Clinical trials: Insomnia
Sleep Initiation and Maintenance Disorders, Insomnia
Effects Of GW679769 On Sleep Onset And Maintenance And Next Day Functioning In Subjects With Primary Insomnia
This study is designed to find the optimal (best) doses of GW679769 that could be given daily to promote sleep onset and maintain sleep during the night without significant next-day thinking impairment and drowsiness in subjects…
- Trial name
- NCT00280423
- Testing
- GW679769
- Where
- 71 sites in United States, Canada
- Volunteers
- 342 people
- Sponsor
- GlaxoSmithKline
Chronic Insomnia
Long-Term Efficacy and Safety of Ramelteon in Adults With Chronic Insomnia.
The purpose of this study to determine the long-term efficacy and safety of ramelteon, once daily (QD).
- Trial name
- NCT00247390
- Testing
- Ramelteon
- Where
- 48 sites in United States, Australia and 7 more
- Volunteers
- 451 people
- Sponsor
- Takeda
Insomnia, Sleep
Online Insomnia Treatment Program
The purpose of this study is to investigate improvements in sleep by comparing two 6-week digital programs, either online or app-based, that deliver Cognitive Behavioral Therapy for Insomnia (CBT-I), the "gold standard" treatment…
- Conditions
- Insomnia, Sleep, Sleep Disturbance, Sleep Disorder
- Trial name
- NCT05778812
- Testing
- Full Sleep, Path to Better Sleep
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Koko Home, Inc.
Chronic Insomnia
Ramelteon in Adults With Chronic Insomnia
The purpose of this study is to determine the safety and efficacy of Ramelteon, once daily (QD), in adult subjects with chronic insomnia.
- Trial name
- NCT00671567
- Testing
- Ramelteon
- Where
- 70 sites in United States
- Volunteers
- 848 people
- Sponsor
- Takeda
Insomnia, Sleep
Vestibular Nerve Stimulation to Improve Sleep
A randomized, double blind sham controlled clinical trial to evaluate the efficacy of vestibular nerve stimulation (VeNS) compared to a sham control a as a means of improving sleep as measured by ISI scores and EEG recordings The…
- Conditions
- Insomnia, Sleep, Sleep Disorders, Circadian Rhythm
- Trial name
- NCT04219566
- Testing
- VeNS
- Where
- India
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Neurovalens Ltd.
Depression, Anxiety
Evaluating Neuromodulation Technologies in Early Recovery
The study is an open-label comparative effectiveness clinical trial evaluating the impact of three neuromodulation treatment devices to improve the mental health and sobriety status of recovering substance abuse patients.
- Conditions
- Depression, Anxiety, Insomnia
- Trial name
- NCT01993277
- Testing
- Nexalin Brain Stimulator, Fischer Wallace Stimulator, David Delight Stimulator
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Behavioral Health of the Palm Beaches
Skin Ageing, Healthy Ageing
Effects of a Multi-Targeted Oral Supplement on Skin, Hair, Sleep, Energy, Cognition, Libido and Epigenetic Biological Clock Age
This study evaluated the effects of a daily oral supplement regimen (Advanced ID Brain, Heart and Eye Omega Gel Capsules taken with Advanced ID Longevity and Collagen Complex Powder) on measures of skin condition, hair, sleep…
- Conditions
- Skin Ageing, Healthy Ageing, Effect of Oral Nutritional Supplementation on Skin, Hair, Sleep, Energy, Cognition and Sexual Wellbeing in Healthy Adults, Longevity
- Trial name
- IDF-AID-1 (NCT07827651)
- Testing
- Advanced ID
- Where
- United Kingdom
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- IDI Skincare Limited
Sleep Quality, Quality of Lifte
Electrical Vestibular Nerve Stimulation (VeNS) as a Treatment for Improving Sleep in Visually Impaired Patients
Trial title: Effectiveness of Electrical Vestibular Nerve Stimulation in the Improvement of Sleep in Patients with Visual Impairment.
- Conditions
- Sleep Quality, Quality of Lifte, Non-24 Sleep-Wake Disorder
- Trial name
- NCT06956118
- Testing
- Intervention (VeNS Stimulation) Device
- Where
- India
- Volunteers
- 60 people
- Sponsor
- Neurovalens Ltd.
Sleep
A Single-Group Study to Examine the Efficacy of a Melatonin Lotion With Magnesium to Improve Sleep Quality and Quantity
This study will evaluate the efficacy of Asutra's 'Dream the night away' nighttime lotion with melatonin and magnesium on sleep health in terms of quantity, quality, ease of falling asleep or falling back asleep after waking in…
- Trial name
- NCT06146712
- Testing
- Asutra's 'Dream the night away' nighttime lotion
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Asutra
Insomnia
Appraising Clinical Trial Experiences of Patients With Insomnia
Medical research participation percentages haven't always been fully representative of a given demographic. The goal is to find out which aspects of a clinical trial may make it more difficult for patients to take part or see it…
- Trial name
- NCT05978271
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Power Life Sciences Inc.
