Clinical trials: Internal Hemorrhoids
Hemorrhoid
The Efficacy of Aescin in Combination With Micronized Purified Flavonoid Fraction (MPFF) in the Control of Bleeding and Prevent Recurrence of Acute Internal Hemorrhoids, A Randomized Controlled Trial, A Pilot Study
Hemorrhoidal disease, characterized by symptomatic enlargement and distal displacement of anal cushions, has been a subject of recognition and management for centuries.
- Trial name
- NCT06748014
- Testing
- Aescin in Horse Chestnut, MPFF
- Where
- Thailand
- Volunteers
- 120 people
- Sponsor
- Chiang Mai University
Hemorrhoid, Hemorrhoids
Endoscopic Injection Sclerotherapy Versus Endoscopic Band Ligation for Grade I-III Internal Hemorrhoids
This study is a prospective, multicentre, and randomized-controlled clinical study.The researchers wanted to explore the optimal treatment regimen for soft hemorrhoid within I-Ⅲ degrees by evaluating and comparing the…
- Conditions
- Hemorrhoid, Hemorrhoids, Hemorrhoids Internal, Hemorrhoid Prolapse
- Trial name
- NCT05089500
- Testing
- Endoscopic injection sclerotherapy, Endoscopic Band Ligation
- Where
- 2 sites in China
- Volunteers
- 984 people, healthy volunteers welcome
- Sponsor
- Renmin Hospital of Wuhan University
Hemorrhoids
The Use of Topical Anaesthetic in the Banding of Internal Haemorrhoids
The investigators' aim is to assess if they can complete a study measuring the effect of local anaesthetic gel (Instillagel) on reducing pain experienced by patients undergoing a common treatment for haemorrhoids (piles).
- Trial name
- TAB (NCT04031131)
- Testing
- Instillagel, KY Gel
- Where
- United Kingdom
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Julie Dawson
Hemorrhoid, Cough
Cough and Hemorrhoids
The aim of the study is to investigate the relationship between hemorrhoids and cough by assessing the symptoms, duration, and severity of cough in patients who will present to the general surgery outpatient clinic of Muğla…
- Conditions
- Hemorrhoid, Cough, Cough Duration, Cough Frequency
- Trial name
- NCT06878209
- Where
- Turkey (Türkiye)
- Volunteers
- 134 people
- Sponsor
- Muğla Sıtkı Koçman University
Hemorrhoids
Long-term Efficacy of Doppler Ligation With Mucopexy in the Treatment of Internal Hemorrhoidal Disease
A classic distinction is made between internal and external hemorrhoidal pathology. External hemorrhoids can present with thrombosis, which causes painful swelling; internal hemorrhoids by rectal bleeding, prolapse, and more…
- Trial name
- HEM_THD (NCT04708678)
- Where
- France
- Volunteers
- 151 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Hemorrhoids Second Degree, Traditional Chinese Medicine (TCM)
Traditional Medicine Syndromes in Internal Hemorrhoids: a Cross-Sectional Study
This study aims to investigate the characteristics of Traditional Medicine (TM) syndromes in patients diagnosed with internal hemorrhoids at Le Van Thinh Hospital.
- Trial name
- TMS-Hemorrhoid (NCT06876428)
- Volunteers
- 150 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Grade III and IV Hemorrhoids
Haemorrhoidectomy With vs Without Lateral Internal Sphincterotomy
Hemorrhoids are a common anorectal condition that often require surgical treatment in advanced stages. Open hemorrhoidectomy is effective but is frequently associated with significant postoperative pain and early bleeding.
- Trial name
- NCT07360912
- Testing
- Hemorrhoidectomy With LIS, Conventional Hemorrhoidectomy
- Where
- Iraq
- Volunteers
- 120 people
- Sponsor
- University of Baghdad
Hemorrhoidal Bleeding, Hemorrhoids, Internal
Rectal Arterial Embolization vs Band Ligation for the Treatment of Internal hemOrrhoidS
The purpose of this clinical trial is to compare two standard of care non-surgical treatments for hemorrhoidal bleeding: hemorrhoidal artery embolization (HAE) versus rubber band ligation (RBL).
- Conditions
- Hemorrhoidal Bleeding, Hemorrhoids, Internal, HAE, RBL
- Trial name
- STRATOS (NCT07559630)
- Testing
- Hemorrhoidal Artery Embolization, Rubber Band Ligation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Jessica K. Stewart, MD
Internal Hemorrhoids
Study About Patient Comfort and Long-term Outcome After Stapled Hemorrhoidopexy
The purpose of this study was to determine the influence on Patient comfort after Stapled Hemorrhoidopexy versus Milligan Morgan (two surgical procedures)in third degree circular hemorrhoids.
- Trial name
- NCT01533363
- Testing
- Stapled hemorrhoidopexy, Milligan Morgan
- Volunteers
- 130 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Internal Hemorrhoid, Rectal Prolapse
Cap-assisted Endoscopic Sclerotherapy for Internal Hemorrhoids and Rectal Prolapse
This clinical trial aims to evaluate the efficacy and safety of long needle and short needle in the treatment of internal hemorrhoids and rectal prolapse through CAES (Cap-assisted endoscopic sclerotherapy).
