Clinical trials: Intensive Care Psychosis
Delirium, Critical Illness
Haloperidol for Delirium in Adult Critically Ill Patients
The EuRIDICE trial will study whether haloperidol as a first line treatment for ICU delirium reduces delirium duration (and severity).
- Conditions
- Delirium, Critical Illness, Intensive Care Psychosis, Cognitive Impairment
- Trial name
- EuRIDICE (NCT03628391)
- Testing
- Haloperidol
- Where
- 8 sites in Netherlands
- Volunteers
- 142 people
- Sponsor
- Erasmus Medical Center
Disorder; Mental, Sedative, Depressed Level of Consciousness
Use of Bispectral Index Monitoring to Detect Deep Sedation in Mechanically Ventilated Patients: Validity Study
In the previous study, the investigators obtained the cutoff value of Bispectral Index to detect early deep sedation in patients with mechanical ventilation.
- Conditions
- Disorder; Mental, Sedative, Depressed Level of Consciousness, Mechanical Ventilation Complication, Psychosis Associated With Intensive Care
- Trial name
- NCT02439840
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Capital Medical University
Severe Mental Illness, Severe Mental Disorder
Outcome of Patients With Severe Mental Illness in the Intensive Care Unit
Severe mental illnesses (SMIs), such as major depression, schizophrenia, and bipolar disorder, carry a significant prevalence among patients admitted to the intensive care unit (ICU), estimated at an average of 19%.
- Trial name
- REPSYRE (NCT07705802)
- Testing
- Observational follow-up
- Where
- 30 sites in France
- Volunteers
- 2,000 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Premature Infant, Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse)
Preventing Vulnerable Child Syndrome in the NICU With Cognitive Behavioral Therapy (PreVNT Trial)
This study is being done to see if outcomes for both a premature infant's parents and the infant born prematurely who have spent time in the neonatal intensive care unit (NICU) can be improved through parent cognitive behavioral…
- Conditions
- Premature Infant, Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Development, Child, Parent-Child Relations
- Trial name
- PreVNT (NCT03906435)
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Artificial Intelligence, Septic Shock
Artificial Intelligence for Sepsis Prediction in ICU
The development of sepsis prediction model in line with Chinese population, and extended to clinical, assist clinicians for early identification, early intervention, has a good application prospect.
- Conditions
- Artificial Intelligence, Septic Shock, Intensive Care Unit Psychosis
- Trial name
- AICUSepsis (NCT04913181)
- Testing
- Artificial intelligence sepsis prediction model
- Volunteers
- 2,000 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Acute Mechanical Ventilatory Failure, Psychosis Associated With Intensive Care
Efficacy of Closed-loop Ventilation to Reduced Sleep Disorders
Sleep's deficiencies are very common in intensive care. Mechanical ventilation is a known factor in this deterioration.The investigators hypothesize that close-loop ventilation mode (Intellivent-ASV) is able to minimize sleep…
- Trial name
- SleepICU (NCT02095496)
- Testing
- Intellivent-ASV, Conventional ventilation
- Where
- Belgium
- Volunteers
- 16 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Intensive Care Psychosis
Follow-up in Pediatric Intensive Care Unit
Background In developed countries, mortality rates in pediatric intensive care units (PICUs) are around 4% and thus, most children admitted to these units survive.
- Trial name
- APRELAREA (NCT06363344)
- Testing
- Questionnaires : PHQ-9 (Kroenke, 2001), the PSC (Sheldrick, 2012), the ASQ-SE (Squires, 2015), the PedsQL (Varni, 1999)
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Delirium
The Validity of the Thai Version of the Confusion Assessment Method
The purpose of this study is to determine the validity and reliability of the Thai version of the Confusion Assessment Method for the intensive care (CAM-ICU) in the elderly and the prevalence of delirium in elderly.
- Trial name
- NCT01267630
- Where
- 3 sites in Thailand
- Volunteers
- 70 people
- Sponsor
- Chiang Mai University
Disorder; Mental, Sedative, Depressed Level of Consciousness
BIS Monitoring to Detect Deep Sedation
Studies have shown that prolonged deep sedation is associated with adverse clinical outcomes in adult intensive care unit (ICU) patients.
- Conditions
- Disorder; Mental, Sedative, Depressed Level of Consciousness, Mechanical Ventilation Complication, Psychosis Associated With Intensive Care
- Trial name
- NCT02203344
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Capital Medical University
Sleep Deprivation, Intensive Care Psychosis
Exogenous Melatonin in Intensive Care Unit Chronodisruption
To this day, a small number of studies have evaluated the effect of melatonin on the modifications of the characteristics of sleep in critical care units, with mostly a small studied population.
- Trial name
- EMIC (NCT03708341)
- Testing
- Melatonin 5 mg
- Where
- Lebanon
- Volunteers
- 98 people
- Sponsor
- Saint-Joseph University