Clinical trials: Intermittent Fasting, open to volunteers
Obesity
Modified Intermittent Eating on Weight Loss (INTEREST-3 Trial)
Calorie restriction (CR) is the most important treatment for weighting loss. In recent years, two novel types of intermittent fasting recently have gained more attention: the 5:2 diet and time-restricted eating (TRE).
- Trial name
- INTEREST-3 (NCT06302803)
- Testing
- Intermittent fasting plus time-restricted eating, Calorie restriction
- Where
- China
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Energy Deficiency Due to Short-term Fasting, Hormonal Contraception
Energy Deficiency on Hormones in Contraceptive Users
The purpose of the present study is to characterize the endocrine and metabolic responses to a modest, short-term energy deficiency (~250 kcal/day) across the menstrual cycle in recreationally active women using different…
- Trial name
- NCT07651800
- Testing
- Energy Deficiency of approximately ~250 kcal/day
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Southern California
Vaccination, Immunosenescence
VITAL: Vaccination, Immunity, Time-restricted Eating, Aging and Lifestyle
The aim of this study is to investigate the effects of a four-week time-restricted eating (TRE) intervention on autophagy, immune function, and vaccine response to a seasonal influenza and COVID-19 vaccines in older healthy…
- Conditions
- Vaccination, Immunosenescence, Metabolism
- Trial name
- VITAL (NCT07000708)
- Testing
- TRE: Time-restricted eating
- Where
- Germany
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Asthma Management, Time Restricted Eating
Investigating the Impact of Early Time-Restricted Eating on Health Outcomes and Quality of Life in Adults With Mild Controlled Asthma Compared to Healthy Adults
This study aims to explore how early time-restricted eating (eTRE) - where all daily meals are eaten within a specific time window - affects health and quality of life in adults.
- Trial name
- eTRE (NCT07345572)
- Testing
- Early Time-Restricted Eating (eTRE) and Habitual Diet (HD), Habitual Diet (HD) and Early Time-Restricted Eating (eTRE)
- Where
- United Kingdom
- Volunteers
- 36 people
- Sponsor
- De Montfort University
NAFLD, Obesity
Intermittent Fasting, Mediterranean Diet and NAFLD
This study aims to evaluate the effects of Intermittent Fasting (IF) 14/10 compared with the Low Glycemic Index Mediterranean Diet on NAFLD.
- Conditions
- NAFLD, Obesity, Intermittent Fasting, Mediterranean Diet
- Trial name
- RC2024-21 (NCT06615817)
- Testing
- Intermittent Fasting
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
Fatty Liver, Intermittent Fasting
Intermittent Fasting for NAFLD in Adults
NAFLD is a growing threat to public health. Currently, there is a significant need for highly effective treatments for NAFLD. Non-obese NAFLD (BMI<30kg/m2) is an increasingly recognized condition, sometimes described as "lean…
- Conditions
- Fatty Liver, Intermittent Fasting, Fatty Liver, Nonalcoholic, Non-Alcoholic Fatty Liver Disease
- Trial name
- NCT04899102
- Testing
- Time-Restricted, Intermittent Fasting
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Massachusetts General Hospital
Evaluating, Intermittent Fasting
Evaluating Intermittent Fasting In Individuals At High Risk ForPancreatic Cancer Undergoing Screening
To learn whether an eating pattern called intermittent fasting (IF) is tolerable and feasible for individuals at high risk of pancreatic cancer and whether IF is associated with changes in biological markers, including metabolic…
- Conditions
- Evaluating, Intermittent Fasting, Pancreatic Cancer
- Trial name
- NCT07513116
- Testing
- intermittent fasting
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- M.D. Anderson Cancer Center
Normal and Overweight Individuals at High-risk of Diabetes
The Metabolic Effects of Intermittent Fasting
Caloric restriction has beneficial metabolic effects in humans including weight loss and improvement in blood pressure and lipid levels.
- Trial name
- NCT05722873
- Testing
- Fasting arm, Weight maintenance, Counseling
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Hypertension
The Combined Effect of the Mediterranean Diet and Intermittent Fasting on Hypertension
Hypertension (HT) is an important risk factor for cardiovascular diseases (CVD) and death. Approximately 16.9 million people in Turkey have HT. Nutritional habits play an important role in the development of HT.
- Trial name
- NCT07189637
- Testing
- Face-to-face nutrition education, Intermittent Fasting Diet, Mediterranean Diet
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Nadide Gizem Tarakci Filiz
Obesity; Impaired Glucose Regulation; Prediabetes; Type 2 Diabetes Mellitus
Time-Restricted Eating and Staple Food Reduction Combined With App-Supported Exercise for Weight and Glycemic Control
This multicenter, three-arm randomized controlled trial will evaluate the effects of early time-restricted eating and staple food reduction, each combined with an app-supported exercise intervention, on body weight and glycemic…
- Trial name
- TRE-SFR-EX (NCT07726615)
- Testing
- App-Supported Exercise Intervention, Staple Food Reduction, Early Time-Restricted Eating
- Volunteers
- 300 people
- Sponsor
- Peking University
Spinal Cord Injury, Depression - Major Depressive Disorder
Intermittent Fasting for Inflammation and Depression in Spinal Cord Injury
Depression and chronic inflammation are common problems for people with spinal cord injury (SCI). Inflammation has been shown to influence depression which may make it an important treatment target.
