Clinical trials: Interaction
Opioid-Related Disorders
Interactive Voice Response (IVR) for Methadone Patients
This study is designed to test whether a telephone call-in program is a feasible way to collect mood and drug-related information in individuals enrolled in a methadone maintenance program.
- Trial name
- NCT00237406
- Testing
- interactive voice response
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Butler Hospital
Healthy
Clinical Trial to Investigate the Pharmacokinetic/Pharmacodynamic Drug-Drug Interaction of Pyrimethamine and Metformin IR
This study aims to investigate the pharmacokinetic/pharmacodynamic drug-drug interaction of pyrimethamine and metformin IR after oral administration in healthy male volunteers.
- Trial name
- NCT01973933
- Testing
- Metformin and Pyrimethamine
- Where
- South Korea
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Premature Birth
A Longitudinal Study of Effectiveness of Early Intervention for Preterm Infants
The main purpose of this study is to extend the investigators' previous research to longitudinally examine the effectiveness of three early intervention programs: usual care program, clinic-based intervention program and…
- Trial name
- NCT00946244
- Where
- Taiwan
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Healthy Adults
A PK Study to Assess the Drug-drug Interaction of a BCRP Inhibitor on Adagrasib
A Phase 1, Open-label, One-sequence Crossover Study to Investigate the Effect of a Breast Cancer Resistance Protein Inhibitor on the Single-dose Pharmacokinetics of Adagrasib in Healthy Adult Subjects
- Trial name
- NCT05924152
- Testing
- Adagrasib, Eltrombopag + adagrasib
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Mirati Therapeutics Inc.
Distraction Methods, Nursing Care
Effects of Cartoons & Interactive Storytelling on Fear and Comfort in 6-9 Year Olds During Nebulizer Treatment
Fear and anxiety experienced by children during inhalation therapy (using a nebulizer or vaporizer) are key factors that make treatment compliance difficult and reduce the quality of care.
- Trial name
- NCT07516249
- Testing
- Cartoon Watching, Interactive storytelling synchronized with breath, Standard Group
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Mersin University
COPD
Pharmacokinetic Interaction Study of Glycopyrrolate and Formoterol in Healthy Volunteers
This study will be carried out in healthy volunteers with the primary objective to evaluate the pharmacokinetic interaction between Glyco and Formoterol administered using a pressurised metered dose inhaler (pMDI).
- Trial name
- TRIPLE 1 (NCT01398111)
- Testing
- Glycopyrrolate + Formoterol, Glycopyrrolate, Formoterol
- Where
- Belgium
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Chiesi Farmaceutici S.p.A.
Health Behavior
Family Health Promoter - an Online Interactive Platform for Parents to Promote Healthy Habits
The goal of this observational study is to test a working prototype of a web-based application, Family Health Promoter (FHP), designed to support parents/guardians in facilitating positive health behavior change within their…
- Trial name
- NCT07870304
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Bridget Biggs
Epilepsy
A Randomized Controlled Trial to Investigate Possible Drug-drug Interactions Between Clobazam and Cannabidiol
This trial consists of 2 parts: a double-blinded phase and an open-label extension phase. The blinded phase only will be described in this record.
- Trial name
- NCT02565108
- Testing
- GWP42003-P 20 mg/kg/Day Dose, Clobazam
- Where
- 6 sites in Spain, United Kingdom
- Volunteers
- 20 people
- Sponsor
- Jazz Pharmaceuticals
Education
M-learning to Improve Professional Competencies in Health Sciences
The aim of this study is to investigate whether a mobile application is useful for improving knowledge about professional competencies in students enrolled in Health Sciences degrees.
- Trial name
- NCT03335397
- Testing
- M-learning application, Traditional learning process
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Universidad de Granada
Hypoxia, Altitude, Exercise Tolerance
Direct and Cross Effects of Adaptation to Systemic Hyperthermia: Impact on Quality of Life, Neurohormonal and Psychophysiological Human Status
Life expectancy and quality of human life are important indicator of the sustainable development of the society. At the same time, the physical, functional, emotional and psychological components of the of the quality of life…
- Conditions
- Hypoxia, Altitude, Exercise Tolerance, Metabolic Disturbance, Quality of Life
- Trial name
- NCT04089410
- Testing
- Hyperthermic Fitness Treatment (HFT), Physical Examination, Assessment of Cardiorespiratory Fitness
- Where
- Russia
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Healhty
Drug-drug Interaction Study Between UIC202304, and UIC202305
A randomized, open-label, two-sequence, two-period, multiple-dose, study to evaluate pharmacokinetic drug-drug interaction, safety and tolerability of UIC202304 and UIC202305 in healthy volunteers.
- Trial name
- NCT07735052
- Testing
- UIC202304 and co-administration of UIC202304 and UIC202305, UIC202305 and co-administration of UIC202304 and UIC202305
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Korea United Pharm. Inc.
Chronic Kidney Diseases, Hypertension
Interactive Computer-adaptive Chronic Kidney Disease Education Program
The goal of this pilot clinical trial is to evaluate a culturally tailored computerized education program in hospitalized African-American patients with advanced chronic kidney disease (CKD).
- Trial name
- ICCKD (NCT06364358)
- Testing
- Computerized CKD Education, Usual Hospital Care
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Chicago
Hemodialysis, Nurse
Interactive vs. Standard Video Education for Improving Outcomes in Hemodialysis Patients
The goal of this clinical trial is to find out if educational videos-especially interactive ones-can help people on dialysis better manage their treatment.
- Conditions
- Hemodialysis, Nurse, Educational Videos, Patient Activation
- Trial name
- NCT07099326
- Testing
- Educational Method Using Interactive Video, Educational Method Using Conventional Video
- Volunteers
- 165 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Prostate Cancer, Endometriosis
A Phase 1 Study to Evaluate the Effects of Fluconazole and Atorvastatin on the Pharmacokinetics of TAK-385 in Healthy Subjects
This is a nonrandomized, open-label, fixed-sequence, 2-arm study designed to assess the effect of multiple doses of fluconazole or atorvastatin on the single-dose pharmacokinetics of TAK-385 in healthy adult subjects.
- Trial name
- NCT02093390
- Testing
- TAK-385, Fluconazole, Atorvastatin
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Millennium Pharmaceuticals, Inc.
Healthy Participants
Drug-drug Interaction Trial of AP31969 and Carbamazepine or Itraconazole
The primary objective of the trial is to assess the effect of multiple doses of the cytochrome P450 (CYP3A4) enzyme inducer carbamazepine (Part A) or the CYP3A4 inhibitor itraconazole (Part B) on the single-dose pharmacokinetics…
- Trial name
- NCT07449390
- Testing
- AP31969, Carbamazepine, Itraconazole
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Acesion Pharma
Hypertension, Diabetes
Developing Accessible Telehealth Programs for Diabetes and Hypertension Management in Bolivia
The purpose of the study is to evaluate the feasibility and impact of an automated phone system in monitoring and improving self-care and health outcomes among patients with diabetes and/or hypertension in Bolivia, in addition to…
- Trial name
- NCT02429297
- Testing
- HITCM-only, HITCM+CP
- Where
- Bolivia
- Volunteers
- 110 people
- Sponsor
- University of Michigan
Healthy Adults
A Study to Learn if the Study Medicine Called Fluconazole Changes How the Other Body Processes the Study Medicine PF-07248144
The purpose of the study is to learn how the study medicine called fluconazole changes how the body processes the other study medicine called PF-07248144.
- Trial name
- NCT07636018
- Testing
- PF-07248144, Fluconazole
- Where
- Belgium
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pfizer
Depression
Dyadic Interactions in Depressed and Non-Depressed Mothers and Their Infants
This study will examine 1) differences among mothers behaviors and how these behaviors influence their infants reactions, and 2) how mother-child interactions relate to children s temperament, and cognitive (thought processing)…
- Trial name
- NCT00044174
- Where
- United States
- Volunteers
- 701 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Drug Drug Interaction
Fruquintinib CYP3A Inhibitor and Inducer Study
A study to assess the effect of itraconazole, a strong CYP3A inhibitor, and the effect of rifampin, a strong CYP3A inducer, on the pharmacokinetics of fruquintinib in healthy subjects.
- Trial name
- NCT04557397
- Testing
- Fruquintinib, Itraconazole, Rifampin
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Hutchison Medipharma Limited
Hypertension, Menopause
Hemodynamic and Salivary Responses of 12 Weeks of Training With Different Anti-hypertensive
Different classes of antihypertensives may have different responses when associated with exercise. Thus, this study aims to compare the responses of the association of 12 weeks of aerobic exercise and weightlifting with different…
- Trial name
- NCT03529838
- Testing
- Combined exercise
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Federal University of Uberlandia
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