Clinical trials: Insulin Resistance Syndrome X
Exercise Therapy, Metabolic Syndrome X
Exercise Training Effects on Metabolic Syndrome: Interactions With Medication
To analyze the effects of different exercise training modalities (continuous, intervallic, and resistance training) on cardiorespiratory and metabolic fitness of metabolic syndrome patients when this training interacts with their…
- Conditions
- Exercise Therapy, Metabolic Syndrome X, Cardiorespiratory Fitness
- Trial name
- METSYND (NCT03019796)
- Testing
- MEDICATION AND EXERCISE TRAINING
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- University of Castilla-La Mancha
Health Behavior, Physical Activity
Predictors of Increased Physical Activity in Patients Receiving Physical Activity on Prescription
The aim of this study is to explore possible predicting factors associated with physical activity (PA) level change in a 6-month period of physical activity on prescription (PAP) treatment.
- Conditions
- Health Behavior, Physical Activity, Metabolic Syndrome X, Primary Health Care
- Trial name
- NCT03586011
- Testing
- Predicting factors for increased physical activity
- Where
- Sweden
- Volunteers
- 444 people
- Sponsor
- Vastra Gotaland Region
Metabolic Syndrome X
Effects of TA-65, a Telomerase Activator on Metabolic Syndrome
This study is being conducted to evaluate the efficacy of TA-65, a purified extract of Astragalus root, on insulin resistance, oxidative stress, and inflammation in individuals classified with metabolic syndrome.
- Trial name
- NCT02531334
- Testing
- TA-65
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Connecticut
Sleep Apnea Syndromes, Snoring
Effects From a Mandibular Repositioning Appliance in Patients With Obstructive Sleep Apnea and Snoring
The purpose of this study is to evaluate effects from a mandibular repositioning appliance on obstructive sleep apneas, symptoms, blood pressure and markers of stress, inflammation and cardiovascular health in patients with mild…
- Conditions
- Sleep Apnea Syndromes, Snoring, Disorders of Excessive Somnolence
- Trial name
- NCT00477009
- Testing
- Mandibular repositioning appliance, adjustable
- Where
- Sweden
- Volunteers
- 96 people
- Sponsor
- Umeå University
Hyperlipidemia, Metabolic Syndrome X
Low Fat Plant-Based Supplemented Diet Effects on Risk Factors for Chronic Non-communicable Diseases
The effect of a diet free from animal-sourced nutrients on a variety of risk factors for chronic non-communicable diseases in weight reduction programs is not well established.
- Trial name
- LFPBDS2 (NCT02905448)
- Testing
- Low fat plant-based nutrition
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Barbara Jakše s.p.
Polycystic Ovary Syndrome
Effects of Metformin and Oral Hormonal Contraceptive in Adolescents With Polycystic Ovary Syndrome
The polycystic ovary syndrome is the most common endocrinopathy in reproductive age women. The pathophysiology of this syndrome remains unclear, but there are evidences that a decreased in insulin sensitivity may be related in…
- Trial name
- NCT00988078
- Testing
- Metformin
- Where
- Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Metabolic Syndrome X
Sympathetic Activity in Individuals With the Metabolic Syndrome: Benefits of Lifestyle Interventions
An abdominal distribution of fat is associated with the greatest heart disease risk, because commonly, several risk factors of metabolic origin (high blood pressure, unfavourable cholesterol profile, elevated blood sugar…
- Trial name
- NCT00163943
- Testing
- Dietary weight loss +/- aerobic exercise
- Where
- Australia
- Volunteers
- 66 people
- Sponsor
- Bayside Health
Metabolic Syndrome X
Effect of Ursolic Acid Administration on Insulin Sensitivity and Metabolic Syndrome
The metabolic syndrome is characterized by the presence of overweight/obesity, insulin resistance, hyperglycemia, dyslipidaemia and hypertension and an inflammatory state, which together increase the risk of developing…
- Trial name
- NCT02337933
- Testing
- Ursolic acid
- Where
- Mexico
- Volunteers
- 24 people
- Sponsor
- University of Guadalajara
Tinnitus, Metabolic Syndrome X
Lifestyle Changes in Older Adults With Metabolic Syndrome and Tinnitus
The problem of tinnitus (subjective type) is prevalent in obese older adults with different diseases such as metabolic syndrome. The changes of lifestyle are very important to lose weight, improve tinnitus and metabolic syndrome
- Conditions
- Tinnitus, Metabolic Syndrome X, Obesity, Elderly
- Trial name
- NCT06702085
- Testing
- Lifestyle Management
- Where
- 2 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Metabolic Syndrome X, Insulin Resistance
Study of Niacin and Rosiglitazone in Dysmetabolic Dyslipidemia
Lipid abnormalities in people with the Metabolic Syndrome (the Insulin Resistance Syndrome) are characterized by elevations in triglycerides and LDL cholesterol; low levels of HDL cholesterol; and small, dense LDL particles.
