Clinical trials: Intensity-modulated Radiotherapy
Breast Carcinoma
Trial Comparing Prone and Supine Intensity-modulated Radiotherapy (IMRT) After Breast-conserving Surgery in Patients With Large Breast Volume at High Risk for Skin Toxicity and Fibrosis
84 patients with a cup size C or more will be randomized to receive intensity-modulated radiotherapy in supine or prone position.
- Trial name
- NCT00887523
- Testing
- radiation in prone position, radiation in supine position
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- University Hospital, Ghent
Prostate Cancer
AASUR in High Risk Prostate Cancer
The purpose of this study is to determine whether anti-testosterone medications, when administered before, during, and after high-dose, precision radiation, will be effective in preventing the prostate cancer from returning.
- Trial name
- NCT02772588
- Testing
- ARN-509, Abiraterone, Leuprolide
- Where
- 11 sites in United States
- Volunteers
- 64 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Locally Advanced Cervical Cancer
Preoperative Chemoradiotherapy Combined With Nimotuzumab for Cervical Cancer
The purpose of this study is to determine the feasibility and efficacy of preoperative nimotuzumab injection combined with concurrent chemoradiotherapy for initially inoperable, locally advanced cervical cancer.
- Trial name
- NCT01938105
- Testing
- Nimotuzumab+chemoradiotherapy
- Where
- China
- Volunteers
- 40 people
- Sponsor
- People's Hospital of Guangxi Zhuang Autonomous Region
Neoplasm Metastasis
Using Intensity Modulated Radiation Therapy (IMRT) for Brain Metastases
The purpose of this study is to determine if using intensity modulated radiation therapy for brain metastases is safe and will improve local control more than standard whole brain radiation therapy.
- Trial name
- NCT00328575
- Testing
- Intensity-Modulated Radiotherapy (IMRT)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Colorectal Cancer Metastatic, Chemotherapy
Oral Chemotherapy, Targeted Therapy and Immunotherapy With/Without Radiotherapy as 3rd- or Later-line Therapy for Advanced MSS/pMMR Colorectal Cancer
The current phase 2, double cohort clinical trial was designed to determine the effectiveness of Trifluridine and Tipiracil Hydrochloride Tablets, Bevacizumab and Sintilimab with/without involved lesions irradiation as 3rd- or…
- Conditions
- Colorectal Cancer Metastatic, Chemotherapy, Targeted Therapy, Immunotherapy
- Trial name
- NCT06764680
- Testing
- Trifluorouracil tepidopyrimidine, Bevacizumab, Sindilizumab
- Where
- China
- Volunteers
- 57 people
- Sponsor
- Sun Yat-sen University
Lung Non-Small Cell Carcinoma
A Study of Targeted Post-Surgery Radiation Therapy for Non-Small Cell Lung Cancer With Remaining Lymph Node Cancer After Treatment
This phase II trial compares the effect of intensity-modulated post-operative radiation therapy (I²-PORT) followed by standard of care therapy (chemotherapy or immunotherapy) to standard of care therapy alone in treating patients…
- Trial name
- NCT07293247
- Testing
- Chemotherapy, Immunotherapy, Intensity-Modulated Radiation Therapy
- Where
- 111 sites in United States
- Volunteers
- 164 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Head and Neck Cancer, Radiation Toxicity
Radiation Therapy in Treating Patients With Stage II or Stage III Oropharyngeal Cancer
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. PURPOSE: Phase I/II trial to study the effectiveness of radiation therapy in treating patients who have stage II or stage III oropharyngeal cancer.
- Trial name
- NCT00006360
- Testing
- radioprotection, radiation therapy
- Where
- 18 sites in United States, Canada
- Sponsor
- Radiation Therapy Oncology Group
Esophagus Cancer, Esophagogastric Junction Cancer
Phase II/III Study Comparing Chemoradiotherapy With Radiotherapy in Elderly Patients With Esophageal or Esophagogastric Cancer - 3JECROG P-01
Ratiotherapy alone is the current standard treatment for elderly esophageal or esophagogastric cancer in China. And Little is known about chemoradiotherapy (CRT) in elderly patients.
- Conditions
- Esophagus Cancer, Esophagogastric Junction Cancer, Radiotherapy; Complications, Chemoradiation
- Trial name
- NCT02979691
- Testing
- SIB-IMRT, S-1
- Where
- China
- Volunteers
- 350 people
- Sponsor
- Chinese Academy of Medical Sciences
Head and Neck Neoplasms, Swallowing Sparing IMRT
The SWOAR Trial Sparing of Swallowing and Aspiration Related Organs at Risk & Submandibular Gland With Intensity Modulated Radiotherapy Versus Standard IMRT in Head and Neck Squamous Cell Carcinomas
The aim of SWOAR TRIAL is to test sparing of Dysphagia/ Aspiration risk structures (DARS) and contra lateral submandibular gland by IMRT.
- Trial name
- SWOAR (NCT05187091)
- Testing
- Swallowing and submandibular sparing IMRT, Standard IMRT with medical CRT/RT, Cisplatine
- Where
- India
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- All India Institute of Medical Sciences
Cervical Cancer, Endometrial Cancer
Intensity-Modulated Radiation Therapy to the Pelvis With or Without Chemotherapy in Treating Patients With Endometrial Cancer or Cervical Cancer That Has Been Removed By Surgery
RATIONALE: Specialized radiation therapy (RT), such as intensity-modulated radiation therapy (IMRT), that delivers a high dose of radiation directly to the tumor may kill more tumor cells and cause less damage to normal tissue.
- Trial name
- NCT00331760
- Testing
- cisplatin, intensity-modulated radiation therapy
- Where
- 153 sites in United States, Canada
- Volunteers
- 106 people
- Sponsor
- Radiation Therapy Oncology Group
Prostate Cancer
Clinical Trial Comparing 3-D RT vs. IMRT in Post- Prostatectomy Prostate Cancer Patients
Compare the incidence of acute rectal, bladder and other acute toxicities between 3-D Conformal Radiation Therapy (RT/CRT) and Intensity Modulated Radiation Therapy (IMRT) in Post-Prostatectomy Prostate Cancer Patients treated…
- Trial name
- NCT02678520
- Testing
- 3-D Conformal Radiation Therapy, Intensity Modulated Radiation Therapy, Casodex, Zoladex , Lupron
- Where
- United States
- Sponsor
- University of Kansas Medical Center
Glioblastoma
Neoadjuvant Temozolomide Combined With Simultaneous IMRT for Treatment of Glioblastoma
This study is a prospective, multi-center, randomized controlled clinical study. Indications: Glioblastoma diagnosed after surgery (WHO grade IV).
- Trial name
- NCT04829097
- Testing
- Temozolomide
- Where
- China
- Volunteers
- 80 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Prostatic Neoplasms
Hypofractionated Intensity Modulated and Image Guided Radiotherapy for Localized Prostate Cancer
Hypofractionated intensity modulated and image guided radiotherapy (HypoIGRT) with fewer high-fraction-size treatments would be beneficial for prostate cancer because it would deliver a larger biological-equivalent dose to the…
- Trial name
- NCT02651896
- Testing
- HypoIGRT
- Where
- 2 sites in Brazil
- Volunteers
- 130 people
- Sponsor
- Hospital Sirio-Libanes