Clinical trials: Insulin Resistance Syndrome X
Polycystic Ovary Syndrome
Effects of Metformin and Oral Hormonal Contraceptive in Adolescents With Polycystic Ovary Syndrome
The polycystic ovary syndrome is the most common endocrinopathy in reproductive age women. The pathophysiology of this syndrome remains unclear, but there are evidences that a decreased in insulin sensitivity may be related in…
- Trial name
- NCT00988078
- Testing
- Metformin
- Where
- Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Metabolic Syndrome X
High Density Lipoprotein (HDL) Functionality in Metabolic Syndrome
The aim of the study is to examine the kinetic, anti-oxidant, anti-inflammatory and cellular cholesterol efflux properties of high-density lipoprotein (HDL) in subjects with the metabolic syndrome (MetS) and lean individuals.
- Trial name
- NCT00716300
- Where
- Australia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The University of Western Australia
Cardiovascular Diseases, Metabolic Syndrome x
Impact of Interventions With a Diet and Exercise on the Cardio-metabolic Status in Multi-risk Population
The diseases derived from Metabolic Syndrome caused 75% of the total deaths. It is more profitable to invest in prevention than in the treatment of most cardiovascular diseases.
- Conditions
- Cardiovascular Diseases, Metabolic Syndrome x, Mediterranean Diet
- Trial name
- PANDEMONIO (NCT03701425)
- Testing
- Mediterranean diet and exercise plan
- Where
- Mexico
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado
Dyslipidemia, Insulin Resistance Syndrome
Prescription of Step Counts for Targeted Changes in Body Composition and Cardiometabolic Risk in Overweight/Obese Adults
The prevalence of overweight and obesity remains epidemic in the United States, with some of the highest rates seen in older adults.
- Conditions
- Dyslipidemia, Insulin Resistance Syndrome, Hypertension, Inflammation Chronic
- Trial name
- NCT07221279
- Testing
- Step counts for predictable changes in body weight/compositon and cardiometabolic risk
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kennesaw State University
Blood Pressure, Metabolic Syndrome X
Dairy Products and Metabolic Syndrome
The purpose of this trial is to investigate the effect of dairy products on the so called metabolic syndrome. Metabolic syndrome is a cluster of risk factors, such as high blood pressure and high cholesterol, for the development…
- Trial name
- NCT01913756
- Testing
- Gamalost (Norwegian traditional cheese), Gouda-type cheese
- Where
- Norway
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Life Sciences
Metabolic Syndrome X, Inflammation
Effect of Dietary Flavonoids on Intestinal Microbiota, Intestinal Inflammation and Metabolic Syndrome
The investigators have hypothesized that dietary flavonoids reduce insulin resistance and subclinical inflammation secondary to reductions in intestinal inflammation and permeability and that these events are mediated through…
- Trial name
- NCT02728570
- Testing
- High Dietary Flavonoids, Low Dietary Flavonoids
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Utah State University
Metabolic Syndrome X
Efficacy of a Prebiotic Galactooligosaccharide to Reduce Metabolic Syndrome Risk Factors in Overweight Adults
The traditional risk factors for obesity are inappropriate diet, lack of exercise and genetic factors. However, recent observations have involved gut microbiota profiles as having an additional influence.
- Trial name
- NCT01004120
- Testing
- Bimuno, Maltodextrin
- Where
- United Kingdom
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Clasado
Diabetes, Metabolic Syndrome x
Botanical Oil Supplementation in Diabetic and Metabolic Syndrome Subjects
This study will compare how well a combination of borage and echium oils will reduce inflammation compared to fish oils and placebo oil in subjects that are diabetic or have metabolic syndrome.
- Trial name
- NCT01145066
- Testing
- borage/echium oil combination, fish oil, corn oil
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Wake Forest University Health Sciences
Insulin Resistance - Type A, Insulin Resistance - Type B
A Extension Study of Empagliflozin in Patients With Refractory Diabetes Mellitus With Insulin Resistance ( EMPIRE-02 )
A multicenter, open-label, single-arm, extension study with regard to the safety and efficacy of empagliflozin in patients with refractory diabetes mellitus with insulin resistance.
- Conditions
- Insulin Resistance - Type A, Insulin Resistance - Type B, Lipoatrophic Diabetes Mellitus, Insulin Resistance Syndrome
- Trial name
- EMPIRE-02 (NCT04221152)
- Testing
- Empagliflozin Tablets
- Where
- 5 sites in Japan
- Volunteers
- 8 people
- Sponsor
- Kobe University
HIV Infections, Metabolic Syndrome X
Lifestyle Modification and Metformin Use in the Treatment of HIV
A healthy diet and exercise have improved the health of people without human immunodeficiency virus (HIV) who have Metabolic Syndrome.
- Trial name
- NCT00399360
- Testing
- Metformin, Lifestyle Modification
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Massachusetts General Hospital
Schizophrenia, Schizophrenia Spectrum and Other Psychotic Disorders
Berberine as Adjuvant Treatment for Schizophrenia Patients
One double-blind, randomized, placebo-controlled trial is designed to examine whether berberine added to current antipsychotic drugs could produce significantly greater efficacy in reducing atypical antipsychotic-induced…
- Conditions
- Schizophrenia, Schizophrenia Spectrum and Other Psychotic Disorders, Metabolic Syndrome x
- Trial name
- BER (NCT02983188)
- Testing
- Berberine, Antipsychotic Agents
- Where
- Hong Kong
- Volunteers
- 113 people
- Sponsor
- The University of Hong Kong
Metabolic Syndrome X
Effect of Irvingia Gabonensis Administration on Metabolic Syndrome, Insulin Secretion and Insulin Sensitivity
The metabolic syndrome is a high prevalence disease worldwide. About a quarter of the adult population suffers from the disease and predispose the onset of diseases like cardiovascular disease and diabetes mellitus type 2.
- Trial name
- NCT02354339
- Testing
- Irvingia gabonensis
- Where
- Mexico
- Volunteers
- 24 people
- Sponsor
- University of Guadalajara
Obesity, Metabolic Syndrome X
Weight and Metabolic Effects of an Almond Enriched Hypocaloric, Low Fat Diet on Overweight and Obese Persons
The purpose of this trial is to study the safety, tolerability and efficacy of an almond enriched hypocaloric diet on weight loss and weight maintenance, as well as on established and emerging cardiovascular risk factors in…
- Conditions
- Obesity, Metabolic Syndrome X, Hyperlipidemia, Hypertension
- Trial name
- NCT00194428
- Testing
- Almond enriched diet, Low fat caloric diet
- Where
- United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Temple University
Atherosclerosis, Congestive Heart Failure
Dallas Heart Study 2: Return Clinic Visit for the Dallas Heart Study Cohort
The Dallas Heart Study (DHS-1) is a large, multi-ethnic, population-based epidemiological study designed to identify determinants of atherosclerotic heart disease (ASHD) in a representative United States (US) urban environment.
- Conditions
- Atherosclerosis, Congestive Heart Failure, Left Ventricular Hypertrophy, Diabetes Mellitus
- Trial name
- NCT00344903
- Where
- United States
- Volunteers
- 3,400 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Metabolic Syndrome X
Flaxseed Intervention on Metabolic Syndrome
The purpose of this study is to determine whether daily supplement of 30 grams flaxseed is effective in the treatment of metabolic syndrome (MetS).
- Trial name
- FIMS (NCT00733772)
- Testing
- flaxseed, Health lifestyle counseling
- Where
- China
- Volunteers
- 189 people
- Sponsor
- Chinese Academy of Sciences
Aortic Valve Stenosis
Metabolic Determinants of the Progression of Aortic Stenosis
Calcific aortic stenosis (AS) has become the most common cardiac disease after coronary artery disease and hypertension. Unfortunately no medical therapies have been proven to decrease either the progression of valve stenosis or…
- Trial name
- PROGRESSA (NCT01679431)
- Testing
- Doppler-echocardiography, Computed tomography, Magnetic resonance imaging
- Where
- Canada
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Laval University
Metabolic Syndrome X
Efficacy Study Regarding the Beneficial Effects of Omega-3 Fatty Acids on Cardiometabolic Health
Fish oil supplements (which are rich in omega-3 fatty acids) have been shown to provide cardiometabolic benefits to individuals of all ages.
- Trial name
- FOHS (NCT02042274)
- Testing
- Fish oil supplement
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Guelph
Metabolic Syndrome X, Atherosclerosis
The Effects of Interrupting Prolonged Sitting With Intermittent Exercise on Postprandial Lipemia
The purpose of this study is to investigate the effect of interrupting prolong sedentary behavior with interval exercise on postprandial metabolism following a high fat glucose tolerance test.
- Conditions
- Metabolic Syndrome X, Atherosclerosis, Insulin Resistance, Hyperinsulinism
- Trial name
- NCT03856606
- Testing
- Prolonged sitting without exercise, Prolonged sitting with interval exercise
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Metabolic Syndrome X, Prediabetic State
Education, Counseling, and Drug Therapy to Reduce Symptoms of Metabolic Syndrome
This study will determine the effects of a supplement in reducing symptoms of metabolic syndrome, a collection of symptoms that increase the risk for developing heart disease, stroke, and diabetes.
- Conditions
- Metabolic Syndrome X, Prediabetic State, Insulin Resistance, Obesity
- Trial name
- NCT00129792
- Testing
- Dietary supplement for weight loss, Education and counseling for weight loss
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Oregon Health and Science University
Metabolic Syndrome X
Environmental Triggers Of Cardiometabolic Disease
The investigators posit that a multi-national collaborative effort with focused investigations in environments with the highest levels of exposure (developing countries such as China and India), are likely to provide new and much…
- Trial name
- AIRCMD (NCT01548300)
- Where
- 3 sites in United States, China
- Volunteers
- 66 people
- Sponsor
- Sanjay Rajagopalan