Clinical trials: Insomnia
Insomnia
Registry to Collect Information on Pregnancy, Neonatal, and Infant Outcomes in Pregnant Women Exposed to QUVIVIQ®
This study will investigate pregnancy, neonatal, and infant outcomes in women exposed to QUVIVIQ during pregnancy compared to women unexposed to QUVIVIQ during pregnancy.
- Trial name
- NCT06498128
- Testing
- Daridorexant, Non-orexin receptor antagonist medications for insomnia, No insomnia medication
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Idorsia Pharmaceuticals Ltd.
Insomnia Chronic, Hypnotics and Sedatives
Physical Activity Interventions for Sleep Improvement and Sedative-Hypnotic Reduction in Middle-Aged and Older Adults: Investigating the Role of Sarcopenia
Background: The prevalence of sedative-hypnotic use among middle-aged and older adults in Taiwan has continued to rise, highlighting the need to better understand the underlying factors contributing to sleep disturbances and…
- Conditions
- Insomnia Chronic, Hypnotics and Sedatives, Physical Activities
- Trial name
- NCT07896603
- Testing
- resistance training, Relaxation training
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Chang Gung Memorial Hospital
Chronic Insomnia, Chronic Pain
Lemborexant vs Clonidine vs Sedatives to Treat Insomnia in Chronic Pain Patients
Prospective observational crossover study of 250 adults undergoing chronic pain management. For insomnia treatment, patients alternate their usual prescribed sedative versus Lemborexant or Clonidine; on alternate nights.
- Conditions
- Chronic Insomnia, Chronic Pain, Restless Leg Syndrome (RLS), Substance Abuse
- Trial name
- NCT05618002
- Testing
- Lemborexant
- Where
- Canada
- Volunteers
- 250 people
- Sponsor
- Salem Anaesthesia Pain Clinic
Cancer Survivorship, Insomnia
Innovating CBT-I for Cancer Survivors: An Optimization Trial
The overall goal of this project is to conduct a factorial, randomized controlled trial to optimize synchronous, virtual delivery of CBT-I for cancer survivors.
- Trial name
- NCT06181643
- Testing
- Survivorship Sleep Program with Individual Delivery + No Booster Sessions, Survivorship Sleep Program with Group Delivery + No Booster Sessions, Survivorship Sleep Program with Individual Delivery + 3 Booster Sessions
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Massachusetts General Hospital
Insomnia
AI-Driven Digital Therapeutic for Insomnia: Development and Clinical Validation
Insomnia is a prevalent global health problem, with approximately one in five Taiwanese adults chronically affected. Prolonged use of sedative-hypnotic medications carries risks of adverse effects, dependence, and unnecessary…
- Trial name
- BBTI app (NCT07880561)
- Testing
- Digital BBTI-Based Sleep Management, AI-Assisted Sleep Education and Personalized Guidance
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Taipei Medical University
Insomnia
Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) for Insomnia During the Withdrawal-Rehabilitation Period of Methamphetamine Use Disorder
The Department of Acupuncture-Moxibustion, the First Affiliated Hospital of Zhejiang Chinese Medical University is conducting a clinical research project entitled "Randomized Controlled Clinical Trial of Transcutaneous Auricular…
- Trial name
- NCT07899957
- Testing
- taVNS
- Volunteers
- 96 people
- Sponsor
- The First Affiliated Hospital of Zhejiang Chinese Medical University
Back Pain, Insomnia
Trial on the Effect of Optically Modified Fiber Mattress Covers on Sleep Disturbances in Patients With Chronic Back Pain
Sleep quantity and quality can be influenced by the type of mattress used. This study is being done to see if a mattress cover with optically active particles can help back pain and improve sleep quality.
- Trial name
- NCT00969540
- Testing
- Active Mattress Cover
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of California, Irvine
Chronic Insomnia During Perimenopause and Menopause
Clinical Efficacy of Thumbtack Needle for Chronic Insomnia in Perimenopausal and Menopausal Women
A multicenter, randomized, controlled, blinded clinical trial was conducted to evaluate the effects of thumbtack needle on sleep in patients with chronic insomnia during perimenopause and menopause.
- Trial name
- NCT07229976
- Testing
- thumbtack needle
- Where
- 8 sites in China
- Volunteers
- 198 people
- Sponsor
- Huazhong University of Science and Technology
CVA (Cerebrovascular Accident), Ictus
Music Therapy in Post-Stroke Patients: A Clinical Trial
The goal of this clinical trial is to learn if music therapy works to optimizate sleep quality in patients who have suffered a stroke.
- Conditions
- CVA (Cerebrovascular Accident), Ictus, Stroke Acute, Insomnia
- Trial name
- NCT07899034
- Testing
- Music therapy
- Where
- Spain
- Volunteers
- 84 people
- Sponsor
- Universidad de Granada
Insomnia
Assessing the Feasibility of Web-based Insomnia Treatment Among Prostate Cancer Survivors
This pilot study will recruit Black/African American prostate cancer survivors into a clinical trial and will randomize each person to 1 of 2 possible treatments - an internet-based treatment for insomnia called Sleep Healthy…
- Trial name
- SIESTA-P (NCT07128927)
- Testing
- Sleep Healthy Using the Internet (SHUTi), Patient education
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Georgetown University
Cancer, Insomnia
Evolution of Insomnia During the First Year in Patients Newly Diagnosed With Cancer
The diagnosis of cancer can be a major trigger for new sleep problems, especially insomnia, in people who did not have sleep issues before.
