Clinical trials: Intensive Care Unit Days
Neonatal Respiratory Distress, Preterm Birth
Study of the Feasibility of Early Lung Ultrasound in Neonatal Respiratory Distress in Premature Newborns Born Between 32 Weeks of Amenorrhea and 36 Weeks Plus 6 Days of Amenorrhea, Hospitalized in the Neonatal Pediatrics and Intensive Care Units of the Dijon University Hospital
Monocentric study carried out in the Neonatal and Intensive Care Units of the Dijon University Hospital. The objective is to evaluate the feasibility of performing a pulmonary ultrasound within 6 hours after admission in…
- Trial name
- REchoPP (NCT05737095)
- Testing
- Pulmonary ultrasound
- Where
- France
- Volunteers
- 69 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
ICU Acquired Weakness
Impact of Early Mobilization on Mechanical Ventilation Duration in Intubated Critically Ill Patients
The purpose of the present study is to compare usual care in terms of mobilization performed to intubated ICU patients to a standardized program designed to deliver early mobilization at least 5 days a week.
- Trial name
- EarlyMob (NCT02520193)
- Testing
- Protocolized early mobilization in ICU
- Where
- 23 sites in Belgium, France and 1 more
- Volunteers
- 772 people
- Sponsor
- University Hospital, Angers
AKI
Preadmission Metformin Exposure and Incidence of Acute Kidney Injury
More than 50% of ICU patients suffer from Acute kidney injury (AKI). Metformin shows protective properties in kidney disease. Our study aimed to validate AKI incidence among diabetes patients in the ICU with or without…
- Trial name
- NCT04631289
- Where
- China
- Volunteers
- 3,841 people
- Sponsor
- Second Affiliated Hospital of Guangzhou Medical University
Hypomagnesemia
Dynamic Magnesium Replacement Strategies and 28-Day Mortality in Non-Cardiac Critically Ill Patients With Hypomagnesemia: A Target Trial Emulation
This study looks at how different ways of giving magnesium (a nutrient) affect the risk of death within 28 days for adults with low magnesium levels who are in the intensive care unit (ICU) for non-heart-related reasons.
- Trial name
- NCT07380542
- Where
- China
- Volunteers
- 12,887 people
- Sponsor
- Fujian Provincial Hospital
Respiratory Syncytial Virus Infections, Immunocompromised Host
RSV, Influenza, and SARS-CoV-2 Outcomes in Severely Immunosuppressed Adults
Respiratory syncytial virus (RSV), influenza, and SARS-CoV-2 are common respiratory viruses. In healthy adults they usually cause mild, cold-like illness, but in people whose immune system is severely weakened - such as people…
- Conditions
- Respiratory Syncytial Virus Infections, Immunocompromised Host, Influenza, COVID - 19
- Trial name
- NCT07816471
- Volunteers
- 350 people
- Sponsor
- Hospital Italiano de Buenos Aires
Anesthesia
Anesthesia and Lymphocytes Apoptosis
Most researches revealed that volatile anesthetic sevoflurane has a more marked cardioprotective effect against ischemia compared with intravenous agent propofol.However, propofol has been suggested to be more benefit for…
- Trial name
- OPCAB (NCT01461551)
- Testing
- Sevoflurane, Propofol, combine of sevoflurane and propofol
- Where
- China
- Volunteers
- 105 people
- Sponsor
- Ruijin Hospital
Severe Acute Respiratory Failure
Intensive Care - GLObal Study on Severe Acute Respiratory Infection
IC-GLOSSARI (The Intensive Care GLObal Study on Severe Acute Respiratory Infection) is a multicentre, prospective, observational,14-day inception cohort study designed and conducted by the ESICM Trials Group to investigate the…
- Trial name
- NCT01936207
- Where
- Belgium
- Volunteers
- 800 people
- Sponsor
- European Society of Intensive Care Medicine
Acute Respiratory Distress Syndrome, Severe Community-Acquired Pneum
Nogapendekin Alfa-Inbakicept and iNKT Cells for Critically Ill Adults With Severe Community-Acquired Pneumonia (With or Without Sepsis/ARDS)
This Phase 2 study tests whether adding two immune therapies - nogapendekin alfa-inbakicept (NAI) and off-the-shelf iNKT cell infusions - to standard care can safely help critically ill adults with severe community-acquired…
- Conditions
- Acute Respiratory Distress Syndrome, Severe Community-Acquired Pneum, Sepsis, Lymphopenia / Immunoparalysis in Critically Ill Adults
- Trial name
- NCT07492888
- Testing
- Nogapendekin Alfa-Inbakicept (NAI), Allogeneic invariant Natural Killer T (iNKT) Cells (AgenT-797)
- Sponsor
- ImmunityBio, Inc.
