Clinical trials: Intensive Care Patients on a Ventilator
Critical Illness, Post Intensive Care Unit Syndrome
pEEG Monitoring Effect on Delirium, Ventilator Days, and PICS
The goal of this multi-site observational study is to compare delirium rates, days on mechanical ventilation, and Post Intensive Care Syndrome (PICS) rates in adult Intensive Care Unit (ICU) patients.
- Conditions
- Critical Illness, Post Intensive Care Unit Syndrome, Post Intensive Care Syndrome, Mechanical Ventilation Complication
- Trial name
- NCT06019078
- Testing
- SedLine
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Fraser Health
Post-Intensive Care Syndrome (PICS), Critical Illness Recovery
Integrated Rehabilitation in HDU for Post-Intensive Care SyndromeLiberation in Patients With PICS
Post-intensive care syndrome (PICS) is characterized by persistent physical, cognitive, and psychological impairments among survivors of critical illness.
- Conditions
- Post-Intensive Care Syndrome (PICS), Critical Illness Recovery, Mechanical Ventilation
- Trial name
- NCT07521540
- Testing
- Integrated Multidisciplinary Rehabilitation
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Hongying Jiang, MD
Infection, Intensive Care (ICU)
The Effect of an Suction Toothbrush on the Development of Ventilator-Associated Pneumonia
Literature suggests that suction toothbrushes may improve oral care in intubated patients by facilitating secretion removal and reducing microaspiration.
- Conditions
- Infection, Intensive Care (ICU), Intubation, Intubation Complication
- Trial name
- Toothbrush (NCT07125495)
- Testing
- Suction tootbrush and distiled water, suction tootbrush and .12% chlorhexidine gluconate, Oral care sponge and with 15 ml of 0.12% chlorhexidine gluconate oral solution
- Where
- Turkey (Türkiye)
- Volunteers
- 111 people
- Sponsor
- Koç University
Respiratory Failure
Effect of Inspiratory Muscle Training on Duration of Mechanical Ventilation Support
A growing body of knowledge has documented that the diaphragm, the primary muscle of breathing, atrophies and weakens within days of instituting mechanical ventilation support.
- Trial name
- NCT01108575
- Testing
- IMST
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- University of Florida
Agitation
Acupuncture to Improve Comfort of Children on a Ventilator in the Intensive Care Unit
The purpose of this study is to determine whether acupuncture is effective at improving comfort in children on a ventilator in the intensive care unit.
- Trial name
- NCT01848158
- Testing
- acupuncture
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Seattle Children's Hospital
Weaning From Mechanical Ventilation
Comparison of the Impact of Three Programs of Inspiratory Muscles.
Ventilator-induced diaphragmatic dysfunction appears to contribute to slow weaning from mechanical ventilation. Several trials of inspiratory muscle training to facilitate weaning in intensive care have been performed, with…
- Trial name
- PREDRIC (NCT02855619)
- Testing
- Martin, Cader, EDRIC
- Where
- 2 sites in France
- Volunteers
- 92 people
- Sponsor
- University Hospital, Bordeaux
Aged, Intensive Care Units
Dexmedetomidine-Esketamine Combination for Sedation and Analgesia in ICU Patients
Patients with mechanical ventilation in the intensive care unit (ICU) often develop anxiety and agitation, sleep distuebances, and delirium. Delirium occurrence is associated with worse early and long-term outcomes.
- Conditions
- Aged, Intensive Care Units, Ventilators, Mechanical, Dexmedetomidine
- Trial name
- NCT06468436
- Testing
- Dexmedetomidine-Esketamine Combination, Dexmedetomidine
- Where
- 3 sites in China
- Volunteers
- 1,508 people
- Sponsor
- Peking University First Hospital
Ventilator Associated Events, Asynchrony, Patient-Ventilator
Synchrony-Optimized Non-Invasive Ventilation Education Program and ICU Patients
The aim of this clinical trial is to find out whether a synchrony-optimized education program for non-invasive ventilation (NIV) can help ICU patients use their ventilator more effectively and improve their comfort, symptoms, and…
- Conditions
- Ventilator Associated Events, Asynchrony, Patient-Ventilator, Intensive Care (ICU), Noninvasive Ventilation
- Trial name
- NCT07291622
- Testing
- SYNC-NIV
- Volunteers
- 92 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Ventilator Weaning, Airway Extubation
Can a Pain Monitor Predict When Postoperative Intensive Care Unit Patients Are Ready to Breathe on Their Own? A Pilot Study
The goal of this observational study is to learn if a chest monitor that tracks heart rhythm can help predict whether adults on a breathing machine after surgery will be able to breathe on their own once the breathing tube is…
- Conditions
- Ventilator Weaning, Airway Extubation, Respiration, Artificial
- Trial name
- NCT07771101
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Seoul National University Hospital
Intubated Patient Requiring a Gastric Tube
Impact of the Choice of Gastric Tube Placement Sites on the Incidence of Ventilator Associated Pneumonia
In intensive care, many gastric tubes are inserted on a regular basis. There are different practices in terms of the location of the gastric tube.
