Clinical trials: Insomnia Disorder
Hypertension, Insomnia
Sleep Quality and Mechanisms of Cardiovascular Risks in Adults With Hypertension
The objective of this study is to elucidate the potential mechanisms responsible for the increased risk of cardiovascular disease among patients with hypertension and comorbid insomnia.
- Trial name
- NCT04009447
- Testing
- Cognitive Behavioral Therapy for Insomnia (CBT-I)
- Where
- United States
- Volunteers
- 149 people
- Sponsor
- Duke University
Vision; Disorder, Loss, Caregiver Burnout
Virtual Health Education vs Meditation in Irreversible Age-Related Vision Loss Patients and Their Caregivers
Vision loss is common among older adults and leads to an increased risk for depression and difficulties in daily tasks, thus requiring dependence on caregivers.
- Conditions
- Vision; Disorder, Loss, Caregiver Burnout, Quality of Life, Depression
- Trial name
- NCT04583748
- Testing
- Sahaj Samadhi Meditation, Health Enhancement Program
- Volunteers
- healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Insomnia
Acupressure for Insomnia
The purpose of this study is to examine the effect of 6-weeks of relaxation acupressure compared to stimulating acupressure or a standard of care on sleep and daytime functioning.
- Trial name
- AcuSnooze (NCT01378793)
- Testing
- Relaxation Acupressure, Stimulating Acupressure
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Michigan
Breast Cancer, Insomnia
Double-blind Randomized Controlled Trial Comparing Suvorexant 20 mg to Placebo for Treatment of Insomnia in Cancer Survivors
Investigators propose a double-blind, placebo-controlled trial evaluating the use of the use of Suvorexant in breast cancer survivors on selective estrogen receptor modulators or aromatase inhibitors with sleep disturbance to…
- Trial name
- NCT06162663
- Testing
- Suvorexant Tablets
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Medical University of South Carolina
Multiple Sclerosis
Caregiver Burden in Caregivers of Patients With Multiple Sclerosis
Individuals aged 18-80 years who have been clinically diagnosed with multiple sclerosis and their caregivers will be included in the study.
- Trial name
- NCT07549048
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Sleep Initiation and Maintenance Disorders
CLINICAL TRIAL PHASE II, MULTICENTRIC, NATIONAL, DOUBLE-BLIND, PARALLEL, RANDOMIZED, AND PLACEBO-CONTROLLED FOR EVALUATION OF THE IMPROVEMENT OF SLEEP QUALITY IN PARTICIPANTS OF RESEARCH WITH INSOMNIA DISORDER
QUALI-001 code Phase II. Multicentric type. Test Product (QUALI-50) and (QUALI-75). Control Placebo capsule Primary goal Evaluate the improvement in sleep quality through the evaluation comparison of Pittsburgh Sleep Quality…
- Trial name
- NCT05753943
- Testing
- QUALI
- Sponsor
- Federal University of São Paulo
Insomnia
Effect of Low Level Light Irradiation on Insomniacs' Meridians During the First Sleep Cycle.
Introduction In the past, it was found that stimulating the meridians and acupoints with low-level light often had a good effect.
- Trial name
- NCT05426226
- Testing
- laser acupuncture
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Mood Disturbance
Effect of Saffron Extract Supplementation on Emotional Well-being Alterations
This study aims to test whether a saffron extract represents a good candidate to improve emotional well-being in subjects with subclinical symptoms of depression, fatigue, stress or anxiety.
- Trial name
- SAFFROMFOOD (NCT05690126)
- Testing
- Saffron extract, Maltodextrin
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
Relaxation Program, Anxiety
Effects of Benson Relaxation Exercise on Anxiety Level and Sleep Quality in Adolescents
Purpose: The purpose of this study is to examine the effects of Benson relaxation exercise applied to children and adolescents receiving inpatient treatment in a psychiatric clinic on anxiety levels and sleep quality.
- Conditions
- Relaxation Program, Anxiety, Sleep Quality, Psychiatric Hospitalization
- Trial name
- BRE (NCT06661304)
- Testing
- Benson Relaxation Exercise, Ongoing treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Uskudar University
Insomnia
Feasibility of Internet Group CBT-I for Gyn Oncology Patients
The goal of this study is to evaluate the feasibility and acceptability of delivering cognitive behavioral therapy for insomnia (CBT-I) to gynecologic cancer patients in an internet-based small-group setting.
