Clinical trials: Intensive Care, Neonatal
Shock, Sepsis
Hemodynamic Evaluation of Preload Responsiveness in Children by Using PiCCO
The purpose of this study is To assess the value of dynamics (SVV, PPV) and static indices (GEDVI, ITBVI, CVP) of preload and its combination with contractility (CI,SV, ventricular power, dP/dtmax, CFI, GEF) and lung water…
- Conditions
- Shock, Sepsis, Systemic Inflammatory Response Syndrome, Low Cardiac Output
- Trial name
- PreloaDren (NCT01157299)
- Where
- 7 sites in Spain
- Volunteers
- 100 people
- Sponsor
- Hospital Universitario La Paz
Alert Fatigue, Health Personnel
Intervention Program for Alarm Fatigue in NICU Nurses Based on ABC-X Model
Monitors in newborn intensive care (NICU) help keep babies safe, but the constant beeping can overwhelm nurses. This 'alarm fatigue' makes it harder for nurses to identify real emergencies, stresses them out, and can impact…
- Trial name
- NCT07025863
- Testing
- Alarm Fatigue Intervention Program
- Where
- China
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Guizhou Medical University
Newborns, Neonatology
Interest of Peripheral Venous Catheter Insertion Using a Micro-guide in Neonatology
Peripheral venous catheterization represents the preferential option for term or preterm infant care in order to start drug treatment or hydration, or perform anesthesia.
- Conditions
- Newborns, Neonatology, Intensive Care
- Trial name
- EASYCATH (NCT04984967)
- Testing
- Insertion of peripheral venous catheter with micro-guide, Classic insertion of peripheral venous catheter, without micro-guide
- Where
- France
- Volunteers
- 116 people
- Sponsor
- University Hospital, Montpellier
Whole Genome Sequencing, Genetic Disease
N-Care Project: Enhancing Asian-Pacific Collaboration
Through Asian-Pacific multinational collaboration, we aim to utilize third-generation genome sequencing to rapidly diagnose genetic diseases in critically ill infants and young children, achieving the goal of early diagnosis for…
- Conditions
- Whole Genome Sequencing, Genetic Disease, Critical Care, Intensive Care, Nanopore Sequencing
- Trial name
- N-Care project (NCT06821386)
- Testing
- Genetic study with nanopore sequencing
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- National Taiwan University Hospital
Preterm Neonates, Apnea of Prematurity
The Effect of Caffeine Therapy in Cardiovascular Stability in Preterm Neonates at Assiut University Children Hospital NICU
Preterm neonates younger than 37 weeks gestational age receiving caffeine therapy for apnea of prematurity in a NICU setting.
- Trial name
- NCT07274969
- Volunteers
- 40 people
- Sponsor
- Assiut University
Very Low Birth Weight Infant
The Effect of Family Integrated Care on Melatonin Level in Very Low Birth Weight Infants
This study will explore the effect of Family integrated care (FICare) on the level of melatonin and other clinical outcomes in very low birth weight infants (VLBWIs) by integrating families into the neonatal intensive care unit…
- Trial name
- NCT05483231
- Testing
- Family integrated care intervention group, Routine nursing care group
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Children's Hospital of Fudan University
Prematurity
Ultrasound Monitoring of Muscle Thickness in Premature Patients
The goal of this interventional study is to investigate through musculoskeletal ultrasonography how the thickness and muscle trophism in infants aged 28 to 35 weeks undergoing infant massage compared with a group of infants with…
- Trial name
- NeoMassage (NCT06273202)
- Testing
- Infant Massage
- Where
- Italy
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Breast Milk Expression, Breast Milk Collection
The Effect of Showing Photographs, Videos and Live Images of Their Babies to Mothers During Milking
The study was planned to determine the effect of showing photographs, videos and live images of premature babies who could not be breastfed in the neonatal intensive care unit to their mothers on the amount of breast milk…
- Conditions
- Breast Milk Expression, Breast Milk Collection, Mother-Infant Interaction
- Trial name
- NCT05700162
- Testing
- Photograph, Video, Live Broadcast
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Respiration, Artificial, Hemorrhage
Impact of Heparin on the Need for Mechanical Ventilation in Neonates
This study is designed to test an incidental finding of a previous trial in which post hoc analysis showed that the rate of intensive care newborns requiring mechanical ventilation was lower in the group receiving heparin with…
- Trial name
- NCT00196469
- Testing
- heparin
- Where
- Germany
- Volunteers
- 270 people
- Sponsor
- University Medicine Greifswald
Acute Kidney Injury, Congenital Heart Disease
Acute Kidney Injury After Cardiac Surgery on CPB
The purpose of this retrospective study is to determine the incidence and severity of acute kidney injuries (AKI) after heart surgery on cardiopulmonary bypass (CPB) in the pediatric intensive care unit (PICU) in Lausanne…
- Conditions
- Acute Kidney Injury, Congenital Heart Disease, Surgery, CBP
- Trial name
- NCT03513718
- Where
- Switzerland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Premature Birth
Listening to Mom 2: Neural, Clinical and Language Outcomes
The purpose of this study is to examine whether playing recordings of a mother's voice to her infant while in the hospital nursery is an effective treatment for promoting healthy brain and language development in infants born…
- Trial name
- NCT04193579
- Testing
- Language Treatment, Control Treatment
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Stanford University
Preterm Birth, Premature Birth
Exposure to Plasticisers in the Neonatal Intensive Care Unit
Neonatal intensive care relies on indwelling plastic medical devices fundamental in respiratory support, intravenous catheterization, and nutrition.
