Clinical trials: Intensive Care Patients
Respiratory Failure, Tracheostomy Complication
Ventilation Weaning Strategies and Correlation to Outcomes in Tracheostomized Patients in the Lausanne ICU
This retrospective study aims to study characteristics of patients tracheotomized in the Lausanne ICU, both overall and by primary reasons of intubation.
- Trial name
- NCT04987398
- Where
- Switzerland
- Volunteers
- 80 people
- Sponsor
- Piquilloud Imboden Lise
Coronavirus Infection, Intensive Care Patients
Effects on the Qt Interval of COVID-19 Coronavirus Infection
The present study aims to evaluate the impact of COVID-19 disease and its treatment on ventricular repolarization, assessed by measuring the QTc interval, in patients admitted to the critical care unit.
- Trial name
- QT-COVID-19 (NCT04422535)
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Matilde Zaballos
Pediatric Critical Illness
Transcutaneous pO₂ Monitoring in PICU
Arterial blood gas analysis is commonly used in pediatric intensive care units (PICUs) to assess oxygen and carbon dioxide levels in critically ill children.
- Trial name
- NCT07478380
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul Medeniyet University
Critical Illness, Body Weights
Energy Expenditure in ICU Patients Using Predictive Formulas and Various Body Weights Versus Indirect Calorimetry
Indirect calorimetry is the gold standard to measure energy expenditure. In fact it is not always available and inconstantly feasible. Various equations for predicting energy expenditure based on body weights have been created.
- Trial name
- NCT02552446
- Where
- Switzerland
- Volunteers
- 87 people
- Sponsor
- University Hospital, Geneva
Prevalence, Diabetes Mellitus
Prevalence and Impact of Diabetes Mellitus in Hospitalized COVID-19 Patients in a Tunisian Center
Objective: The objective of this study was to evaluate the prevalence and impact of diabetes mellitus on the severity and mortality of COVID-19.
- Conditions
- Prevalence, Diabetes Mellitus, Impaction, COVID-19
- Trial name
- NCT05851820
- Testing
- comparison of outcomes/exposure
- Where
- Tunisia
- Volunteers
- 866 people
- Sponsor
- Sana Rouis
ICP (Intracranial Pressure) Increase, Optic Nerve Sheath Diameter
Optic Nerve Sheath Diameter: A Non-Invasive Indicator of Intracranial Pressure in the Intensive Care Unit Monitoring
Determination of high intracranial pressure (ICP) is necessary for the treatment of patients with raised ICP to improve long-term neurological outcomes.
- Conditions
- ICP (Intracranial Pressure) Increase, Optic Nerve Sheath Diameter, Intracranial Hypertension
- Trial name
- NCT06367868
- Testing
- After 5 ml CSF Drainage
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Istanbul University - Cerrahpasa
Tracheal Stenosis, Intensive Care Unit
Long-term Outcomes of Post-intubation Tracheal Stenosis; 7-year Follow-up
This retrospective, observational, cohort study evaluates the treatment management, long-term outcomes and survival analyses in patients hospitalized in the Intensive Care Unit with a diagnosis of Post-Intubation Tracheal…
- Trial name
- NCT06121024
- Testing
- Interventional Bronchoscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
Subarachnoid Hemorrhage, Traumatic Brain Injury
Intensive Insulin Therapy for Strict Glycemic Control in Neurosurgical Patients: Safety and Efficacy
Strict glycemic control improves mortality and morbidity of patients admitted to the postoperative intensive care unit (ICU). The investigators would like to know if this therapy could improve the long term neurologic and…
- Conditions
- Subarachnoid Hemorrhage, Traumatic Brain Injury, Intracranial Hemorrhage
- Trial name
- NCT00505505
- Testing
- Insulin (Actrapid)
- Where
- Italy
- Volunteers
- 800 people
- Sponsor
- University of Roma La Sapienza
Severe Sepsis
Investigation of Correlation Between Interstitial and Arterial Blood Glucose Concentrations in Septic Patients
This is a mono-centre trial performed at the medical ICU at the Medical University Graz. There will be a study visit (V1) and a follow-up assessment (V2).
- Trial name
- NCT00463645
- Testing
- microdialysis, microperfusion
- Where
- Austria
- Volunteers
- 10 people
- Sponsor
- Medical University of Graz
Bacterial Infections
Direct Molecular Characterization of Bacteria From ICU and From the REHAB
Investigators aim to directly investigate the molecular properties of bacteria from tracheal and urinary samples routinely taken in intensive care units (ICU) patients.
