Clinical trials: Intense Exercise
Multiple Sclerosis
Multiple Sclerosis, Menstrual Cycle and Physical Acivity
This study aims to identify moderating variables that modify satisfaction with physical activity practice throughout the menstrual cycle (MC) in women with and without multiple sclerosis (MS) during High-Intensity Interval…
- Trial name
- EMMA (NCT06105463)
- Testing
- Strength training sessions and High-interval intensity training sessions
- Where
- Spain
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Universidad de Almeria
Prostate Cancer
INTERVAL - Intense Exercise Trial for Men With Metastatic Castrate-Resistant Prostate Cancer
Exercise has been established to be safe and result in improved physical function and quality of life for most individuals with cancer.
- Trial name
- INTERVAL (NCT04507698)
- Testing
- Intensive Exercise Intervention
- Where
- 4 sites in United Kingdom
- Volunteers
- 80 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
HFpEF - Heart Failure With Preserved Ejection Fraction
Cardiopulmonary Exercise Testing-based High-intensity Interval Training For Improving Heart Failure With Preserved Ejection Fraction
Cardiovascular-Kidney-Metabolic (CKM) Syndrome is a continuous clinical disease spectrum integrating cardiovascular, renal, and metabolic disorders.
- Trial name
- CPHIT-HFpEF (NCT07693049)
- Testing
- High-intensity interval training
- Where
- 13 sites in China
- Volunteers
- 192 people
- Sponsor
- Peking University Third Hospital
Weight Loss, Obese Children and Adolescents
The Therapeutic Effect of Different Exercise Intensities on Weight Loss in Obese Children
The incidence of childhood obesity is increasing, followed by metabolic diseases related to overweight and obesity in children. High intensity interval training (HIIT) has recently been shown to improve the body composition and…
- Trial name
- NCT06205563
- Testing
- high-intensity interval training, moderate intensity continuous training
- Volunteers
- 388 people
- Sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
Aging
Sex Differences in Vascular Responses to Exercise
A key early event in cardiovascular disease development is endothelial dysfunction, characterized by impaired flow-mediated dilation.
- Trial name
- NCT04128215
- Testing
- Control Period, Exercise Period
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Florida
Exercise Training Adaptation, Exercise Physiology
SPORT-SPECIFIC HIIT IN ELITE KICKBOXERS
This study examines how sport-specific high-intensity interval training (HIIT) affects the body in elite kickboxers. Participants are randomly assigned to either a HIIT training group or a control group.
- Conditions
- Exercise Training Adaptation, Exercise Physiology, High-Intensity Interval Training
- Trial name
- HIIT-KICK (NCT07449663)
- Testing
- Sport-Specific High-Intensity Interval Training, Regular Training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Adiyaman University
Parkinson Disease
BIG for Life: a Pilot Study
This research study will aim to evaluate BIG for LIFE as a group exercise program, and determine whether three time a week exercise sessions with heart rate monitoring is beneficial to maintain or improve physical function…
- Trial name
- NCT04090476
- Testing
- Exercise
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Stroke
Early Intervention With a Low-intensity Leg Cycling Exercise Program for Individuals After Stroke
This is a two-stage study. In the first stage, 30 subjects with stroke (onset > 2 weeks) are recruited, and they are assessed and recorded with clinical characteristics, sympathetic nerve testing, and twice symptom-limit exercise…
- Trial name
- NCT02437006
- Testing
- exercise
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Heart Disease, Heart Attacks
The Health Impact of High Intensity Exercise Training With Intervals During Cardiac Rehabilitation
Cardiac rehabilitation is a program designed to help patients regain good health through lifestyle change after a heart attack, heart surgery or other heart problems.
- Trial name
- NCT02376244
- Testing
- High intensity interval training (HIIT), Standard care
- Where
- United Kingdom
- Volunteers
- 34 people
- Sponsor
- Liverpool Heart and Chest Hospital NHS Foundation Trust
Melanoma (Skin), Skin Cancer
High-Intensity Exercise and High-Fiber Diet for Immunotherapy Outcomes in Melanoma Patients: The DUO Trial
The purpose of this study is to determine whether high-intensity exercise and high-fiber diet are feasible and improve various health outcomes among participants with advanced melanoma receiving immunotherapy.
- Conditions
- Melanoma (Skin), Skin Cancer, Advanced Melanoma
- Trial name
- NCT06298734
- Testing
- Exercise Program, Diet Program
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Fred Hutchinson Cancer Center
Sedentary Behavior
Short Moderate-intensity Continuous Training on Sedentary Women's
Purpose: To determine the effects of three Short Moderate Intensity Continuous Training (SMICT) exercise programs with different durations, on functional capacity, resting heart rate (RHR) and physical activity enjoyment in…
- Trial name
- NCT06242899
- Testing
- Exercise
- Where
- Spain
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Exercise-induced Myocardial Damage, Right Ventricular Diastolic Dysfunction
Effects of Exogenous Ketones on Acute Changes and Recovery of the Heart Muscle After Intense Exercise.
