Clinical trials: Interleukin-6 Inhibition
Rheumatoid Arthritis, Inflammation
Effects of Interleukin-6 Inhibition on Vascular, Endothelial and Left Ventricular Function in Rheumatoid Arthritis
Recent studies show beneficial effect of the inhibition of interleukin-6 (IL-6) activity on vascular and left ventricular (LV) function.
- Trial name
- NCT03288584
- Testing
- Tocilizumab (Actemra®), Other biological agent, Corticosteroid and non-biological agents.
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Athens
Autoantibodies, Interleukin-6
Characterization of Natural IL-6 Inhibition in Healthy Individuals
The aim of the project is to investigate whether or not there are any difference in cardiometabolic outcomes in individuals with high or low levels of c-aAb against interleukin-6 (IL-6).
- Trial name
- FIDI (NCT05867524)
- Testing
- Oral Glucose Tolerance Test, Cycling test
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Interleukin-6 Inhibition, Physical Stress
Acute Exercise and NK Cell Regulation in Tissue and Circulation After IL-6R Blockade
The study is a randomized controlled trial studying the acute effect of intense aerobic exercise upon NK (Natural Killer) cell activation and appetite-regulation in human participants with or without concommitant IL-6R receptor…
- Conditions
- Interleukin-6 Inhibition, Physical Stress, Appetitive Behavior
- Trial name
- NCT04616235
- Testing
- Tocilizumab Injectable Product, Saline 0.9% 100 ml NaCl 0.9% will be infused over 1 hour
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet