Clinical trials: Intentional Self Harm
Self-Harm, Depression
Signatures of N-Ac for Non-Suicidal Self-Injury in Adolescents
To measure NAC-induced changes to concentrations of glutathione (GSH) in the anterior cingulate cortex (ACC) as measured by magnetic resonance spectroscopy (MRS) in 36 adolescents and young adults with NSSI (12 in each group…
- Conditions
- Self-Harm, Depression, Suicide
- Trial name
- NCT04005053
- Testing
- N-acetyl cysteine
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Minnesota
Suicide, Attempted, Suicide
The Catalonia Suicide Risk Code Epidemiology Study: an Epidemiological Study of Suicide Attempts in Catalonia, Spain
Suicide attempts (SA) constitute a major public health issue worldwide. Research suggests that 2.7% of adult people ever attempt suicide; among children and adolescents this is estimated to be 6.0%.
- Conditions
- Suicide, Attempted, Suicide, Suicide and Self-harm
- Trial name
- CSRC-Epi (NCT04235127)
- Testing
- sociodemographic variables, somatic conditions, mental disorders, treatment and drug use
- Volunteers
- 186,000 people
- Sponsor
- Hospital del Mar Research Institute (IMIM)
Depression and Self-Harm
RCT of the Clinical and Cost Effectiveness of Cognitive Behaviour Therapy (CBT) Delivered Remotely Versus Treatment as Usual in Adolescents and Young Adults With Depression Who Repeatedly Self-harm
A randomized controlled trial to test the whether remote delivery of cognitive based therapy (CBT) is clinically and cost effective when compared to treatment as usual in adolescents and young adults with depression who self-harm.
- Trial name
- eDASH (NCT02377011)
- Testing
- Problem solving cognitive behaviour therapy (PS CBT)
- Where
- 4 sites in United Kingdom
- Volunteers
- 22 people
- Sponsor
- University of Nottingham
Vitiligo, Depressive Episode
Mental Health Associations With Vitiligo
This cohort study is a large population-based study in the UK to determine the risks of comorbid mental health conditions (including depression, anxiety and other potential psychological complications of vitiligo) in adults with…
- Conditions
- Vitiligo, Depressive Episode, Recurrent Depressive Disorder, Anxiety Disorders
- Trial name
- NCT04953338
- Testing
- Exposure of mental health condtion of interest
- Where
- United Kingdom
- Volunteers
- 36,104 people, healthy volunteers welcome
- Sponsor
- Momentum Data
Self Harm
PsiloIMAGINE: A Psychedelic-augmented Mental Imagery-based Intervention for Young People With Self-harm
Approximately 20% of young people experience self-harm behaviour in their lives. Self-harm can occur across different mental health disorders, and lead to negative outcomes and risk of suicide.
- Trial name
- PsiloIMAGINE (NCT06798636)
- Testing
- Psilocybin 5 mg with cognitive behavioural therapy intervention
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Imperial College London
Suicidal Ideation, Self-Injurious Behavior
Youth Suicide and Self-Harm Intervention: Clinical and Biological Outcomes Study
The goal of this clinical trial is to develop and evaluate youth-focused intervention programs for suicide and self-harm that are tailored to the psychological, developmental, and cultural characteristics of Korean adolescents…
- Conditions
- Suicidal Ideation, Self-Injurious Behavior, Suicide, Attempted
- Trial name
- SHIELD (NCT07395752)
- Testing
- Self-Harm Intervention and Education for Long-term Development (SHIELD) Program, General Mental Health Education
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Ajou University School of Medicine
Suicide and Self Harm
Implementing a Brief Suicide Intervention for High Risk Youth With Front-Line Juvenile Justice Staff
A youth's contact with the juvenile justice system represents an opportune moment for suicide screening and brief suicide intervention for indicated youth.
- Trial name
- NCT02981420
- Testing
- Safety planning
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Suicidal Ideation, Suicide Attempt
Efficacy, Effectiveness, and Implementation of Jaspr Health in Emergency Department- Part B
This Study will evaluate the implementation of a multi-component suicide prevention technology (Jaspr Health) that facilitates delivery of suicided-related evidence-based practices (EBPs) while replacing wasted waiting time with…
- Conditions
- Suicidal Ideation, Suicide Attempt, Self Harm
- Trial name
- Jaspr-PartB (NCT06311591)
- Testing
- Jaspr App
- Where
- 4 sites in United States
- Volunteers
- 27,908 people
- Sponsor
- University of Massachusetts, Worcester
Psychological Orientation, Acceptance Processes
Commitment and Motivation in a Brief DBT Intervention for Self Harm
Research suggests that individuals with Borderline Personality Disorder (BPD) experience low motivation for change (Skodal, Buckley, \& Charles, 1983).
- Trial name
- NCT02354183
- Testing
- DBT Skills Training
- Where
- Canada
- Volunteers
- 39 people
- Sponsor
- Centre for Addiction and Mental Health
Self Harm, Suicidal Ideation
Leverage Noninvasive Transcutaneous Vagus Nerve Stimulation to Reduce Suicidal Behaviors in Vulnerable Adolescents
Suicidal thoughts, suicide attempts, and suicide are increasingly common in adolescence. Current face-to-face prevention approaches are of limited effectiveness, rely on extensive resources, and are at odds with adolescents'…
- Trial name
- NCT05602779
- Testing
- tVNS Program, Phone App Program, tVNS and Phone App Program
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- University of Notre Dame
Intentional Self Harm
Long Term Efficacy of DBT-A in Adolescents With Repetitive Self-harming and Suicidal Behaviours
The purpose of the study is to evaluate the long-term efficacy of dialectical behavior therapy (DBT) in treatment of adolescents with deliberate self harm compared to enhanced usual care (EUC).
