Clinical trials: Intense Exercise, open to volunteers
Osteoporosis, Postmenopausal, Osteopenia
High-Intensity Laser Therapy and Physiotherapy for Bone Health in Postmenopausal Women: A Randomized Trial
The goal of this clinical trial is to learn if adding high-intensity laser therapy (HILT) to a physiotherapy programme helps bone health in women after menopause who have low bone density (osteopenia or osteoporosis).
- Trial name
- NCT07734922
- Testing
- High-Intensity Laser Therapy, Standardised Physiotherapy Programme
- Where
- Romania
- Volunteers
- 40 people
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Concussion, Mild Traumatic Brain Injury
Impact of a Paced Breathing Exercise Intervention on Autonomic Nervous System Function After Pediatric Concussion (Acute Phase)
The goal of this pilot clinical trial is to assess the feasibility of administering a paced breathing exercise intervention program to children and adolescents in the acute period after concussion.
- Trial name
- Breathe - PED (NCT07572734)
- Testing
- Paced breathing exercises
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Metabolic Dysfunction-Associated Fatty Liver Disease
CPET-based HIIT for MAFLD
High-intensity interval training (HIIT), as an individualized exercise training mode based on cardiopulmonary exercise testing (CPET), is characterized by high-intensity training sessions interspersed with short rest periods.
- Trial name
- CEPHIT (NCT07177963)
- Testing
- HIIT, No specific exercise intervention.
- Where
- 5 sites in China
- Volunteers
- 54 people
- Sponsor
- Tang Yida
PreDiabetes, Pre Diabetes
Comparative Effects of High-Intensity Interval Training and Continuous Endurance Training Among Prediabetic Patients
Prediabetics is a condition where blood sugar levels are normal but not yet high enough to be diagnosed as type 2 diabetes. This phase offers a crucial point for timely intervention to delay or prevent type 2 diabetes.
- Conditions
- PreDiabetes, Pre Diabetes, Prediabetic State
- Trial name
- NCT07713030
- Testing
- High-Intensity Interval Training, Continuous Endurance Training
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Frozen Shoulder
Comparing HILT, Steroid Injection, and Manual Therapy for Frozen Shoulder
This study compares three common treatments for frozen shoulder when added to a standard exercise program: High-Intensity Laser Therapy (HILT), a corticosteroid (steroid) injection into the shoulder joint, and hands-on manual…
- Trial name
- NCT06916650
- Testing
- High-Intensity Laser Therapy (HILT), Ultrasound-Guided Intra-articular Corticosteroid Injection, Manual Therapy
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Al Hayah University In Cairo
Polycystic Ovarian Syndrome (PCOS), Quality of Life
High Intensity Interval Training Versus Mat Pilates in Women With PCOS
Polycystic Ovary Syndrome (PCOS) is a common endocrine disorder affecting women of reproductive age and is associated with obesity, insulin resistance, poor physical fitness, and reduced quality of life.
- Conditions
- Polycystic Ovarian Syndrome (PCOS), Quality of Life, Physical Fitness
- Trial name
- NCT07875400
- Testing
- High-Intensity Interval Training (HIIT), Mat Pilates group, General mobility exercises
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Riphah International University
Cancer Survivors
C.A.P.A.B.L.E. (CrossFit® and Physical Activity: A Better Life Experience)
This study will introduce cancer survivors to cross-training with the expectation that the program proposed will ultimately result in superior improvements in functional performance, body composition and quality of life compared…
- Trial name
- CAPABLE (NCT03750981)
- Testing
- 12 week pilot intervention study.
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Barbara Ann Karmanos Cancer Institute
Pediatric Brain Tumor
High-Intensity Interval Exercise in Young Adult Survivors of Pediatric Brain Tumors: A Pilot Feasibility Study
The purpose of this study is to determine whether a 16-week virtual, home-based, high-intensity interval training (HIIT) exercise program will improve physical, cognitive, and emotional health among young adult survivors of…
- Trial name
- HYPE (NCT05740839)
- Testing
- HIIT Exercise Program, Control Group
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Type 2 Diabetes Mellitus (T2DM)
Effect of Tai Chi Versus Moderate-intensity Combined Exercise Training on Cardiovascular Health and Physical Functional Performance in Older Men and Women With T2DM: the Tai Chi Intervention for Diabetes Management During Aging (TIDA) Study
This randomized, single-blind, controlled clinical trial compares the effects of a 12-week Tai Chi program versus moderate-intensity combined exercise (MICE) training on cardiovascular health, glycemic control, and physical…
- Trial name
- TIDA (NCT07131761)
- Testing
- Tai chi, Moderate-Intensity Combined Exercise (MICE), Control ( No Exercise )
- Volunteers
- 66 people
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Acute Exercise, Breast Cancer Cell Lines
Tumour Cell Response to Acute Aerobic Exercise in Breast Cancer Survivors: Modulatory Effects of Exercise Type and Intensity
Cancer has emerged as a prominent cause of mortality in the 21st century, with breast cancer (BC) being the most diagnosed malignancy.
