Clinical trials: Intermediate Coronary Lesions
Aortic Stenosis
OpSens PRIME CLASS
In this study it is aimed to determine the diagnostic value of physiological measurements in the presence of aortic stenosis, and whether these are more accurate than angiographic assessment.
- Trial name
- NCT05070130
- Testing
- dPR and FFR
- Where
- 5 sites in Spain
- Volunteers
- 32 people
- Sponsor
- Opsens, Inc.
Ischemic Heart Disease
Comparison Between Everolimus-eluting Stent (EES) and Sirolimus-eluting Stent (SES) in the Bifurcation Lesion
In study-1, the purpose of this study is to compare the long-term outcome of provisional stenting between EES and SES deployment.
- Trial name
- J-REVERSE (NCT01266239)
- Testing
- kissing balloon inflation, EES vs. SES
- Where
- 5 sites in Japan
- Volunteers
- 300 people
- Sponsor
- Shin Yukuhashi Hospital
Coronary Artery Disease
A Randomized Comparison of Clinical Outcomes Between Everolimus-eluting Bioresorbable Vascular Scaffold Versus Everolimus-eluting Metallic Stent in Long Coronary Lesions
PCI of diffuse long coronary lesions still remains challenging because of relatively high risk of in-stent restenosis and stent thrombosis compared to short coronary lesions.
- Trial name
- NCT02796157
- Testing
- PCI with Absorb everolimus-eluting bioresorbable vascular scaffold, PCI with Xience everolimus-eluting metallic stent
- Where
- South Korea
- Volunteers
- 950 people
- Sponsor
- Yonsei University
Myocardial Ischemia
Multimodality Investigation of Intermediate Culprit Lesion With Negative FFR in NSTE-ACS
Ten-fifteen percent of acute coronary syndromes without ST-segment elevation (NSTE-ACS) are caused by intermediate lesions without signs of unstable plaque.
- Trial name
- SHERLOCK (NCT03205514)
- Testing
- NSTE-ACS with intermediate stenosis and negative FFR
- Where
- Italy
- Volunteers
- 35 people
- Sponsor
- University Hospital of Ferrara
Coronary Disease
OCT Measures Predicting FFR
Background: the decision-making process of patients with angiographically-intermediate coronary lesions (ICL) is clinically challenging and may benefit from adjunctive invasive techniques.
- Trial name
- OMEF (NCT03573388)
- Testing
- Optical coherence tomography (OCT)
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- Catholic University of the Sacred Heart