Clinical trials: Intensive Care Unit Stay, open to volunteers
Pulmonary Embolism
The RAPID - PE Study: RESCUE Advanced Protocol for the Treatment of Pulmonary Embolism
To demonstrate the efficacy and safety of the 8F BASHIR™ .035 Endovascular Catheter and the 8F BASHIR™ S-B .035 Endovascular Catheter for the administration of pharmaco-mechanical catheter directed therapy using pulse sprays of…
- Trial name
- NCT06433011
- Testing
- The Bashir™ Endovascular Catheter, r-tPA
- Where
- 23 sites in United States
- Volunteers
- 500 people
- Sponsor
- Thrombolex, Inc.
Intensive Care Unit Syndrome, Critical Illness
Effectiveness of Stress Management Training in Reducing Caregiver Burden and Perceived Stress in ICU Families
This research helps to close an important gap in the provision of care to ICU families and introduces a structured and accessible psychological intervention to family caregivers of long-stay ICU patients.
- Trial name
- NCT07812376
- Testing
- Stress Management Training Program
- Volunteers
- 50 people
- Sponsor
- Al-Balqa Applied University
Length of Stay
Alberta Collaborative QI Strategies to Improve Outcomes of Moderate and Late Preterm Infants (ABC-QI Trial)
The ABC-QI Trial aims to implement collaborative quality improvement (QI) strategies to standardize care for 32-36 week infants in Level 2 and 3 Neonatal intensive care units (NICUs) across the province of Alberta.
- Trial name
- ABC-QI (NCT05231200)
- Testing
- QI Team Building, QI education, Standardized care bundle- respiratory care
- Where
- 12 sites in Canada
- Volunteers
- 9,500 people
- Sponsor
- University of Calgary
Delirium, Anxiety and Depression
Effects of Artificial Intelligence Nurse Orientation Program on Psychological Outcomes and Length of Hospital Stay in Intensive Care Unit
Artificial intelligence (AI), now an integral part of healthcare services and presents numerous opportunities. Customized treatment plans, clinical decision support systems, predictive analysis for disease prevention, patient…
- Conditions
- Delirium, Anxiety and Depression, Intensive Care Units (ICUs), Artificial Intelligence (AI)
- Trial name
- AINURSE-OP (NCT07171944)
- Testing
- Structured orientation program, Human Nurse
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people
- Sponsor
- Koç University
Hypoxic Respiratory Failure
Effect of FAST HUGS WITH ICU Approach on Length of Intensive Care Unit Stay in Patients With Hypoxic Respiratory Failure
This study will investigate the effect of the FAST HUGS WITH ICU approach on the length of stay in the intensive care unit in patients with hypoxic respiratory failure.
- Trial name
- NCT06901050
- Testing
- FAST HUGS WITH ICU approach
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Muş Alparslan University
Postpartum Depression (PPD), Self-Efficacy
NICU Utilization of Remote Voice Technology to Improve mateRnal Experience (NURTURE)
The study's objective is to conduct a Phase II randomized controlled trial examining the preliminary efficacy of the VoiceLove app compared to usual care on maternal postpartum depression in mothers with infants admitted to the…
- Conditions
- Postpartum Depression (PPD), Self-Efficacy, Parental Anxiety, Engagement, Patient
- Trial name
- NURTURE (NCT07214597)
- Testing
- VoiceLove mobile phone application
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Stress Disorders, Post-Traumatic
Parental EMDR Therapy After a Baby's Stay in the NICU
This randomized clinical trial evaluates the effectiveness of eye movement desensitization and reprocessing (EMDR) therapy in reducing symptoms of post-traumatic stress disorder (PTSD).
- Trial name
- EMDR-NICU (NCT07471321)
- Testing
- Eye Movement Desensitization and Reprocessing (EMDR), treatment as usual (TAU) (Control Group)
- Where
- Finland
- Volunteers
- 80 people
- Sponsor
- Kuopio University Hospital
AKI - Acute Kidney Injury, Critical Illness
Continuous Renal Replacement Therapy, Impact on Intensive Care Unit Length of Stay
This large national cohort study, including over 500,000 patients, where around 5% are treated with continuous renal replacement therapy (CRRT) , aims to evaluate the association between time to initiation of CRRT and intensive…
- Trial name
- CIILOS (NCT07586059)
- Testing
- continuous renal replacement therapy
- Volunteers
- 500,000 people
- Sponsor
- Karolinska Institutet
Frailty, Delirium Confusional State
Patients With Long-stay at ICU: Factors and Evaluation - Feasibility Study
Every year, many critically ill patients are admitted to an intensive care unit (ICU). Most stay only a few days, but a smaller group stays much longer.
- Conditions
- Frailty, Delirium Confusional State, Persistent Critical Illness, Post-Intensive Care Syndrome
- Trial name
- LIFE-ICU (NCT07851974)
- Where
- 4 sites in Sweden
- Volunteers
- 300 people
- Sponsor
- Uppsala University
Neonatal Hypoglycemia, Metabolic Complication
Pasteurised Donor Human Milk Supplementation for Term Babies
PRESENT is a multi-center randomised controlled trial that aims to assess whether access to pasteurized donor human milk as supplementary nutrition in the first five days of life for term infants born to women with diabetes in…
- Conditions
- Neonatal Hypoglycemia, Metabolic Complication, Cows Milk Allergy, Hospital Length of Stay
- Trial name
- PRESENT (NCT06993103)
- Testing
- Standard care Cow's milk based formula, Dietary Supplement: PDHM Pasteurised Donor Human Milk
- Where
- 4 sites in Australia
- Volunteers
- 1,444 people
- Sponsor
- The University of Queensland
Sepsis, Sepsis and Coagulopathy
Sepsis-associated Thrombocytopenia and Platelet Transfusion （STAPT）
Currently, there are no multicenter studies on platelet transfusion for SAT patients, and the benefits and risks of platelet transfusion still require further validation based on large-sample data.
