Clinical trials: Interhemispheric Inhibition
Stroke
Interaction Between the Brain Hemispheres - Key to Motor Recovery After Stroke
Rationale: Acute stroke leaves many patients with functional deficits, of which upper extremity motor impairment is one of the most disabling.
- Trial name
- InterAct (NCT06381388)
- Testing
- cTBS
- Where
- Netherlands
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Jord Vink
Healthy
Studying Use-Dependent Plasticity
Recent studies suggest that when patients learn a new motor movement, it may cause a change in the way the nerves act in the area of the brain that controls that movement. This change is called use-dependent plasticity.
- Trial name
- NCT00067223
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Neurophysiology, Physiology
Functional Implication of Corpus Callosum in Voluntary Strength in COPD Patients
Patients with COPD have lower capability of activating their muscles. At the cortical level, force production is not only controlled by contralateral primary motor cortex but also by ipsilateral motor cortex.
- Trial name
- NCT03807258
- Testing
- Transcranial magnetic stimulation (TMS)
- Where
- 2 sites in France
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- 5 Santé
Cerebrovascular Accident, Healthy
Interhemispheric Interactions Associated With Performance of Voluntary Movements in Patients With Stroke Motor Disability
This study will use transcranial magnetic stimulation (TMS) to identify interactions between the unaffected and affected side of the brain in stroke patients.
- Trial name
- NCT00029718
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Anterior Cruciate Ligament Injuries
Deficit in Quadriceps Voluntary Activation After Anterior Cruciate Ligament Reconstruction: Roles of the "Learned Non-use" Paradigm and the Interhemispheric Inhibition
Anterior cruciate ligament (ACL) tear is mainly caused by sport injuries. 40% of injuries are attributed to noncontact mechanisms involving pivoting.
- Trial name
- AQUARIUS (NCT04837417)
- Testing
- Pathologic group
- Where
- 2 sites in Italy
- Volunteers
- 10 people
- Sponsor
- Istituto Auxologico Italiano
Interhemispheric Inhibition
Interaction of Right and Left Brain Hemispheres in Learning Precision Hand Movements
This study will examine how the two sides of the brain interact when learning precision hand movements. Both sides of the brain are active when a person performs an accurate hand movement.
- Trial name
- NCT00295568
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Stroke
Interhemispheric Inhibitory Interactions
After a stroke the excitability of the brain decreases on the stroke side and increases on the opposite, non-stroke side. These changes make use of the stroke-affected arm difficult and slow recovery.
- Trial name
- InHIb (NCT01371409)
- Testing
- continuous theta burst stimulation
- Where
- Canada
- Volunteers
- 49 people
- Sponsor
- Canadian Institutes of Health Research (CIHR)
Cortico-cortical Paired Associative Stimulation
The Use of Dual-coil Transcranial Magnetic Stimulation to Measure and Modulate Poststroke Interhemispheric Inhibition.
Objectives: This project will (1) establish the test-retest reliability of a novel transcranial magnetic stimulation-electroencephalography (TMS-EEG) interhemispheric inhibition (IHI) measure and (2) validate it against the…
- Trial name
- NCT07431749
- Testing
- Dual coil transcranial magnetic stimulation
- Where
- 2 sites in Hong Kong
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University