Clinical trials: Insulin Resistance Syndrome X
Healthy, Metabolic Syndrome X
Investigation of Genetic Risk of Metabolic Syndrome in Company Employee (NGK Study)
The metabolic syndrome is a highly prevalent disorder, which causes atherosclerotic cardiovascular disease and is closely associated with insulin resistance.
- Conditions
- Healthy, Metabolic Syndrome X, Hyperlipidemia, Hypertension
- Trial name
- NCT00408824
- Where
- Japan
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Nagoya University
Insulin Resistance Syndrome
Diagnostic Interest of the IRAP Protein (Insulin Regulated Amino Peptidase) in Insulin Resistance
There is currently no reliable, diagnostic tests of insulin resistance other than the hyperinsulinemic euglycemic clamp which, due to its constraints and cost, is reserved for research.
- Trial name
- IRAP-IR (NCT04028895)
- Testing
- Dosage of IRAP during OGTT
- Where
- 4 sites in France
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Overweight, Metabolic Syndrome X
Health of Young European Families and Fish Consumption
This is a controlled, randomized, intervention trial (CRIT) with 20-40 year old overweight individuals (n = 320) across Europe in order to distinguish between biologically active components of seafood, i.e., seafood proteins and…
- Conditions
- Overweight, Metabolic Syndrome X, Bone Resorption
- Trial name
- NCT00315770
- Testing
- weight loss diets for young adults
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Landspitali University Hospital
Insulin Resistance Syndrome X, Pancreatic Beta Cell Function
Mechanism of Fatty Acid-Induced Impairment of Glucose-Stimulated Insulin Secretion
A prolonged elevation of plasma free fatty acids (FFA) impairs glucose stimulated insulin secretion. The concept of fatty acid impairment of glucose stimulated insulin secretion (lipotoxicity) has now been well accepted.
- Trial name
- NCT00188773
- Testing
- N-acetylcysteine, intralipid, heparin
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Metabolic Syndrome X, Nutritional and Metabolic Diseases
Nutrition and Lifestyle Behaviour Peer Support Program Among Malaysian Adults With Metabolic Syndrome (PERSUADE)
The outlook of a community-based intervention targeting nutrition and lifestyle behaviour modification among adults with metabolic syndrome (MetS) has not been fully explored.
- Conditions
- Metabolic Syndrome X, Nutritional and Metabolic Diseases, Health Behavior
- Trial name
- PERSUADE (NCT03417128)
- Testing
- Peer support
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Monash University
Carotid Artery Plaque, Arteriosclerosis
Atherosclerosis Underlying Development Assessed by Intima-Media Thickness in Patients on Rimonabant
Objectives: Primary: To evaluate the effect of rimonabant 20-mg once daily in comparison with placebo, on the quantitative progression of atherosclerosis as assessed by carotid artery intima-media thickness (CIMT) Secondary: To…
- Conditions
- Carotid Artery Plaque, Arteriosclerosis, Obesity, Metabolic Syndrome X
- Trial name
- AUDITOR (NCT00228176)
- Testing
- Rimonabant
- Where
- 6 sites in United States, Canada and 4 more
- Volunteers
- 661 people
- Sponsor
- Sanofi
Metabolic Syndrome X
Inflammation and the Metabolic Syndrome in Humans
People who are overweight are at increased risk of heart disease. Being overweight and having heart disease are linked in that both involve inflammation.
- Trial name
- LPS (NCT00954824)
- Testing
- Endotoxin (LPS)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Metabolic Syndrome X, Diastolic Dysfunction
Metformin in the Diastolic Dysfunction of Metabolic Syndrome
Metabolic syndrome (MS) is a cluster of risk factors for cardiovascular disease with increasing prevalence worldwide and insulin resistance is central to its pathophysiology and multi-organ deleterious effects.
- Conditions
- Metabolic Syndrome X, Diastolic Dysfunction, Insulin Resistance
- Trial name
- MET-DIME (NCT02017561)
- Testing
- Lifestyle Counseling, Metformin
- Where
- Portugal
- Volunteers
- 54 people
- Sponsor
- Universidade do Porto
Diabetes Mellitus Type 2, Mild Cognitive Impairment
The Early Warning System for the Diabetic Encephalopathy
Diabetes( mainly type II diabetes )lead to the central nervous system (CNS) function impairment, especially the mild cognitive impairment that increased the risk of progression to dementia.The primary objectives are defined…
- Conditions
- Diabetes Mellitus Type 2, Mild Cognitive Impairment, Metabolic Syndrome X
- Trial name
- NCT02420470
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Tang-Du Hospital
Psychotic Disorders, Metabolic Syndrome x
Is Health Coaching Effective for Improving Metabolic Health in People With Psychosis Disorders?