- Trial name
- NCT03917056
- Testing
- Cap-assisted endoscopic sclerotherapy using long needle, Cap-assisted endoscopic sclerotherapy using short needle
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- The Second Hospital of Nanjing Medical University
Liver Cirrhosis, Internal Hemorrhoid
A Comparison of Flexible Endoscopic Polidocanol Liquid and Foam Sclerotherapy in Cirrhotic Patients With Bleeding From Internal Hemorrhoids
Haemorrhoids are the most common proctologic disease, affecting up to 36% of people in the developed world. Sclerotherapy is defined as the injection of sclerosing agents at the apex of the internal hemorrhoidal complex, above the…
- Trial name
- NCT06031740
- Testing
- Sclerotherapy with 1.5% polidocanol, Foam sclerotherapy.
- Where
- India
- Volunteers
- 60 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Internal Hemorrhoids, Postoperative Pain After Endoscopic Rubber Band Ligation
Nitroglycerin Ointment for Pain Relief After Endoscopic Hemorrhoid Band Ligation
This study is designed to evaluate whether nitroglycerin ointment can reduce pain after endoscopic rubber band ligation for internal hemorrhoids.
- Trial name
- NCT07391501
- Testing
- Nitroglycerin Ointment
- Volunteers
- 68 people
- Sponsor
- Ying Zhu
Hemorrhoids
Hemorrhoidectomy Only Versus Hemorrhoidectomy With Lateral Internal Sphincterotomy
The aim of this study was to access the comparison of pain and complications after hemorrhoidectomy with or without lateral sphincterotomy.
- Trial name
- NCT06588374
- Testing
- lateral internal sphincterotomy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Assiut University
Anorectal Disorder
The Efficacy of Aescin in Combination With MPFF in the Early Control of Bleeding From Acute Internal Hemorrhoids, A Randomized Controlled Trial
Hemorrhoidal disease, characterized by symptomatic enlargement and distal displacement of anal cushions, has been a subject of recognition and management for centuries.
- Trial name
- NCT06363513
- Testing
- Aescin in Horse Chestnut, Flavonoid
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Chiang Mai University
Hemorrhoids Third Degree, Internal Hemorrhoids
HELO Trial: Energy-Based Therapies vs. Conventional Hemorrhoidectomy for Grade III Hemorrhoids
This prospective, multicenter study compares the efficacy and functional outcomes of three surgical treatments for symptomatic Goligher Grade III internal hemorrhoids: Laser Hemorrhoidoplasty (LHP), Hemorrhoid Energy Therapy…
- Conditions
- Hemorrhoids Third Degree, Internal Hemorrhoids, Mixed Hemorrhoids
- Trial name
- HELO (NCT07333040)
- Testing
- Laser Hemorrhoidoplasty (LHP), Hemorrhoid Energy Therapy (HET), Ferguson Hemorrhoidectomy
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Chang Gung Memorial Hospital
Hemorrhoids, Internal
Polidocanol Foam Versus Rubber Band Ligation in the Treatment of Hemorrhoidal Disease
Background: Hemorrhoidal disease is a common benign condition seen frequently in clinical settings. Rubber band ligation and sclerotherapy have proven to be the office-based procedures of choice in hemorrhoidal disease, with…
- Trial name
- NCT04091763
- Testing
- Polidocanol Injectable Foam, Rubber band ligation
- Where
- Portugal
- Volunteers
- 120 people
- Sponsor
- Universidade do Porto
Hemorrhoids
Comparison Between Two Endoscopic Treatments of Bleeding Internal Hemorrhoids:Band Ligation and Electrocoagulation Probe
The purpose of this study is to determine which treatment, band ligation (placing rubber bands around the hemorrhoids) or BICAP electrocoagulation (using electricity to cauterize) is safer and more effective endoscopic treatment…
- Trial name
- NCT00630669
- Testing
- Rubber band ligation, Bipolar coagulation
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of California, Los Angeles
Grade/Stage I Hemorrhoids, Prolapsed Grade II Internal Haemorrhoid
A Multicenter Prospective Clinical Study of Endoscopic Foam Sclerotherapy for Internal Hemorrhoids
"Internal hemorrhoid" affects the quality of life due to hemorrhage and prolapse as a common and frequently-occurring disease. Endoscopic sclerosing agent injection has replaced traditional surgery and become the most commonly…
- Conditions
- Grade/Stage I Hemorrhoids, Prolapsed Grade II Internal Haemorrhoid, Prolapsed Grade III Internal Haemorrhoid
- Trial name
- NCT04398823
- Testing
- Sclerosing foam of Lauromacrogol, Sclersing liqiud of Lauromacrogol
- Where
- China
- Volunteers
- 700 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Internal Piles Sclerotherapy, Internal Hemorrhoids
Evaluation of Polidocanol Foam Sclerotherapy in Symptomatic Internal Hemorrhoids: A Prospective Study
To evaluate the efficacy, durability, safety, and clinical/endoscopic outcomes of standardized 3% polidocanol foam sclerotherapy in patients with symptomatic grade II-III internal hemorrhoids over a 12-month follow-up period.
- Trial name
- NCT07866248
- Testing
- Standardized 3% Polidocanol Foam Sclerotherapy
- Volunteers
- 130 people
- Sponsor
- Radwa Hussein Mohammed Hasanen
Hemorrhoids, Hemorrhoids, Internal
SCI-Pex Study - Safety and Performance of PexyEazy®, a Device for Treatment of Hemorrhoids
The SCI-Pex study is a multicenter, prospective, non-controlled investigation on PexyEazy®, a new device for treatment of hemorrhoids based on the mucopexy method.
- Conditions
- Hemorrhoids, Hemorrhoids, Internal, Suture; Complications, Infection or Inflammation, Rectal Diseases
- Trial name
- SCI-Pex (NCT05782010)
- Testing
- PexyEazy
- Where
- 3 sites in Sweden
- Volunteers
- 35 people
- Sponsor
- Developeration AB