Clinical trials: Internal Hemorrhoid
Internal Hemorrhoid
Outcomes and Quality of Life Following Rectal Artery Embolization for Bleeding Internal Hemorrhoids
This study will assess how effective and safe rectal artery embolization works to treat symptomatic bleeding predominant internal hemorrhoids.
- Trial name
- HEMBO-1 (NCT06106269)
- Testing
- Rectal Artery Embolization
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
Hemorrhoids, Postoperative Pain
Oral Nifedipine Versus Placebo for Pain and Healing After Hemorrhoidectomy
The goal of this clinical trial is to evaluate whether oral nifedipine reduces postoperative pain and improves wound healing after hemorrhoidectomy in adult patients aged 18-65 years undergoing elective surgery for grade III or…
- Conditions
- Hemorrhoids, Postoperative Pain, Wound Healing, Analgesia
- Trial name
- NIFEDIPINE-HD (NCT07659665)
- Testing
- Nifedipine 20 Mg
- Where
- Yemen
- Volunteers
- 100 people
- Sponsor
- Sana'a University
Internal Hemorrhoid, Rectal Prolapse
Cap-assisted Endoscopic Sclerotherapy for Internal Hemorrhoids and Rectal Prolapse
This clinical trial aims to evaluate the efficacy and safety of long needle and short needle in the treatment of internal hemorrhoids and rectal prolapse through CAES (Cap-assisted endoscopic sclerotherapy).
- Trial name
- NCT03917056
- Testing
- Cap-assisted endoscopic sclerotherapy using long needle, Cap-assisted endoscopic sclerotherapy using short needle
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- The Second Hospital of Nanjing Medical University
Grade II Internal Hemorrhoids With Bleeding
A Phase III Clinical Trial Evaluating the Efficacy and Safety of TriThien Duoc Capsules in Grade II Internal Haemorrhoids Patients With Bleeding Compared to Diosmin.
A Phase III, randomized, double-blind, placebo-controlled clinical trial has been conducted to evaluate the efficacy and safety of Trĩ Thiên Dược capsules in people with grade II internal hemorrhoids with bleeding.
- Trial name
- NCT07369635
- Testing
- Intervention Group: Tri Thien Duoc Capsules, Control group (diosmin)
- Where
- Vietnam
- Volunteers
- 172 people
- Sponsor
- Hanoi Medical University
Grade/Stage I Hemorrhoids, Prolapsed Grade II Internal Haemorrhoid
A Multicenter Prospective Clinical Study of Endoscopic Foam Sclerotherapy for Internal Hemorrhoids
"Internal hemorrhoid" affects the quality of life due to hemorrhage and prolapse as a common and frequently-occurring disease. Endoscopic sclerosing agent injection has replaced traditional surgery and become the most commonly…
- Conditions
- Grade/Stage I Hemorrhoids, Prolapsed Grade II Internal Haemorrhoid, Prolapsed Grade III Internal Haemorrhoid
- Trial name
- NCT04398823
- Testing
- Sclerosing foam of Lauromacrogol, Sclersing liqiud of Lauromacrogol
- Where
- China
- Volunteers
- 700 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Hemorrhoids, Hemorrhoids, Internal
Comparison of Rubber Band Ligation and Haemorrhoidectomy in Patients With Symptomatic Haemorrhoids Grade III
Rationale: Haemorrhoidal disease is one of the most common anorectal disorders which affects nearly half of the general population1.
- Conditions
- Hemorrhoids, Hemorrhoids, Internal, PROM, Rectal Diseases
- Trial name
- HollAND (NCT04621695)
- Testing
- RBL, Hemorrhoidectomy
- Where
- 9 sites in Netherlands
- Volunteers
- 360 people
- Sponsor
- Proctos Kliniek
Hemorrhoids Second Degree, Traditional Chinese Medicine (TCM)
Traditional Medicine Syndromes in Internal Hemorrhoids: a Cross-Sectional Study
This study aims to investigate the characteristics of Traditional Medicine (TM) syndromes in patients diagnosed with internal hemorrhoids at Le Van Thinh Hospital.
- Trial name
- TMS-Hemorrhoid (NCT06876428)
- Volunteers
- 150 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Hemorrhoidal Bleeding, Hemorrhoids, Internal
Rectal Arterial Embolization vs Band Ligation for the Treatment of Internal hemOrrhoidS
The purpose of this clinical trial is to compare two standard of care non-surgical treatments for hemorrhoidal bleeding: hemorrhoidal artery embolization (HAE) versus rubber band ligation (RBL).
- Conditions
- Hemorrhoidal Bleeding, Hemorrhoids, Internal, HAE, RBL
- Trial name
- STRATOS (NCT07559630)
- Testing
- Hemorrhoidal Artery Embolization, Rubber Band Ligation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Jessica K. Stewart, MD
Haemorrhoids, Internal Haemorrhoids
Radiofrequency Ablation vs Doppler-guided Haemorrhoidal Artery Ligation in the Treatment of Haemorrhoidal Disease
Surgical treatment of grade II/III internal haemorrhoidal disease is indicated in the case of medical and/or instrumental treatment failure.