- Trial name
- SONG (NCT05915663)
- Testing
- nasogastric tube and orogastric tube, orogastric tube and nasogastric tube
- Where
- 16 sites in France
- Volunteers
- 2,400 people
- Sponsor
- Centre Hospitalier le Mans
Patient-Ventilator Asynchrony, Mechanical Ventilation Complication
Nurse Education to Reduce Patient-Ventilator Asynchrony in the PICU
A prospective cluster-randomized quality improvement trial was conducted to evaluate whether a structured nurse education program on ventilator waveform interpretation and alarm management reduces patient-ventilator asynchrony in…
- Conditions
- Patient-Ventilator Asynchrony, Mechanical Ventilation Complication, Nurse Education
- Trial name
- NCT07273487
- Testing
- Nurse Education on Ventilator Waveform and Alarm Management
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Dr. Behcet Uz Children's Hospital
İntensive Care, Nursing
The Effect of Reiki on Pain, Anxiety and Haemodynamic Parameters in Patients Receiving Mechanical Ventilator Support
Patients receiving mechanical ventilation (MV) support in intensive care units (ICU) may have some negative experiences. The most common of these are problems such as pain, agitation, anxiety, deterioration in comfort, dry mouth…
- Conditions
- İntensive Care, Nursing, Reiki
- Trial name
- NCT06526949
- Testing
- Reiki
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Yalova
Intensive Care Patients on a Ventilator
Safety of the Automatic Respiration Transfer System- Timer
The Israel Terminally Ill Law, 2005 allows patients who are terminally ill and ventilated to have their ventilator placed on a timer which at a specific time in the future stops the ventilator, maintains the patient on positive…
- Trial name
- Timer (NCT01735292)
- Testing
- Automatic Respiration Transfer System- Timer
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Hadassah Medical Organization
Ventilator-free Days, Quality of Breathing
Effect of Automated Closed-Loop Ventilation Versus Conventional Ventilation on Duration and Quality of Ventilation
INTELLiVENT-Adaptive Support Ventilation (ASV) is a fully automated closed-loop mode of mechanical ventilation available on commercial ventilators.
- Trial name
- ACTiVE (NCT04593810)
- Testing
- INTELLiVENT-ASV, CONVENTIONAL VENTILATION
- Where
- 10 sites in Italy, Netherlands
- Volunteers
- 1,201 people
- Sponsor
- Prof. Dr. Marcus J. Schultz
Mechanical Ventilation Complication
Assessing Gas Exchange in Intensive Care Patients on a Ventilator
In an attempt to standardise the degree of impairment of gas exchange in the lungs of ICU patients a number of indices of oxygen exchange have been developed.
- Trial name
- NCT02599350
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Aberdeen
Intensive Care Units, Neonatal, Misadventures to Patients During Surgical and Medical Care
SEPREVEN: a Stepped-wedge Randomised Controlled Trial
Adverse events are frequent in Neonatal Intensive Care Units' (NICU) patients and account for a high morbidity and mortality. Possible severe adverse events are central line associated bloodstream infections (CLABSI), ventilator…
- Conditions
- Intensive Care Units, Neonatal, Misadventures to Patients During Surgical and Medical Care, Catheter-related Bloodstream Infection (CRBSI) Nos, Quality of Healthcare
- Trial name
- SEPREVEN (NCT02598609)
- Testing
- Education program for NICU caregivers
- Where
- 12 sites in France
- Volunteers
- 8,000 people
- Sponsor
- Dr Caeymaex Laurence
Mechanical Ventilation
Effect of Transition From Mechanical Ventilation to Spontaneous Breathing on Intraocular Pressure in ICU (VENT-IOP)
This prospective, single-center observational study aims to evaluate the acute effects of transitioning from mechanical ventilation to spontaneous breathing on intraocular pressure (IOP) in intensive care unit patients.
- Trial name
- VENT-IOP (NCT07188922)
- Testing
- Non-invasive intraocular pressure measurement during ventilator weaning Description: Intraocular pressure will be measured using a portable non-invasive tonometer before and after the transition from
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Sevim Şenol Karataş
Intensive Care Patients, Relatives
Family Involvement in ICU
The aim of this prospective cohort study was to investigate the effect of the time spent with relatives of patients treated in a tertiary intensive care unit on patient outcomes.
- Conditions
- Intensive Care Patients, Relatives, Delirium in the Intensive Care Unit, Sedatives
- Trial name
- NCT06770751
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people
- Sponsor
- Istanbul University - Cerrahpasa
Airway Extubation
Maximum Expiratory Pressure in Induced Cough as a Predictor of Extubation Failure
Clinical trial for the evaluation of diagnostic tests. The sample was composed of adults under mechanical ventilation who passed the spontaneous breathing trial and was ready to be extubated.
- Trial name
- NCT04356625
- Testing
- MEPic
- Where
- Argentina
- Volunteers
- 80 people
- Sponsor
- Hospital Nacional Profesor Alejandro Posadas