Clinical trials: Intensive Behavior Management
Substance Use, Mental Health
Project Uplift: Substance Use and Mental Health Treatment for Young Sexual and Gender Minorities
This study provides substance use and mental health treatment for young sexual and gender minority adults in Durham and Charlotte, NC and seeks to provide intensive wraparound services that address factors that influence…
- Trial name
- NCT04546061
- Testing
- Project Uplift
- Where
- 2 sites in United States
- Volunteers
- 112 people
- Sponsor
- Duke University
Smoking, Mechanical Ventilation
Effect of Daily Nicotine Patch Application on Mechanical Ventilation Weaning in Smoking Patients
Nicotine patches are frequently used in smoking patients during their stay in the ICU in order to avoid tobacco's weaning symptoms which are likely to interfere with mechanical ventilation weaning.
- Conditions
- Smoking, Mechanical Ventilation, Intensive Care
- Trial name
- NICOREA (NCT01104896)
- Testing
- Nicotine patch
- Where
- France
- Volunteers
- 600 people
- Sponsor
- University of Paris 5 - Rene Descartes
Suicidal Ideation, Mental Health Issue
Intensive Case Management Between VA and Community Care for Suicide Prevention
The goal of this randomized clinical trial is to build the evidence base for SUPERCEDE, a suicide prevention focused intensive case management intervention to increase access, improve care coordination, provide suicide prevention…
- Conditions
- Suicidal Ideation, Mental Health Issue, Social Determinants of Health
- Trial name
- SUPERCEDERCT (NCT07534358)
- Testing
- SUicidE PRevention intensive CasE management and coorDination in Community CarE (SUPERCEDE), Present centered therapy
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- VA Eastern Colorado Health Care System
Type 1 Diabetes, Exercise
Exercise-induced Glycemic Variations and Hybrid Closed-loop Systems
Type 1 diabetes is characterized by high risk of hypoglycemia and associated fear of hypoglycemia. Hypoglycemia risk is higher during and after physical activity, especially aerobic activity of long duration.
- Trial name
- SAFE-T1D (NCT05736263)
- Testing
- Moderate intensity exercise, High intensity interval exercise, Combined exercise
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- University of Roma La Sapienza
Delirium, Agitation
Haloperidol vs Olanzapine for the Management of ICU Delirium
The purpose of this randomized clinical trial is to determine whether haloperidol is superior to olanzapine for the treatment of ICU acquired delirium.
- Trial name
- NCT00833300
- Testing
- Haloperidol, Olanzapine
- Where
- 2 sites in Canada
- Volunteers
- 200 people
- Sponsor
- Richard Hall
Psychological Distress, Stress, Psychological
The Effect of Psychoeducation Based on NSM on the Psychological Distress and Coping of the Spouses of Patients in ICU
The aim of action research this study is to examine the effect of psychoeducation based on Neuman's Systems Model on psychological distress and coping with the stress of spouses of patients in the intensive care unit.
- Trial name
- NCT06243523
- Testing
- The stress management psychoeducation program based on Neuman's Systems Model
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Suicide
Veterans Coordinated Community Care (3C) Study
Veterans Coordinated Community Care (3C) Study will recruit 850 Veterans at risk for suicide post inpatient hospitalization. Each participant will be randomly assigned to treatment as usual (TAU) or TAU plus the Coping Long Term…
- Trial name
- 3C (NCT05272176)
- Testing
- Coping Long Term with Active Suicide Program (CLASP)
- Where
- 7 sites in United States
- Volunteers
- 850 people
- Sponsor
- Brown University
Infant Pain Management, Parent-driven Pain Management
Parents as Pain Management in Swedish Neonatal Care
Parents are a valuable but underused resource in neonatal pain management. In the Nordic countries, family-centred neonatal care has come a long way in welcoming and including parents in the everyday care of their infant.
- Trial name
- NCT04341194
- Testing
- Parent-driven pain management with skin-to-skin contact, Parent-driven pain management with skin-to-skin contact/breastfeeding/parental singing
- Where
- 4 sites in Sweden
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Värmland County Council, Sweden
Weight Management, Obesity Prevention
Advancing Biopsychosocial Care Training Initiative
This project will compare two training approaches for US Preventive Services Task Force recommended obesity care in Federally Qualified Health Centers (FQHC) across four aims.
