Clinical trials: Interstitial Cystitis/Bladder Pain Syndrome
Painful Bladder Syndrome (PBS), Interstitial Cystitis
Submucosal Intravesical Injection of Platelet-rich Plasma in the Treatment of Painful Bladder Syndrome
Interstitial cystitis/painful bladder syndrome (IC/PBS) is characterized by a constellation of bladder symptoms, including urinary frequency, urgency, nocturia, and pelvic pain.
- Trial name
- PRP (NCT06209008)
- Testing
- Intravesical injection of Platlet Rich Plasma (PRP)
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Interstitial Cystitis, Painful Bladder Syndrome
Physical Therapy Trial for Pelvic Pain
The purpose of this study is to determine if a randomized trial of physical therapy for pelvic pain is feasible.
- Conditions
- Interstitial Cystitis, Painful Bladder Syndrome, Chronic Prostatitis, Chronic Pelvic Pain Syndrome
- Trial name
- UPPCRN-RCT#1 (NCT00434343)
- Testing
- Global Therapeutic Massage (GTM), Myofascial physical therapy (MPT)
- Where
- 5 sites in United States
- Volunteers
- 47 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Bladder Pain Syndrome
GAG-therapy Efficacy Trial Solution for Bladder Pain Syndrome/ Interstitial Cystitis (GETSBI Study)
Rationale: Efficacy study (RCT) for glycosaminoglycan(GAG)-therapy for the indication bladder pain syndrome / interstitial cystitis with Hunner lesion subtype (BPS-IC H+).
- Trial name
- GETSBI (NCT05518864)
- Testing
- IALURIL Prefill
- Where
- 8 sites in Netherlands
- Volunteers
- 80 people
- Sponsor
- Radboud University Medical Center
Interstitial Cystitis, Levator Spasm
A Multidisciplinary, Multimodal Bundled Care Approach to Chronic Pelvic Pain
The goal of this clinical trial is to compare two different treatment patterns in patients with chronic bladder pain. The main questions the investigators are seeking to answer is if bladder pain improves before and after…
- Conditions
- Interstitial Cystitis, Levator Spasm, Bladder Pain Syndrome
- Trial name
- NCT05658874
- Testing
- Multimodal Bundle Drugs, Operative Cystoscopy, Behavioral health consultation/therapy
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Jocelyn Fitzgerald
Overactive Bladder, Bladder Pain Syndrome
Bladder Botox UTI Antibiotic Prophylaxis
Overactive bladder (OAB) is a common condition with a prevalence of 17% in the general population that significantly affects quality of life.
- Trial name
- NCT06387329
- Testing
- Nitrofurantoin 100 MG
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Walter Reed National Military Medical Center
Interstitial Cystitis, Recurrent Cystitis
Evaluating the Efficacy and Patient Experience of Catheter-Free Intravesical Instillation
This study aims to evaluate a catheter-free method for delivering medications directly into the bladder, known as intravesical instillation, which is commonly used to treat conditions such as interstitial cystitis/bladder pain…
- Conditions
- Interstitial Cystitis, Recurrent Cystitis, Haemorrhagic Cystitis, Bladder Cancer
- Trial name
- NOCATIN (NCT06719232)
- Testing
- Catheter-Free Intravesical Instillation with a special syringe adapter
- Where
- 2 sites in Hungary
- Volunteers
- 300 people
- Sponsor
- Jahn Ferenc South Pest Teaching Hospital
Interstitial Cystitis, Painful Bladder Syndrome
Bladder Capacity as Objective Measure of Intravesical Treatment of Newly Diagnosed IC
A comparative study of subjective outcomes following intravesical treatment of interstitial cystitis (IC) is lacking in the literature.
- Trial name
- NCT05223244
- Testing
- bupivacaine, triamcinolone, and heparin (BTH), dimethyl sulfoxide (DMSO)
- Volunteers
- 83 people
- Sponsor
- Endeavor Health
Bladder Pain Syndrome, Interstitial Cystitis
Acupuncture First for IC/BPS
The goal of this clinical trial is to learn if acupuncture in addition to behavioral changes can better treat in women with bladder pain syndrome (also known as interstitial cystitis) that have not received other treatments.
- Trial name
- NCT06366269
- Testing
- Acupuncture, Behavioral management, Physical therapy
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University Hospitals Cleveland Medical Center
Interstitial Cystitis, Bladder Pain Syndrome
Intravesical Ozone Therapy for Interstitial Cystitis/Bladder Pain Syndrome
This randomized, double-blind, placebo-controlled trial evaluated the efficacy and safety of intravesical ozone therapy in 60 patients with interstitial cystitis (IC).
- Trial name
- NCT06863220
- Testing
- Intravesical Ozone Therapy, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Interstitial Cystitis, Bladder Pain Syndrome
Biopsychosocial and Conventional Approach in Bladder Pain Syndrome
The aim of the present study is to compare the effects of biopsychosocial and conventional approach on symptom severity, pain parameters (pain intensity and pain cognitions), disability, psychological distress and quality of life…
- Trial name
- NCT05155384
- Testing
- Pain Neuroscience Education, Relaxation exercises, Cognition target exercise
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Hacettepe University
Bladder Pain Syndrome, Educational Behavioral Intervention
Mirogabalin Plus EBMP for IC/BPS
The goal of this clinical trial is to learn whether adding mirogabalin to educational-behavioral modification program (EBMP) improves symptoms and safety outcomes for adults living with interstitial cystitis/bladder pain syndrome…
- Conditions
- Bladder Pain Syndrome, Educational Behavioral Intervention, Urinary Urgency
- Trial name
- M-EBMP-IC/BPS (NCT07803393)
- Testing
- Behavioral: Educational and Behavioral Management Program (EBMP), Intervention
- Volunteers
- 200 people
- Sponsor
- Beijing Tiantan Hospital
Chronic Pain, Acute Pain
Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA
This study relies on the use of a smartphone application (SOMA) that the investigators developed for tracking daily mood, pain, and activity status in acute pain, chronic pain, and healthy controls over four months.The primary…
- Conditions
- Chronic Pain, Acute Pain, Post Operative Pain, Fibromyalgia, Primary
- Trial name
- NCT05754190
- Testing
- SOMA pain manager smartphone application
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Brown University
Interstitial Cystitis and Bladder Pain Syndrome
Learning to THRIVE (L2T) Program Pilot
This pilot study evaluated the feasibility and potential effects of Learning to THRIVE (L2T), a six-week online educational self-management program for adults who self-identified as women or female and had interstitial…
- Trial name
- L2T (NCT07797010)
- Testing
- Learning to THRIVE (L2T) Program
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Indianapolis
Painful Bladder Syndrome
A Pilot Study Investigating the Use of a Therapeutic Wand in Addition to Physiotherapy for Bladder Pain Syndrome
Bladder pain syndrome is a condition where pain is experienced when the bladder fills with urine and eases briefly when the bladder empties. There can also be a constant need to urgently empty the bladder.
- Trial name
- NCT02743962
- Testing
- Therapeutic Wand, Routine physiotherapy control
- Volunteers
- 10 people
- Sponsor
- University of Bradford
Interstitial Cystitis/Painful Bladder Syndrome, Myofascial Pelvic Pain
Interstitial Cystitis: Elucidation of the Psychophysiologic and Autonomic Characteristics (ICEPAC) Study
Interstitial cystitis/painful bladder syndrome (IC/PBS) causes severe bladder pain and extensive disability in a large group of women int he prime of their productive lives.
- Trial name
- ICEPAC (NCT01616992)
- Testing
- Bupivacaine
- Where
- 2 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Painful Bladder Syndrome, Interstitial Cystitis
Clinical Efficacy of Changing the InterStim® Parameters in Patients With Interstitial Cystitis/Painful Bladder Syndrome
Purpose: 1. To demonstrate better symptoms control (pain, urinary urgency and frequency) with sacral neuromodulation (SNM) in patients with interstitial cystitis /painful bladder syndrome (IC/PBS) using a stimulation frequency of…
- Conditions
- Painful Bladder Syndrome, Interstitial Cystitis, Pelvic Floor; Insufficiency, Bowel Dysfunction
- Trial name
- NCT01312259
- Testing
- Changing the Interstim parameter of '' Frequency" in patients with Interstitial Cystitis
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Pelvic and Sexual Health Institute
IC, Hunner Type Interstitial Cystitis
The Study is Being Conducted to Find a New Treatment for Patients Suffering From Interstitial Cystitis With Hunner's Lesions
To evaluate the efficacy and safety of Neovasculgen in interstitial cystitis with Hunner's lesions to reduce cicatricial changes in the bladder caused by electrocoagulation and to prevent secondary bladder shrinkage with a…
- Conditions
- IC, Hunner Type Interstitial Cystitis, Bladder Pain Syndrome
- Trial name
- NCT07459790
- Testing
- Neovasculgen®
- Where
- Russia
- Volunteers
- 180 people
- Sponsor
- JSC NextGen
Fibromyalgia, Irritable Bowel Syndrome
Observational Study of Control Participants for the MAPP Research Network
The Control Study for the Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network has been established to focus on a broader approach to the study of Interstitial Cystitis (IC)/Painful Bladder…
- Conditions
- Fibromyalgia, Irritable Bowel Syndrome, Fatigue Syndrome, Chronic
- Trial name
- MAPP-Control (NCT01098292)
- Where
- 8 sites in United States
- Volunteers
- 615 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Interstitial Cystitis
The Efficacy and Safety of Intravesical Hyaluronic Acid and Chondroitin Sulfate After Transurethral Resection of Hunner Lesion in Interstitial Cystitis/Bladder Pain Syndrome Patients
The efficacy and safety of intravesical hyaluronic acid and chondroitin sulfate after transurethral resection of Hunner lesion in interstitial cystitis/bladder pain syndrome patients.
- Trial name
- NCT03463499
- Testing
- Hyaluronic Acid and Chondroitin Sulfate
- Where
- South Korea
- Volunteers
- 62 people
- Sponsor
- Samsung Medical Center
Interstitial Cystitis
Safety Study of Single Intravesical Doses of TTI-1612 in Women With Interstitial Cystitis/Bladder Pain Syndrome
The purpose of this study is to determine the safety and pharmacokinetics of TTI-1612 in women with interstitial cystitis/bladder pain syndrome.
- Trial name
- NCT01559961
- Testing
- TTI-1612
- Where
- 4 sites in Canada
- Volunteers
- 28 people
- Sponsor
- Trillium Therapeutics Inc.