Clinical trials: Intensive Care (ICU) Myopathy
Intensive Care (ICU) Myopathy
Physical Function in Critical Care (PaciFIC)
Impairment in physical function is a significant problem for survivors of critical illness. There is a growing urgency to develop a core set of outcome measures, which can be adopted in clinical and research practice to evaluate…
- Trial name
- PaciFIC (NCT02911896)
- Where
- 4 sites in Australia, Brazil and 1 more
- Volunteers
- 151 people
- Sponsor
- University of Melbourne
Muscle Atrophy, Muscle Weakness
Neuromodulation for Prevention of Intensive Care Unit Acquired Weakness and Post Intensive Care Syndrome
Post-intensive care syndrome (PICS) encompasses persistent physical, cognitive, and psychiatric symptoms following ICU discharge, commonly triggered by serious conditions such as respiratory failure, sepsis, and mechanical…
- Conditions
- Muscle Atrophy, Muscle Weakness, Blood Flow
- Trial name
- NCT06238609
- Testing
- Intervention Group, Control Group
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Bijan Najafi, PhD
COVID-19 Acute Respiratory Distress Syndrome
Rehabilitation of Critically Ill Patients With SARS-CoV-2 Variants in ICU With Limited Resources
Acute rehabilitation in critically ill patients can improve post-intensive care unit (post-ICU) physical function. Scientific evidence has considered neuromuscular electrical stimulation (NMES) as a promising approach for the…
- Trial name
- NCT05450120
- Testing
- Functional Rehabilitation, Neuromuscular Electrical Stimulation
- Where
- Brazil
- Volunteers
- 88 people
- Sponsor
- Universidade Federal de Sao Carlos
Intensive Care (ICU) Myopathy, Functional Independence
Correlation Between Spirometry and Functional Independence in Adult Post-ICU Patients
Several complications and comorbidities are frequently found in patients admitted to an Intensive Care Unit (ICU), including acquired ICU muscle weakness and physical and cognitive limitations.
- Trial name
- NCT03619915
- Testing
- Spirometry, Functional Independence Measure
- Volunteers
- 197 people
- Sponsor
- Universidade Estadual do Oeste do Paraná
Muscle Weakness, Rehabilitation
Efficacy of Different Treatments for the Intensive Care Unit Acquired Weakness
Experimental study that has how to compare the efficacy between conventional rehabilitation, transcutaneous electrostimulation or early mobilization to reduce the time needed to reverse the muscle weakness evaluated by the muscle…
- Trial name
- NCT04613908
- Testing
- neuro muscular electro stimulation, Early Mobilization protocol, standard care or usual rehabilitation
- Volunteers
- 18 people
- Sponsor
- Hospital Nacional Profesor Alejandro Posadas
Covid-19, Critical Illness
Optimizing Outcomes With Physical Therapy Treatment for IndividuALs Surviving an ICU Admission for Covid-19
Introduction: Survivors of acute respiratory failure develop persistent muscle weakness and deficits in cardiopulmonary endurance combining to limit physical functioning.
- Conditions
- Covid-19, Critical Illness, Post Intensive Care Unit Syndrome, Muscle Weakness
- Trial name
- OPTIMAL (NCT04412330)
- Testing
- ICU Recovery + Physical Therapy
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Kentucky
Intra-Abdominal Hypertension
Intra-abdominal Hypertension and Associated Factors Among Patients Admitted in Intensive Care Units in Uganda.
The study was carried out to determine the prevalence,incidence and factors associated with intra-abdominal hypertension among patients admitted in three intensive care units in Kampala Uganda.
- Trial name
- NCT03567265
- Where
- Uganda
- Volunteers
- 126 people
- Sponsor
- Makerere University
Muscle Weakness, Critical Illness
Assessing The Effects of Exercise, Protein, and Electric Stimulation On Intensive Care Unit Patients Outcomes
Elderly patients who experience a prolonged ICU stay are at high risk for developing post intensive care unit syndrome (PICS), a serious medical condition manifested by loss of muscle mass, weakness, malnutrition and…
- Conditions
- Muscle Weakness, Critical Illness, Sarcopenia
- Trial name
- ExPrEs (NCT02509520)
- Testing
- MPR and High Protein Supplement (HPRO) and Neuromuscular Electric Stimulation (NMES)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Maryland, Baltimore
Rhabdomyolysis
Pediatric Rhabdomyolysis in the Pediatric Intensive Care Unit: A Retrospective Cohort Study
This retrospective observational cohort study aims to evaluate the clinical characteristics, causes, intensive care management, and outcomes of pediatric patients with rhabdomyolysis admitted to the Pediatric Intensive Care Unit…
- Trial name
- NCT07851987
- Where
- Germany
- Volunteers
- 55 people
- Sponsor
- Hannover Medical School
Critical Illness Myopathy, Respiration, Artificial
Electrical Stimulation of the Quadriceps and Diaphragm in Critically Ill Patients
Subjects in MV will be included, divided into 3 groups: (a) Control Group (CG), (b) Stimulation of Quadriceps (Quadriceps Group - QG), (c) Stimulation of Diaphragm (Diaphragm Group - DG).
