Clinical trials: Intensive Care Units
Respiratory Failure, Mechanical Ventilation Complication
Effect of Sedation Strategy on Duration Mechanical Ventilation in Patient After Cardiac Surgery
There is a direct relationship between the sedative agent and the duration of ventilation.
- Conditions
- Respiratory Failure, Mechanical Ventilation Complication, Sedation Complication
- Trial name
- NCT05451121
- Testing
- Propofol, Dexmedetomidine, Propofol and dexmedetomidine
- Where
- Ukraine
- Volunteers
- 356 people
- Sponsor
- Anesthesia Research Group UA
To Evaluate the Effect of Online Education on Nurses' Self-efficacy Regarding Blood Transfusion
Self-Efficacy Levels of Nurses on Safe Blood and Blood Product Transfusion
A quasi-experimental study was conducted in a pre-test-post-test design to investigate the self-efficacy levels of nurses working in a cardiovascular surgery Intensive Care Unit regarding safe blood and blood product transfusion…
- Trial name
- NCT06542185
- Testing
- online education
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Yuksek Ihtisas University
Segmental Lung Atelectasis
Segmental Lung Recruitment: a Randomized Controlled Trial
This study compares two ways of reopening collapsed parts of the lung in patients on a ventilator. In one group, doctors use a small camera (bronchoscope) to guide air pressure directly to the blocked part of the lung.
- Trial name
- NCT07442708
- Testing
- Segmental lung recruitment, Conventional lung recruitment
- Volunteers
- 20 people
- Sponsor
- Clinical Hospital Center Rijeka
Tetanus
Real-time Artificial Intelligent (AI)-Assisted Muscle Ultrasound for Monitoring Muscle Mass Reduction in ICU Patients
This study aims to investigate the feasibility of using a real-time artificial intelligent (AI)-assisted tool for Rectus Femoris cross sectional area measurement from muscle ultrasound to improve reliability, reduce inter- and…
- Trial name
- RAIMUS (NCT06034093)
- Testing
- Real-time AI-assisted muscle ultrasound
- Where
- Vietnam
- Volunteers
- 254 people
- Sponsor
- Oxford University Clinical Research Unit, Vietnam
Heart Failure
Comparison of CorWatch With Right Heart Catheter Measurements in Heart Failure
This is an observational study to evaluate the agreement between the InCardia diagnostic technology CorWatch for the assessment of venous pressure in human subjects.
- Trial name
- NCT04928326
- Testing
- CorWatch
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- InCardia Inc.
Ventilator-Associated Pneumonia
Ventilator-Associated Pneumonia (VAP) in Intensive Care Unit (ICU)
Ventilator-associated pneumonia (VAP) is very common in the intensive care unit (ICU), affecting 9 to 40% of ICU patients and mortality rates range from 20 to 50% and may reach more than 70% when the infection is caused by…
- Trial name
- NCT00935285
- Where
- Greece
- Volunteers
- 300 people
- Sponsor
- University of Thessaly
Critical Illness, Muscle Wasting
Acute Skeletal Muscle Wasting and Relation to Physical Function in Patients Requiring ECMO
The purpose of this study is to describe the changes in quadriceps muscle size and quality over the first 10 days on extracorporeal membrane oxygenation (ECMO) using ultrasound imaging.
- Conditions
- Critical Illness, Muscle Wasting, Extracorporeal Membrane Oxygenation
- Trial name
- NCT03026985
- Testing
- Observational cohort
- Where
- Australia
- Volunteers
- 25 people
- Sponsor
- The Alfred
Anxiety, Mood Disorders
Assisted Animal Therapy: ReAnimal
Assisted animal therapy (AAT) is getting more and more used worldwide, in such areas as gerontology, psychiatry, or oncology. It is a complementary therapy, and benefits for patients are various, including decrease of anxiety.
- Conditions
- Anxiety, Mood Disorders, Post Traumatic Stress Disorder
- Trial name
- ReAnimal (NCT03898843)
- Testing
- Animal assisted therapy, Nasal swab sampling, STAI-Y and POMS Questionnaires
- Where
- France
- Volunteers
- 7 people
- Sponsor
- Hospices Civils de Lyon
Premature Infant Disease
A Randomized Controlled Trial to Evaluate the Effect of White Noises and Parental Voices As Protectors Against Noise Damage in a Neonatal Intensive Care Unit
The goal of this Randomized Controlled Trial is to test the efficacy of listening to white noises and parental voices against environmental noise damage in premature babies admitted to the Newborn Intensive Care Unit.
- Trial name
- NCT06150404
- Testing
- White Noises and Maternal and/or Paternal voices
- Where
- Italy
- Volunteers
- 11 people
- Sponsor
- Istituto Giannina Gaslini
Intensive Care Unit Syndrome, Critical Illness
Effectiveness of Stress Management Training in Reducing Caregiver Burden and Perceived Stress in ICU Families
This research helps to close an important gap in the provision of care to ICU families and introduces a structured and accessible psychological intervention to family caregivers of long-stay ICU patients.
- Trial name
- NCT07812376
- Testing
- Stress Management Training Program
- Volunteers
- 50 people
- Sponsor
- Al-Balqa Applied University
Pneumonia
Errors in Prescription Antibiotics in Ventilator-associated Pneumonia
The infection is a major risk to hospitalized patients, especially those admitted to the Intensive Care Unit (ICU) and an unfavorable factor in the outcome of critically ill patients, increasing costs and prolonging…
- Trial name
- NCT02074033
- Where
- Brazil
- Volunteers
- 130 people
- Sponsor
- Federal University of Uberlandia
Palliative Care
Palliative Care in the ICU
The study compares early palliative care consultation to standard of care in the medical intensive care unit (ICU). The study will assess if the intervention leads to an increased proportion of clearly delineated goals of care…
- Trial name
- NCT03263143
- Testing
- Palliative Care
- Where
- United States
- Volunteers
- 242 people
- Sponsor
- Washington University School of Medicine
Noise in the ICU, Sleep Quality in Adult ICU Patients
Noise in the Intensive Care Unit
Rationale: Sound levels in the Intensive Care Unit are frequently reported to exceed the recommended levels. It is plausible to assume that this causes sleep disturbance in the patients on the ICU.
- Trial name
- NCT01826799
- Where
- 6 sites in Netherlands
- Volunteers
- 75 people
- Sponsor
- Jeroen Bosch Ziekenhuis
Hypotension
Assessment of Automatic Relays by Intensive Basis Advantage Compared With Manual Relays, on the Hypotension Risks, During Noradrenalin Administration
Circulatory failures are the main cause of admissions in the intensive care unit. It is recommended to prescribe to these patients an intravenous injection of catecholamine to correct this dysfunction and to keep an hemodynamic…
- Trial name
- ARIBA (NCT01127152)
- Testing
- Measure of arterial pressure
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Departemental Vendee
Hemophagocytic Lymphohistiocytosis
Comparison of Two Etoposide Initiation Strategies for Severe Hemophagocytic Lymphohistiocytosis
Hemophagocytic lymphohistiocytosis (HLH) is an immune-mediated disorder characterized by hyperactivation of the immune system, leading to a cytokine storm responsible for organ failures.
- Trial name
- TIC-TAC-SAM (NCT07497438)
- Testing
- Etoposide (Early strategy), Etoposide (Delayed strategy)
- Where
- France
- Volunteers
- 176 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Critical Illness, ARDS
Replacing Protein Via Enteral Nutrition in a Stepwise Approach in Critically Ill Patients
In this study, we will explore the feasibility of a randomized controlled trial that will compare high protein dose from ICU day 6 to 14 with moderate protein intake.
- Conditions
- Critical Illness, ARDS, Septic Shock, Multiple Trauma
- Trial name
- Replenish (NCT03480555)
- Testing
- Replenish Protein, Standard protein
- Where
- 2 sites in Saudi Arabia
- Volunteers
- 40 people
- Sponsor
- King Abdullah International Medical Research Center
Long-term Sedation for Mechanical Ventilation, Critically Ill Intensive Care Unit Patients
Remimazolam vs Propofol for Long-Term Sedation in Mechanically Ventilated ICU Patients
This multicenter, randomized, controlled, non-inferiority trial is designed to determine whether remimazolam is non-inferior to propofol for prolonged sedation in adult ICU patients requiring mechanical ventilation for ≥48 hours.
- Trial name
- RePro-ICU (NCT07880548)
- Testing
- Remimazolam group, Propofol group
- Where
- 21 sites in China
- Volunteers
- 274 people
- Sponsor
- Sun Yat-sen University
Delirium
Effect of Auditory Stimulation by Family Voices in Preventing Delirium: A Randomized Controlled Trial
Delirium is an acute cerebral dysfunction syndrome characterized by acute fluctuating changes in consciousness, cognitive dysfunction, and disorientation.
- Trial name
- NCT05732584
- Testing
- structured family voice stimulation, unstructured family voice stimulation
- Where
- China
- Volunteers
- 213 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Physiological Parameters
Monitoring of Patient Physiological Parameters in Real Life Using OXYFLEX® Biosensors Versus Standard Monitoring
The purpose of this study is to use the OXYFLEX® device in real care conditions during the hospital management of a population of patients from various hospital services.
- Trial name
- OXYVIVO (NCT07037784)
- Testing
- Continuous monitoring of vital constants with OXYFLEX® biosensor.
- Where
- France
- Volunteers
- 102 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Urinary; Sepsis
PSP as Indicator for Urinary Sepsis in ICU
Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. For clinical operationalization, organ dysfunction can be represented by an increase in the Sequential Organ Failure Assessment…
- Trial name
- NCT06090526
- Testing
- pancreatic stone protein "PSP" measurement
- Volunteers
- 80 people
- Sponsor
- Ain Shams University