Clinical trials: Intensive Care Unit (ICU)
Hypertension, Pulmonary, Right Ventricular Overload
The Prevalence of Pulmonary Hypertension in Patients With COVID-19.
The virus infection Covid-19 fills our hospitals and intensive care departments in a very unique way and there is a lack of essential insight into the pathophysiology of the disease.
- Conditions
- Hypertension, Pulmonary, Right Ventricular Overload, COVID
- Trial name
- NCT04459364
- Where
- Sweden
- Volunteers
- 67 people
- Sponsor
- Attgeno AB
Central Line-associated Bloodstream Infection (CLABSI)
Port Protectors for Prevention of CLABSIs in Respiratory Semi-intensive Care Unit
Central Line-Associated BloodStream Infections (CLABSIs) are responsible for many deaths in the United States annually. Several collaboratives have demonstrated the preventability of these infections.
- Trial name
- NCT03486093
- Testing
- Training and retraining to GAVECELT "bundle" recommendations plus port protector, Training and retraining to GAVECELT "bundle" recommendations
- Volunteers
- 132 people
- Sponsor
- Catholic University of the Sacred Heart
To Assess the Tissular and Plasma Kinetics of Ertapenem
Prospective, Open-label Study of Pharmacokinetics of Ertapenem in the Muscle Using Microdialysis in Mechanically Ventilated Intensive Care Unit Patients, Treated or Not by Norepinephrine
Goal of study: To assess the tissular and plasma kinetics of ertapenem; To determine the optimal dosages in the patients according to norepinephrine administration: to assess muscular diffusion of free form of ertapenem after…
- Trial name
- NCT00489138
- Testing
- Ertapenem
- Where
- France
- Volunteers
- 9 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Malnutrition, Critical Illness
Anabolic Steroids for Nutritional Rehabilitation of Critically Ill Patients
This prospective, double-blinded study will determine the feasibility of determining the efficacy of a weekly intramuscular injection of nandrolone (an anabolic steroid) in malnourished ICU patients.The data from this study will…
- Trial name
- NCT00242463
- Testing
- Nandrolone (anabolic steroid)
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Delirium, Anxiety
Patient- and Family-centred Care in the Adult Intensive Care Unit: a Feasibility Study
Background: In the intensive care unit (ICU), delirium in patients and long-term mental health challenges in both patients and their family members are highly prevalent.
- Conditions
- Delirium, Anxiety, Post Intensive Care Unit Syndrome, Post Intensive Care Unit Syndrome Family
- Trial name
- FAM-ICU (NCT06974214)
- Testing
- FAM-ICU
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Herlev Hospital
ECMO Outcomes, Respiratory Failure (Pediatric Patients)
ECMO Use in Pediatric Oncology and HSCT Patients: A Descriptive and Comparative Analysis
This was an observational study, with a descriptive and comparative portion. The descriptive analysis, a large single center experience, examined bleeding complications, infectious rates, and survival outcomes in patients under…
- Conditions
- ECMO Outcomes, Respiratory Failure (Pediatric Patients), Malignancies, Hematologic, Solid Tumor Malignancies
- Trial name
- NCT07712835
- Testing
- Extracorporeal membrane oxygenation (ECMO)
- Volunteers
- 22 people
- Sponsor
- Children's Mercy Hospital Kansas City
Extreme Prematurity, Neurodevelopmental Abnormality
Osteopathic Manipulative Medicine to Reduce Developmental Delays
This randomized clinical trial seeks to determine if osteopathic manipulative medicine (OMM) increases the likelihood of improved neurodevelopmental outcomes as estimated by the Test of Infant Motor Performance (TIMP).
- Trial name
- NCT04652063
- Testing
- Osteopathic Manipulative Medicine
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Prematurity, Low Birth Weight Neonates
Metagenomic & Metabolomic Study: Bifidobacterium Probiotic Effects on Gut Microbiota & SCFA in Preterm NICU Infants
One million premature babies die due to prematurity complications, contributing the most to the causes of death in children under 5 years old.
- Trial name
- NCT07213414
- Testing
- Probiotics
- Where
- 3 sites in Indonesia
- Volunteers
- 72 people
- Sponsor
- Hasanuddin University
Premature Infant Disease
A Randomized Controlled Trial to Evaluate the Effect of White Noises and Parental Voices As Protectors Against Noise Damage in a Neonatal Intensive Care Unit
The goal of this Randomized Controlled Trial is to test the efficacy of listening to white noises and parental voices against environmental noise damage in premature babies admitted to the Newborn Intensive Care Unit.
- Trial name
- NCT06150404
- Testing
- White Noises and Maternal and/or Paternal voices
- Where
- Italy
- Volunteers
- 11 people
- Sponsor
- Istituto Giannina Gaslini
Nutritional Support, Intensive Care Unit
Evaluation of Nutritional Practices in the Critical Care
Background: The adequacy of the artificial Nutritional Support (NS) in the critical care patient has implications in morbidity and prognosis.
- Conditions
- Nutritional Support, Intensive Care Unit, Critical Illness
- Trial name
- ENPIC (NCT03634943)
- Testing
- Patients with Nutritional Support
- Where
- 43 sites in Spain
- Volunteers
- 642 people
- Sponsor
- Hospital Universitari de Bellvitge
Acute Coronary Syndromes (ACS)
Effect of Guided Imagery on Sleep Quality, State Anxiety, and Comfort in Patients With Acute Coronary Syndrome
The goal of this randomized controlled trial is to determine whether guided imagery, when added to routine care, can reduce state anxiety and improve sleep quality and comfort in adults with acute coronary syndrome who are being…
- Trial name
- NCT07794358
- Testing
- Guided Imagery
- Volunteers
- 64 people
- Sponsor
- Afyonkarahisar Health Sciences University
Poor Quality Sleep, Sleep Deprivation
The Comparison of Dexmedetomidine and Midazolam for the Sleep in Intensive Care Unit
The investigators are going to compare the sleep quality and quantity between dexmedetomidine group and midazolam group using 24 hour polysomnography in critically ill patients.
- Conditions
- Poor Quality Sleep, Sleep Deprivation, Sleep Arousal Disorders, Delirium
- Trial name
- NCT01966315
- Where
- South Korea
- Volunteers
- 5 people
- Sponsor
- Seoul National University Hospital
Delirium in the Intensive Care Unit
Nurse-Led Implementation of the ABCDEF Bundle
This study evaluated the effectiveness of a nurse-led implementation of the ABCDEF bundle, an evidence-based, interprofessional care framework, in the prevention and management of delirium among Intensive Care Unit (ICU)…
- Trial name
- NCT07054268
- Testing
- Nurse-Led ABCDEF Bundle Implementation
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Helwan University
Exposure to Secondhand Smoke in Neonatal Infants
Motivational Incentives to Reduce Secondhand Smoke in NICU Infants' Homes
A randomized, controlled, parallel group design will be used to test whether a Secondhand Smoke Exposure program initiated in the hospital and completed in the home using motivational interviewing plus motivational incentives…
- Trial name
- NCT01726062
- Testing
- Motivational Interviewing plus Incentives, Conventional Care (CC)
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Intensive Care Unit Syndrome
Hemodynamic Impact of the Administration of PAracetamol in Patients Hospitalized in the Intensive Resuscitation Medicine Department [PAREA]
Paracetamol is commonly used in case of pain or fever. Few previously clinical studies has highlighted an arterial hypotension linked to intravenous administration of paracetamol.
- Trial name
- PAREA (NCT06430697)
- Testing
- paracetamol administration
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Blood Glucose Monitoring in Medical ICU
Comparative Study of GlySure Continuous Intra-vascular Glucose Monitoring and Intermittent Monitoring in Medical ICU
It has been shown that close control of blood glucose levels in the intensive care unit patient has benefits for patient morbidity and mortality rates as well as an impact upon discharge times.
- Trial name
- MICU (NCT02142088)
- Testing
- GlySure Intravascular Continuous glucose monitoring sensor
- Volunteers
- 60 people
- Sponsor
- GlySure
Burns
Protocol of Management of Major Pediatric Burn in Intensive Care Unit
Decrease mortality and morbidity in major pediatric burns
- Trial name
- NCT04192942
- Testing
- protocol of management of major burn in intensive care unit
- Volunteers
- 100 people
- Sponsor
- Assiut University
Sepsis, Sepsis and Septic Shock
Role of Transposable Elements in Septic Immune Aging
The goal of this observational study is to learn about how transposable element levels affect the patient outcomes in sepsis. The main questions it aims to answer is: 1.
- Conditions
- Sepsis, Sepsis and Septic Shock, Sepsis With Multiple Organ Dysfunction (MOD), Sepsis With Acute Organ Dysfunction
- Trial name
- SITE (NCT06809868)
- Testing
- RNA and DNA Sequencing
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Sepsis - to Reduce Mortality in the Intensive Care Unit
Efficacy and Safety of Oral Nicotinamide as an Adjunctive Therapy in Patients With Sepsis
Sepsis is a severe, life-threatening condition caused by an abnormal host response to infection, which includes systemic inflammation, oxidative stress, and increasing organ dysfunction.
- Trial name
- NCT07655791
- Testing
- Nicotinamide 1000 mg
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Intensive Care Unit Delirium
PRE-DELIRIC Prediction Model Plus SMART Care to Reduce the Incidence of Delirium in ICU Patients
Delirium is a severe acute brain dysfunction characterised by sudden confusion, inattention and fluctuating level of consciousness, which mainly affects intubated intensive care patients.
- Trial name
- NCT06279390
- Where
- Taiwan
- Volunteers
- 381 people
- Sponsor
- National Taiwan University Hospital