Clinical trials: Insomnia, Primary
Primary Insomnia
Acupuncture for the Treatment of Insomnia
Insomnia is a common and disabling condition associated with psychiatric and medical comorbidities and often persists despite currently available treatments.
- Trial name
- NCT00855140
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- University of Pittsburgh
Insomnia, Major Depression
Cortical GABA Concentrations in Insomnia
Disturbances in the amino acid neurotransmitter (AANt), gamma-amino butyric acid (GABA) function are hypothesized to contribute to the neurobiology of Major Depressive Disorder (MDD) and insomnia.
- Trial name
- NCT00765752
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Yale University
Insomnia Chronic
Treatment of Insomnia in Primary Care Study
The goal of this clinical trial is to learn about insomnia treatment among primary care patients with chronic insomnia. The main question it aims to answer is: Does Sleep School (a therapy for insomnia) work well to decrease harm…
- Trial name
- TIP (NCT06149273)
- Testing
- Sleep School, Treatment as usual
- Where
- Finland
- Volunteers
- 250 people
- Sponsor
- University of Turku
Sleep Initiation and Maintenance Disorders
Efficacy of Head-point Acupuncture on Insomnia
The investigators will conduct a single-center case series study. A total of 40 participants with insomnia will be enrolled. The aim of the study is to assess the therapeutic effect of head-point acupuncture for the treatment of…
- Trial name
- NCT04255901
- Volunteers
- 40 people
- Sponsor
- Chang Gung Memorial Hospital
Primary Insomnia
A Prospective Open-Label Extension Study of Gaboxadol in Primary Insomnia
To evaluate the safety and tolerability of gaboxadol in primary insomnia
- Trial name
- NCT00209950
- Testing
- Gaboxadol
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- H. Lundbeck A/S
Primary Insomnia
Adult Polysomnography Primary Insomnia Cross Over Study (0928-049)(TERMINATED)
The purpose of this study is determine whether this drug will improve your insomnia in terms of decreasing your time to fall asleep and allowing you to stay asleep longer.
- Trial name
- NCT00420810
- Testing
- MK0928 / Duration of Treatment : 8 Weeks
- Volunteers
- 138 people
- Sponsor
- H. Lundbeck A/S
Insomnia, Primary Insomnia
Long Term Treatment With Zolpidem: Nightly and Intermittent Dosing
We want to assess whether "how and when" one takes sleep medication results in similar or different outcomes with respect to symptom relief.
- Conditions
- Insomnia, Primary Insomnia, Psychophysiologic Insomnia
- Trial name
- NCT00156533
- Testing
- Zolpidem, Sugar Pill
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Rochester
Migraine Headache, Sleep
Light Exposure, Migraine Outcomes, and Sleep Quality
The purpose of this study is to examine the relationship between daily light exposure patterns, sleep quality, and migraine characteristics in adults with migraine, with and without photophobia, across an 8-week study period.
- Conditions
- Migraine Headache, Sleep, Photophobia
- Trial name
- NCT07476053
- Testing
- Ambient Lighting Condition
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Arizona State University
Primary Hypertension
The Effect of Lavender Inhalation on Anxiety, Sleep, and Blood Pressure
This study aims to determine the effects of lavender oil inhalation on anxiety, sleep quality, and blood pressure in patients with primary hypertension. The study is designed as a double-blind randomized controlled trial.
- Trial name
- NCT07192783
- Testing
- Lavender
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Ardahan University
Tension-Type Headache, Sleep Disturbance
Tension-type Headache and Its Association
To estimate the prevalence of tension-type headache among adults attending the outpatient clinics at Assiut University Hospitals, and to assess its association with smartphone use, sleep quality, and quality of life.
- Conditions
- Tension-Type Headache, Sleep Disturbance, Smartphone Addiction, Quality of Life
- Trial name
- NCT07779655
- Volunteers
- 199 people
- Sponsor
- Assiut University
Insomnia
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Neu-P11 in Subjects With Primary Insomnia
The primary objective of the study is to evaluate the safety and tolerability of Neu-P11, following the administration of multiple ascending oral doses (2, 5, 20, 50 mg or matching placebo) given nightly over 2 periods of 5 days…
- Trial name
- NCT01114126
- Testing
- Neu-P11
- Where
- France
- Volunteers
- 24 people
- Sponsor
- Neurim Pharmaceuticals Ltd.
