Clinical trials: Interaction
Schizophrenia Spectrum Disorders, Social Cognition
Using Illusions to Boost Social Cognition
This study aims to explore whether the observation of complex visual objects can help improve social cognition in people living with psychotic disorders.
- Trial name
- SOLLUSIONS (NCT07602712)
- Testing
- Visual-illusion social cognition session (immediate), Visual-illusion social cognition session (delayed)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Hôpital le Vinatier
Hepatitis C Virus
TMC435-TiDP16-C108 - A Study in Healthy Volunteers Investigating the Pharmacokinetic Interaction Between TMC435 and Digoxin and Between TMC435 and Rosuvastatin
The purpose of this study is to investigate the effect of steady-state concentrations of TMC435 on the single-dose pharmacokinetics of digoxin or rosuvastatin , and the effect of a single dose of digoxin or rosuvastatin on the…
- Trial name
- NCT01288742
- Testing
- Rosuvastatin, TMC435, Digoxin
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Tibotec Pharmaceuticals, Ireland
Non Invasive Ventilation, Patient Ventilator Interaction
Neurally Adjusted Ventilatory Assist for Non Invasive Ventilation and Patient-ventilator Interaction
The present study aims to compare various parameters reflecting patient-ventilator synchrony during standard pressure support (PS) and Neurally Adjusted Ventilatory assist (NAVA) in a group of patients receiving non invasive…
- Trial name
- NCT01074866
- Testing
- Neurally Adjusted Ventilatory Assist
- Where
- 4 sites in Belgium, Switzerland
- Volunteers
- 13 people
- Sponsor
- University Hospital, Geneva
Malaria
Drug-drug Interaction Study of Ganaplacide and Lumefantrine With Itraconazole
The study will assess the effect of multiple doses of itraconazole, a strong CYP3A4/5 inhibitor, on the PK of ganaplacide and lumefantrine in healthy participants.
- Trial name
- NCT05084651
- Testing
- Ganaplacide, Lumefantrine, Itraconazole
- Where
- United Kingdom
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Novartis Pharmaceuticals
Healthy
Drug Interaction Study to Asses Multiple Doses of ZD4054 (Zibotentan)
The purpose of the study is to to assess the effect of multiple oral doses of ZD4054 (Zibotentan) on the pharmacokinetics of a CYP450 3A Probe (midazolam) in healthy male subjects.
- Trial name
- NCT00709553
- Testing
- midazolam, ZD4054
- Where
- Germany
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Cancer
Multiple Interactive With Nutrition and Exercise Strategies in Frailty Cancer Patients
Due to the changes in lifestyle caused by the COVID-19, it is a priority to provide multi-interactive digital platforms and social media for nutrition and exercise programs for cancer patients.
- Trial name
- NCT04654637
- Testing
- Nutrition and Exercise Strategies
- Where
- Taiwan
- Volunteers
- 128 people
- Sponsor
- Tzu Chi University
Soft Tissue Sarcoma
Pharmacologic Interaction Between Ifosfamide and Aprepitant in Treated Patients With Soft Tissue Sarcoma
This trial is a multicentric study aiming to assess the evolution of the serum ifosfamide concentrations and its serum metabolites in patients treated for an Soft Tissue Sarcoma and co-exposed to Aprepitant.
- Trial name
- IPIAP-STM (NCT03514381)
- Testing
- Patients starting a treatment with Doxorubicin and Ifosfamide
- Where
- 3 sites in France
- Volunteers
- 59 people
- Sponsor
- Institut Claudius Regaud
Tobacco Use Disorder
Tobacco Zero: Interactive Tobacco Education for Teens
There have been a number of tobacco prevention programs developed and tested in the past few years, and some of the comprehensive programs have been promoted by the Office on Smoking and Health at the Centers for Disease Control…
- Trial name
- NCT00670995
- Testing
- Interactive Tobacco Education
- Where
- United States
- Volunteers
- 1,864 people, healthy volunteers welcome
- Sponsor
- Deschutes Research, Inc.
COVID, Drug Effect
Simulation of Risk of Adverse Drug Events Associated With the Initiation of Drugs Repurposed for the Treatment of COVID-19 in Adults With Polypharmacy Using Data From Large Medicare and Commercially Insured Populations
This retrospective study aims to perform a medication risk stratification using drug claims data and to simulate the impact of the addition of various repurposed drugs on the Medication Risk Score (MRS) in a health insurance…
- Conditions
- COVID, Drug Effect, Drug Interaction, Adverse Drug Event
- Trial name
- NCT04378881
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Tabula Rasa HealthCare
Below Knee Amputation
Use of an Interactive Video Game as Part of a New Amputee Rehabilitation Program
Purpose: The investigators wish to determine if a rehabilitation program for subjects with new, trans-tibial amputations that has the balance portion of the program augmented by the use of the Nintendo Wii fit ™ balance board…
- Trial name
- NCT01131819
- Testing
- Nintendo Wii fit ™ balance board
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- University of British Columbia
Chronic Low-back Pain
Online Physical Exercise for Chronic Low Back Pain
This study aims to evaluate the effects of technology-based interventions, specifically web-based platforms, on outcomes of patients with chronic low back pain.
- Trial name
- CLBPEO (NCT05895630)
- Testing
- Interactive physical exercise, Video physical exercise
- Where
- 2 sites in Canada
- Volunteers
- 57 people
- Sponsor
- Mathieu Roy
Hepatitis C Infection, Depression
Interaction Between Paroxetine and Telaprevir
Hepatitis C (HCV) infected patients are often in need for an antidepressant. The introduction of Direct Acting Antivirals such as telaprevir has greatly improved treatment outcome of HCV infected patients.Telaprevir has been…
- Trial name
- ROLEX (NCT01841502)
- Testing
- Paroxetine, telaprevir
- Where
- 7 sites in Netherlands
- Volunteers
- 3 people
- Sponsor
- Radboud University Medical Center
Obesity, Cardiovascular Risk
Long-term Effects of Lifestyle Intervention in Obesity and Genetic Influence
The purpose of the study is to determine the genetic influence on short-, middle- and longterm effects of an inpatient lifestyle therapy program in overweight and obese children and adolescents.
- Trial name
- LOGIC (NCT01067157)
- Testing
- LOGIC
- Where
- Germany
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Empowerment, Competence
COPE Program , Mental Health, Mother- Infant Interaction, Sense of Competence
The aim of the study is to: Evaluate the effect of creating opportunities for parent empowerment program on maternal sense of competence, mental health outcome and mother-infant interaction.
- Conditions
- Empowerment, Competence, Outcome, Interaction
- Trial name
- NCT06502730
- Testing
- Creating Opportunities for Parent Empowerment (COPE) Program
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Matrouh University
IgA Nephropathy (IgAN)
Exploring the Brain - Gut Microbiota - Kidney Interactive Damage Mechanisms Underlying Cognitive Decline in Patients With IgA Nephropathy Using Ultra-high Field Magnetic Resonance Imaging
IgA nephropathy (IgAN) is the most common primary glomerular disease worldwide. Its progression is often accompanied by cognitive decline, manifesting as multi-dimensional cognitive deficits in areas such as memory, attention…
- Trial name
- NCT07617402
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tang-Du Hospital
Women, Metabolism
Physical Activity Level and Hormonal Status on Energy Metabolism and Nutritional Responses
Obesity and its associated cardiometabolic comorbidities are a major health problem and although their prevalence is increasing in both men and women, evidence shows a faster increase in women, especially in those of childbearing…
- Trial name
- COCONUT (NCT05944653)
- Where
- France
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Renal Impairment, Gout
Evaluation of Colchicine and Nonsteroidal Anti-inflammatory Drug Combination Therapy and Renal Function in Gout Patients
Our findings are expected to provide real-world evidence of the renal-adverse effects of colchicine and NSAIDs combination therapy in patients with gout, which will guide healthcare professions in optimizing gout treatment…
- Conditions
- Renal Impairment, Gout, Colchicine Adverse Reaction, Nonsteroidals (NSAIDs)Toxicity
- Trial name
- NCT05006001
- Testing
- Colchicine and NSAID
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- En Chu Kong Hospital
Child Development
The Influence of Interactive Media on Child Development in Early Childhood
Introduction: In the last decade the prevalence of the use of interactive media (smartphone, tablet) by children has grown worldwide.
- Trial name
- IMD (NCT04831229)
- Testing
- Children will perform activities on interactive tablet, Children will perform passive on interactive tablet
- Where
- Brazil
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Federal University of the Valleys of Jequitinhonha and Mucuri
Eating Disorders, Maladaptive Personality Trait
MICBT for Non-underweight Adults With Eating Disorders
Eating disorders (ED) are severe but treatable conditions, but there are large margin for improvements in terms of efficacy and adherence.
- Conditions
- Eating Disorders, Maladaptive Personality Trait, Emotion Regulation, Personality
- Trial name
- MICBT-ED (NCT05503745)
- Testing
- CBT-F+MIT, CBT-E
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Centro Trattamento Integrato: Disturbi Alimentari e Obesita
Depression, Anxiety
SALSA (Health, Food and Sociability): Community Networks for Healthy Eating, Autonomy, and Social Interaction
Antecedents: Unwanted loneliness is associated with an increased risk of anxiety, depression, social isolation, and malnutrition.
- Conditions
- Depression, Anxiety, Social Support (Formal and Informal), Quality of Life (QOL)
- Trial name
- SALSA (NCT06800027)
- Testing
- SALSA group intervention: Going to lunch at the restaurant in a group and attending healthy eating workshops.
- Where
- Spain
- Volunteers
- 98 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
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