Clinical trials: Internuclear Ophthalmoplegia
Multiple Sclerosis, Internuclear Ophthalmoplegia
Clemastine Fumarate as Remyelinating Treatment in Internuclear Ophthalmoparesis and Multiple Sclerosis
Rationale: Clemastine fumarate has been identified as potential remyelinating therapy for multiple sclerosis (MS). The (long-term) effects of clemastine need to be confirmed in clinical models for MS.
- Trial name
- RESTORE (NCT05338450)
- Testing
- Clemastine Fumarate
- Where
- Netherlands
- Volunteers
- 47 people
- Sponsor
- Amsterdam UMC, location VUmc
Multiple Sclerosis, Internuclear Ophthalmoplegia
Studying Eye Movement Deficits and Cognitive Impairment in Patients with Multiple Sclerosis Using Infrared Eye Tracking and Cognitive Tests
The goal of this observational study is to study the relationship between cognitive problems and problems in eye movements in Multiple Sclerosis (MS).
- Trial name
- VisuMS (NCT06629155)
- Testing
- Infrared oculography
- Volunteers
- 50 people
- Sponsor
- Universitair Ziekenhuis Brussel
Multiple Sclerosis, Internuclear Ophthalmoplegia
Internuclear Ophthalmoplegia and Multiple Sclerosis: a Multicenter Retrospective Study
Internuclear ophthalmoplegia is a symptom frequently associated with multiple sclerosis (MS), although other etiologies are possible.
- Trial name
- INO&MS (NCT07560995)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Strasbourg, France
Multiple Sclerosis, Internuclear Ophthalmoplegia
Study and Treatment of Visual Dysfunction and Motor Fatigue in Multiple Sclerosis
Primary fatigue represents a major cause of disability in patients with multiple sclerosis (MS), being reported in about 90% of cases.
- Conditions
- Multiple Sclerosis, Internuclear Ophthalmoplegia, Fatigue
- Trial name
- NCT02391961
- Testing
- Dalfampridine
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- VA Office of Research and Development
Internuclear Ophthalmoplegia, Palsy, Abducens
Head-Cancelled Virtual Reality for Ocular Cranial Nerve Palsies
This study is investigating whether eye exercises for abducens palsy and internuclear ophthalmoplegia increase ocular range of motion in the paretic direction when performed in virtual reality under head-cancelled compared to…
- Trial name
- OCNP (NCT06417216)
- Testing
- Head-cancelled virtual reality
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kevin Houston