Clinical trials: Intensive Care Unit (ICU) Patients
Critical Illness, Surgery
Gastric US in ICU Patient
This is a case series study using gastric ultrasound in critically ill patients to quantify gastric residual volumes to compare the efficacy of different NPO protocols.
- Conditions
- Critical Illness, Surgery, Aspiration Pneumonia
- Trial name
- NCT05526105
- Testing
- Gastric Ultrasound
- Where
- United States
- Sponsor
- Dartmouth-Hitchcock Medical Center
Sepsis, Respiratory Failure
The Effect of Intensive Insulin Therapy in the Surgical Critical Care Unit
We sought to determine if there is a benefit to using an insulin drip to control hyperglycemia in the surgical critical care unit for patients who undergo general and vascular surgery.
- Conditions
- Sepsis, Respiratory Failure, Renal Failure, Surgical Site Infection
- Trial name
- NCT00282594
- Testing
- Novolin R (human recombinant Insulin)
- Where
- United States
- Volunteers
- 317 people
- Sponsor
- Genesys
Nosocomial Infection
Epidemiological Investigation of CRBSI, VAP, CAUTI in Chinese ICU
The current protocol desires to implement a large-multicenter observational study of hospital acquired infection in ICU in China.
- Trial name
- NCT01943331
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Southeast University, China
Continuous Glucose Measurement
A Comparative Study to Evaluate the Accuracy and Safety of the GlySure Continuous Intravascular Glucose Monitoring System Versus Intermittent Blood Glucose Monitoring
The purpose of this study is to evaluate the system performance of the GlySure Continuous Glucose Monitoring (CGM) system in patients admitted to the Surgical Intensive Care Unit.
- Trial name
- NCT01942902
- Testing
- Continuous Glucose Monitoring System
- Where
- 2 sites in India
- Volunteers
- 38 people
- Sponsor
- GlySure
Critical Illness, Stress Disorders, Traumatic, Acute
Intensiva 2.0: Improve the Communication Towards Families of Critically Ill Patients
The admission of a loved one in an ICU is a hard experience for family members. They frequently feel fear and grief, develop anxiety and depression symptoms, or even show some behaviors as this event was a real traumatic one…
- Conditions
- Critical Illness, Stress Disorders, Traumatic, Acute, Stress Disorders, Post-Traumatic
- Trial name
- Intensiva2 (NCT03438175)
- Testing
- Enhanced communication by brochure, website and posters
- Where
- Italy
- Volunteers
- 2,100 people
- Sponsor
- University of Milan
COVID-19
Evaluation of Safety & Efficacy of MIR 19 ® Inhalation Solution in Patients With Moderate COVID-19
This is Phase 2 multi-center controlled randomized study to assess the efficacy and safety of MIR 19® via 14 days of treatment of participants with symptomatic moderate COVID-19.
- Trial name
- NCT05184127
- Testing
- MIR 19 ®, Standard COVID-19 therapy
- Where
- Russia
- Volunteers
- 156 people
- Sponsor
- National Research Center - Institute of Immunology Federal Medical-Biological Agency of Russia
Serious Injury, Communication
A Communication Tool to Improve Communication in the ICU
The purpose of this study is to test the effectiveness of the Best Case/Worst Case-ICU communication tool on quality of communication, clinician moral distress, and ICU length of stay for older adults with serious traumatic…
- Trial name
- NCT05780918
- Testing
- Best Case/Worst Case-ICU Communication Tool
- Where
- 8 sites in United States
- Volunteers
- 7,320 people
- Sponsor
- University of Wisconsin, Madison
Critical Illness
Observational Cohort Study on the Use of Parenteral Nutrition and Clinical Outcomes in Adult Critically Ill Patients
The aim of this study is to characterise the use of clinical nutrition support, especially of parenteral nutrition that is administered directly into a vein, in adult patients with critical illness.
- Trial name
- NCT04143503
- Where
- 76 sites in Austria, Belgium and 9 more
- Volunteers
- 1,208 people
- Sponsor
- Fresenius Kabi
Quality of Life
Health-related Quality of Life and Nursing-sensitive Outcomes in Mechanically Ventilated Patients
This study will allow us to determine the perceived Health-Related Quality of Life (HRQL) a year after ICU discharge, and compare it with HRQL measured earlier on in the process, as well as analyse the negative experiences they…
- Trial name
- NCT02636660
- Volunteers
- 184 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Patients at the Intensive Care Unit (ICU)
The Effect of High Frequency Percussive Ventilation on Cerebral Tissue Oxygenation
Hypoxemia is commonly reported in patients admitted to the Intensive Care Unit (ICU) and may result from acute lung injury/acute respiratory distress syndrome (ALI/ARDS), sepsis, trauma and postoperative complications.
- Trial name
- NCT02545803
- Testing
- Near-Infrared Spectroscopy (NIRS)
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Hasselt University
Delirium, Respiratory Failure
How Your Patients' Non-REM Sleep Changes On Sedatives in the Intensive Care Units
The purpose of this study is to study the effect of two standard of care sedative medications on sleep stages and total sleep time.
