Clinical trials: Intensive Care Pediatric
Weaning Failure
Interest of High Flow Nasal Cannula Oxygen Therapy in Pediatric Intensive Care Unit
monocentric randomized controlled trial starting from Mars 2017, recruitment is still ongoing. Patients aged between 0-45 days needing mechanical ventilation (MV) with tracheal intubation were included random assignation in two…
- Trial name
- NCT03505814
- Testing
- High Flow Nasal Cannula Oxygen therapy (OPTIFLOW®), Conventional oxygen therapy
- Where
- Tunisia
- Volunteers
- 126 people
- Sponsor
- Hôpital d'enfants Béchir-Hamza
ARDS, Human, Respiratory Failure
Driving Pressure and Mortality: in the Pediatric Intensive Care Unit (PICU)
Respiratory failure is one of the most common causes of both hospitalization and mortality in patients in the pediatric intensive care unit (PICU).
- Trial name
- NCT04419376
- Testing
- driving pressure
- Where
- Turkey (Türkiye)
- Volunteers
- 116 people
- Sponsor
- Dr. Behcet Uz Children's Hospital
Intensive Care Pediatric
Oxy-PICU Neurodevelopmental Follow-up Study
Background to the research: Each year around 20,000 children are admitted to paediatric intensive care units (PICUs) in the UK. Of these children, ~75% will receive support from a breathing machine (or ventilator) in combination…
- Trial name
- Oxy-PICU ND (NCT06734715)
- Testing
- Conservative oxygenation, Liberal oxygenation
- Volunteers
- 556 people
- Sponsor
- Intensive Care National Audit & Research Centre
Mechanical Ventilation Complication
Reduce Pediatric Sedation to Reduce Mechanical Ventilation Complication in ICU
Mechanical ventilation is a common procedure used in pediatric intensive care units (ICU). Its use requires almost always the establishment of a sedation.
- Trial name
- PEDIASED (NCT02040168)
- Where
- France
- Volunteers
- 106 people
- Sponsor
- Nantes University Hospital
Delirium
Delirium Detection in Pediatric Intensive Care Unit Through a French Translation of the CAPD : a French Monocentric Observational Study
The purpose of this study is to introduce delirium detection and try to determine the prevalence of delirium in Pediatric Intensive Care Unit (PICU) using a validated tool : the Cornell Assessment of Pediatric Delirium (CAPD) for…
- Trial name
- DeliReP (NCT04954261)
- Testing
- CAPD
- Where
- France
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pediatric Respiratory Diseases, Respiratory Failure
Use of Lung Ultrasound to Diagnose the Etiology of Respiratory Failure in a PICU.
The purpose of this study is to determine the utility of point-of-care lung ultrasound (POC-LUS) in identifying the etiology of acute respiratory failure in pediatric patients admitted to the pediatric intensive care unit.
- Trial name
- NCT03744169
- Testing
- Lung ultrasound, Clinical exam, Chest x-ray
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- University of Wisconsin, Madison
Mechanical Ventilation, Children
Pediatric Ventilatory Care in Finland 2010
This observational study includes questionnaires send to doctors in all units treating pediatric patients with mechanical ventilation in Finland.
- Conditions
- Mechanical Ventilation, Children, Neonates, Pediatric Intensive Care
- Trial name
- NCT01348295
- Testing
- Observation
- Where
- Finland
- Volunteers
- 210 people
- Sponsor
- University of Oulu
Sleep
Sleep in Pediatric Intensive Care Patients
This research will be carried out experimentally in order to investigate the Effect of Sleep Band and White Noise Use on the Time to Sleep in Pediatric Intensive Care Patients aged 3-12 months.
- Trial name
- NCT05432076
- Testing
- Sleep Band and White Noise
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Ebru Kilic
Limited English Proficiency
Family-Initiated Interpretation in the PICU
The goal of this study is to compare interpreter use rates before and after allowing non-English speaking families to call an interpreter themselves.
- Trial name
- NCT05791240
- Testing
- Family Initiated Interpretation
- Where
- United States
- Volunteers
- 292 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Conscious Sedation
Efficiency of Ventilation During Conscious Sedation in the Pediatric Intensive Care Unit
Pediatric patients admitted to the intensive care unit and requiring conscious sedation for minor surgical procedures are at risk to hypoventilate and retain CO2. The rise in CO2 levels is not well described and unpredicted.
- Trial name
- NCT01287572
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Acute Lymphoblastic Leukemia (ALL), Critical Illness
Animal Assisted Interactions With Animal Robot in the Intensive Care Unit (ICU)
The purpose of this study is to: 1. Establish the feasibility and acceptability of a therapeutic robot, Paro, for critically ill patients admitted to the Pediatric Intensive Care Unit 2.
