Clinical trials: Intermittent Fasting
Weight Loss, Time Restricted Feeding
TRE: Microbiome, Metabolic Health and Bone
In the Time-Restricted Eating: Microbiome and Bone (TREMBO) study, the primary goal is to determine the effect of time-restricted eating with caloric restriction compared to caloric restriction alone on bone health, as well as…
- Conditions
- Weight Loss, Time Restricted Feeding, Bone Loss
- Trial name
- TREMBO (NCT05548517)
- Testing
- Time Restricted Eating (TRE), Calorie Restriction
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Mild Cognitive Impairment, Alzheimer Disease
TREAD: Time Restricted Eating Intervention for Alzheimer's Disease
The goal of this clinical trial is to learn if restricting the time of eating to allow for prolonged fasting at night may reduce sleep disturbances, cognitive decay, and pathology in patients diagnosed with Mild Cognitive…
- Conditions
- Mild Cognitive Impairment, Alzheimer Disease, Alzheimer's Disease
- Trial name
- TREAD (NCT06548191)
- Testing
- Time-restricted eating
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Healthy
Effects of Time-Restricted Fasting on the Postprandial Glycemic Responses
The goal of this clinical trial is to investigate whether fasting timing has a significant effect on postprandial glycemic responses in healthy adults. The main questions it aims to answer are: 1.
- Trial name
- NCT05913635
- Testing
- Consumption of lunch and dinner, with no breakfast, Consumption of breakfast and lunch, with no dinner
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Fudan University
Time Restricted Eating, Obesity
Time-restricted Eating Acceptability, Efficacy and Safety in Obesity
A randomized controlled trial to determine adherence, acceptability and safety of time restricted eating (TRE) in healthy, sedentary, free-living adults with obesity between the ages of 19-65 years when following 16:8 TRE for 8…
- Trial name
- NCT06695988
- Testing
- Time Restricted Eating
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Mississippi, Oxford
Physical Exercise, Time Restricted Eating
Effect of Time-restricted Eating and Endurance Training on Markers of the Health of Women and Men
The aim of this project is to demonstrate the synergistic effect of TRE and NW training on health indicators for older women. The women will be divided into four groups, i.e.
- Conditions
- Physical Exercise, Time Restricted Eating, Mental Health Wellness 1, Wellbeing
- Trial name
- NCT05229835
- Testing
- Time restricted eating and exercise
- Where
- Poland
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Medical University of Gdansk
Diabetes, Hypertension
Impact of Intermittent Fasting and Mediterranean Diet on the Physical Health of the Elderly
The prevalence of chronic diseases is increasing globally. In recent years, intermittent fasting has emerged as an effective dietary pattern against some of the most common chronic diseases in the elderly, alongside the…
- Conditions
- Diabetes, Hypertension, Dyslipidemias, Obesity
- Trial name
- FASTMED (NCT06480669)
- Testing
- Time Restricted Feeding, Mediterranean Diet
- Where
- Spain
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza
Gestational Diabetes, Gestational Diabetes Mellitus in Pregnancy
Manchester Intermittent Diet in Gestational Diabetes Acceptability Study
A two-arm non-blinded randomised feasibility protocol trial designed to assess the feasibility, safety, and acceptability of an intermittent low energy diet (ILED) vs best National Health Service (NHS) care in women with…
- Conditions
- Gestational Diabetes, Gestational Diabetes Mellitus in Pregnancy, Intermittent Fasting, Pregnancy Related
- Trial name
- MIDDAS-GDM (NCT05344066)
- Testing
- Best NHS Care, Intermittent Low Energy Diet
- Where
- United Kingdom
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Manchester University NHS Foundation Trust
Dietary Exposure
Time-restricted Feeding Improves Basal Fat Oxidation and Body Composition But Not Fat Oxidation During Exercise
Time-restricted feeding is one of the IF models with significant advantages beyond other IF models, such as simplicity and flexibility, where individuals limit their eating window to specific hours of the day, with a fasting…
- Trial name
- NCT06498102
- Testing
- Intermittent Fasting: Time Restricted Feeding During 6 Weeks
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Weight Loss
The Effect of Time Restricted Feeding on Fat Mass in Overweight Women
Participants will complete a one-month intervention where they are will restrict their daily food intake to an 8-hour time period, i.e., between 1200 to 2000 hours.
- Trial name
- NCT02629900
- Testing
- Time restricted feeding
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Western Ontario, Canada
Overweight and Obesity
Could a Time-restricted Diet Compete With a Calorie-restricted 6-meal Diet?
The prevalence of obesity and obesity-related diseases are on the rise worldwide. The widely accepted approach in dietary treatment of obesity is the calorie-restricted three meals-three snacks a day diet; however, alternative…
- Trial name
- NCT06364475
- Testing
- 16:8 Time-Restricted Intermittent Fasting Group, Energy-Restricted Six-Meal Group
- Where
- Turkey (Türkiye)
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Obesity, Abdominal
The Impact Of An Intermittent Energy Restricted Diet On Insulin Sensitivity In Men and Women With Central Obesity
An intermittent energy restricted (IER) diet may modify cardio-metabolic disease risk factors compared to an energy-matched continuous energy restricted (CER) diet.