- Trial name
- NCT03352102
- Testing
- Electrical stimulation
- Where
- Brazil
- Volunteers
- 41 people
- Sponsor
- Pericles Almeida Delfino Duarte
Critical Illness Myopathy, Myopathy Critical Illness
Understanding the Mechanisms of Critical Illness Myopathy by Use of a Novel Electrophysiological Method - MVRCs
Critical illness myopathy (CIM) is a disabling condition that develops in critically ill patients. The syndrome is not only a cause of prolonged intensive care hospitalisation but also a main reason for delayed recovery.
- Trial name
- NCT04711070
- Where
- 2 sites in Denmark
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Sándor Beniczky
Spinal Cord Injuries
Assessment of the Effects of Early Proprioceptive Stimulations in Patients With Spinal Cord Injury
"Spinal cord injury (SCI) is a dramatic event resulting in a long-term handicap. Appropriate care from admission to the intensive care unit (ICU) is a key element not only for the survival of these patients but also to promote…
- Trial name
- Tetra-Mouv (NCT05094752)
- Testing
- Proprioceptive stimulations
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Intensive Care (ICU) Myopathy
Biomechanical Properties in Intensive Care Unit (ICU) Survivors 12-month After Discharge
Intensive care unit (ICU) admission is associated with muscle weakness and ICU survivors report persevering limitation of physical capacity for years after discharge.
- Trial name
- NCT01364714
- Where
- Denmark
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Critical Illness, Muscle Weakness
Correlation Between Muscle Strength and Thickness in Critically Ill Patients
Mechanical ventilation (MV) is associated with adverse outcomes in ventilated patients, and impact of MV-induced diaphragm changes are still unclear.
- Trial name
- NCT06289244
- Testing
- Ultrasound, Muscle strength measurement
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Polyneuropathies, Septic Shock
Electrical Muscle Stimulation in the Development of Acquired Weakness in Patients With Severe Sepsis and Septic Shock
The aim of this study is to compare the effect of EMS and conventional physical therapy on strength and muscle mass and development in adult patients with severe sepsis and septic shock.
- Conditions
- Polyneuropathies, Septic Shock, Muscle Weakness
- Trial name
- NCT03765489
- Testing
- electrical muscle stimulation, conventional physical therapy
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Chile
Critical Illness, Intensive Care (ICU) Myopathy
Early Goal-Directed Nutrition in ICU Patients - EAT-ICU Trial
An increasing number of patients survive critical illness and intensive care, but describe having impaired physical function several years after discharge as a consequence of extensive loss of muscle mass.
- Conditions
- Critical Illness, Intensive Care (ICU) Myopathy, Muscle Wasting, Loss of Physical Function
- Trial name
- EAT-ICU (NCT01372176)
- Testing
- Early Goal-Directed Nutrition, ASPEN-guidelines
- Where
- Denmark
- Volunteers
- 203 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Intensive Care Unit Syndrome, Muscle Weakness
Effect of Critical Patients Mobilization on Respiratory and Peripheral Muscle Strength and Functional Capacity.
To analyze changes on respiratory muscle strength, peripheral and functional capacity of critically ill patients with clinical and surgical etiology, breathing spontaneously and bedridden, within 48 hours of admission to the…
- Trial name
- NCT02919085
- Testing
- Early ambulation
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Universidade Federal de Pernambuco
Muscle Weakness, Critical Illness
New Onset Weakness in Critically Ill Patients and the Risk of Death and Recurrent ICU Admission
This study seeks to define the morbidity of critical care polyneuropathy and to confirm that this diagnosis is, in fact, independently associated with increased mortality.
- Trial name
- NCT00106665
- Where
- 5 sites in United States
- Volunteers
- 170 people
- Sponsor
- Naeem Ali, MD
Motor Activity, Muscle Strength
Critical Care Observation of Motor Activity (COMA) and SICU Outcomes
In the surgical intensive care unit (SICU), goals of critical care are often discussed in long-term ventilated patients around the time of extubation.
- Conditions
- Motor Activity, Muscle Strength, Muscle Weakness
- Trial name
- COMA (NCT02994641)
- Testing
- COMA Score Assessment
- Where
- United States
- Volunteers
- 761 people
- Sponsor
- Massachusetts General Hospital
Weakness, Muscle
Bed Rest and Muscle Strength in ICU: Interest in the Early Association of NEMS With Cyclo-ergometer Mobilization
Muscles atrophy and weakness are common in intensive care units, their origin is multifactorial. Passive then active mobilization with cyclo-ergometer have shown to improve functional abilities and limit muscle weakness among…
- Trial name
- AFMPR (NCT03987997)
- Testing
- Early association of electrical muscle stimulation with cyclo-ergometer
- Where
- France
- Volunteers
- 55 people
- Sponsor
- Direction Centrale du Service de Santé des Armées