- Trial name
- NCT06060158
- Testing
- Cognitive Behavioral Therapy for Insomnia
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of California, Davis
Stress Resilience, Systemic Inflammation
Oral Supplementation With 1 mg of KGA-10 Daily (a Novel Environmentally-derived Mycolicibacterium) for Stress, Sleep, and Inflammation
The goal of this clinical trial is to learn if a novel strain of heat-killed Mycolicibacterium that is being considered by the International Code of Nomenclature of Prokaryotes (ICNP) as candidate species and type strain…
- Conditions
- Stress Resilience, Systemic Inflammation, General Wellbeing, Sleep Quality
- Trial name
- NCT07604038
- Testing
- Mycolicibacterium petrae KGA-10 (heat-killed)
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Kioga Inc.
Anxiety, Insomnia
Augmenting Benzodiazepine Receptor Agonist Deprescribing With Acupuncture and Yoga Among Older Adults
The main purpose of this 12-week study is to see if a new combination of treatments can help older adults reduce benzodiazepine or related medication use.
- Conditions
- Anxiety, Insomnia, Benzodiazepine, Deprescription
- Trial name
- NCT06197243
- Testing
- Acupuncture, Yoga, Deprescribing
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Familial Fatal Insomnia
Familiar Fatal Insomnia: Preventive Treatment With Doxycycline in Subject With Disease Risk
The neurodegenerative disorders is a class o pathologies including very common diseases as Alzheimer or Parkinson or very rare as fatal familial insomnia (FFI), the progression of the disease with no therapeutic remedy is the…
- Trial name
- FFI (NCT04846335)
- Testing
- Doxycycline Hcl
- Volunteers
- 29 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Insomnia, Sleeplessness
Efficacy of Wholetones® 2Sleep Music on Health and Sleep Behaviors of Healthy Adults With Insomnia Symptoms
(b) The investigators propose to conduct a four-week randomized controlled crossover trial on healthy adults with occasional sleeplessness to examine the efficacy of Wholetones music on their health-related quality of life, sleep…
- Trial name
- NCT03928301
- Testing
- Wholetones Music, Classical Music
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Jacksonville University
Sleep Initiation and Maintenance Disorders
A Double-blind, Group-comparison P-III Study With Zolpidem MR Using Placebo and Nitrazepam in Insomnia Patients
A multicenter, randomized, double-blind, triple-dummy, group-comparison study using placebo and nitrazepam as a comparative drug.
- Trial name
- NCT00374777
- Testing
- zolpidem MR, nitrazepam
- Where
- 6 sites in Japan
- Volunteers
- 450 people
- Sponsor
- Astellas Pharma Inc
Insomnia, Stress
Evaluation of the Effects of Saffron Extract on Sleep Quality and Stress
Therefore, the aim of this study was to confirm by a randomized double-blind controlled study the beneficial effects of saffron extract (Saffr'activ®) on sleep quality in subjects presenting mild to moderate sleep disorder…
- Trial name
- NCT04750681
- Testing
- Saffron
- Where
- Belgium
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Comercial Quimica Masso, S.A
Chronic Pain, Anxiety
Phase II Trial of Nu-V3 Non-Invasive Nerve Stimulation Device for Chronic Pain, Anxiety, Depression, Sleeplessness
This Nu-V3 clinical study is a randomized, phase II, open-label study evaluating the Nu-V3 cranial nerve stimulation treatment device in patients with chronic pain, anxiety, depression, and/or sleeplessness.
- Conditions
- Chronic Pain, Anxiety, Depression, Sleeplessness
- Trial name
- Nu-V3P2RCT (NCT05394545)
- Testing
- Nu-V3
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Nu-Life Solutions
Insomnia
A Preliminary Study of Model-driven Individualized Transcranial Electrical Stimulation for Insomnia
This study is designed to evaluate the efficacy and to explore the best individualized stimulus paradigm of transcranial Electrical Stimulation for insomnia patients.
- Trial name
- NCT05445999
- Testing
- High-Definition transcranial electrical stimulation
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Shanghai Mental Health Center
CNS
2-Part Multiple Ascending Dose Study for Safety and Pharmacokinetics in Healthy and Elderly Subjects
This is a single-center, randomized, double-blind, placebo-controlled, sequential, multiple-dose study. The study will be conducted in two parts: Part A (6 cohorts of healthy adults receiving evening dosing) and Part B (one…
- Trial name
- NCT01673451
- Testing
- E2006
- Where
- 2 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Eisai Inc.
Insomnia
Gabapentin's Effects on Insomnia in Patients With Recent Concussion
In this open-label, pilot study the investigators will be assessing gabapentin's effects on insomnia and other concussion-related symptoms in patients with a recent concussion experiencing insomnia.
- Trial name
- NCT01421264
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- State University of New York at Buffalo