- Trial name
- Met-IER (NCT02679989)
- Testing
- Intermittent Energy Restriction, Continuous Energy Restriction
- Where
- United Kingdom
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- King's College London
Obesity, Overweight
The Acute Effects of Caloric Restriction on Anthropometrics, Metabolism, and Cardiovascular Health in Overweight Adults
The purpose of this study is to document the efficacy of a 3 day intermittent fasting/caloric restriction (IF/CR) using the Plexus® 3 day reset program on body weight as well as regulatory parameters of metabolism and metabolic…
- Conditions
- Obesity, Overweight, Intermittent Fasting
- Trial name
- NCT05422391
- Testing
- 3 day caloric restriction/metabolic reset
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Skidmore College
Time Restricted Feeding
Prolonged Overnight Fast, Energy Metabolism and Skeletal Muscle Anabolic Sensitivity
Recent research shows that timing of nutritional intake and daily periods of fasting may have important health effects. In humans, limiting daily food intake to a narrow window (typically ~8 hours) can bring about some beneficial…
- Trial name
- NCT05420181
- Testing
- Short 10hr fast, Long 16h fast
- Where
- United Kingdom
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Diet, Healthy, Body Weight
Diet, Body Composition, Lifestyle and Cardiovascular Health of Healthy and Active Adults From Slovenia
There is objective need to evaluate the differences in dietary intake (DI), body composition (BC), lifestyle (LS) and cardiovascular diseases (CVD) risk factors between healthy and active vegetarinas (VEG) and non vegetarians…
- Conditions
- Diet, Healthy, Body Weight, Time Restricted Feeding, Sleep
- Trial name
- SloLifestyle (NCT04379622)
- Testing
- Dietary intake, body composition, lifestyle, and CVD risk factors
- Where
- Slovenia
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Barbara Jakše s.p.
Healthy Diet, Fasting, Intermittent
Fasting Time Effects in Time-Restricted Eating (FaTE-TRE)
Over the past century, lifestyles and eating habits have rapidly changed, helping to increase the onset of conditions such as obesity, metabolic syndrome and the risk of cardiovascular and metabolic diseases such as diabetes.
- Trial name
- FaTE-TRE (NCT04503005)
- Testing
- Time Restricted Eating
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Padova
Body Weight Changes
Pilot Study on the Impact of the Mediterranean Diet and Intermittent Fasting
This clinical trial attempts to evaluate the feasibility and acceptability of an intervention combining intermittent fasting and the Mediterranean diet guidelines vs an comparative intervention combining intermittent fasting but…
- Trial name
- NCT04185948
- Testing
- Mediterranean diet guidelines plus intermittent fasting, UK Eatwell guidelines plus intermittent fasting
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Anti-Psychotic, Management of Manifestations of Psychotic Disorders
Assessment of Intra-subject Variability in the Bioavailability of Chlorpromazine Hydrochloride
Cycle Pharmaceuticals Ltd. (Cycle) is developing an oral tablet formulation of Chlorpromazine Hydrochloride and intends to conduct bioequivalence trials to demonstrate its similarity to the RLD.
- Conditions
- Anti-Psychotic, Management of Manifestations of Psychotic Disorders, Treatment of Schizophrenia, Control Nausea and Vomiting
- Trial name
- NCT02943213
- Testing
- Chlorpromazine Hydrochloride
- Where
- South Africa
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cycle Pharmaceuticals Ltd.
Appetite and General Nutritional Disorders
The Effects of a High Protein Breakfast on Appetite and Sleep in Young Adults
The purpose of this study is to examine the effects of breakfast skipping (SKIP) vs. the consumption of a high protein solid (HP-S) breakfast vs.
- Trial name
- NCT03031132
- Testing
- HP-Beverage Breakfast, HP-Solid Breakfast, Breakfast Skipping
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Purdue University
Aging
The Effect of Time-restricted Feeding on Physiological Function in Middle-aged and Older Adults
The purpose of this study is to assess the safety and efficacy of time-restricted feeding (eating within an 8-hour window) for improving physiological function (vascular, motor, cognitive and metabolic function) in healthy…
- Trial name
- NCT02970188
- Testing
- Time Restricted Feeding
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder
Glucose and Lipid Metabolism
The Effects of 24-hour Fasting or Carbohydrate Restriction on Postprandial Metabolic Responses
Most individuals spend the majority of the day in a fed state, making postprandial blood glucose and lipid regulation a central component of metabolic health.
- Trial name
- NCT07250191
- Testing
- Fasting, Carbohydrate restriction
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Bath