Antipsychotic medications frequently cause metabolic side-effects, such as abdominal obesity, high blood pressure, cholesterol abnormalities, and blood sugar dysregulation, all of which can lead to what is known as the Metabolic…
- Trial name
- NCT01752465
- Testing
- Health Coaching, Standard care
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of British Columbia
Metabolic Syndrome X
The Effects of Omega-3 Fatty Acids on Metabolic Syndrome
The purpose of this study is to determine the effects of omega-3 fatty acids in the form of fish oil supplementation (approximately 2 grams per day) on the carotid intima-media (CIMT)progression (primary objective) and…
- Trial name
- NCT00350194
- Testing
- Omega-3 fatty acids
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Washington
Metabolic Syndrome X
EFFECT OF Salvia Hispanica l. (CHIA) IN THE BIOCHEMICAL METABOLIC SYNDROME COMPONENTS
The objective of this study is to evaluate the effect of the administration of 25 g of chia per day, for 90 days on the biochemical components of the metabolic syndrome in subjects with this condition
- Trial name
- NCT02480673
- Testing
- Chia, Oatmeal, Normocaloric diet
- Where
- Mexico
- Volunteers
- 100 people
- Sponsor
- Instituto Mexicano del Seguro Social
Metabolic Syndrome X
Telmisartan-Induced Reduction in Intra-Myocellular Lipids Trial
The purpose of this study is to determine whether telmisartan and/or a low-glycemic index diet are effective in reducing intra-myocellular lipid (muscle fat) content.
- Trial name
- NCT00147264
- Testing
- Low-Glycemic Index Diet vs. Control Diet
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- McMaster University
Metabolic Syndrome X, Down Syndrome
Frequency of Metabolic Syndrome in Down Syndrome Patients
The aim of this study is to assess the frequency of metabolic syndrome in Down syndrome patients because the prevalence of diabetes mellitus and obesity is higher in individuals with Down syndrome than in the general population.
- Trial name
- NCT00864461
- Where
- Mexico
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Universidad de Guanajuato
Insulin Resistance, Metabolic Syndrome X
The Health Effects of Blueberry Anthocyanins in Metabolic Syndrome (the CIRCLES-study)
The purpose of this study is to determine the dose-dependent impact of 6 month freeze-dried blueberry powder intake on insulin sensitivity and resistance, cardiovascular disease risk factors, and lung and cognitive function in…
- Trial name
- CIRCLES (NCT02035592)
- Testing
- Full dose blueberry, Half dose blueberry, Control
- Where
- 4 sites in United States, United Kingdom
- Volunteers
- 144 people
- Sponsor
- University of East Anglia
Exercise Therapy, Metabolic Syndrome X
Exercise Training Effects on Metabolic Syndrome: Interactions With Medication
To analyze the effects of different exercise training modalities (continuous, intervallic, and resistance training) on cardiorespiratory and metabolic fitness of metabolic syndrome patients when this training interacts with their…
- Conditions
- Exercise Therapy, Metabolic Syndrome X, Cardiorespiratory Fitness
- Trial name
- METSYND (NCT03019796)
- Testing
- MEDICATION AND EXERCISE TRAINING
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- University of Castilla-La Mancha
Metabolic Syndrome X, Exercise
The Effects of High-intensity Aerobic Training in Patients With Metabolic Syndrome
Background. The prevalence of metabolic syndrome (MetS) has been increasing, and its risk is positively correlated with age. Due to ageing society in Taiwan, how to treat metabolic syndrome and decrease the complications is an…
- Conditions
- Metabolic Syndrome X, Exercise, Physical Activity
- Trial name
- NCT02130336
- Testing
- Aerobic interval training, Continuous moderate-intensity exercise
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Metabolic Syndrome X
The Metabolic Syndrome Among Leukemia Survivors: Physiopathological Analysis
Along with the improvement of childhood acute leukemia treatment, survival rates have increased. Therefore, the number of long term childhood leukemia survivors has increased progressively over the last decades.
- Trial name
- LEAMS (NCT02696304)
- Testing
- Adipose tissu repartition, Visceral and liver adipose tissue repartition, Preadipocyte quantification and adipose tissue inflamation
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Metabolic Syndrome X
Multimodal Intervention Program for Patients With Metabolic Syndrome
The aim of this study is to identify the psychological, emotional and lifestyle variables that can have an influence on the different components of metabolic syndrome (MetS) and develop a program for change lifestyle in this…
- Trial name
- PROMETS (NCT02949622)
- Testing
- Multimodal intervention program, Lifestyle counseling
- Where
- Spain
- Volunteers
- 136 people
- Sponsor
- Universidad de Granada
Dysmetabolic Iron Overload Syndrome, Metabolic Syndrome X
MEPHISTO (Macrophage Phenotype In Metabolic Syndrome With Iron Overload)
Dysmetabolic iron overload syndrome (DIOS), is a frequent hepatic iron overload associated with metabolic syndrome. We hypothesize that this mild iron overload can induce a increased macrophagic polarization towards inflammatory…
- Trial name
- MEPHISTO (NCT02066012)
- Testing
- dysmetabolic iron overload syndrome
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand