Clinical trials: Interstitial Cystitis/Painful Bladder Syndrome
Interstitial Cystitis, Stem Cell Transplant
Safety of Human Embryonic Stem Cell (hESC)-Derived Mesenchymal Stem Cells in Interstitial Cystitis
This study primarily aimed to evaluate the safety of human embryonic stem cell (hESC)-derived mesenchyma stem cells in interstitial cystitis.
- Conditions
- Interstitial Cystitis, Stem Cell Transplant, Mesenchymal Stem Cell
- Trial name
- NCT04610359
- Testing
- MR-MC-01
- Where
- South Korea
- Volunteers
- 3 people
- Sponsor
- Asan Medical Center
Interstitial Cystitis, Painful Bladder Syndrome
Amniotic Membrane Therapy for Interstitial Cystitis/Painful Bladder Syndrome
Interstitial cystitis/painful bladder syndrome (IC/PBS) is a clinical syndrome in which patients report symptoms of bladder and/or pelvic pain with pressure and/ or discomfort associated with urinary frequency and urgency.
- Conditions
- Interstitial Cystitis, Painful Bladder Syndrome, Painful Bladder Syndrome (PBS)
- Trial name
- NCT06096597
- Testing
- Clarix Flo
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- David Sheyn
Cystitis, Interstitial
Smartphone-based Self-care Education Program for Women With Interstitial Cystitis: Educational Remote IC Aide
To implement and assess clinical efficacy of a text message and multimedia-based program that (i) remotely delivers first- and second-line American Urological Association (AUA) treatments of IC/BPS; (ii) integrates treatment of…
- Trial name
- ERICA (NCT05260112)
- Testing
- ERICA
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Pennsylvania
Interstitial Cystitis, Bladder Pain Syndrome
Intradetrusor Triamcinolone Injection in the Management of Interstitial Cystitis/Bladder Pain Syndrome
This initial pilot project aims to study the use of FDA-approved 40mg triamcinolone injections in the bladder for the management of interstitial cystitis with or without Hunner's lesions.
- Trial name
- NCT05226832
- Testing
- 40mg Triamcinolone Injections in the Bladder
- Sponsor
- The University of Texas Medical Branch, Galveston
Interstitial Cystitis
Effectiveness and Safety Study of Pentosan Polysulfate Sodium for the Treatment of Interstitial Cystitis
The purpose of this study is to evaluate the safety and effectiveness of pentosan polysulfate sodium 100 mg once a day, pentosan polysulfate sodium 100 mg three times a day, and placebo for 24 weeks for the relief of bladder pain…
- Trial name
- NCT00086684
- Testing
- Pentosan polysulfate sodium 100 mg
- Where
- 65 sites in United States, Canada
- Volunteers
- 369 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Bladder Pain Syndrome, Female Sexual Dysfunction
Effect of Intradetrusor onabotulinumtoxinA Injection Versus Conservative Management on Female Sexual Function in Patients With Bladder Pain Syndrome
Interstitial cystitis/bladder pain syndrome (IC/BPS) is estimated to affect 3.3 to 7.9 million women aged 18 years and older in the United States.
- Trial name
- NCT06729151
- Testing
- Onabotulinum toxin A, Conservative management (dietary and behavioral)
- Where
- United States
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Walter Reed National Military Medical Center
Urologic Chronic Pelvic Pain Syndrome (UCPPS), Interstitial Cystitis
EPPIC: Easing Pelvic Pain Interventions Clinical Research Program
The EPPIC (Easing Pelvic Pain Interventions Clinical Research Program) study evaluates an ultra-brief, 4 session cognitive behavioral pain treatment transdiagnostic in design for urologic chronic pain syndrome (UCPPS) with…
- Conditions
- Urologic Chronic Pelvic Pain Syndrome (UCPPS), Interstitial Cystitis, Bladder Pain Syndrome, Chronic Prostatitis
- Trial name
- EPPIC (NCT05127616)
- Testing
- Minimal Contact-Cognitive Behavior Therapy, Patient Education/Support
- Where
- 3 sites in United States
- Volunteers
- 240 people
- Sponsor
- State University of New York at Buffalo
Interstitial Cystitis
Interstitial Cystitis (IC)-Like Findings With Hydrodistension
Patients who are already scheduled to have a gynecologic, urologic or uro-gynecologic procedure involving cystoscopy (a lighted scope is used to look inside the bladder) under anesthesia will be approached to participate in the…
- Trial name
- NCT02547298
- Where
- United States
- Volunteers
- 734 people
- Sponsor
- St. Louis University
Overactive Bladder, Bladder Pain Syndrome
Bladder Botox UTI Antibiotic Prophylaxis
Overactive bladder (OAB) is a common condition with a prevalence of 17% in the general population that significantly affects quality of life.