- Trial name
- NCT03475472
- Where
- 2 sites in Switzerland
- Volunteers
- 971 people
- Sponsor
- University Hospital, Basel, Switzerland
Diarrhea Caused by Drug, Clostridium Difficile Infections
Faecal Bacteriotherapy for Postantibiotic Diarrhoea in Critically Ill Patients
Rationale: Postantibiotic diarrhoea in critically ill patients is common, often prolonged and currently there is no effective treatment of it.
- Trial name
- FEBATRICE (NCT05430269)
- Testing
- Faecal bacteriotherapy (FBT), standard-of-care protocolised treatment of postantibiotic diarhea
- Where
- 2 sites in Czechia
- Volunteers
- 36 people
- Sponsor
- Charles University, Czech Republic
Critically Ill, Haemodynamic Instability
Transducer Levelling Errors in Everyday ICU Practice - A Multicentre Blinded Observational Study
Invasive pressure monitoring (arterial blood pressure via arterial catheter and central venous pressure via central venous catheter) is fundamental to clinical decision-making in intensive care.
- Trial name
- NCT07330505
- Where
- 2 sites in Sweden
- Volunteers
- 60 people
- Sponsor
- Vastra Gotaland Region
Virtual Reality, Intensive Care Unit Acquired Weakness
The Effects of Virtual Reality in Intensive Care Patients
Weakness of respiratory muscles delays weaning from the ventilator, prolongs hospital stay and increases treatment costs. Conventional treatments for respiratory muscles reverse these negative effects.
- Trial name
- NCT06442254
- Testing
- Virtual Reality
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Istinye University
Pressure Injuries, Skin Failure
Barrier Functions oF Skin in ICU: SKIN-BAR
This study aims to investigate skin barrier function in intensive care unit (ICU) patients using biosensor-based measurements. Biophysical parameters including transepidermal water loss (TEWL), skin pH, stratum corneum hydration…
- Conditions
- Pressure Injuries, Skin Failure, Skin Abnormalities, Biophysical Parameters of Skin
- Trial name
- SKIN-BAR (NCT07560683)
- Where
- Turkey (Türkiye)
- Volunteers
- 156 people
- Sponsor
- Koç University
Pediatric Disorders
PHYSIOFLOW/Comparison of Cardiac Output Measurement
PhysioFlow® (PF®) is a new cardiac output (CO) monitoring method by impedance cardiography (IC), never studied in pediatric intensive care unit (PICU).
- Trial name
- PF-ECHO (NCT02873494)
- Testing
- PHYSIOFLOW - PF05 Lab1TM
- Where
- France
- Volunteers
- 43 people
- Sponsor
- University Hospital, Lille
Acute Kidney Injury
Renal Angina Index for Predicting Acute Kidney Injury in Adult ICU Patients
Acute kidney injury (AKI) is a frequent complication of critical illness and is associated with increased morbidity and mortality.
- Trial name
- NCT07863505
- Testing
- Renal Angina Index Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 324 people
- Sponsor
- Izmir Katip Celebi University
Oxygen Deficiency
Incidence of Use of High-Flow Nasal Cannula Oxygen Therapy in Intensive Care Units Patients
Patients with one or more organ failure (heart, lung) require hospitalization in intensive care where these failures can be managed.
- Trial name
- OHE-REA (NCT04141956)
- Testing
- High-Flow Nasal Cannula
- Where
- 10 sites in France
- Volunteers
- 257 people
- Sponsor
- Nantes University Hospital
Tracheostomy Hemorrhage
Tracheotomy With and Without Dual Antiplatelet Therapy
Platelet-inhibiting drugs are often used after vascular interventions. Patients who require such therapies are often critically ill, are treated in intensive care units and often require long-term ventilation.
- Trial name
- PDT and (D)APT (NCT05058469)
- Testing
- Tracheotomy
- Where
- Germany
- Volunteers
- 300 people
- Sponsor
- Asklepios Neurological Clinic Bad Salzhausen
Critically Ill
Pilot Study on Gastro-intestinal (GI) Enteral Nutrition (EN) Tolerance in Intensive Care Unit Patients
Specifically designed enteral formulations may improve the gastrointestinal tolerance during early enteral nutrition in the critically ill patient.
- Trial name
- SPIRIT (NCT01581957)
- Testing
- Specific Enteral Nutrition, Standard Enteral Nutrition
- Where
- Switzerland
- Volunteers
- 90 people
- Sponsor
- Société des Produits Nestlé (SPN)
Critical Illness, Social Isolation
Reducing Isolation and Feeling of Loneliness During Critical Illness
The trial is a pilot-randomized trial testing feasibility and limited-efficacy of delivering social engagement using technologic strategies to reduce periods of social isolation.
- Conditions
- Critical Illness, Social Isolation, Anxiety, Depression
- Trial name
- SOCIAL (NCT05537311)
- Testing
- Social Engagement
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Kirby Mayer