- Conditions
- Acute Lymphoblastic Leukemia (ALL), Critical Illness, Physical Therapy Modalities, Occupational Therapy
- Trial name
- PARO (NCT05075395)
- Testing
- PARO therapy seal
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Nebraska
Drug Therapy
Safety Analysis of Antimicrobial Pharmacotherapy in Intensive Care Unit at Pediatric Hospital
Changes in the metabolic ability of cytochrome P-450 during child development can affect both bioavailability and elimination depending on the involvement of intestinal and hepatic metabolic processes.
- Trial name
- NCT04141657
- Testing
- Pharmacogenetic test
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- Anna Vlasova
Tranexamic Acid, Pulmonary Hemorrhage
Impact of Inhaled Tranexamic Acid in Pulmonary Hemorrhage in Pediatric Intensive Care Unit
This study aimed to detect the impact of inhaled Tranexamic acid® in pulmonary hemorrhage in pediatric intensive care unit.
- Conditions
- Tranexamic Acid, Pulmonary Hemorrhage, Pediatric, Intensive Care Unit
- Trial name
- NCT07481682
- Testing
- Tranexamic acid + conventional therapy., Tranexamic acid
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Tanta University
Failed Conscious Sedation During Procedure
The Efficacy and the Safety of Dexmedetomidine Sedation on the Pediatric Intensive Unit(PICU) Patients.
To observe the efficacy and safety of dexmedetomidine sedation on the patients admitted to the pediatric intensive care unit after surgery.
- Trial name
- NCT02296073
- Testing
- Midazolam, Dexmedetomidine, Fentanyl
- Volunteers
- 120 people
- Sponsor
- Anhui Provincial Children's Hospital
PICU, Nurses
Smart Mind Maps in Promoting Safe Administration of High-Alert Medications
In PICU setting, drug administration, monitoring, and prescribing errors made up most cases (54%) of MEs . Emphasizes these issues requires a multifaceted approach, including staff training, creation of innovative cognitive…
- Trial name
- HAMs- PICU (NCT07320196)
- Testing
- smart mind mapsde
- Volunteers
- 70 people
- Sponsor
- Mansoura University
Emotion Journal, Pediatric Intensive Care
Emotion Diary Application
Pediatric patients, hospitalization in a pediatric intensive care unit (PICU) is not merely a situation requiring physical treatment, but also an experience that has significant psychosocial effects.
- Conditions
- Emotion Journal, Pediatric Intensive Care, Emotion Regulation, Emotional Awareness
- Trial name
- NCT07860190
- Testing
- Emotion Diary Administration
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Gazi University
Pediatric Respiratory Diseases, Bronchiolitis
Assessment of NeuroBOX and NeuroPAP in Infants.
Non-invasive ventilation (NIV, delivered via a mask or cannulas) permits to reduce the need for tracheal intubation in infants who needs a ventilatory support.
- Conditions
- Pediatric Respiratory Diseases, Bronchiolitis, Infant Respiratory Distress Syndrome
- Trial name
- NeuroPap2 (NCT03650478)
- Testing
- NeuroPAP ventilation (2h) and NeuroBox monitoring (23h), NeuroPAP ventilation (4h) and NeuroBox monitoring (25h)
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- St. Justine's Hospital
Posttraumatic Stress Disorder, Parents
Posttraumatic Stress Disorder in Parents and Children After Discharge From the Pediatric Intensive Care Unit
Background: If disorders that occur immediately after a trauma are not treated, they may become chronic and turn into severe health problems.
- Conditions
- Posttraumatic Stress Disorder, Parents, Children, Only
- Trial name
- PTSD (NCT05186844)
- Testing
- survey application
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Pediatric Respiratory Diseases
Outcome of Patients Admitted to Pediatric Intensive Care for Acute Respiratory Failure
This study aims to assess the quality of life of patients six months after admission to a pediatric intensive care unit for acute respiratory failure.
- Trial name
- NCT06470932
- Testing
- Follow-up consult
- Volunteers
- 50 people
- Sponsor
- University Hospital, Grenoble
Communication, Critical Illness
Improving Family Meetings in the Pediatric Cardiac Intensive Care Unit
This study aims to improve communication between medical teams, patients, and families in the pediatric cardiac intensive care unit.
- Trial name
- NCT03749330
- Testing
- CICU Team And Loved Ones Communicating (CICU TALC)
- Where
- United States
- Volunteers
- 451 people
- Sponsor
- Children's Hospital of Philadelphia