Clinical trials: Intensive Care Unit
Critical Illness
Code Status Video in the Intensive Care Unit: Video Assisted Patient Education
This is a single-center, randomized control trial of a code status video as an educational tool in the intensive care unit. Subjects are stratified by patient or surrogate and are randomized to either watch an educational video…
- Trial name
- NCT01610076
- Testing
- Code Status Video
- Where
- United States
- Volunteers
- 208 people
- Sponsor
- Mayo Clinic
Blood Pressure
Intraosseous Pressure Monitoring in Intensive Care Unit Patients
In emergency situations, access to the venous system is essential in order to administer fluids and medication and to monitor patients.
- Trial name
- NCT02059928
- Testing
- Intraosseous Device
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- HealthPartners Institute
Hyperglycemia
Feasibility Study to Evaluate Safety and Device Performance of the Hospital Glucose Management System (HGMS)
The purpose of this study is to assess safety and device performance of the Medtronic Hospital Glucose Management System (HGMS) for up to 72-hours.
- Trial name
- MAHI (NCT01763567)
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Medtronic MiniMed, Inc.
Depression
Preventing Depression in People Receiving Mechanical Ventilation in an Intensive Care Unit
This study will determine the effectiveness of antidepressant medication in preventing depression and improving recovery in people who have been supported by mechanical ventilators in an intensive care unit (ICU).
- Trial name
- NCT00872027
- Testing
- Escitalopram
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Minnesota
Cardiac Disease, Cardiac Ischemia
Assessment of Patients Undergoing Cardiac Surgery and Admitted to the Intensive Care Unit
The objective of this study is to investigate the incidence of death and early postoperative complications, identify potential risk factors, and examine the demographic characteristics of patients and epidemiology of…
- Conditions
- Cardiac Disease, Cardiac Ischemia, Cardiac Valve Disease
- Trial name
- BraSIS-2 (NCT06154473)
- Testing
- Open heart surgery group., Percutaneous cardiovascular surgery group.
- Where
- Brazil
- Volunteers
- 528 people
- Sponsor
- Hospital Israelita Albert Einstein
Methicillin-resistant Staphylococcus Aureus
Cluster Randomized Trial of Hospitals to Assess Impact of Targeted Versus Universal Strategies to Reduce Methicillin-resistant Staphylococcus Aureus (MRSA) in Intensive Care Units (ICUs)
The Randomized Evaluation of Decolonization versus Universal Clearance to Eliminate MRSA (REDUCE MRSA) Trial is a cluster randomized trial of the comparative effectiveness of three strategies to prevent methicillin-resistant…
- Trial name
- REDUCE-MRSA (NCT00980980)
- Testing
- Chlorhexidine bath and nasal mupirocin
- Where
- 42 sites in United States
- Volunteers
- 74,256 people
- Sponsor
- Harvard Pilgrim Health Care
Critically Ill
Is There Any Correlation Between Respiratory Variation Ratios of Internal Jugular Vein and Inferior Vena Cava?
Intravascular volume assesment is important for the management of the patients in the intensive care unit. Respiratory variation ratio of the inferior vena cava (IVC) can be determined by ultrasonography (USG) and is a useful…
- Trial name
- NCT04173741
- Testing
- USG measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Hacettepe University
ICU Acquired Weakness (ICUAW)
Feasibility and Safety of Digital Rehab Platform for Bedridden Patients
Study Title Rehabilitation Program for Bedridden Patients Using Digital Devices Study Purpose This study aims to evaluate the effectiveness of a rehabilitation program using digital devices and apps for bedridden patients in a…
- Trial name
- NCT06849765
- Testing
- Rehabilitation
- Where
- South Korea
- Volunteers
- 25 people
- Sponsor
- Asan Medical Center
Cerebral Palsy, Hypoxic-Ischemic Encephalopathy
Therapeutic Intervention Supporting Development From NICU to 6 Months for Infants Post Hypoxic-Ischemic Encephalopathy
The purpose of this study is to evaluate the feasibility and begin to evaluate the effect of a sensorimotor intervention (SMI) provided in the first 6 months of life for infants with hypoxic-ischemic encephalopathy.
- Trial name
- NCT05130528
- Testing
- Sensorimotor Intervention
- Where
- 2 sites in United States
- Volunteers
- 11 people
- Sponsor
- University of Southern California
Critical Illness, Fever
Safety and Efficacy of Acetaminophen in the Intensive Care Unit.
The intensive care unit (ICU) team needs to know what effects acetaminophen has in critically ill patients. Acetaminophen is better known as Tylenol. It is the drug given to reduce fever.
- Trial name
- SEA-ICU (NCT02280239)
- Testing
- Acetaminophen
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- University of British Columbia
General Surgery
Inflammation and Postoperative Tramadol Analgesia
Patients will be admitted in the intensive care unit after major abdominal surgery. All patients will receive 100 mg of tramadol intravenously every 6 hours.
- Trial name
- NCT04330157
- Where
- Croatia
- Volunteers
- 50 people
- Sponsor
- Osijek University Hospital
Delirium, Cognitive Impairment
Family Automated Voice Reorientation Study
This randomized clinical trial tests a cognitive reorientation intervention to prevent delirium in the intensive care unit using scripted audio messages, recorded by the patient's family and played at hourly intervals during…
- Conditions
- Delirium, Cognitive Impairment, Health, Subjective, Sleep
- Trial name
- FAVoR (NCT03128671)
- Testing
- FAVoR Intervention
- Where
- 3 sites in United States
- Volunteers
- 178 people
- Sponsor
- University of Miami
Infection Control
Enhanced Room Cleaning in Intensive Care Units to Reduce Gown and Glove Contamination With Multi-drug-resistant Bacteria
The purpose of this study is to determine whether extra cleaning of frequently-contaminated surfaces in intensive care rooms is effective in preventing contamination of disposable isolation gowns and gloves with multi-drug…
- Trial name
- NCT01481935
- Testing
- Enhanced cleaning of surfaces in ICU rooms
- Where
- United States
- Volunteers
- 190 people
- Sponsor
- University of Maryland, Baltimore
High Flow Nasal Cannula
HFNC Flow Titration and Effort of Breathing in the PICU
High-flow nasal cannula (HFNC) is a method of non-invasive respiratory support used to decrease the effort of breathing (EOB) in patients with a wide variety of respiratory diseases in the pediatric intensive care unit.
- Trial name
- HFNCandEOB (NCT02793674)
- Testing
- Fisher & Paykel high flow nasal cannula, Vapotherm high flow nasal cannula
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Children's Hospital Los Angeles
Acute Respiratory Failure Requiring Mechanical Ventilation
Eye-Control Trial: Wearable Eye-Tracking Device as Means of Communication
The purpose of this study is to evaluate the feasibility of use of a wearable communication device for critically ill patients who are admitted to the intensive care unit (ICU) and mechanically ventilated.
- Trial name
- NCT04582149
- Testing
- EyeControl Eye-tracking Device
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Emory University
Gastrointestinal Bleeding, Stress Ulcers
Stress Ulcer Prophylaxis in the Intensive Care Unit
Stress ulcer prophylaxis (SUP) is standard of care in the intensive care unit (ICU), however the quantity and quality of evidence is low and potential harm has been reported.
- Trial name
- SUP-ICU (NCT02467621)
- Testing
- Pantoprazole, Saline (0.9%)
- Where
- 33 sites in Denmark, Finland and 4 more
- Volunteers
- 3,350 people
- Sponsor
- Dr. Morten Hylander Møller
Erythema, Edema
Safety and Feasibility of Prima-Temp Thermometer Patch
The purpose of this study is to test the safety and feasibility of the Prima-Temp Thermometer Patch in determining baseline temperatures of research subjects in a hospital intensive care unit (ICU).
- Conditions
- Erythema, Edema, Papules White, Eruption
- Trial name
- Prima-Temp (NCT01587014)
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Poudre Valley Health System
Sedation
Efficacy and Safety of Inhaled Isoflurane Delivered Via the Sedaconda ACD-S Compared to Intravenous Propofol for Sedation of Mechanically Ventilated Intensive Care Unit Adult Patients (INSPiRE-ICU2)
This is a study to compare safety and efficacy of inhaled isoflurane administered via the Sedaconda ACD-S device system versus intravenous propofol for sedation of mechanically ventilated patients in the Intensive Care Unit (ICU)…
- Trial name
- INSPiRE-ICU2 (NCT05327296)
- Testing
- Isoflurane, Propofol
- Where
- 16 sites in United States
- Volunteers
- 282 people
- Sponsor
- Sedana Medical
Premature Infant Disease, Family Research
PREEMIE PROGRESS: A Family Management Program for Parents of Preterm Infants
The purpose of this study is to refine and pilot test a mobile health (mHealth), video-based family management program for parents of preterm infants hospitalized in the Neonatal Intensive Care Unit (NICU).
- Conditions
- Premature Infant Disease, Family Research, Parent-Child Relations, Self Efficacy
- Trial name
- NCT04638127
- Testing
- PREEMIE PROGRESS, Attention Control
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Critical Illness
Family Satisfaction (FS) in the Intensive Care Unit
There is increasing awareness that high-quality care in the intensive care unit also includes care of visiting family members according to their needs.
- Trial name
- NCT01449734
- Where
- Germany
- Volunteers
- 217 people
- Sponsor
- Center for Sepsis Control and Care, Germany