- Trial name
- NCT01593202
- Testing
- Dialectical behavior therapy, Enhanced usual care
- Where
- Norway
- Volunteers
- 77 people
- Sponsor
- Oslo University Hospital
Self-Harm, Deliberate, Suicidal Ideation
Testing the Competency-based Theory of Change for Suicide Risk Among Young Male Internet Users With Societal Masculinity
To propose a competency-based theory of change for reducing suicide risks among male Internet users with salient traits of societal masculinity; To test whether the theory of change using the competency-based model has additional…
- Conditions
- Self-Harm, Deliberate, Suicidal Ideation, Masculinity
- Trial name
- NCT04591223
- Testing
- Competency-based physical training (CbM)
- Where
- Hong Kong
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Suicidal Ideation, Suicide and Self-harm
BRAVA: Building Resilience and Attachment in Vulnerable Adolescents
The prevalence of suicidal ideation (SI) among adolescents in North America is high, making it critical to develop evidence-based brief interventions for adolescents with SI that target healthy coping skills and relationships.
- Trial name
- BRAVA (NCT04751968)
- Testing
- Group Intervention, Enhanced Treatment as Usual
- Where
- Canada
- Volunteers
- 99 people
- Sponsor
- Children's Hospital of Eastern Ontario
Suicide, Suicide Prevention
Comparing Suicide Prevention Interventions to Guide Follow-up Care: The SPRING Trial
Pragmatic randomized controlled trial to compare the effectiveness of two-way Caring Contacts text messages vs. one-way Caring Contacts text messages vs. enhanced usual care for suicide prevention in adults and adolescents.
- Conditions
- Suicide, Suicide Prevention, Suicide and Self-harm
- Trial name
- SPRING (NCT06128239)
- Testing
- Caring Contacts
- Where
- United States
- Volunteers
- 854 people
- Sponsor
- St. Luke's Health System, Boise, Idaho
Suicidal Ideation, Suicidal and Self-injurious Behavior
Harry Potter as a Novel Educational Paradigm to Improve Mental Wellness in Children: A Prospective Trial
School-based mental health literacy interventions have been shown to reduce and/or prevent suicidal ideation and attempts. Most programs to date include an adapted version of Cognitive Behavioural Therapy (CBT) - the gold…
- Conditions
- Suicidal Ideation, Suicidal and Self-injurious Behavior, Suicide Attempt
- Trial name
- NCT04770168
- Testing
- Cognitive Behavioral Therapy Curriculum
- Where
- Canada
- Volunteers
- 3,204 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Suicide, Mental Disorder
Systems Aligning for Equity (SAFE) Spaces
The goal of this 2-arm cluster randomized clinical trial is to test whether an evidence-based staff training and coaching model specifically designed as a response to legal system-involved youths' and frontline staff's mental…
- Conditions
- Suicide, Mental Disorder, Mental Health, Burnout, Professional
- Trial name
- SAFE Spaces (NCT05658068)
- Testing
- SAFE Spaces training and coaching
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- New York University
Substance Use, Deliberate Self-harm
Evaluation of a Brief Surf the Urge Intervention
The purpose of this study is to evaluate the effectiveness of a brief "Surf the Urge" intervention to reduce adolescent and young adult (i.e., 14 to 24 years old) urge-related behaviors.
- Conditions
- Substance Use, Deliberate Self-harm, Trichotillomania, Aggression
- Trial name
- SUBMI (NCT02771886)
- Testing
- Surf the Urge
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Kimberly N Schubert
Eating Behavior, Self Harm
Reducing Suicide Risk Associated With Weight Loss
The purpose of this study is to examine the efficacy of an intervention aimed at promoting a healthy lifestyle and reducing risk factors associated with eating pathology, nonsuicidal self-injury, and suicidal behavior.
- Conditions
- Eating Behavior, Self Harm, Weight Loss
- Trial name
- NCT03541824
- Testing
- Body Acceptance Program
- Volunteers
- 59 people
- Sponsor
- Florida State University
Suicide, Suicidal Ideation
Intensive Crisis Intervention
The study's purpose is to improve the clinical management of severe crises experienced by youth with psychiatric disorders by examining a brief, evidence-based alternative to inpatient psychiatric care.
- Conditions
- Suicide, Suicidal Ideation, Suicide, Attempted, Suicide and Self-harm
- Trial name
- ICI (NCT06476886)
- Testing
- Intensive Crisis Intervention (ICI), Adolescent Psychiatric Inpatient Unit (APIU)
- Where
- United States
- Volunteers
- 213 people
- Sponsor
- Jennifer Hughes
Psychosis, Suicide Prevention
Cognitive AppRoaches to coMbatting Suicidality
This is a randomised controlled trial which investigates the effectiveness of CARMS (Cognitive AppRoaches to coMbatting Suicidality) therapy in reducing suicidal thoughts and how well CARMS works in practice within the NHS.
- Conditions
- Psychosis, Suicide Prevention, Suicidality
- Trial name
- CARMS (NCT03114917)
- Testing
- Cognitive AppRoaches to coMbatting Suicidality (CARMS)
- Where
- 4 sites in United Kingdom
- Volunteers
- 329 people
- Sponsor
- University of Manchester