- Conditions
- Acute Exercise, Breast Cancer Cell Lines, Breast Cancer Survivors, Healthy Women
- Trial name
- TCReX (NCT07439458)
- Testing
- High intensity continuous exercise, Moderate intensity continuous exercise
- Where
- Latvia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Riga Stradins University
Female Stress Urinary Incontinence
Extracorporeal Shock Wave Therapy to Kegel's Exercise in Management of Female Stress Urinary
Stress urinary incontinence (SUI) is a common pelvic floor disorder among women, especially those with a history of childbirth, aging, or pelvic surgery.
- Trial name
- NCT07663968
- Testing
- low-intensity extracorporeal shock (LiESWT), Kegel's exercises (KE)
- Volunteers
- 84 people
- Sponsor
- Suez Canal University
Polycystic Ovarian Syndrome (PCOS), Pittsburg Sleep Quality Index
Diaphragmatic Breathing Exercises on Sleep Disorders un Polycystic Ovarian Syndrome
Polycystic ovarian syndrome (PCOS) is the most common endocrine disorder in females in reproductive age and not completely understood. Women with PCOS appear to have an increased frequency of sleep problems.
- Conditions
- Polycystic Ovarian Syndrome (PCOS), Pittsburg Sleep Quality Index, Fatigue Severity Scale, Insomnia Severity Index
- Trial name
- NCT07698925
- Testing
- Diaphragmatic breathing exercises, Lifestyle modification advices
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- Adly A Adam
Overweight (BMI > 25), Obesity
Redox Status and Exercise Training-induced Adaptations
Excess fat accumulation is a key feature of overweight and obesity that is mainly driven by nutrient overload and insufficient physical activity.
- Trial name
- NCT07196852
- Testing
- N Acetyl L Cysteine
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Chronic Kidney Disease
Analysis of Effects of High-intensity Physical Exercise in Subjects With Dialyzed Chronic Kidney Disease and in Conservative Treatment
This study aims to analyze the effects of physical activity in patients with chronic kidney disease undergoing dialysis or conservative treatment.
- Trial name
- TONE (NCT07438002)
- Testing
- Exercise, control
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Casa di Cura Dott. Pederzoli
Lupus Erythematosus, Systemic
Effects of High-intensity Interval Training in Patients With Systemic Lupus Erythematosus
The aim of this study is to evaluate the safety and effects of high-intensity interval training (HIIT) combined with resistance training in patients with systemic lupus erythematosus
- Trial name
- SLE-HIIT (NCT06166199)
- Testing
- HIIT combined with resistance training
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Karolinska Institutet
Peripheral Neuropathy
Effect of Hands and Feet Exercises on Taxane Based Chemotherapy Induced Peripheral Neuropathy in Patients With Solid Tumors
The goal of this clinical trial is to determine whether hand and foot exercises can reduce the severity of Taxane-based chemotherapy-induced peripheral neuropathy (CIPN) in adult cancer patients aged 20-60 years who have Grade 1I…
- Trial name
- NCT07321236
- Testing
- Structured Hand and Foot Exercises
- Volunteers
- 58 people
- Sponsor
- University of Health Sciences Lahore
End Stage Renal Disease
CoQ10 and Exercise for Mitochondrial Dysfunction in Advance Kidney Disease
Frailty and sarcopenia are modifiable risk factors for morbidity and mortality in patients with ESRD. Exercise is the recommended intervention to prevent frailty and sarcopenia, however, many clinical trials have shown limited…
- Trial name
- NCT05422534
- Testing
- CoQ10, HB-HIIT, Observational
- Where
- 2 sites in United States
- Volunteers
- 156 people
- Sponsor
- Vanderbilt University Medical Center
Chronic Obstructive Pulmonary Disease (COPD)
HIIT Versus MICT in COPD: Effects on Oxygenation, Pulmonary Function, and Strength
Chronic Obstructive Pulmonary Disease (COPD) is a progressive condition marked by airflow limitation and chronic inflammation, leading to reduced exercise capacity, peripheral muscle dysfunction, and dyspnea.
- Trial name
- NCT07109687
- Testing
- HIIT GROUP, MICT
- Volunteers
- 40 people
- Sponsor
- Aynur Demirel
Frail Elderly
High Intensity Interval Training Versus Moderate Intensity Continuous Training in Frail Elderly
The assessment and systematic integration of physical activity into the care pathway of frail elderly people is essential to prevent loss of independence and improve the quality of life of this population.
- Trial name
- EPAF (NCT07211334)
- Testing
- Exercise Training
- Where
- France
- Volunteers
- 92 people
- Sponsor
- University Hospital, Grenoble
Coronary Artery Disease
A Physical Activity Programme Focussed on Step Volume and Intensity for People With Cardiovascular Disease: Getting Active and Staying Active After Cardiac Rehabilitation
The goal of this clinical trial is to learn about the effect of a physical activity program, focussing on increasing step volume and step intensity (STEP COACH program), compared to usual care in patients with coronary heart…
- Trial name
- STEP COACH RCT (NCT07723274)
- Testing
- STEP COACH intervention group
- Where
- 4 sites in Netherlands
- Volunteers
- 334 people
- Sponsor
- Radboud University Medical Center