- Trial name
- HYPNOS (NCT00826553)
- Testing
- Dexmedetomidine, GABA agonist
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Vanderbilt University Medical Center
the Maintenance of Normoglycemia, the Incidence of Ventilator Associated Pneumonia (VAP)
The Effect of Intensive Insulin Therapy
Aim. To determine whether the maintenance of normoglycemia decreases the incidence of ventilator associated pneumonia (VAP), reduces its treatment period and the length of stay in the intensive care unit. Methods.
- Conditions
- the Maintenance of Normoglycemia, the Incidence of Ventilator Associated Pneumonia (VAP), Treatment Period in the Intensive Care Unit
- Trial name
- NCT00447239
- Testing
- glucontrol (insulin therapy)
- Where
- Slovenia
- Volunteers
- 117 people
- Sponsor
- University Medical Centre Ljubljana
Subarachnoid Hemorrhage, Aneurysmal
Pronostic Factors in Elderly Patients Admitted to the Intensive Care Unit for Aneurysmal Subarachnoid Hemorrhage
Subarachnoid hemorrhage (SAH) represents a significant proportion of hemorrhagic strokes. Severe SAH in elderly patients is associated with poorer outcomes compared to younger cohorts.
- Trial name
- FAPPAR-HSA (NCT07508683)
- Where
- France
- Volunteers
- 170 people
- Sponsor
- Central Hospital, Nancy, France
Critical Illness, Transitions of Care
Evaluating the Effectiveness of an Electronic Medical Transfer Tool to Improve Communication During Transfers From ICU
The transfer of patients from the intensive care unit (ICU) to a medical or surgical hospital ward is a particularly high risk transfer that may expose patients to complications or adverse events if there are communication…
- Trial name
- NCT03590002
- Testing
- Electronic ICU Medical Transfer Tool
- Where
- 4 sites in Canada
- Volunteers
- 1,751 people
- Sponsor
- Henry T. Stelfox, MD PhD
Critical Illness, Hyperglycemia
Early Glucose States and 72-Hour Care-Metabolic Clusters in Critically Ill Patients
Blood glucose patterns during critical illness may change together with treatment, nutritional support, organ support, and the frequency of glucose monitoring.
- Trial name
- NCT07851545
- Testing
- Early glucose state, 72-hour integrated care-metabolic cluster
- Where
- China
- Volunteers
- 5,109 people
- Sponsor
- Shanghai Zhongshan Hospital
Early Acute Respiratory Failure
Early Non-invasive Ventilation Outside the Intensive Care Unit
A large multicentre, randomized, controlled trial to demonstrate that non invasive ventilation given at an early stage of acute respiratory failure (ARF) outside the intensive care unit (ICU) can prevent the deterioration of ARF…
- Trial name
- NAVIGATE (NCT01572337)
- Testing
- Non-invasive ventilation, Standard care
- Where
- 14 sites in Greece, Italy and 1 more
- Volunteers
- 520 people
- Sponsor
- Università Vita-Salute San Raffaele
Neuro-intensive Care Unit Patients, Brain Injuries
Third Ventricle Echographic Study for Neuro-intensive Care Unit Patients
Transcranial Doppler ultrasonography is usually used in the evaluation and management of patients with brain injury. This noninvasive method measures local blood flow velocity and direction in the proximal portions of large…
- Trial name
- ECHO-V3 (NCT02830269)
- Testing
- Transcranial Doppler ultrasonography measurements
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Montpellier
Respiratory Syncytial Virus Infections, Infections, Epidemics
Respiratory Syncytial Virus Infection in Neonatal Intensive Care Units Throughout Turkey: Prospective Multicenter Study (TurkNICU-RSV Trial)
The principle purpose of this multicenter trial is to determine the definition, timing and the percentage of nosocomial RSV epidemics throughout Turkey.
- Trial name
- TurkNICU-RSV (NCT01915394)
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people
- Sponsor
- Ankara University
Sepsis - to Reduce Mortality in the Intensive Care Unit, Sepsis
Beta-Lactam Antibiotics InitiaL ExpoSure OptimisEd in CriticallY Ill Patients with SEpsis
The aim of this study is to investigate if an initial short double dose of beta-lactam antibiotics will reduce mortality in critically ill patients with sepsis.
- Conditions
- Sepsis - to Reduce Mortality in the Intensive Care Unit, Sepsis, Septic Shock
- Trial name
- BULLSEYE (NCT06766461)
- Testing
- Double dosing of beta-lactam antibiotic
- Where
- Netherlands
- Volunteers
- 980 people
- Sponsor
- Erasmus Medical Center
Myasthenia Gravis, Guillain-Barre Syndrome
Ventilator Weaning Practices in Patients Intubated for Guillain-Barré Syndrome or Myasthenia Gravis
Guillain-Barré syndrome and myasthenia gravis are two neuromuscular diseases that are commonly managed in ICUs that may require different weaning protocols.
- Trial name
- GUIMAUVE (NCT07022028)
- Where
- France
- Volunteers
- 800 people
- Sponsor
- Poitiers University Hospital