Clinical trials: Inspiratory Resistance
Snoring, Apnea, Obstructive
Dental Appliance to Treat SDB in Children
The clinical hypothesis of this study is that a currently marketed mouthguard may also be able to reduce the symptoms of sleep-disordered breathing in children.
- Conditions
- Snoring, Apnea, Obstructive, Upper Airway Resistance Syndrome, Sleep-Disordered Breathing
- Trial name
- NCT05661747
- Testing
- Vivos Grow/Vivos Way Device
- Where
- 4 sites in United States
- Volunteers
- 50 people
- Sponsor
- Vivos BioTechnologies, Inc.
Aging
The Effect of Age and Inspiratory Resistance on the Inspiratory Gas Levels While Wearing Air Purifying Respirator "
20 healthy young subjects and 20 healthy older subjects will go through a medical examination. Subjects will be asked for their medical history especially on respiratory and cardiac diseases.
- Trial name
- NCT03522493
- Testing
- "Yaalom Katom"
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Medical Corps, Israel Defense Force
Right-heart Hemodynamics, Respiratory Muscle Training
Inspiratory Muscle Training During Right-heart Catheterization
The purpose of this study is to assess hemodynamic effects of inspiratory muscle training during routinely performed right-heart catheterization.
- Conditions
- Right-heart Hemodynamics, Respiratory Muscle Training, Inspiratory Resistance
- Trial name
- NCT02054728
- Testing
- RHC and IMT
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Wissenschaftliches Institut Bethanien e.V
Cystic Fibrosis, Pseudomonas Aeruginosa
A Comparator Study Evaluating Microbiological Resistance and Effects of Alternating Inhaled Antibiotic Therapies
This is a pilot study of inhaled antibiotic regimens is a pilot study examining clinical and laboratory endpoints of patients on inhaled antibiotic treatments.
- Trial name
- NCT01319253
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Indiana University
Non-Tuberculous Mycobacterial Pneumonia
Prolonged-Use of Inhaled Gaseous Nitric Oxide (gNO) for Adult With Non-Tuberculous Mycobacteria Infection
An open labeled Study (NCT03331445) is demonstrating encouraging safety and efficacy results for most subjects receiving 160ppm nitric oxide gas (gNO) for treatment of non-tuberculous mycobacteria (NTM) over a 15 day treatment…
- Trial name
- NCT03473314
- Testing
- Nitric Oxide gas at 160ppm
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- University of British Columbia
Ventilator Associated Pneumonia ( VAP)
Role of Inhaled Polymyxin as an Adjunct to Intravenous Therapy in Multidrug Resistant Ventilator-associated Pneumonia in Stroke Patients
This study investigates whether adjunctive inhaled colistin enhances clinical recovery and microbiological clearance in multidrug resistant ventilator-associated pneumonia in stroke patients
- Trial name
- NCT07865871
- Testing
- Inhaled colistin, Saline
- Volunteers
- 78 people
- Sponsor
- Ain Shams University
Asthma, COPD
The Natural History of Small Airways Physiology in Diseased and Healthy States
Spirometry is a useful clinical tool for the assessment and monitoring of lung disease, however, it does not provide information on peripheral airways resistance.
- Conditions
- Asthma, COPD, Interstitial Lung Disease, Cystic Fibrosis
- Trial name
- NCT00677560
- Where
- United Kingdom
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Type 1 Diabetes Mellitus
Comparison of Technosphere Insulin Inhalation Powder & Subcutaneous Rapid-Acting Analog in Subjects With Type 1 Diabetes
This is an Open-label, randomized study in Type 1 diabetics looking at exposure and response (PK/PD) of TI using GEN2C Inhaler versus rapid acting analog.
- Trial name
- NCT01544881
- Testing
- Technosphere Insulin Inhalation Powder, Rapid Acting Analog
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Mannkind Corporation
Fibromyalgia, Fibromyalgia Syndrome
Slow Breathing and Resistance Exercise in Fibromyalgia
This randomized controlled trial investigates whether slow breathing techniques influence heart rate variability, exercise self-efficacy, and resistance exercise performance in women with fibromyalgia.
- Trial name
- Breath-fibro (NCT07404384)
- Testing
- Slow Breathing with Visual Pacer, Slow Breathing without Visual Pacer, Spontaneous Breathing (Active Control)
- Where
- 2 sites in Spain
- Volunteers
- 159 people
- Sponsor
- University of Malaga
Diabetes Mellitus, Type 2, Hypertension
Inspiratory Muscle Strength Training in Adults With Type 2 Diabetes
This clinical research study will investigate the effects of 6 weeks of inspiratory muscle strength training on metabolic and cardiovascular outcomes in adults with recent-onset type 2 diabetes.
- Trial name
- DIT (NCT05643768)
- Testing
- Inspiratory muscle strength training (IMST)
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Arizona
Ventilator Associated Pneumonia
Efficacy Study of Colistimethate Sodium Inhalation in Patients With Ventilator-associated Pneumonia
There might be additional benefit on clinical outcomes from adjunctive colistimethate sodium inhalation as therapy for multidrug resistant Gram-negative ventilator-associated pneumonia.
- Trial name
- NCT01975350
- Where
- Taiwan
- Volunteers
- 49 people
- Sponsor
- National Taiwan University Hospital
Cardiovascular Abnormalities, Post-COVID-19 Syndrome
Inspiratory Muscle Strength Training in Post-Covid Syndrome
Patients with post-Covid-19 syndrome are at high risk of developing cardiovascular diseases 12 months after acute infection of COVID-19.
- Conditions
- Cardiovascular Abnormalities, Post-COVID-19 Syndrome, Physical Exercise
- Trial name
- NCT06091384
- Testing
- Inspiratory muscle strength training
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- D'Or Institute for Research and Education
Asthma
No Resistance After Long Term Treatment SERETIDE
This multi centre, double blind, comparator controlled, parallel group study is to determine whether asthma treatment with high doses of fluticasone propionate (FP) redirects a Th2/ eosinophil response towards a more treatment…
- Trial name
- NCT00456313
- Testing
- FLIXOTIDE and SERETIDE
- Where
- 2 sites in Netherlands
- Sponsor
- GlaxoSmithKline
Type 1 Diabetes
Afrezza With Basal Combination (ABC): Afrezza® Combined With AID Pump or Insulin Degludec in Adults With Type 1 Diabetes
A phase 4 study evaluating the efficacy of mealtime control with Afrezza in combination with an automated insulin pump or insulin degludec in adult subjects with type 1 diabetes
- Trial name
- ABC (NCT05243628)
- Testing
- Afrezza (insulin human) Inhalation Powder, insulin degludec, Continuous Subcutaneous Insulin Infusion (CSII) pump with Automatic Insulin Delivery (AID)
- Where
- 2 sites in United States
- Volunteers
- 33 people
- Sponsor
- Mannkind Corporation
Obesity, Metabolic Syndrome
Effects of Bariatric Surgery on Inspiratory Metaboreflex in Obese Subjects
The hypothesis of this study is that reductions in body weight could improve inspiratory muscle function attenuating the inspiratory metaboreflex in metabolically healthy obese individuals and obese individuals with metabolic…
- Trial name
- NCT03056937
- Testing
- Bariatric surgery, Control
- Where
- Brazil
- Volunteers
- 45 people
- Sponsor
- University of Cruz Alta
Cervical Spinal Cord Injury, Cervical Cord Injuries Spinal
Low Volume Nose Resistance Breathing Exercise With Incentive Spirometer in Patient With Cervical Spinal Cord Injuries
This randomized clinical trial aims to evaluate the effectiveness of combining Low Volume Nose Resistance Breathing Exercises (LVNRBE) with Incentive Spirometry (IS) on respiratory outcomes in patients with cervical spinal cord…
- Trial name
- NCT07645027
- Testing
- Acapella device plus Incentive Spirometry, conventional respiratory physiotherapy
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Obstructive Sleep Apnea, Sleep Apnea
Effects of Continuous Positive Airway Pressure (CPAP) on Glucose Metabolism
Obstructive sleep apnea affects approximately 2-4% of middle-aged adults in the general population and is associated with several medical conditions including hypertension and coronary artery.
- Conditions
- Obstructive Sleep Apnea, Sleep Apnea, Sleep-disordered Breathing
- Trial name
- SOMNOS (NCT01503164)
- Testing
- Positive Pressure Therapy (PAP), LifeStyle Counseling
- Where
- United States
- Volunteers
- 111 people
- Sponsor
- Johns Hopkins University
Respiratory Insufficiency
Non-invasive Measurements of Elastance and Resistance
The study aims to assess the agreement between respiratory mechanics parameters measured noninvasively by means of brief airways occlusions at the beginning of inspiration and the reference parameters obtained with standard…
- Trial name
- ERNI (NCT01530282)
- Testing
- Invasive method, Non invasive method
- Volunteers
- 15 people
- Sponsor
- University of Turin, Italy
Stress, Breathing Exercise
Real World Assessment of Resistance Breathing Device
The purpose of this study is to examine the usability and effectiveness of a stress management device during an academic exam period and asks the following questions: To what extent is a resistance breathing device (AIRpen)…
- Conditions
- Stress, Breathing Exercise, Stress Management
- Trial name
- NCT07187349
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Livotion, LLC
Bronchiectasis
Inspiratory Flow and Volumes in Bronchiectatics
Adequate administration of drugs via dry powder inhalers is dependent on adequate inspiratory flow rates and volumes. These vary according to the device being used and its resistance.
- Trial name
- NCT00656565
- Where
- Australia
- Volunteers
- 15 people
- Sponsor
- Syntara