- Conditions
- Weight Management, Obesity Prevention, Obesity and Obesity-related Medical Conditions, Obesity and Overweight
- Trial name
- ABC Initiative (NCT07049861)
- Testing
- Comprehensive Multidisciplinary Obesity Care, Implementation as Usual Control
- Where
- United States
- Volunteers
- 6,200 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Pupillometry, Behavioral Pain Scale
Pupillometry vs. BPS (Behavioral Pain Scale) for Analgesia Management in Inpatient Intensive Care Unit Patients on Invasive Mechanical Ventilation
Patients admitted to the intensive care unit (ICU) and receiving invasive mechanical ventilation (IMV) frequently require sedation and analgesia to ensure their comfort, prevent pain associated with invasive procedures, and…
- Conditions
- Pupillometry, Behavioral Pain Scale, Analgesia Assessment, Intensive Care Unit (ICU)
- Trial name
- GOLDEN EYE (NCT07867678)
- Testing
- PPI Measurement (Pupillary Pain Index), BPS Measurement (Behavioral Pain Scale)
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Postintensive Care Syndrome, Family Members
Family Support Intervention in Intensive Care Units
Background: Family members of critically ill patients face considerable uncertainty and distress during their close other's intensive care unit (ICU) stay, with about 20-60% of family members experiencing post-traumatic distress…
- Conditions
- Postintensive Care Syndrome, Family Members, Quality of Life, Depression, Anxiety
- Trial name
- FICUS (NCT05280691)
- Testing
- Family Support Intervention (FSI)
- Where
- 12 sites in Switzerland
- Volunteers
- 885 people
- Sponsor
- Rahel Naef
Premature Infant Disease, Family Research
PREEMIE PROGRESS: A Family Management Program for Parents of Preterm Infants
The purpose of this study is to refine and pilot test a mobile health (mHealth), video-based family management program for parents of preterm infants hospitalized in the Neonatal Intensive Care Unit (NICU).
- Conditions
- Premature Infant Disease, Family Research, Parent-Child Relations, Self Efficacy
- Trial name
- NCT04638127
- Testing
- PREEMIE PROGRESS, Attention Control
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Subarachnoid Hemorrhage (SAH)
ICP Versus Intracranial Compliance Guided Management in SAH
The purpose of this study is to determine whether treatment guided also by ICP mean wave amplitude improves outcome compared to international standard care in patients with SAH.
- Trial name
- NCT00248690
- Testing
- ICP mean wave amplitude
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Oslo University Hospital
Traumatic Brain Injury, Delirium
Comparison of Haloperidol and Dexmedetomidine for Delirium and Agitation in ICU Patients With Traumatic Brain Injury
Traumatic brain injury is a serious and common medical condition that often requires admission to the intensive care unit and the use of mechanical ventilation.
- Conditions
- Traumatic Brain Injury, Delirium, Agitation
- Trial name
- NCT06993194
- Testing
- Haloperidol, Dexmedetomidine
- Volunteers
- 40 people
- Sponsor
- Benha University
Spinal Cord Injuries, Polytrauma
Conditioning & Open-Label Placebo (COLP) for Opioid Management in Intensive Inpatient Rehabilitation
The use of the conditioning open-label placebo (COLP) paradigm will be studied as a dose extension method to lower opioid dosage in patients with spinal cord injury, polytrauma, and burn injury.
- Conditions
- Spinal Cord Injuries, Polytrauma, Burns
- Trial name
- NCT05351333
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Spaulding Rehabilitation Hospital
Intensive Care Unit Syndrome, Critical Illness
Effectiveness of Stress Management Training in Reducing Caregiver Burden and Perceived Stress in ICU Families
This research helps to close an important gap in the provision of care to ICU families and introduces a structured and accessible psychological intervention to family caregivers of long-stay ICU patients.
- Trial name
- NCT07812376
- Testing
- Stress Management Training Program
- Volunteers
- 50 people
- Sponsor
- Al-Balqa Applied University
Musculoskeletal Disorders
Active Prevention of Upper Limb Musculoskeletal Disorders in Thermal Environment (MUSKA).
The main objective of this work is to demonstrate superiority to three months of a standardized short course of SPA Therapy of 6 days associated with personalized health education program compared to conventional therapy in the…
- Trial name
- MUSKA (NCT02702466)
- Testing
- SPA Therapy
- Where
- 5 sites in France
- Volunteers
- 150 people
- Sponsor
- Association Francaise pour la Recherche Thermale
Patient Reported Outcomes, Patient Satisfaction
Patient-reported Outcome and Patient-reported Experience After Status Epilepticus
Status epilepticus (SE) is a common life-threatening neurological emergency in which prolonged or multiple closely spaced seizures can result in long-term impairments.
- Conditions
- Patient Reported Outcomes, Patient Satisfaction, Long Term Outcomes, Status Epilepticus
- Trial name
- POSEIDON2 (NCT06100978)
- Where
- 19 sites in France
- Volunteers
- 145 people
- Sponsor
- Versailles Hospital
Overweight, Obesity
The Weight-Wise Weight Loss Translation Study
The overall goal of the translational research is to evaluate the processes and outcomes of implementing, in a range of public health agencies, an intense, evidence-based behavioral weight loss intervention with demonstrated…
- Conditions
- Overweight, Obesity, Cardiovascular Disease
- Trial name
- Weight-Wise (NCT01141348)
- Testing
- Special Intervention, Delayed Intervention
- Where
- 6 sites in United States
- Volunteers
- 189 people
- Sponsor
- University of North Carolina, Chapel Hill
Mortality in Intensive Care Units, Complications Infection
Intensive Care Unit Risk Score
Subject of the planned project is the retrospective analysis of routine data of digital patient files of the Department for Anaesthesiology and Surgical Intensive Care Medicine, to test whether the predictive values of intensive…
- Conditions
- Mortality in Intensive Care Units, Complications Infection, Alarm Fatigue
- Trial name
- ICURS (NCT04661735)
- Where
- Germany
- Volunteers
- 60,000 people
- Sponsor
- Charite University, Berlin, Germany