- Trial name
- NCT07230067
- Testing
- SAT patients
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Intensive Care Unit, SARS-Cov-2
COVID-19 - Study of the Kinetics of the Immune Response During the Intensive Care Unit Stay in Adult Patients Infected With SARS-CoV-2: Multicentric Non Interventional Study
Infection with the SARS-CoV-2 coronavirus (COVID-19) has recently been identified as a pandemic due to the speed and global scale of its transmission.
- Trial name
- RICO (NCT04392401)
- Testing
- Collection of blood samples in order to create a biocollection
- Where
- 8 sites in France
- Volunteers
- 200 people
- Sponsor
- Hospices Civils de Lyon
Critical Illness, Family Satisfaction
Patient Characterization Panel to Improve Satisfaction With the Intensive Care Unit Stay (CONNECT)
Intensive care units (ICUs) present unique challenges to humanized, person-centered care. The severity of illness and the demands of complex technical management can displace attention from patients as individuals, making it…
- Conditions
- Critical Illness, Family Satisfaction, Critical Care, Intensive Care
- Trial name
- CONNECT (NCT07830043)
- Testing
- Patient-as-a-Person Characterization Panel with Staff Training, Standard ICU Care
- Where
- 2 sites in Brazil
- Volunteers
- 966 people
- Sponsor
- University of Sao Paulo General Hospital
Post Intensive Care Syndrome
Post-Resuscitation Interdisciplinary Consultation System: a Randomized, Multicenter, Interventional Study to Assess Quality of Life After a Stay in the COPRéa Intensive Care Unit
A patient's stay in the ICU is not without consequences and can cause various physical and/or psychological sequelae such as anxiety, depression, post-traumatic stress disorder (PTSD), physical weakness and memory problems.
- Trial name
- COPRéa (NCT05625867)
- Testing
- Psychological and quality of life questionnaires, Interdisciplinary consultation at 4/5 months
- Where
- France
- Volunteers
- 404 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Intensive Care Patients, Relatives
Family Involvement in ICU
The aim of this prospective cohort study was to investigate the effect of the time spent with relatives of patients treated in a tertiary intensive care unit on patient outcomes.
- Conditions
- Intensive Care Patients, Relatives, Delirium in the Intensive Care Unit, Sedatives
- Trial name
- NCT06770751
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people
- Sponsor
- Istanbul University - Cerrahpasa
Early Mobilization, Postoperative Care
Early Mobilization and Prolonged ICU Stay in Postoperative Patients
This prospective observational cohort study aims to evaluate early mobilization in adult postoperative patients admitted to the intensive care unit (ICU) and to investigate its association with short-term clinical outcomes.
- Trial name
- NCT07765017
- Volunteers
- 80 people
- Sponsor
- Ankara Training and Research Hospital
Acute Kidney Injury
Frailty and Outcomes in Critically Ill Patients Receiving CRRT
This nationwide observational cohort study will investigate the association between frailty, chronological age, and clinical outcomes in critically ill patients receiving continuous renal replacement therapy (CRRT) in Sweden.
- Trial name
- CRRT-AF (NCT07837219)
- Volunteers
- 22,000 people
- Sponsor
- Karolinska Institutet
ICU Stay, Muscle Atrophy
Weaning Assessment by Peripheral Muscle Ultrasonography
In this study, which aims to investigate the relationship between the weaning process and respiratory muscles-assessed via ultrasonographic measurement of peripheral muscle thickness-in patients over the age of 18 who have been…
- Conditions
- ICU Stay, Muscle Atrophy, Ultrasonography, Weaning Mechanical Ventilation
- Trial name
- NCT07860879
- Testing
- Ultrasonography of peripheral muscle (rectus femoris or vastus intermedius), Ultrasonography of diaphragma
- Volunteers
- 100 people
- Sponsor
- Taksim Egitim ve Arastirma Hastanesi
Cost Analysis, Length of ICU Stay
An Artificial Intelligence Model for Intensive Care Length of Stay, Neurological Outcome and Costs Estimation After Cardiopulmonary Resuscitation: a Cohort Study.
The study aims to overview patients registered to Bezmialem Vakıf University Hospital Intensive Care Unit after successive cardiac arrest resuscitation from October 2010 to September 2025.
- Conditions
- Cost Analysis, Length of ICU Stay, Neurological Outcome
- Trial name
- NCT07210866
- Testing
- no physical or medical interventions
- Volunteers
- 5,000 people
- Sponsor
- Bezmialem Vakif University
Ventilator-Associated Pneumonia (VAP), Central Line-Associated Bloodstream Infection
Impact of Nurses' Behavior Change and Evidence-Based Practice Implementation on Quality Indicators in Intensive Care Units in Low- and Middle-Income Countries
Study title: Impact of nurses' behavior change and implementing evidence-based practice to improve quality indicators in intensive care units in low-and middle-income countries Background and Rationale: Quality care is crucial…
- Conditions
- Ventilator-Associated Pneumonia (VAP), Central Line-Associated Bloodstream Infection, Pressure Ulcers (Hospital-acquired Pressure Injuries), Prolonged Intensive Care Unit Length of Stay
- Trial name
- NCT07397364
- Testing
- Evidence based practices bundles of care
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University