- Conditions
- Haemorrhoids, Internal Haemorrhoids, Grade II/III Haemorrhoids
- Trial name
- RADIOLIGA (NCT06170736)
- Testing
- Doppler-Guided Haemorrhoidal Artery Ligation, Radiofrequency ablation
- Where
- 18 sites in France
- Volunteers
- 168 people
- Sponsor
- Centre Hospitalier Departemental Vendee
Internal Hemorrhoid
Recurrence Rate of Minimally Invasive Endoscopic Treatment of Internal Hemorrhoids
2.1 Main objective: To observe the short-term and long-term recurrence rates of various endoscopic minimally invasive treatment methods for internal hemorrhoids and different time points of endoscopic minimally invasive treatment…
- Trial name
- NCT06250140
- Testing
- Tie up device
- Volunteers
- 900 people
- Sponsor
- Shenzhen Hospital of Southern Medical University
Internal Hemorrhoids
Evaluate Safety and Efficacy of 25 mg Hydrocortisone Acetate Suppositories in Treatment of Internal Hemorrhoids
A randomized, double-blind, placebo-controlled, multicenter, parallel group study of the safety and efficacy of Hydrocortisone Acetate Suppositories, 25 mg compared to placebo suppositories in the treatment of symptomatic…
- Trial name
- NCT03335774
- Testing
- Hydrocortisone Acetate Suppository, 25 mg (Nivagen)
- Where
- 2 sites in United States, India
- Volunteers
- 103 people
- Sponsor
- Nivagen Pharmaceuticals Inc.
Hemorrhoid
Laser Hemorrhoidoplasty Versus Open Hemorrhoidectomy for Postoperative Pain
Hemorrhoidal disease is a common condition that can cause symptoms such as rectal bleeding and protrusion of tissue through the anal canal.
- Trial name
- NCT07846904
- Testing
- Open Milligan-Morgan Hemorrhoidectomy, Laser Hemorrhoidoplasty
- Volunteers
- 68 people
- Sponsor
- Allied Hospital Faisalabad
Internal Hemorrhoids
Safety and Efficacy Study of Anucort HC TM 25mg Rectal Suppositories to Treat Symptomatic Internal Hemorrhoids
The primary objective of this study is to determine the safety and efficacy of G\&W Laboratories' Anucort HC TM (Hydrocortisone Acetate) 25mg Rectal Suppositories in subjects with internal hemorrhoidal symptoms.
- Trial name
- NCT01913158
- Testing
- Anucort-HC, 25 Mg Rectal Suppository
- Where
- 3 sites in United States
- Volunteers
- 150 people
- Sponsor
- G & W Laboratories Inc.
Haemorrhoids
The Relationship Between Haemorrhoids and Pelvic Vein Reflux
This case series aims to find out in a group of female patients suffering from haemorrhoids, how many of them have pelvic vein reflux that feeds into their haemorrhoids.
- Trial name
- NCT02039570
- Testing
- Transvaginal scan
- Where
- United Kingdom
- Volunteers
- 57 people
- Sponsor
- The Whiteley Clinic
Hemorrhoids Internal, Hemorrhoids Second Degree
Comparing Rectal Artery Embolization and Surgery for Treatment of Bleeding Grade 2 and 3 Internal Hemorrhoids
This Phase II study will compare rectal artery embolization with operative hemorrhoidectomy in adults with symptomatic bleeding grade 2 and 3 internal hemorrhoids.
- Conditions
- Hemorrhoids Internal, Hemorrhoids Second Degree, Hemorrhoids Third Degree
- Trial name
- HemEmbo (NCT07844629)
- Testing
- Rectal Artery Embolization, Operative Hemorrhoidectomy
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- University of Colorado, Denver
Lateral Internal Sphincterotomy, Hemorrhoidectomy
Hemorrhoidectomy With or Without Lateral Internal Sphincterotomy in Management of Patients With Hemorrhoids
This study aims to compare the lateral internal sphincterotomy versus no lateral internal sphincterotomy during hemorrhoidectomy in the management of patients with hemorrhoids.
- Conditions
- Lateral Internal Sphincterotomy, Hemorrhoidectomy, Hemorrhoids
- Trial name
- NCT06884774
- Testing
- Hemorrhoidectomy with lateral internal sphincterotomy, Hemorrhoidectomy
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Minia University
Hemorrhoids
Hemorrhoidectomy Only Versus Hemorrhoidectomy With Lateral Internal Sphincterotomy
The aim of this study was to access the comparison of pain and complications after hemorrhoidectomy with or without lateral sphincterotomy.
- Trial name
- NCT06588374
- Testing
- lateral internal sphincterotomy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Assiut University
Hemorrhoids, Internal
Safety and Efficacy Study of HET Bipolar System for Treatment of Stage I and Stage II Hemorrhoids
Hemorrhoids are vascular cushions in the anal canal. People are normally born with hemorrhoids, and the presence of hemorrhoids does not imply disease. However, hemorrhoids typically cause symptoms when they enlarge over time.
- Trial name
- NCT01841970
- Testing
- HET Bipolar System
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Medtronic - MITG
Hemorrhoid
The Efficacy of Aescin in Combination With Micronized Purified Flavonoid Fraction (MPFF) in the Control of Bleeding and Prevent Recurrence of Acute Internal Hemorrhoids, A Randomized Controlled Trial, A Pilot Study
Hemorrhoidal disease, characterized by symptomatic enlargement and distal displacement of anal cushions, has been a subject of recognition and management for centuries.
- Trial name
- NCT06748014
- Testing
- Aescin in Horse Chestnut, MPFF
- Where
- Thailand
- Volunteers
- 120 people
- Sponsor
- Chiang Mai University
Hemorrhoidal Disease, Internal Hemorrhoids
Clinical Outcomes After Laser Hemorrhoidoplasty
This single-center prospective observational study aims to evaluate clinical outcomes, postoperative pain scores, complications, and patient satisfaction in adults undergoing laser hemorrhoidoplasty for symptomatic internal…
- Trial name
- LHP (NCT07520734)
- Testing
- Laser Hemorrhoidoplasty
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sanliurfa Education and Research Hospital