- Conditions
- Preterm Birth, Premature Birth, Neurodevelopmental Disorders, Pulmonary Disease
- Trial name
- PLASTIC-NICU (NCT05404815)
- Where
- Belgium
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Intensive Care Units Neonatal, Parenting
A Mobile Web-Based Parenting Intervention to Strengthen Social-Emotional Development of Low Birth Weight Infants
Low birth weight (LBW) infants are at significantly elevated risk for a host of detrimental outcomes including cognitive, language, and social delays and disabilities, which persist into adulthood.
- Conditions
- Intensive Care Units Neonatal, Parenting, Infant Health
- Trial name
- NCT05532202
- Testing
- NICU Mom and Baby Net, NICU Developmental Awareness System
- Volunteers
- 102 people
- Sponsor
- Georgia State University
Infant, Premature, Diseases, Mothers
Home Support for Mothers Whose Premature Infants
Premature births are a challenging process for parents in many ways. Especially after the treatment and care in the hospital, they are concerned about whether they will be able to provide adequate care for their baby at home.
- Trial name
- NCT04741672
- Testing
- Providing guidance after discharge routine procedure and calling one week after discharge., Discharge routine procedure.
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Congenital Heart Defect, Respiratory Distress Syndrome in Premature Infant
Neonatal Cardio-Pulmonary Outcome Measure
Neonatal Cardio-Pulmonary outcome measure (N-COM) will be used to assess the overall status of pulmonary and cardiac vascular system of neonates in Neonatal Intensive Care Unit (NICU).
- Trial name
- N-COM (NCT04324957)
- Testing
- Neonatal cardio-pulmonary outcome measure used to assess cardio-pulmonary status
- Where
- India
- Volunteers
- 30 people
- Sponsor
- Asir John Samuel
Newborn
Comparison of Open and Closed Aspiration in Newborns
Endotracheal aspiration is a necessary procedure performed by nurses in neonatal intensive care units to increase oxygenation and remove secretions from the airways.
- Trial name
- NCT06435572
- Testing
- Suction
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Izmir Katip Celebi University
Breastfeeding
The Effect of Podcast Breastfeeding Training on Mothers of Preterm Infants
The aim of this study is to examine the effect of breastfeeding education provided via podcast to mothers of preterm infants admitted to the neonatal intensive care unit on the mothers' breastfeeding success, awareness…
- Trial name
- NCT07660965
- Testing
- Breastfeeding education via podcast
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Dilek Kucuk Alemdar
Genetic Disease, Multiple Malformation
Genomic Sequencing and Personalized Treatment for Birth Defects in Neonatal Intensive Care Units
The purpose of study is to evaluate the benefits of using the Next Generation Sequencing Technology to diagnose birth defects and genetic diseases.
- Conditions
- Genetic Disease, Multiple Malformation, Congenital Malformation
- Trial name
- NCT02551081
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Children's Hospital of Fudan University
Premature Birth
Effectiveness of Music Therapy on the Development of Preterm Neonates
Pragmatic, randomized controlled clinical trial with blinding of the evaluator, performed in order to estimate the effectiveness, six (6) months after hospital discharge, of music therapy on the intra-hospital evolution and…
- Trial name
- EMT-DRNP (NCT02948491)
- Testing
- Music therapy
- Where
- Colombia
- Volunteers
- 90 people
- Sponsor
- Universidad Manuela Beltrán
Early Intervention, Prematurity
Effects of Early Vocal Contact (EVC) in the Neonatal Intensive Care Unit
Background: Preterm infants are at risk for developing altered trajectories of cognitive, social, and linguistic competences compared to a term population.
- Trial name
- EVC (NCT04759573)
- Testing
- Early Vocal Contact, Behavioral Observation
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Elisa Della Casa Muttini