It is well known that scar tissue on the heart muscle can cause (life-threatening) arrhythmias. However, the exact cause of this scar tissue is not entirely clear.
- Trial name
- NCT06715748
- Testing
- Ketone Monoester (KE)
- Where
- Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Jessa Hospital
Physical Activity, Obesity, Childhood
The MOVI-HIIT Pilot Trial: The Impact of Activity Breaks on Cognitive Function, Adiposity and Fitness in Preschoolers
Pilot study to test the acceptability and feasibility of an intervention aimed to test the effectiveness, in preschool children, of an integrated physical activity intervention in the classroom based on intervallic training…
- Conditions
- Physical Activity, Obesity, Childhood, Cardiovascular Diseases, High Intensity Interval Training
- Trial name
- NCT05243784
- Testing
- MOVI-HIIT intervention
- Where
- Spain
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Prediabetes
Effects of Hourly Stair-Climbing Exercise Snacks on Metabolic and Vascular Health in Adults With Prediabetes
This study will examine whether very short bouts of stair climbing performed throughout the day can improve blood sugar control and cardiovascular health in adults with prediabetes.
- Trial name
- RISE UP (NCT07847684)
- Testing
- Hourly 3-Minute Light Walking Breaks, Hourly Stair-Climbing Exercise Snacks
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- St. Louis University
Polyneuropathies, Obesity
Effect of Exercise and Surgical Weight Loss on Polyneuropathy
The purpose of this research study is to evaluate how exercise and surgical weight loss affect how likely an individual is to develop peripheral neuropathy and other neurologic complications.
- Conditions
- Polyneuropathies, Obesity, Bariatric Surgery Candidate
- Trial name
- NCT03617185
- Testing
- High Intensity Interval Training (HIIT), Routine Exercise, Bariatric surgery
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- University of Michigan
Breast Cancer
Different Resistance Training Intensity Prescription and Monitoring Methodologies: Effects on Strength, Body Composition, and Well-being in Survivors of Breast Cancer
The goal of this clinical trial is to compare the effects of three different methods of prescribing and monitoring resistance training intensity on muscle strength, body composition, quality of life, fatigue, anxiety, and…
- Trial name
- NCT06940310
- Testing
- Daily load-velocity-based training intensity adjustment., Training intensity prescription based on an initial 1RM estimation using load-velocity relationship, Traditional training with intensity prescription based on 1RM testing.
- Where
- Spain
- Volunteers
- 61 people
- Sponsor
- Universidad de Almeria
Elderly, Pre-diabetic
The Effect of Oral Carnitine Supplementation on MRS-derived Mitochondrial Function
This is a longitudinal study supported by Pfizer and is a collaboration between DMPI (Duke Molecular Physiology Institute) and DIAL (Duke Image Acquisition Laboratory) to measure the effects of acute exercise on carnitine and…
- Trial name
- NCT02124590
- Testing
- Acute Exercise
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Duke University
Heart Rate, All-day Steps
Assessing the Effect of Cool Roofs on Health Using Smartwatches in Niue
Ambient air temperatures in the Pacific have broken record highs in 2024. Solutions are needed to build heat resilience in communities and adapt to increasing heat from climate change.
- Conditions
- Heart Rate, All-day Steps, Distance Walked, Active Minutes
- Trial name
- REFLECT (NCT06571019)
- Testing
- Cool roof
- Where
- Niue
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- Aditi Bunker
Parkinson, Parkinson Disease
The Effect of Exercise in Water on Functional Fitness in People With Parkinson's Disease
The goal of this clinical trial study is to learn about the effect of aquatic exercise in parkinson's patients. The main questions it aims to answer are: What is the effect of exercise in water on balance in parkinson's patients?…
- Conditions
- Parkinson, Parkinson Disease, Neurologic Disorder
- Trial name
- NCT05737992
- Testing
- Exercise in water
- Where
- Iran
- Volunteers
- 42 people
- Sponsor
- Pardis Specialized Wellness Institute
Obesity, Older Adults
Investigating Fitness Interventions in the Elderly (INFINITE)
Aging is associated with declines in aerobic capacity, exercise tolerance, and functional endurance that lead to physical disability and loss of independence.
- Conditions
- Obesity, Older Adults, Sedentary
- Trial name
- INFINITE (NCT01048736)
- Testing
- Exercise Only, Exercise + Diet
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences