Clinical trials: Insemination
Infertilities
Comparison of the Efficiency of Intra-uterine Insemination and in Vitro Fertilization in Women Over 37 Years
As age increases the chances for a woman to become pregnant decrease as well spontaneously as through assisted reproductive technologies (ART).
- Trial name
- AMPAGE (NCT02001870)
- Testing
- In Vitro Fecundation (IVF), Intra Uterine Insemination (IUI)
- Where
- 12 sites in France
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Infertility
Progesterone Supplementation After Letrozole-stimulated Insemination
This trial aims to investigate whether luteal phase support improves the chance of pregnancy in women undergoing intrauterine insemination (IUI) following ovarian stimulation with letrozole.
- Trial name
- LIFT (NCT07508657)
- Testing
- Progesterone
- Where
- 4 sites in Denmark
- Volunteers
- 690 people
- Sponsor
- Kirstine Kirkegaard
Infertility, Intrauterine Insemination (IUI)
Interest of Sperm Insemination at 42 Hours Post hCG Compared to 36h in Intrauterine Insemination
Intrauterine insemination (IUI) is a common therapeutic option to treate infertility. Typically performed 36 hours post-hCG injection to trigger ovulation.
- Trial name
- SYNcIU (NCT06804538)
- Testing
- Insemination between 42 and 43 hours post hCG, Insemination between 36 and 37 hours post hCG
- Where
- 4 sites in France
- Volunteers
- 692 people
- Sponsor
- University Hospital, Toulouse
Infertility, Female, Anti-Mullerian Hormone Deficiency
Pregnancy Prediction Using Anti-Müllerian Hormone in Intrauterine Insemination Cycles
The goal of this study is to compare the cumulative pregnancy rates after 4 artificial inseminations with donor (IAD) in non-sterile women with plasma AMH levels > and < 1.1 ng/mL.
- Trial name
- NCT06263192
- Testing
- Intrauterine insemination
- Where
- Spain
- Volunteers
- 342 people
- Sponsor
- Jose Antonio Moreno
Infertility, Insemination
Using a Fixed Dosage of Follitropin Delta for Ovarian Stimulation for Intrauterine Insemination: Rekovelle for Intrauterine Successful Experience (RISE)
The aim of this study is to evaluate the use of a fixed dose of 3.66 mcg of follitropin delta (Rekovelle) on ovarian response during ovarian stimulation for intrauterine insemination (IUI).
- Trial name
- RISE (NCT07153367)
- Testing
- REKOVELLE (Follitropin Delta)
- Where
- 5 sites in France
- Volunteers
- 80 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Infertility Assisted Reproductive Technology, Infertility, Female
The Effect of Stress Ball Used During Intra Uterine Insemination on Pain, Anxiety, Comfort and Physiological Parameters
This study aimed to determine the effects of holding the patient's hand and using a stress ball during the Intrauterine Insemination procedure on pain, anxiety, comfort, and physiological parameters.
- Trial name
- NCT06759337
- Testing
- Stress Ball Group, Hand-Holding Group
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- TC Erciyes University
Infertility, Infertility Secondary
Sperm Preparation Prior to Intrauterine Insemination Study
This is a randomized controlled trial comparing density gradient centrifugation and microfluidic sperm sorting in patients undergoing intrauterine insemination to evaluate cumulative pregnancy outcomes.
- Conditions
- Infertility, Infertility Secondary, Infertility Unexplained, Anovulation
- Trial name
- PIoUS (NCT05693220)
- Testing
- Zymot Multi sperm separation device, Density gradient centrifugation
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- University of California, San Francisco
Unexplained Infertility, Mild Male Factor
Luteal Phase Support With Progesterone Versus Estrogen and Progesterone on Pregnancy Rates
This is a single center, 3 arms, prospective randomized controlled open study to determine the impact of luteal phase support on pregnancy rates in ovarian stimulation and IUI cycles with recombinant FSH in patients with…
- Trial name
- NCT01237535
- Testing
- Luteal support with progesterone only, Luteal support with estrogen + progesterone, Insemination without luteal support
- Where
- Israel
- Volunteers
- 400 people
- Sponsor
- Rabin Medical Center
Infertility, Unexplained Infertility
Uterine Scratching in Intra-Uterine Insemination
This study will evaluate the potential benefits of uterine injury during the follicular phase of an intra-uterine insemination cycle on the rate of ongoing pregnancy during the first trimester ultrasound.
- Trial name
- NCT03828786
- Testing
- Endometrial scratching
- Where
- Canada
- Volunteers
- 394 people, healthy volunteers welcome
- Sponsor
- Clinique Ovo
Sterility
Comparative Assessment of the Clinical Utility of Ovarian Stimulation With Menotropin Versus Menotropin Plus GnRH Antagonist
To assess the effectiveness of protocols of ovarian hyperstimulation combining urinary gonadotrophins + GnRH antagonist vs urinary gonadotrophins, to achieve clinical pregnancy in females undergoing intrauterine insemination.
- Trial name
- PROMENIA (NCT01331733)
- Testing
- hMG-HP, hMG + GnRH antagonist
- Where
- 7 sites in Spain
- Volunteers
- 131 people
- Sponsor
- Ferring Pharmaceuticals
Infertility, Male
Stress in Couples Undergoing Assisted Reproduction Technology With Donor Sperm and Its Impact on Pregnancy Outcomes
Donor sperm provides a viable option for patients with significant male factor infertility. However, since the source of sperm is not from the male partner, the psychological burden of these couples is more pronounced and complex…
- Trial name
- NCT04924309
- Testing
- Exposure: donor sperm
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Women's Hospital School Of Medicine Zhejiang University
Infertility
Individual Versus Standard Follicle Stimulating Hormone Dose for Controlled Ovarian Stimulation and Insemination
The purpose of this study is to test if recombinant follicle stimulating hormone (rFSH) given in individual doses, according to a nomogram we have constructed based on our results from a previous study, results in more patients…
- Trial name
- NCT00374634
- Testing
- rFSH drug dose, "Standard" rFSH dose
- Where
- Denmark
- Volunteers
- 234 people
- Sponsor
- Nina la Cour Freiesleben
Infertility, Female
Luteal Phase Support in Insemination Cycles
This study is a prospective randomized trial with 242 IUI cycles. Patients are randomized in two groups including 121 cycles in each group. A total of 255 cycles in 167 patients are finally recruited.
- Trial name
- NCT03115307
- Testing
- Triptorelin
- Where
- Finland
- Volunteers
- 167 people
- Sponsor
- Tampere University Hospital
Infertility
36 Versus 42 Hour Time Interval From Ovulation to Intrauterine Insemination
The purpose of this study is to prove that a higher clinical pregnancy rate can be achieved with a 42 to 44 hour time interval between ovulation trigger and intrauterine insemination than a 36 to 38 hour time interval in…
- Trial name
- NCT02210611
- Testing
- Intrauterine Insemination 36 hours, Intrauterine Insemination 42 hours
- Where
- Israel
- Volunteers
- 71 people
- Sponsor
- HaEmek Medical Center, Israel
Infertility, Pregnancy
The Effect of Pre-washing the Insemination Catheter on Pregnancy Outcome
The investigators hypothesize that washing the insemination catheter prior to performing the IUI (intrauterine insemination) will improve the pregnancy outcome in IUI cycles when compared to controls (without pre-washing the…
- Trial name
- NCT02445092
- Testing
- washing the insemination catheter with sperm washing media
- Where
- Canada
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Fertility Disorders, Fertility Issues
Menstrual Phase Endometrial Scratch in IUI Cycles
Patients undergoing treatment with intrauterine insemination (IUI) will be randomized to receive an endometrial scratch or sham procedure during the menstrual phase of the treatment cycle.
- Trial name
- NCT04641598
- Testing
- Endometrial Scratch
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Carilion Clinic
Infertility, Male Infertility
The Efficiency of a New Sperm-Wash Device for Intrauterine Insemination in Couples With Infertility
This study evaluates the effectiveness of a novel sperm-wash device designed to improve outcomes in intrauterine insemination (IUI) for couples with infertility.
- Trial name
- IUI (NCT06956287)
- Testing
- LensHooke CA0, Density Gradient Centrifugation (DGC)
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Chung Shan Medical University
Infertility, Spermatozoa
Ejaculatory Abstinence in IUI Cycles
Intrauterine insemination (IUI) combined with ovarian stimulation, has been an extensively used procedure for the treatment of patients with unexplained infertility.
- Conditions
- Infertility, Spermatozoa, Reproductive Disorder
- Trial name
- NCT04361292
- Testing
- INTRAUTERINE INSEMINATION
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Unexplained Infertility
Dual FSH/HCG Trigger in Letrozole Stimulated Intrauterine Insemination Cycles in Women With Unexplained Infertility
The objective of this study was to evaluate the outcome of follicle stimulating hormone (FSH) co-administration with human chorionic gonadotrophins trigger for women with unexplained infertility (UEI) and assigned for letrozole…
- Trial name
- NCT02739516
- Testing
- Human chorionic gonadotropin, FSH co-trigger, Letrozole
- Volunteers
- 108 people
- Sponsor
- Benha University
Infertility
IUI Schedule in Cases of High Progesterone
Intrauterine insemination (IUI) combined with ovarian stimulation protocols has become one of the first alternative treatment against infertility, although results in gestational terms are highly variable, ranging between 10% and…
- Trial name
- IAD-P4 (NCT02447588)
- Testing
- IAD at 36 hours, IAD at 24 hours
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- IVI Madrid