- Trial name
- NCT00304993
- Testing
- fenofibrate, niacin, rosiglitazone
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Foundation Research, Florida
Metabolic Syndrome X, Cardiovascular Problems in Elderly
Effect of Blood Flow Restriction on Cardiovascular Function in Elderly with Metabolic Syndrome X
The purpose of the study is to investigate the effect of aerobic exercise with Blood flow restriction training (BFR) on cardiovascular function and quality of life in hypertensive elderly patients.
- Trial name
- NCT06877130
- Testing
- Aerobic exercise with BFR, Aerobic training
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Diabetes Mellitus, Type 2, Metabolic Syndrome X
A Phase IIa Proof-of-concept Study of NC-503 in Patients With Type II Diabetes
The main objectives of the current study are to establish the safety and clinical proof-of-concept of NC-503 in inadequately controlled patients with Type 2 diabetes and features of metabolic syndrome treated with either…
- Trial name
- NCT00675857
- Testing
- NC-503 (eprodisate disodium)
- Where
- 21 sites in Canada
- Volunteers
- 200 people
- Sponsor
- Bellus Health Inc. - a GSK company
Metabolic Syndrome X
Effects of Tumor Necrosis Factor (TNF)-Alpha Antagonism in Patients With Metabolic Syndrome
Metabolic syndrome is associated with increased inflammatory cytokines and reduced adiponectin, that may be mediated in part by TNF production from abdominal fat.
- Trial name
- NCT00111956
- Testing
- Etanercept
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Metabolic Syndrome X
The Effects of Omega-3 Fatty Acids on Metabolic Syndrome
The purpose of this study is to determine the effects of omega-3 fatty acids in the form of fish oil supplementation (approximately 2 grams per day) on the carotid intima-media (CIMT)progression (primary objective) and…
- Trial name
- NCT00350194
- Testing
- Omega-3 fatty acids
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Washington
Insulin Resistance Syndrome
Effect of Konjac-mannan in Individuals With Insulin-Resistance Syndrome
To study whether a diet high in fiber from Konjac-mannan (KJM) has an effect on metabolic control in individuals with insulin resistance syndrome.
- Trial name
- NCT03741686
- Testing
- konjac glucomannan, wheat bran
- Volunteers
- 11 people
- Sponsor
- Unity Health Toronto
Metabolic Syndrome X
Environmental Triggers Of Cardiometabolic Disease
The investigators posit that a multi-national collaborative effort with focused investigations in environments with the highest levels of exposure (developing countries such as China and India), are likely to provide new and much…
- Trial name
- AIRCMD (NCT01548300)
- Where
- 3 sites in United States, China
- Volunteers
- 66 people
- Sponsor
- Sanjay Rajagopalan
Obesity, Sarcopenia
Diet and Exercise Interventions to Increase Muscle Strength and Function
The objective of this study is to test the effects of a healthy diet \& walking (Controls) compared to a healthy diet, walking, and balance/strength exercises (Intervention) on muscle density in two populations: elderly…
- Conditions
- Obesity, Sarcopenia, Metabolic Syndrome X
- Trial name
- NCT02850562
- Testing
- Walking, Walking + Exercise
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- South Dakota State University