Clinical trials: Interleukin-6
Inflammation
Comparison of Two Anaesthetics on Brain During Brain Tumour Surgery
Anaesthesia and surgical stress during craniotomy can lead to brain damage and activation of inflammatory response. Consequently inflammatory cytokines (IL6, IL8, IL10) are released.
- Trial name
- NCT02229201
- Testing
- Propofol, Sevoflurane
- Where
- Slovenia
- Volunteers
- 40 people
- Sponsor
- University Medical Centre Ljubljana
Circadian Rhythm
Impact of Evening Snacks and Pre-Breakfast Intake on Sleep, Heart Rate Variability, and Stress Markers in Healthy Males.
The body has a natural 24-hour rhythm. This rhythm affects factors like body temperature, sleep and Heart Rate Variability (HRV). Dietary choices influence these physiological processes of the body.
- Trial name
- NCT06480305
- Testing
- Post dinner snack, Pre-Breakfast-1, Pre-Breakfast-2
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Obstructive Sleep Apnea
A Pilot Study of Biomarkers in Obstructive Sleep Apnea
Obstructive sleep apnea (OSA) is common and is a risk factor for postoperative complications, including respiratory and cardiac events and delirium.
- Trial name
- Cytokine OSA (NCT02325687)
- Testing
- Lumbar Puncture (Standard-of-Care)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Hospital for Special Surgery, New York
Sedentary Employees, Postprandial Oxidation and inflammation
The Effects of Brown Rice Compared to White Rice on Postprandial Changes in IL-6 and MDA Levels in Sedentary Workers
The goal of this clinical trial is to learn if brown rice and white rice affect oxidative stress and inflammation in office workers who don't exercise much.
- Trial name
- NCT06780618
- Testing
- RICE
- Where
- Indonesia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Suicidal Ideation
Correlation of Campbell Score With Suicidal Ideation
The Campbell Score is a blood based means of assessing molecules believed to be associated with suicidal ideation and in some cases successful suicide.
- Trial name
- NCT04606875
- Testing
- Campbell Score
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Therapeutic Solutions International
Traumatic Brain Injury
Comparison Between Effect of Vitamin D Versus Dexmedetomidine in Patients with Head Trauma Using Interleukin 6
in this study the investigators compare between the neuroprotective effect of vitamin d versus dexmedetomidine in patients with traumatic brain injury using interleukin 6 as inflammatory biomarker
- Trial name
- NCT06565338
- Testing
- Dexmedetomidine, Vitamin D3
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Minia University
PCO
Effect of Metformin and Combination of Olive Oil Plus Nutritional Supplements on Inflammatory Markers IL-6 and IL-8 in PCOS.
The investigators aim is to conduct randomized clinical trial, to determine the effects of metformin and combination of olive oil plus nutritional supplements on inflammatory markers IL-8 and IL6 in polycystic ovarian syndrome…
- Trial name
- NCT05952349
- Testing
- OLIVE OIL 5ML/5MG (BD) NUTRITIONAL SACHET 2100MG (BD), Metformin (1000 mg Twice a day)
- Where
- Pakistan
- Volunteers
- 88 people
- Sponsor
- Khyber Medical University Peshawar
COVID-19 Pneumonia
Tocilizumab in COVID-19 Pneumonia (TOCIVID-19)
This study project includes a single-arm phase 2 study and a parallel cohort study, enrolling patients with COVID-19 pneumonia.
- Trial name
- TOCIVID-19 (NCT04317092)
- Testing
- Tocilizumab Injection
- Where
- 27 sites in Italy
- Volunteers
- 402 people
- Sponsor
- National Cancer Institute, Naples
Critical Illness, Muscle Wasting
Leucine-enriched Branched-chain Amino Acid on Muscle Thickness, Interleukin-6, SOFA Score in Critical Illness
The goal of this clinical trial study is to test effects of leucine-enriched branched-chain amino acid (BCAA) in critically ill patients.
- Trial name
- SOFA (NCT06167772)
- Testing
- BCAA, Standard nutrition, Standard physiotherapy
- Where
- 2 sites in Indonesia
- Volunteers
- 40 people
- Sponsor
- Universitas Indonesia
Sepsis, Septic Shock
Multicenter Symphony IL-6 Monitoring Sepsis ICU Study
The primary objective of this study is to establish an IL-6 concentration cutoff and optimal time point(s) for using Symphony IL-6 that predict 28-day mortality in patients who are admitted or are intended to be admitted to the…
- Trial name
- SYMON (NCT06181604)
- Where
- 7 sites in United States
- Volunteers
- 143 people
- Sponsor
- Bluejay Diagnostics, Inc.
