Clinical trials: Insufflation
Colonoscopy Education
Comparing Clinical Performance of Novice Trainee Endoscopists Using Conventional Air Insufflation Versus Warm Water Infusion Colonoscopy
Hypothesis: Novice trainees will achieve significantly higher clinical competence and patient satisfaction scores with the use of warm water infusion method when compared with traditional air insufflation Primary outcome: adenoma…
- Trial name
- NCT01482546
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Respiratory Failure, Weaning Failure
HVNI for Successful Weaning in Respiratory Failure
The goal of this randomized active-controlled study is to investigate the role of high velocity nasal insufflation (HVNI) in the immediate post-extubation period and compare it with non-invasive positive pressure ventilation…
- Trial name
- REVIVER (NCT05855213)
- Testing
- High Velocity Nasal Insufflation, Non-invasive positive pressure ventilation
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Alexandria University
Failed or Difficult Intubation, Adenoma
Water Method in Patients With Incomplete Colonoscopy
Water method with water exchange has been shown to reduce medication requirement and pain experienced during colonoscopy. It increases the success rate of cecal intubation in sedated and unsedated patients undergoing screening…
- Conditions
- Failed or Difficult Intubation, Adenoma, Pain
- Trial name
- NCT01546246
- Testing
- Water colonoscopy
- Where
- China
- Sponsor
- Air Force Military Medical University, China
Mucus Retention, Mechanical Ventilation Complication
Efficacity and Safety of Mechanical Insufflation-exsufflation on ICU
Critically ill and intubated patients on mechanical ventilation (IMV) often present retention of respiratory secretions, increasing the risk of respiratory infections and associated morbidity.
- Conditions
- Mucus Retention, Mechanical Ventilation Complication, Mucus; Plug, Tracheobronchial
- Trial name
- NCT03316079
- Testing
- Chest physiotherapy techniques, Mechanical insufflation-exsufflation
- Where
- 3 sites in France
- Volunteers
- 26 people
- Sponsor
- University Hospital, Bordeaux
General Anesthesia
The Comparison of the Effect of Pressure-controlled Ventilation and Volume-controlled Ventilation on the Gastric Insufflations in I-gel
The purpose of this study is to investigate whether the pressure controlled ventilation can reduce gastric insufflation compared to the volume controlled ventilation in patients who were mechanically ventilated with the i-gel.
- Trial name
- NCT02466295
- Testing
- Volume-controlled ventilation, Pressure-controlled ventilation
- Where
- South Korea
- Volunteers
- 68 people
- Sponsor
- Yonsei University
Abdominal Pain
Carbon Dioxide Insufflation Versus Conventional Air Insufflation
The safety and effectiveness of esophagogastroduodenoscopy and colonoscopy in the detection of gastrointestinal-tract pathology in children has been established during the last three decades.
- Trial name
- NCT02790359
- Testing
- Air, Carbon dioxide
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Medical College of Wisconsin
Esophageal Motility Disorders
U-POEM vs CO2-POEM
Multicenter randomized trial comparing post-procedural pain intensity after Per-Oral endoscopic myotomy (POEM) between two types of standard of care insufflation methods (CO2 vs Underwater).
- Trial name
- U-POEM (NCT06918730)
- Testing
- U-POEM, CO2-POEM
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- AdventHealth
Warm Water, CO2 Colonoscopy
Carbon Dioxide Insufflation (CO2) and Warm Water Infusion (WWI) Versus Standard Air Insufflation (AI) for Unsedated Colonoscopy
Due to the increasing demand for colonoscopy in clinical practice, great interest has recently renewed for unsedated colonoscopy.
- Conditions
- Warm Water, CO2 Colonoscopy, Unsedated Colonoscopy
- Trial name
- NCT01259583
- Testing
- CO2, Warm water
- Where
- Italy
- Volunteers
- 341 people
- Sponsor
- Valduce Hospital
Anesthesia
Evaluation of Lung Atelectasis During Apneic Oxygenation Using THRIVE in Adults During Laryngeal Surgery.
Oxygenation with high-flow nasal cannula with 100% oxygen have now been evaluated in a number of studies and the data are convincing.
- Trial name
- A-THRIVE (NCT03458091)
- Testing
- THRIVE, Endotracheal intubation
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Karolinska University Hospital
Cholelithiasis
The Effect of Preoxygenation on Gastric Decompression in Laparoscopic Cholecystectomies
Aim: Gastric insufflation caused by mask ventilation during laparoscopic surgeries may affect the surgical field, lead to regurgitation of gastric contents, and consequently cause aspiration pneumonia.
- Trial name
- NCT07274488
- Testing
- Preoxygenation, Mask Ventilation
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Ankara City Hospital Bilkent
Apnea, Ventilation Therapy; Complications
THRIVE Apneic Ventilation With Standardized Airway Management During General Anesthesia.
Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) denotes the use of high-flow humidified nasal oxygen system (for example Optiflow®) as an alternative ventilation modality for an anesthetized patient without…
- Conditions
- Apnea, Ventilation Therapy; Complications, Respiratory Acidosis
- Trial name
- NCT03797859
- Testing
- Apneic ventilation
- Where
- 2 sites in Denmark
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Pre-oxygenation in Term Pregnant Women
Clinical Trial of Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) Oxygen in Women Having Planned Caesarean Delivery
Clinical Trial of Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) Oxygen in Women having Planned Caesarean Delivery.
- Trial name
- THRIVEN90 (NCT04229745)
- Testing
- THRIVE pre-oxygenation
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- SABA AL-SULTTAN
Pneumoperitoneum
Different Insufflation Flows and Effects on Cerebral Oxygenation in Laparoscopic Cholecystectomy
Previous studies conducted on the hemodynamic effects of pneumoperitoneum pressures created by different insufflation flows are very limited in the literature.
- Trial name
- NCT05992636
- Testing
- pneumoperitoneum insufflation (flow) rate
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people
- Sponsor
- Karadeniz Technical University
Right Colon Adenoma Detectation Rate, Water Exchange Colonoscopy
Right Colon Adenoma Detection Rate Using Water Exchange Versus Air Insufflation in Colonoscopy.
Although colonoscopy is currently regarded as the gold standard to detect and prevent colorectal cancer (CRC) but post-colonoscopy CRCs (interval cancer, IC) still occur.
- Trial name
- NCT07456007
- Testing
- Right colon water exchange, Air nsufflation
- Where
- Taiwan
- Volunteers
- 414 people
- Sponsor
- Dalin Tzu Chi General Hospital
Surgery, Anesthesia Intubation Complication
MAsk VEntilation With Paratracheal Pressure In Children. Para Tracheal Compression to Prevent Gastric Insufflation in Children
The use of cricoid pressure to prevent gastric aspiration or regurgitation in case of "full stomach" situation or emergency is still controversial in the adult population.
- Trial name
- MAVEPPIC (NCT05279170)
- Testing
- MAVEPPIC: MAsk VEntilation with Paratracheal Pressure In Children
- Where
- 2 sites in France
- Volunteers
- 72 people
- Sponsor
- University Hospital, Lille
Pain, Postoperative
Comparison of AirSeal to DV5 Insufflation in Gastric Sleeve Procedures - The "CAT5-GS" Study
A study to compare two different insufflation devices during robotic laparoscopic sleeve gastrectomy surgery, AirSeal to DV5 insufflation, in Gastric Sleeve Procedures. Shoulder, neck and chest pain will be assessed.
- Trial name
- "CAT5-GS" (NCT07312006)
- Testing
- AirSeal Insufflation system, DV5 Insufflation system
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- SurgiQuest, Inc.
Bariatric Surgery
Lexion AP 50/30 Warmed Humidified Real Time CO2 Insufflation vs Airseal Recirculated CO2/Air Insufflation in Minimally Invasive Bariatric (Gastric Bypass) Surgery
The purpose of this study is to To determine the effect of warm and humidified (WH) carbon dioxide (CO2) on post-operative pain/analgesia requirement in patients undergoing laparoscopic bariatric surgery.
- Trial name
- NCT05838300
- Testing
- Warm humidified CO2, Dry CO2
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- The University of Texas Health Science Center, Houston
Obesity Hypoventilation Syndrome (OHS)
HVNI Versus NIV In Management Of Acute Hypercapnic Respiratory Failure In OHS
1. Assessment of benefits of HVNI in management of obesity hypoventilation syndrome complicated with acute hypercapnic respiratory failure. 2.
- Trial name
- NCT05805293
- Testing
- High-Velocity Nasal Insufflation Therapy, Non-Invasive Ventilation
- Volunteers
- 56 people
- Sponsor
- Assiut University
Gastric Distention
High Flow Nasal Oxygenation and Gastric Insufflation in Anesthetized Patients
Transnasal humidified rapid-insufflation ventilatory exchange(THRIVE), or also termed high flow nasal oxygenation (HFNO) is a method of supplying heated, humidified high concentrations of oxygen via nasal cavity.
- Trial name
- NCT04629911
- Testing
- THRIVE
- Where
- South Korea
- Volunteers
- 45 people
- Sponsor
- Ajou University School of Medicine
Colorectal Cancer
RCT of Air Insufflation Versus Water Infusion Colonoscopy by Supervised Trainees
Our aim is to perform a randomized-controlled trial comparing air insufflation sedated colonoscopy (conventional method) vs. water infusion sedated colonoscopy (study method) by supervised trainees.
- Trial name
- NCT00841282
- Testing
- Colonoscopy for colorectal cancer screening, Water Infusion Colonoscopy, Air insufflation colonoscopy
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- East Bay Institute for Research and Education