Intertrochanteric Femur Fracture, Hip Fracture Surgeries
Inflammatory Indices, Early Mortality, and ICU Stay in Geriatric PFN Patients
This retrospective observational cohort study aims to evaluate the association between preoperative and postoperative inflammatory indices and early postoperative outcomes in geriatric patients undergoing proximal femoral nailing…
- Conditions
- Intertrochanteric Femur Fracture, Hip Fracture Surgeries, Geriatric Anesthesia
- Trial name
- PFN-RAR (NCT07607886)
- Where
- Turkey (Türkiye)
- Volunteers
- 233 people
- Sponsor
- Saglik Bilimleri Universitesi
Fluid and Electrolyte Imbalance, Anesthesia
BIA-Guided vs. Conventional Fluid Resuscitation in ICU Patients
In this study aimed to compare bioelectrical impedance analysis (BIA)-guided fluid resuscitation with conventional fluid management strategies in patients admitted to the intensive care unit (ICU) following major surgery.
- Trial name
- BIA-FLUID (NCT07142083)
- Testing
- Bioelectrical Impedance Analysis (BCM), Conventional Fluid Management
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ondokuz Mayıs University
Physician Fatigue
Impact of a Day Without Clinical Activity Before Night Shift on Non-technical Skills of Intensive Care Residents
In this proposal, investigators seek to address conclusively two knowledge gaps: 1) the lack of data on the impact of a schedule including a day off clinic before night shift on performances of residents in anesthesia or critical…
- Trial name
- REPOPREGARD (NCT05146856)
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Mortality Prediction
28-day Mortality Prediction for Critically Ill Patients in the Intensive Care Unit: Physician-nurse vs. Score
There are several scores for predicting mortality within 28 days in the intensive care unit, including APACHE 2, MPM 2 and MODS.
- Trial name
- NCT06665529
- Testing
- 28-day mortality prediction by ICU staff and mortality scores
- Where
- Israel
- Sponsor
- Meir Medical Center
Septic, Acute Respiratory Distress Syndrome
Lessening Organ Dysfunction With VITamin C in Septic ARDS
The primary objective of the study aims to compare the effect of high-dose intravenous vitamin C vs. placebo on a composite of death or persistent organ dysfunction - defined as continued dependency on mechanical ventilation, new…
- Trial name
- LOVIT ARDS (NCT04404387)
- Testing
- Administration of vitamin C
- Where
- France
- Volunteers
- 800 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Mortality
LODS Role in Predicting 30-day Mortality Outcome in ICU
LODS score for deceased ICU patients within 30 days is higher than survived ICU patients
- Trial name
- NCT03930160
- Testing
- Logistic Organ Dysfunction System Score
- Where
- Indonesia
- Volunteers
- 439 people
- Sponsor
- Universitas Indonesia
Total Parenteral Nutrition, Necrotizing Enterocolitis of Newborn
Probiotics/TPN in the NICU
The purpose of this study is to evaluate the effect of probiotic administration on TPN dependence in infants < 32 weeks GA and BW 1500 grams or less in the Banner - University Medical Center Phoenix and Banner Children's at…
- Trial name
- NCT04977817
- Testing
- Similac Probiotic Tri-Blend
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- Pediatrix
Pressure Injury
One-Day Prevalence Study on Pressure Injuries in Intensive Care Units
The objective of this study is to provide an up-to-date, global picture of the extent and patterns of pressure injuries in ICUs. Point prevalence studies are only of value when performed on a vast scale.
- Trial name
- DecubICUs (NCT03270345)
- Where
- Belgium
- Volunteers
- 13,340 people
- Sponsor
- European Society of Intensive Care Medicine
Intensive Care Unit Days
Proactive Ethics Intervention to Improve Intensive Care Unit (ICU) Care
The primary aim of the study is to demonstrate the value of a preemptive approach to ethics consultation in an ICU. The investigators hope to answer the question: Will proactive ethics interventions by a skilled and experienced…
- Trial name
- PEI (NCT00996814)
- Testing
- Proactive Ethics Intervention
- Where
- United States
- Volunteers
- 386 people
- Sponsor
- California Pacific Medical Center Research Institute
Hyperglycemia, Critical Illness
Normoglycaemia in Intensive Care Evaluation and Survival Using Glucose Algorithm Regulation (NICE - SUGAR STUDY)
The primary aim of the study is to compare the effects of the two blood glucose targets on 90 day all-cause mortality in Intensive Care patients who are predicted on admission to stay in the ICU for at least one full calendar…
- Trial name
- NCT00220987
- Testing
- Intensive Insulin Therapy, Conventional Insulin therapy
- Where
- Australia
- Volunteers
- 6,104 people
- Sponsor
- The George Institute
Intensive Care Patients, Relatives
Family Involvement in ICU
The aim of this prospective cohort study was to investigate the effect of the time spent with relatives of patients treated in a tertiary intensive care unit on patient outcomes.
- Conditions
- Intensive Care Patients, Relatives, Delirium in the Intensive Care Unit, Sedatives
- Trial name
- NCT06770751
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people
- Sponsor
- Istanbul University - Cerrahpasa
Respiratory Failure
Effect of Inspiratory Muscle Training on Duration of Mechanical Ventilation Support
A growing body of knowledge has documented that the diaphragm, the primary muscle of breathing, atrophies and weakens within days of instituting mechanical ventilation support.
- Trial name
- NCT01108575
- Testing
- IMST
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- University of Florida