Clinical trials: Intensive Care Medicine
Waiting-time in the Anaesthesia Admissions Ambulance
Optimizing of Waiting - Time in the Anesthesia Admissions Ambulance of the Charité - University Medicine Berlin by Support of a Mobile Application - a Pilot Study
In this study the investigators measure and optimize the patients waiting time in the preanesthetic assessment by integrating an interactive mobile device.
- Trial name
- NCT02457767
- Sponsor
- Charite University, Berlin, Germany
Intensive Care Medicine, Acute Care Medical
Functional Incremental Stepping in Place Test (F-IST) Validation
The purpose of this multi-site prospective study is to assess validity of a new step test called Functional-Incremental Stepping-in-place- Test (F-IST) compared to gold-standard cardiopulmonary exercise testing (CPET) and to…
- Trial name
- F-IST (NCT06853236)
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kirby Mayer
Acute Respiratory Failure (ARF), Intermediate Respiratory Care Unit
BELLRICU PROJECT: Precision Medicine in Respiratory Intermediate Care Units
A respiratory intermediate care unit (RICU) is a monitoring and treatment area of respiratory patients who do not required admission to intensive care unit (ICU) but due to complexity, they could not be managed in conventional…
- Conditions
- Acute Respiratory Failure (ARF), Intermediate Respiratory Care Unit, Respiratory Precision Medicine, Mortality Prediction
- Trial name
- BELLRICU (NCT07644637)
- Where
- Spain
- Volunteers
- 624 people
- Sponsor
- Hospital Universitari de Bellvitge
Intensive Care Medicine, Critical Care
Evaluating the Use of Artificial Intelligence to Improve Family Conversations for Intensive Care Patients and Their Families
This study looks at how artificial intelligence (AI), like generative pre-trained transformer (GPT-4), can help doctors in the intensive care unit (ICU) save time and improve communication with families.
- Trial name
- NCT06756542
- Where
- 2 sites in Netherlands
- Volunteers
- 40 people
- Sponsor
- Davy van de Sande
Critical Care Medicine, Mortality Prediction
Clinical Validation of a Pre-trained and Fine-tuned Model for Analyzing Time-Series Electronic Health Records in Critical Care
The goal of this observational study is to validate the generalization capability and predictive performance of the "Time-Series Electronic Health Record Foundation Model (EHR Foundation Model)", which was pre-trained on a…
- Trial name
- NCT07795450
- Where
- China
- Volunteers
- 4,800 people
- Sponsor
- Peking University People's Hospital
Sedative Drug Consumption, Mechanically Ventilated ICU Patients
Efficacy of Music on Reduction of Sedative Drugs in Mechanically Ventilated Intensive Care Unit Patients
Major objective: a three-days interventional cross-over trial [one day music on, one day wash-out, one day music off][two periods of listening/day], to evaluate: 1. Impact on sedative drug consumption. 2.
- Trial name
- MUSIC (NCT00880035)
- Testing
- MP3 music program listening
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Université de Sherbrooke
Multi-Drug Resistant Organisms, Late-Onset Sepsis, Neonatal
Using Antibiotics Wisely - An Antimicrobial Stewardship Program
There are significant variations in antimicrobial consumption across Canadian Neonatal Intensive Care Units (NICUs). Inappropriate and overuse of antibiotics can result in antimicrobial resistance and adverse outcomes among…
- Conditions
- Multi-Drug Resistant Organisms, Late-Onset Sepsis, Neonatal, Antimicrobial Resistance
- Trial name
- NCT04388293
- Testing
- Exposure of interest
- Where
- Canada
- Volunteers
- 2,000 people
- Sponsor
- University of British Columbia
Drug Therapy
Safety Analysis of Antimicrobial Pharmacotherapy in Intensive Care Unit at Pediatric Hospital
Changes in the metabolic ability of cytochrome P-450 during child development can affect both bioavailability and elimination depending on the involvement of intestinal and hepatic metabolic processes.
- Trial name
- NCT04141657
- Testing
- Pharmacogenetic test
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- Anna Vlasova
Acute Kidney Injury
Post-Cardiac Surgery Acute Kidney Injury Prevention by Administration of Proton Pump Inhibitor (P2 Trial)
The central hypothesis of this research study is that perioperative administration of the proton pump inhibitor (PPI) pantoprazole could reduce the development of acute kidney injury (AKI) following cardiac surgery by activation…
- Trial name
- P2 AKI PPI (NCT06706258)
- Testing
- Protonix (Pantoprazole) 40 mg q 12 hrs for 3 days, Pepcid (Famotidine) 20 mg q 12 hrs for 3 days
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- The University of Texas Health Science Center, Houston
Type II Diabetes, Cardiovascular Disease
Intensive Discharge Intervention in Diabetes
The goal of this study is to design and implement an intensive discharge intervention for inpatients with type 2 diabetes and cardiovascular disease, and determine the effects of the intervention on post-discharge insulin…
- Trial name
- IDID (NCT02122926)
- Testing
- Intensive discharge intervention
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Brigham and Women's Hospital
Liver Cirrhosis, Viral Pneumonia
Liver Cirrhosis Patients With Invasive Pulmonary Aspergillosis: in Depth Understanding Clinical Host Risk Factors
Invasive pulmonary aspergillosis (IPA) is a life-threatening fungal infection of the respiratory system, caused by a specific fungus called Aspergillus species.
- Conditions
- Liver Cirrhosis, Viral Pneumonia, Fungal Infection, Invasive Pulmonary Aspergillosis
- Trial name
- LIVERIPA (NCT07238114)
- Where
- Belgium
- Volunteers
- 450 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Intensive Care Unit Patients
Therapeutic Drug Monitoring of Antifungals in Intensive Care Units
Antifungals under- and over-dosing are frequently deplored in patients treated with antifungals and receiving recommended doses, mostly in critically-ill patients.
- Trial name
- Fungi-up (NCT04502771)
- Testing
- Antifungal treatment
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Hospices Civils de Lyon
VAP - Ventilator Associated Pneumonia
The Effectiveness of the Modified Bundle in the Prevention of VAP.
Ventilator-associated pneumonia (VAP) is an important cause of prolonged intensive care unit and hospital length of stay, healthcare costs and mortality in mechanically ventilated patients.
- Trial name
- VAP (NCT04038814)
- Testing
- Routine prevention of VAP, Modified prevention of VAP
- Where
- Poland
- Volunteers
- 386 people
- Sponsor
- Andrzej Frycz Modrzewski Krakow University
Critical Illness
Exploration of Investigating ICU Mobilisation With Vasoactive Drugs
There is a need to know more about the safety of mobilizing intensive care unit (ICU) patients who are receiving vasoactive drugs that support the heart and blood pressure.
- Trial name
- NCT03869541
- Testing
- Mobilization
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Critical Illness, Brain Injuries
Therapeutic Drug Monitoring of Beta-lactams and Renal Hyperclearance in Patients Admitted to Intensive Care for Acute Brain Injury
Augmented Renal Clearance (ARC), defined as a supraphysiological increase in renal function, is frequently observed in critically ill patients, particularly those with acute brain injury.
- Trial name
- BETALACT-ARC (NCT06999161)
- Where
- France
- Volunteers
- 140 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Medicines Reconciliation, Intensive Care Unit
Medicines Reconciliation at an Intensive Care Unit
This study evaluates the effect of performing medicines reconciliation on patients admitted to an intensive care unit. Half of the patients will receive a medicines reconciliation at the intensive care unit.
- Trial name
- NCT03173690
- Testing
- Medication reconciliation at the ICU, Medication Reconciliation at the Ward
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- University Hospital, Akershus