- Trial name
- NCT06807528
- Testing
- Intermittent fasting, Behavioral Support Strategies
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
MASLD (Metabolic Dysfunction-Associated Steatotic Liver Disease)
Efficacy of 12-week Daytime Restricted Eating on Hepatic Steatosis of Obesity
The objective of this study is to demonstrate that an < or equal to 8-hour time-restricted eating (i.e., fasting for at least 16 hours every day), not focusing on reducing caloric intake, reduces intra-hepatic fat in patients…
- Trial name
- CHRONOSTEATOSI (NCT07378072)
- Testing
- Time Restricted Eating, Usual care only
- Where
- 9 sites in France
- Volunteers
- 72 people
- Sponsor
- Nantes University Hospital
Rectal Cancer Stage II, Rectal Cancer Stage III
Effect of Meal Timing During Cancer Treatment in Patients in Alaska: A Randomized Clinical Trial
The goal of this clinical trial is to test meal-timing as a novel and sustainable interventional approach during cancer treatment to improve therapeutic response and metabolic health in an understudied population.
- Conditions
- Rectal Cancer Stage II, Rectal Cancer Stage III, Breast Cancer Stage I, Rectal Cancer Stage IV
- Trial name
- NCT06802172
- Testing
- Time-restricted eating, Questionnaire Administration, Biospecimen Collection
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Fred Hutchinson Cancer Center
Time Restricted Eating, Diet, Mediterranean
Healthy Lifestyles for Bipolar Disorder
The goal of this clinical trial is to compare the effects of two different healthy lifestyles on outcomes for those with bipolar disorder.
- Trial name
- HL (NCT06188754)
- Testing
- Time restricted eating, Mediterranean diet
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of California, Berkeley
Childhood Obesity, Childhood Obesity Pevention
Effectiveness of School-Based Time-Restricted Eating for the Prevention and Control of Obesity in Children
Childhood obesity has become a major global public health challenge. Obesity can not only affects children's physical and mental health during childhood but may also persist into adulthood, significantly increasing the risk of…
- Trial name
- SCHOOL-TRE (NCT07184281)
- Testing
- 12-hour time-restricted eating, health education
- Where
- 2 sites in China
- Volunteers
- 1,380 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Soochow University
Ovary Cancer, Endometrial Cancer
Alternate Day Fasting After Surgery for Patients Undergoing Chemotherapy
Endometrial cancer is the most common gynecologic cancer and ovarian cancer is the most lethal. The management of both advanced cancers is a combination of chemotherapy and surgery.
- Conditions
- Ovary Cancer, Endometrial Cancer, Uterine Cancer
- Trial name
- FAST (NCT05990426)
- Testing
- FAST Intervention
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Northwestern University
Hypertension, Breakfast Skipper
Early Time-Restricted Eating for Cardiovascular Health
This study will examine whether eating earlier in the day within a consistent 8-hour eating window can improve heart and blood vessel health in older adults with high blood pressure who often skip breakfast.
- Trial name
- ALIGN (NCT07634926)
- Testing
- Early Time-Restricted Eating (eTRE)
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Alabama at Birmingham
Night Shift Work, Time Restricted Eating
Optimization of Chrononutrition to Reduce the Risk of Disease in Shift Workers
In this randomized controlled trial, the investigators will assess the health impacts of optimizing the timing of dietary consumption in nurses and nursing assistants who work night shifts, have a habitual eating window of 14…
- Conditions
- Night Shift Work, Time Restricted Eating, Overweight, Obesity
- Trial name
- SHIFT (NCT06891352)
- Testing
- Dietary Monitoring, Time-Restricted Eating (TRE), Time-Restricted Eating with a Low-Glycemic Snack (TRE-LGS)
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Salk Institute for Biological Studies
Critical Illness, Fasting State
Ketosis, Immune Function and Metabolic Adaptation in Response to Short-term Fasting in Critical Illness
KETO-FAST is a pre-planned translational substudy of the FAST-ICU cluster-randomized cross-over trial. The substudy will characterize ketone body production and associated metabolic, autophagy-related, and immune cellular…
- Conditions
- Critical Illness, Fasting State, Ketosis, Nutrition
- Trial name
- KETO-FAST (NCT07738536)
- Testing
- Delayed nutrition, Standard nutrition, Fasting
- Where
- Sweden
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Karolinska University Hospital
Epithelial Ovarian Cancer
Fasting During Neoadjuvant Chemotherapy in Patient With Epithelial Ovarian Cancer
The goal of this clinical trial is to see if timed fasting (periods of time that you don't eat) in participants who are receiving chemotherapy prior to surgery is achievable, safe and can improve quality of life, symptoms and…
- Trial name
- NCT06386887
- Testing
- Intermittent Fasting, Neoadjuvant chemotherapy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Case Comprehensive Cancer Center