With Frozen Sperm From Third Party Donors: Evaluation of Reproductive Techniques
The goal of this clinical trial is to learn whether two different methods of helping eggs and sperm join-intracytoplasmic sperm injection (ICSI) and conventional in vitro fertilization (IVF)-lead to better embryo development when…
- Conditions
- Infertility, Female, Reproductive Techniques, Assisted, Fertilization in Vitro
- Trial name
- SISTER (NCT07175571)
- Testing
- Intracytoplasmic Sperm Injection (ICSI), Conventional Insemination (IVF)
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Shady Grove Fertility Reproductive Science Center
Infertility, Male Factor
FemaSeed LOCAL Artificial Insemination Trial
Brief Summary: The objectives of the trial are to evaluate the safety and effectiveness of the FemaSeed Localized Directional Insemination for artificial insemination, now known as the FemaSeed Intratubal Insemination since FDA…
- Trial name
- LOCAL (NCT04968847)
- Testing
- FemaSeed Localized Directional Insemination
- Where
- 18 sites in United States
- Volunteers
- 314 people, healthy volunteers welcome
- Sponsor
- Femasys Inc.
Insemination
Ultrasound Guided Artificial Insemination
The purpose of this study is to ascertain whether using ultrasound guidance during intrauterine insemination (IUI) could increase pregnancy rates.
- Trial name
- UGAI (NCT00809952)
- Testing
- recombinant FSH
- Where
- Spain
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hospital de Cruces
Pregnancy, Infertility
Microsurgical Varicocelectomy Versus No Surgery in Men With a Palpable Varicocele and an Abnormal Semen Analysis
The primary research hypothesis is that microsurgical varicocelectomy will result in an increase in live birth in infertile couples where the male partner has a palpable varicocele and an abnormal semen analysis in comparison to…
- Trial name
- VIA (NCT00767338)
- Testing
- Timed intercourse, Microsurgical varicocelectomy, Intrauterine insemination
- Where
- 9 sites in United States
- Volunteers
- 3 people
- Sponsor
- Yale University
Insemination, Artificial
Impact of Aluminum on Sperm DNA Quality
Between 1950 and 2013, aluminum production was multiplied by thirty in the world. Today, men's exposure to aluminum, including food products, cosmetics, air and water contamination, and a number of drugs (vaccine, gastric…
- Trial name
- NCT03549533
- Testing
- samples of sperm
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Unexplained Pregnancy Loss
Effect of Intrauterine Insemination on Subsequent Pregnancy Outcomes in Couples With Unexplained Pregnancy Loss: A Multicenter, Open-label, Randomized Controlled Trial
Unexplained pregnancy loss remains a major reproductive challenge, and effective management strategies for affected couples are limited.
- Trial name
- NCT07759609
- Testing
- Intrauterine Insemination (IUI)
- Where
- 3 sites in China
- Volunteers
- 558 people
- Sponsor
- Lanzhou University Second Hospital
Male Factor Infertility
Double vs Single Intrauterine Insemination in Male Factor Infertility
The aim of the study is to compare the pregnancy outcomes of single vs double intrauterine insemination (IUI) in couples with male factor infertility.
- Trial name
- NCT05885516
- Testing
- intrauterine insemination
- Where
- Turkey (Türkiye)
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- Umraniye Education and Research Hospital
Infertility
Effect of Cervical Occlusion During Intrauterine Insemination (IUI)
Study Hypothesis: There is a difference in pregnancy rates between intrauterine insemination (IUI) in cycles performed with cervical occlusion by a balloon catheter designed for sonohysterograms as compared to those performed…
- Trial name
- NCT00951171
- Testing
- Intrauterine Insemination, IUI with the standard inseminator
- Where
- United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Compare Pregnancy Rates Between FSH Stimulation and FSH and, GnRH Antagonist
Single Injection of Ganirelix in Gonadotropin Intrauterine Insemination (IUI) Cycles
Ovulation induction (OI) using gonadotropins is one of the most widely prescribed treatments of infertility. One common problem encountered while attempting OI using gonadotropins is premature ovulation.
- Trial name
- NCT01286051
- Testing
- Follistim administration, Follistim plus Ganirelix
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Houston Fertility Institute
Oxidative Stress
The Effect of the Sexual Abstinence Period on the Production of Reactive Oxygen Species in Patients Who Planned to Take Part in Intrauterine Insemination
To determine the ideal sexual abstinence time for producing high quality sperm
- Trial name
- NCT02401997
- Testing
- sexual abstinence
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Gazi University
Infertility, Intrauterine Insemination
Neuman Systems Model and Infertility Stress
In this study, it is aimed to determine the effect of Neuman Systems Model based nursing approach on stress an coping with stress for women received intrauterine insemination (IUI) treatment.
- Trial name
- NCT04785872
- Testing
- Education
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Ankara University
Infertility
Pre-washing the Catheter With a Culture Medium Before Intrauterine Insemination
The aim of the study to evaluate the possible effect of washing the insemination catheters before intrauterine insemination on the pregnancy outcomes.
- Trial name
- NCT04736459
- Testing
- Pre-washed catheter vs. Unwashed catheter in the intrauterine insemination
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Infertility
Luteal Support and Intrauterine Insemination (IUI) With Clomiphene Citrate
The purpose of this study is to assess the effect of luteal phase supplement (LPS) on pregnancy rate in IUI cycles stimulated with clomiphene citrate.
- Trial name
- NCT01046708
- Testing
- micronized progesterone
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Pregnancy
Timing of Intrauterine Insemination (IUI) 24 or 48 Hours After Spontaneous Luteinizing Hormone (LH) Peak
The aim of the present study is to prospectively evaluate whether performing an intra-uterine insemination 24 hours after the spontaneous LH peak may result in significantly higher ongoing pregnancy rates compared to 48 hours.
- Trial name
- NCT01622023
- Testing
- intra-uterine insemination
- Where
- Belgium
- Volunteers
- 435 people
- Sponsor
- Universitair Ziekenhuis Brussel
Infertility
Tolerability and Satisfaction With Evie
The purpose of this study is to determine patient satisfaction and tolerability of the Evie® slow-release insemination device for US population.
- Trial name
- NCT01969812
- Testing
- Evie Slow-release Insemination Device, Traditional Intrauterine Insemination
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Poor Ovarian Response
How Dose Coenzyme Q10 Supplementation During Infertility Treatment Effects Pregnancy Outcome
As women age the ovarian response and pregnancy rate are reduced while the rate of chromosomal abnormalities in the embryos is increased.
- Trial name
- CoQ10 (NCT00878124)
- Testing
- Coenzyme Q10 co treatment
- Where
- 2 sites in Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Toronto