Diabetes Mellitus, Type 2, Obesity
Role of Interleukin-6 in Exercise
The purpose of the study is to understand the role of interleukin-6 during physical activity in patients with type 2 diabetes.
- Trial name
- Exil-6 (NCT01073826)
- Testing
- Sport, Tocilizumab, Sitagliptin
- Where
- Switzerland
- Volunteers
- 56 people
- Sponsor
- University of Zurich
Anemia of Chronic Disease
Efficacy of NOX-H94 on Anemia of Chronic Disease in Patients With Cancer
This study is conducted to determine the safety, tolerability, and efficacy of NOX-H94 in patients with anemia of chronic disease (ACD).
- Trial name
- NCT01691040
- Testing
- NOX-H94
- Where
- 11 sites in Austria, Bulgaria and 1 more
- Volunteers
- 12 people
- Sponsor
- TME Pharma AG
Lung Cancer (Diagnosis)
Effect of Apneic Oxygenation of the Non-ventilated Lung During Lung Cancer Surgery.
This study investigates the effect of apneic oxygenation of the non-ventilated lung on local and systemic inflammatory response during lung cancer surgery.
- Trial name
- NCT07393490
- Testing
- Apnoeic Oxygenation, Standard Ventilation
- Where
- Croatia
- Volunteers
- 56 people
- Sponsor
- Osijek University Hospital
Obstructive Sleep Apnea, Cardiovascular Diseases
Obstructive Sleep Apnoea and Cardiac Arrhythmias
This study is a prevelance trial looking at how sleep apnoea affects the heart especially heart rhythms. Previous research shows that patients suffering from sleep apnoea are much more likely to get heart disease and abnormal…
- Conditions
- Obstructive Sleep Apnea, Cardiovascular Diseases, Arrhythmia, Atrial Fibrillation New Onset
- Trial name
- OSCA (NCT03866148)
- Testing
- Reveal LINQ
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- University Hospitals Coventry and Warwickshire NHS Trust
Acute Ischemic Stroke, Large Vessel Occlusion
Inflammatory Markers and Prognosis After Cerebral Thrombectomy in Large Vessel Occlusion
The goal of this observational study is to describe the local change in interleukin-6 (IL-6) across a blood clot in adults with acute ischemic stroke caused by anterior circulation large vessel occlusion who are undergoing…
- Trial name
- IMPACT-LVO (NCT07754942)
- Testing
- Prospective Mechanical Thrombectomy Cohort
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Zhongshan Hospital Xiamen University
Analgesia, Surgical Procedure, Unspecified
TLIP Block Versus Modified TLIP Block for Posterior Decompression and Stabilization Surgery
This study aimed to compare the analgesia effectivity of TLIP and modified TLIP block in Posterior Lumbar Decompression and Stabilization Surgery Perioperatively.
- Trial name
- NCT05104203
- Testing
- Thoracolumbar Interfascial Plane block, Modified Thorcolumbar Interfascial Plane block
- Where
- Indonesia
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Periodontitis Stage II
The Effect of Locally Dilvered Ciprofloxacine Loaded Injectable Platelet-rich Fibrin as an Adjunct to Non-surgical Periodontal Therapy on the Gingival Crevicular Level of Interleukin 6
Sixty periodontally diseased patients will be enrolled in the study. After the patients are randomly divided into one of three treated groups, group 1 (n=20), SRP only; group 2 (n=20), SRP + i-PRF; and group 3 (n=20), P +…
- Trial name
- PRF & CIP-iPRF (NCT06968286)
- Testing
- SRP, SRP+Injectable platelet rich fibrin, SRP+ciprofloxacine loaded iPRF
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Bone Marrow Diseases
Cytokine Gene Polymorphisms in Bone Marrow Failure
This study will examine whether cytokine gene polymorphisms affect the progression or response to therapy of bone marrow failure disorders.
- Trial name
- NCT00085670
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Pulmonary Tuberculosis
Effect of Vitamin D and Zinc Supplementation on Inflammatory Biomarkers in Pulmonary Tuberculosis Patients
This study evaluates the effect of combined Vitamin D and Zinc supplementation on inflammatory biomarkers in pulmonary tuberculosis (TB) patients during the intensive phase of treatment.
- Trial name
- NCT07899138
- Testing
- Vitamin D (Cholecalciferol ), Zinc (zinc sulphate)
- Where
- Indonesia
- Volunteers
- 32 people
- Sponsor
- Hasanuddin University