Sleep Apnea, Obstructive
Safety of Ramelteon in Subjects With Mild to Moderate Obstructive Sleep Apnea
The purpose of this study is to assess the safety of ramelteon, once daily (QD), in individuals with obstructive sleep apnea.
- Trial name
- NCT00672061
- Where
- 5 sites in United States
- Volunteers
- 26 people
- Sponsor
- Takeda
Sleep Disorder
A Clinical Study on the Improvement of Sleep Quality, Skin Condition and Life Status After Taking Sleep Aid Drinks
The main objective of the study is to observe changes in the subjects' sleep quality, skin condition and life status after 4 weeks of using a sleep aid drink (AOXMED Poria γ-aminobutyric acid drink).
- Trial name
- NCT05908903
- Testing
- Drinks with active ingredients such as poria and GABA
- Where
- China
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Botanee Group Co., Ltd.
Insomnia, Sleep Initiation and Maintenance Disorders
Sleep Efficacy Randomized Evaluation of a Novel Digital Therapeutic for Insomnia
This study is a multicenter, randomized, double-blind, sham-controlled clinical investigation designed to evaluate the effectiveness and safety of BELL-001, a digital therapeutic developed to improve symptoms of insomnia.
- Trial name
- SERENE (NCT07295431)
- Testing
- BELL-001 Digital Therapeutic
- Where
- 6 sites in South Korea
- Volunteers
- 116 people
- Sponsor
- BELL Therapeutics Inc.
Primary Insomnia
Elderly Primary Insomnia Polysomnographic Study (0928-002)(TERMINATED)
The purpose of the study is to test the safety and effectiveness of an Investigational Drug on insomnia in the elderly.
- Trial name
- NCT00094666
- Testing
- MK0928, gaboxadol / Duration of Treatment - 6 weeks
- Volunteers
- 465 people
- Sponsor
- H. Lundbeck A/S
Insomnia Disorder
Phase Ⅰb/Ⅱ Study of HS-10506 in Chinese Participants With Insomnia Disorder
The primary purpose of this phase Ⅰb/Ⅱ study is to investigate the safety, tolerability, pharmacokinetics (the study of the way a drug enters and leaves the blood and tissues over time) after multiple dose administration and the…
- Trial name
- NCT06279286
- Testing
- HS-10506
- Where
- China
- Volunteers
- 312 people
- Sponsor
- Jiangsu Hansoh Pharmaceutical Co., Ltd.
Sleep Disturbance
Clinical Study to Investigate the Sleep Quality Enhancing Effect of GABA
The purpose of this study is to investigate the efficacy and safety of dietary supplement GABA in subjects with mild, transient sleep disorder.
- Trial name
- NCT04857021
- Testing
- GABA
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Amorepacific Corporation
Depressive Disorder, Major
Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptoms
The purpose of this study is to know how well seltorexant works, and also to evaluate safety and maintenance effect of seltorexant compared with placebo as an adjunctive therapy to an antidepressant in improving depressive…
- Trial name
- NCT06559306
- Testing
- Seltorexant, Selective Serotonin Reuptake Inhibitor (SSRI)/Serotonin-Norepinephrine Reuptake Inhibitor (SNRI)
- Where
- 205 sites in United States, Argentina and 14 more
- Volunteers
- 752 people
- Sponsor
- Janssen Research & Development, LLC
Insomnia
A Study to Evaluate the Pharmacokinetics of LY2624803 in Subjects With Hepatic Impairment
The purpose of this study is to evaluate the impact of hepatic dysfunction on the pharmacokinetics and safety of LY2624803 and its major metabolite, LSN2797276.
- Trial name
- NCT01257178
- Testing
- LY2624803
- Where
- 4 sites in Germany, Hungary and 1 more
- Volunteers
- healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Parkinson's Disease
Randomized Evaluation of the 24-Hour Coverage: Efficacy of Rotigotine
The objective of this trial is to assess the effects of transdermal rotigotine on the control of early morning motor function and sleep disorders compared to placebo in subjects with idiopathic Parkinsons´s disease.
- Trial name
- RECOVER (NCT00474058)
- Testing
- Rotigotine
- Where
- 47 sites in United States, Australia and 10 more
- Volunteers
- 287 people
- Sponsor
- UCB Pharma
Sleep Initiation and Maintenance Disorders
Disturbed Sleep Model Study.
Subjects will be screened within 28 days. Each treatment session will consist of 2 PSG nights, study drug administration and noise model is conducted on second night.
- Trial name
- NCT00440323
- Testing
- SB-649868, Zolpidem
- Where
- United Kingdom
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline