Clinical trials: Inspiratory Resistance
Respiration Disorders
Elastic-Band Resistance and Breathing Training for Older Adults With Pulmonary Function Impairment
The goal of this clinical trial is to learn whether elastic-band resistance training, with or without breathing training, can improve lung function and physical function in older adults with pulmonary function impairment living…
- Trial name
- EBBT-PFI (NCT07612072)
- Testing
- Elastic-Band Resistance Training Plus Breathing Training, Elastic-Band Resistance Training
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Beijing Sport University
Severe Asthma, COPD
Predictive Value of Spirometric PIF to Produce PIF Rate Needed for the Use of Current DPI's.
The main aim is to study correlations between Peak inspiratory flow measured during a spirometry (PIFspiro) and Peak inspiratory flow measured over a pre-set resistance (PIFresist) in COPD patients and severe asthma patients.
- Trial name
- NCT03377920
- Testing
- In-check Dial device (Clement Clarke International Ltd, Harlow, UK)
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Universitair Ziekenhuis Brussel
Vagus Nerve Stimulation, Insulin Sensitivity
Effect of Breathing Maneuvers on Peripheral Glucose Metabolism
Two important mechanisms play a major role in the pathogenesis of type 2 diabetes: insulin resistance of the target tissues and the impaired insulin secretion from pancreatic β-cells.
- Conditions
- Vagus Nerve Stimulation, Insulin Sensitivity, Deep Breathing Maneuver
- Trial name
- RESPI01 (NCT04150627)
- Testing
- deep breathing
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Heart Failure
High-intensity vs. Low-intensity Inspiratory Muscle Training in Patients With Heart Failure
It is well-known that muscle weakness and deconditioning play an important role in low exercise capacity of patients with HF. Interestingly, not only peripheral muscles are impaired, but also respiratory muscles.
- Trial name
- NCT03247361
- Testing
- High-intensity IMT + Aerobic/resistance exercise, Low-intensity IMT + Aerobic/resistance exercise
- Where
- Brazil
- Volunteers
- 90 people
- Sponsor
- Federal University of Bahia
Apnea, Sleep, Chronic Fatigue Syndrome
Sleep Disordered Breathing in Gulf War Illness and the Effect of Nasal CPAP Treatment
The purpose of this study is to determine any sleep disordered breathing in veterans with Gulf War Syndrome (GWS) and compare it to healthy normal asymptomatic Gulf War veterans.
- Trial name
- NCT00252629
- Testing
- Nasal CPAP treatment during sleep
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- US Department of Veterans Affairs
Cystic Fibrosis, Methicillin-resistant Staphylococcus Aureus
Pharmacokinetics of Vancomycin for Inhalation in Cystic Fibrosis
The purpose of this study is to determine the pharmacokinetics and safety of inhaled vancomycin in patients with cystic fibrosis.
- Trial name
- NCT01509339
- Testing
- Vancomycin
- Where
- United States
- Sponsor
- Case Western Reserve University
Pulmonary Arterial Hypertension (PAH), Pulmonary Vascular Disease
Assessment of Total Pulmonary Resistance sPAP/CO Between High Altitude HA vs. Sea Level LA in Patients With Pulmonary Arterial Hypertension PAH
To study the effect of relocation from high altitude (Quito Ecuador: 2850m) to sea level on pulmonary resistance (sPAP/CO) and other hemodynamic outcomes in patients with pulmonary arterial hypertension PAH, who live permanently…
- Conditions
- Pulmonary Arterial Hypertension (PAH), Pulmonary Vascular Disease, High Altitude, Echocardiography
- Trial name
- NCT07804524
- Testing
- Descent from 2850m to sea level
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Silvia Ulrich Somaini
Ventilator Acquired Pneumonia
Study to Determine Quicker Methods of Diagnosing Pneumonia Caused by a Breathing Machine in Critically Ill Patients
Critically ill patients on a breathing machine are at risk of developing a type of pneumonia called Ventilator Acquired Pneumonia (VAP).
- Trial name
- NCT00938002
- Testing
- Acceler8 Pheno
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Denver Health and Hospital Authority
Mechanical Ventilation, Pneumonia
Removal of Endotracheal Tube Secretions Comprehensively Until Extubation
The purpose of this study is to measure secretion accumulation within endotracheal tubes of mechanically ventilated patients and test the efficacy, safety and clinical impact of removing the secretions using novel airway…
- Trial name
- RESCUE (NCT00663637)
- Testing
- CAM (Complete Airway Management) Catheters
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- O. M. Neotech, Inc.
Healthy Adult Male
Wearable Resistance Vest for Strengthening Respiratory Muscles
Respiratory muscle weakness significantly limits functional capacity in various populations, yet conventional respiratory muscle training (RMT) often requires coached, mouthpiece-based maneuvers that may be limited by technique…
- Trial name
- WEARVEST (NCT07698873)
- Testing
- Wearable Resistance Vest
- Where
- Saudi Arabia
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
COVID-19 Pandemic
Effects of Diagrammatic Breathing With and Without Resistance in Post Covid Patients on ADLs
Effects of diaphragmatic breathing exercise with and without resistance exercise program on functional capacity and activity of daily living in post covid patients
- Trial name
- NCT05543551
- Testing
- Diaphragmatic breathing with Resistance Training, diaphragmatic breathing with out resistance training
- Where
- Pakistan
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Pneumonia, Ventilator-Associated
Tobramycin Nebulization to Prevent Multidrug-Resistant Ventilator-Associated Pneumonia
The TOP-MDRVAP trial will test whether inhaled tobramycin can safely prevent pneumonia caused by multidrug-resistant bacteria in adults who need a breathing machine. Tobramycin is an antibiotic.
- Trial name
- TOP-MDRVAP (NCT07856355)
- Testing
- Tobramycin inhalation solution
- Where
- China
- Volunteers
- 574 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Severe Mental Disorder
Aerobic, Resistance and Inspiratory Muscle Training in Adults With Severe Mental Disorder
People with severe mental disorder, such as schizophrenia, bipolar disorder or major depression, tend to have poorer physical health and a shorter life expectancy than the general population.
- Trial name
- NCT07758049
- Testing
- Supervised multicomponent exercise programme
- Where
- Spain
- Volunteers
- 49 people
- Sponsor
- Universidad Pablo de Olavide
Idiopathic Pulmonary Fibrosis, Progressive Pulmonary Fibrosis
Inspiratory Flow Rate Capability in Pulmonary Fibrosis Patients
The goal of this observational study is to learn about the inspiratory flow rate capability in patients with pulmonary fibrosis (IPF or PPF) when using inhaler devices with different resistances.
- Trial name
- NCT07820254
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai Pulmonary Hospital, Shanghai, China
Chronic Obstructive Pulmonary Disease
IMT in Ventilatory Muscle Metaboreflex in COPD
This research intends to evaluate if inspiratory muscle training (IMT) reduces inspiratory muscle metaboreflex through the decrease of calf vascular resistance and increase of calf blood flow in Chronic Obstructive Pulmonary…
- Trial name
- NCT01945398
- Testing
- Inspiratory Muscle Training
- Where
- Brazil
- Volunteers
- 13 people
- Sponsor
- Federal University of Rio Grande do Sul
Pneumonia
Phase I Single-blind Clinical Trial to Evaluate the Safety and Local Immune Activation of a Toll-like Receptor 5 Agonist (FLAMOD) Administered by Aerosol
This is a single-blind, randomized, placebo-controlled, dose-escalation phase I monocentric trial assessing a single administration of FLAMOD by aerosol in healthy subjects.
- Trial name
- NEBUFLAG (NCT06681402)
- Testing
- FLAMOD
- Where
- France
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Diabetes Mellitus, Type 2
A Clinical Trial Comparing the Efficacy and Safety of Exubera® and Lantus®
To compare efficacy and safety of Exubera® vs Lantus® in patients with type 2 diabetes mellitus.
- Trial name
- NCT00391027
- Testing
- Insulin Glargine (Lantus®), Inhaled Human Insulin (Exubera®)
- Where
- 62 sites in Belgium, Finland and 8 more
- Volunteers
- 261 people
- Sponsor
- Pfizer
Lung Transplantation
Impact of Inspiratory Muscle Training (IMT) With Intermittent Variable Resistance (IVR) Versus Constant Resistance (CR) on Functional Capacity in Lung Transplantation (LTx) Patients (I-TRAIN-LTx Study)
Objectives: Primary Objective: To compare Maximum Inspiratory Pressure (MIP) in lung transplant (LT) patients between the use of inspiratory muscle training (IMT) with intermittent variable resistance (IVR) or constant resistance…
- Trial name
- I-TRAIN-LTx (NCT06963190)
- Testing
- Constant Resistance (CR), Intermittent Variable Resistance (IVR)
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- Hospital Universitario Marqués de Valdecilla
Multiple Sclerosis
Fatigue and Inspiratory Muscles Training in Patients With Multiple Sclerosis
The purpose of this study is to assess the effect of a training of the inspiratory muscles against resistance at home during 10 weeks in multiple sclerosis patients with a severe disability.
- Trial name
- AIRSEP (NCT02726672)
- Testing
- respiratory rehabilitation using Powerbreathe
- Where
- France
- Volunteers
- 46 people
- Sponsor
- Lille Catholic University
Lung Neoplasm Malignant
Resistance Inspiratory Muscle Training for Patients With Thoracic Malignancies
A small-scale pilot randomized controlled trial conducted by the investigators demonstrated some preliminary evidence that inspiratory muscle training (IMT) could be a promising self-management method for alleviating…
- Trial name
- NCT03834116
- Testing
- Inspiratory muscle training
- Where
- China
- Volunteers
- 196 people
- Sponsor
- The Hong Kong Polytechnic University