Insomnia, Suicidal Ideation
RCT of Brief CBT-I in Primary Care Veterans With Suicidal Thoughts
There is a strong association between insomnia and suicidal thoughts and behaviors. Insomnia also frequently co-occurs with other common conditions associated with suicide such as depression and posttraumatic stress disorder.
- Trial name
- NCT03603717
- Testing
- Cognitive Behavioral Therapy for Insomnia, Sleep Hygiene
- Where
- 3 sites in United States
- Volunteers
- 283 people
- Sponsor
- VA Office of Research and Development
Insomnia
Effects of Insomnia on Simulated Driving (MK-0000-183-00)
This is a double-blind, parallel design study in elderly primary insomnia patients and demographically matched controls. The objectives if this study are primarily: 1.
- Trial name
- NCT01209728
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Insomnia
Intranasal Dexmedetomidine and Zolpidem for Treatment of Primary Insomnia
Insomnia is a significant public health burden, increasing work absenteeism and health care costs in a large proportion of the population. It causes altered cognition, emotional disturbances, and reduced quality of life.
- Trial name
- NCT05615727
- Testing
- Dexmedetomidine, Zolpidem
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Arthritis, Asthma
Integrating Behavioral Health and Primary Care for Comorbid Behavioral and Medical Problems
Behavioral problems are part of many of the chronic diseases that cause the majority of illness, disability and death. Tobacco, diet, physical inactivity, alcohol, drug abuse, failure to take treatment, sleep problems, anxiety…
- Conditions
- Arthritis, Asthma, Chronic Obstructive Lung Disease, Diabetes
- Trial name
- IBHPC (NCT02868983)
- Testing
- Integration
- Where
- United States
- Volunteers
- 4,025 people
- Sponsor
- University of Vermont
Chronic Insomnia Disorder
Modified Suanzaoren Decoction Versus Eszopiclone for the Treatment of Chronic Insomnia Disorder
The purpose of this study is to observe the cognitive function and clinical efficacy of modified Suanzaoren decoction and eszopiclone in the treatment of chronic insomnia disorder patients, and to investigate the possible neural…
- Trial name
- NCT06452953
- Testing
- suanzaoren decoction, Eszopiclone 1 mg
- Where
- China
- Volunteers
- 85 people
- Sponsor
- Central South University
Primary Insomnia
Almorexant (ACT 078573) in Adult Subjects With Chronic Primary Insomnia
A polysomnography study to evaluate the effect, safety and tolerability of oral administration of almorexant (ACT 078573) in adult subjects with primary insomnia.
- Trial name
- RESTORA 1 (NCT00608985)
- Testing
- almorexant, zolpidem
- Where
- 91 sites in Australia, Austria and 18 more
- Volunteers
- 709 people
- Sponsor
- Midnight Pharma, LLC
Primary Insomnia
Comparison of Two Temperatures to Treat Insomnia
Insomnia patients demonstrate subjective and physiological hyperarousal. The Cereve Sleep System has been proposed as a clinical treatment to reverse this hyperarousal in insomnia patients.
- Trial name
- NCT01790256
- Testing
- Cereve Sleep System at 30 degrees C, Cereve Sleep System at 14-16 degrees C
- Where
- 9 sites in United States
- Volunteers
- 144 people
- Sponsor
- Cereve, Inc.
Insomnia
A Long Term Safety Study of Suvorexant in Participants With Primary Insomnia (MK-4305-009 AM3)
This study will establish the safety and tolerability of suvorexant (MK-4305) when administered for up to 14 months. Participants will be randomized to receive suvorexant or placebo for a 12-month double-blind (DB) Treatment…
- Trial name
- NCT01021813
- Testing
- Suvorexant
- Volunteers
- 781 people
- Sponsor
- Merck Sharp & Dohme LLC
Primary Dysmenorrhea, Dysmenorrhea
Spinal Manipulation For Menstrual Symptoms and Sleep in Individuals With Primary Dysmenorrhea
The goal of this observational study is to evaluate if spinal manipulation (SM) combined with connective tissue massage (CTM) improves pain, menstrual symptoms, depression levels, and sleep quality in women with primary…
- Trial name
- NCT06673537
- Testing
- Connective Tissue Massage (CTM), Spinal Manipulation
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Istanbul University - Cerrahpasa