- Conditions
- Cancer, Insomnia, Pain, Depression Anxiety Disorder
- Trial name
- INDICA (NCT07280416)
- Where
- France
- Volunteers
- 260 people
- Sponsor
- Centre Hospitalier Emile Roux
Chronic Insomnia Disorder
Online Tai Chi Versus Digital CBT-I for Chronic Insomnia
This multicenter randomized controlled trial will compare online Tai Chi (OTC) with digital cognitive behavioral therapy for insomnia (dCBT-I) in adults with chronic insomnia disorder.
- Trial name
- NCT07853651
- Testing
- Online Tai Chi, Digital Cognitive Behavioral Therapy for Insomnia
- Where
- China
- Volunteers
- 172 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Chronic Insomnia
Shiwei Anshen Granules for Chronic Insomnia
This is a multi-center, randomized, controlled clinical study inlcuding 240 subjects with chronic insomnia. The purpose of this study is to evaluate the efficacy and safety of Shiwei Anshen Granules (an Chinese herbal…
- Trial name
- Shiwei-Anshen (NCT07895329)
- Testing
- Shiwei Anshen granules
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Dongzhimen Hospital, Beijing
Insomnia, HIV Infections
Telenursing-Based Sleep Coaching for Adults Living With HIV With Insomnia Symptoms
Insomnia is common among people living with HIV and is linked to fatigue and lower quality of life. Cognitive behavioural therapy for insomnia (CBT-I) is the recommended first-line treatment, but access is limited in Indonesia.
- Trial name
- NCT07892534
- Testing
- Telenursing-based sleep coaching
- Where
- Indonesia
- Volunteers
- 50 people
- Sponsor
- Universitas Indonesia
Chronic Insomnia
Impact of Insomnia Treatment on Brain Responses During Resting-state and Cognitive Tasks
Individuals with chronic insomnia have persistent difficulty falling and staying asleep, as well as complaints of altered daytime functioning that may be associated with cognitive impairments.
- Trial name
- NCT04024787
- Testing
- Cognitive-Behavioural therapy for insomnia (CBT-I)
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Concordia University, Montreal
Insomnia
Efficacy of Digital Cognitive Behavioral Therapy for Insomnia (CBT-I)
Insomnia is a common sleep problem, which affects 9.4-38.2% of youths worldwide. Youth insomnia is linked to mental health problems, leading to substantial health and economic burden.
- Trial name
- NCT06593262
- Testing
- app-based digital cognitive behavioral therapy for insomnia with AI chatbot, app-based digital cognitive behavioral therapy for insomnia without AI chatbot
- Where
- Hong Kong
- Volunteers
- 168 people
- Sponsor
- Chinese University of Hong Kong
Insomnia, Depression - Major Depressive Disorder
Enhancing Operational Readiness With Digital Self-Managed Cognitive Behavioral Therapy for Insomnia (CBTI)
The goal of this pilot clinical trial is to evaluate the effectiveness and delivery method of a CBTI self-managed digital mobile application in service members. The main questions it aims to answer are: RQ1.
- Conditions
- Insomnia, Depression - Major Depressive Disorder, PTSD
- Trial name
- NCT07335276
- Testing
- Cognitive Behavioral Therapy for Insomnia
- Volunteers
- 144 people
- Sponsor
- Madigan Army Medical Center
Insomnia
Brain and Heart Rhythm Responses to a Breathing-Linked Sound Application (BELL-001) in Adults With Insomnia Symptoms
The purpose of this study was to describe how brain activity and heart rhythm respond to BELL-001, a smartphone application that plays sounds linked to the user's own breathing, compared with a sham application that looks the…
- Trial name
- NCT07872007
- Testing
- BELL-001 Digital Therapeutic
- Where
- South Korea
- Volunteers
- 72 people
- Sponsor
- BELL Therapeutics Inc.
Chronic Insomnia, Cancer-related Problem/Condition
The Association Between CBT-I Dose, Sleep Duration, and Fatigue in Breast Cancer Patients
Cancer-related fatigue (CRF) and insomnia are prevalent among cancer patients and have been linked to de-creases in quality of life and poorer overall survivorship.
- Conditions
- Chronic Insomnia, Cancer-related Problem/Condition, Cancer-Related Syndrome
- Trial name
- NCT05226078
- Testing
- Cognitive Behavioral Therapy for Insomnia
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Insomnia Disorder, Mild Traumatic Brain Injury
Sleep MAPP in the Polytrauma/TBI System of Care
This pilot implementation trial will evaluate the Sleep Disorder Management Assistance for Providers and Patients (Sleep MAPP) Care Pathway in one Veterans Health Administration Polytrauma/TBI System of Care clinic.
- Trial name
- Sleep MAPP (NCT07886398)
- Testing
- Sleep MAPP Care Pathway
- Where
- 2 sites in United States
- Volunteers
- 900 people
- Sponsor
- VA Office of Research and Development