- Trial name
- NCT06387329
- Testing
- Nitrofurantoin 100 MG
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Walter Reed National Military Medical Center
Painful Bladder Syndrome, Interstitial Cystitis
URACYST® For the Treatment of GAG Deficient Interstitial Cystitis
This protocol describes a multi-centre, community based open label study designed to assess the efficacy and safety of intravesical sodium chrondroitin sulfate (Uracyst®) in the treatment of patients with a clinical diagnosis of…
- Trial name
- NCT00150488
- Testing
- Uracyst
- Where
- Canada
- Volunteers
- 53 people
- Sponsor
- Dr. J. Curtis Nickel
Interstitial Cystitis
The Efficacy of Biomarker in Patient With Interstitial Cystitis/Painful Bladder Syndrome
The purpose of this study is to evaluate efficacy of biomarker in patient with interstitial cystitis/painful bladder syndrome
- Trial name
- NCT01985880
- Where
- 2 sites in South Korea
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Cystitis, Interstitial
Study Evaluating Orally Administered ERB-041 in Subjects With Active Interstitial Cystitis
This is a multicenter, randomized, double-blind, placebo-controlled, parallel-design, exploratory study of orally administered ERB-041 in subjects with active IC.
- Trial name
- NCT00275379
- Testing
- ERB-041
- Where
- 16 sites in United States, Austria and 1 more
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Chronic Pelvic Pain, Interstitial Cystitis
Effect of Repetitive Transcranial Direct Current Stimulation (tDCS) on Chronic Pelvic Pain
We will rigorously test whether modulation of the motor cortex by transcranial direct current stimulation (tDCS) is an effective treatment for patients with chronic pelvic pain through the following specific aims: A) The primary…
- Conditions
- Chronic Pelvic Pain, Interstitial Cystitis, Post Traumatic Stress Disorder, Fibromyalgia
- Trial name
- NCT00554320
- Testing
- tDCS
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Summa Health System
Chronic Interstitial Cystitis, Bladder Pain Syndrome
Optimizing Psychosocial Treatment of Interstitial Cystitis/Bladder Pain Syndrome
Interstitial cystitis/bladder pain syndrome (IC/BPS) is a severe pain condition affecting 3-8 million people in the United States lacking treatments that work.
- Conditions
- Chronic Interstitial Cystitis, Bladder Pain Syndrome, Cystitis, Interstitial, Painful Bladder Syndrome
- Trial name
- NCT04275297
- Testing
- Psychosocial Treatment, Attention Control
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Vanderbilt University Medical Center
Interstitial Cystitis
The Efficacy of Additional Intravesical Instillation of Hyaluronic Acid/Chondroitin Sulfate to Transurethral Resection of Bladder Ulcer in Patients With Interstitial Cystitis/Bladder Pain Syndrome.
The purpose of this study is to evaluate efficacy and safety of additional hyaluronic acid/chondroitin sulfate to transurethral resection of bladder ulcer in patient with interstitial cystitis.
- Trial name
- NCT01813565
- Testing
- Hyaluronic acid/chondroitin sulfate
- Where
- South Korea
- Volunteers
- 15 people
- Sponsor
- Asan Medical Center
Interstitial Cystitis, Irritable Bowel Syndrome
MAPP Investigation of Pelvic Floor-Brain Neurobiologic Axis in IC/IBS and IBS
Hypotheses: 1. The bidirectional signaling between the cortex, and the pelvic floor/gut is deranged in patients with IC and in IBS.
- Trial name
- NCT01280864
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Augusta University
Interstitial Cystitis
Double-Blind Placebo Controlled Study of Safety,Tolerability, and Efficacy of LiRIS® in Women With Interstitial Cystitis
The purpose of this study is to determine if LiRIS®, an investigational drug-delivery system, is safe, tolerable and effective in women with Interstitial Cystitis.
- Trial name
- NCT01475253
- Testing
- Lidocaine Releasing Intravesical System - LiRIS®
- Where
- 29 sites in United States, Canada
- Volunteers
- 104 people
- Sponsor
- Allergan
Interstitial Cystitis, Chronic, Bladder Pain Syndrome
Evaluation of Response to Use of Intravesical Ozone Gas in Interstitial Cystitis /Bladder Pain Syndrome
Interstitial Cystitis / bladder pain syndrome (CI / BPS) is a debilitating pathology with a negative impact on the quality of life of affected individuals.
- Trial name
- NCT04789135
- Testing
- Ozone
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Anhembi Morumbi University
Interstitial Cystitis, Chronic
RADIOFREQUENCY TREATMENT OF CHRONIC PELVIC PAIN MANAGEMENT IN INTERSTITIAL CYSTITIS
Interstitial cystitis/painful bladder syndrome is a collection of symptoms that includes urinary urgency, urge incontinence, nocturia, and painful urination.
- Trial name
- NCT06256679
- Testing
- superior hypogastric plexus pulsed radiofrequency and transcutaneous tibial nerve stimulation, superior hypogastric plexus pulsed radiofrequency
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Turkish League Against Rheumatism
Interstitial Cystitis, Painful Bladder Syndrome
Bladder Thermal Distention for Patients With Interstitial Cystitis / Painful Bladder Syndrome
Patients with Interstitial Cystitis / PBS will be treated with bladder thermal distention (BTD).
- Trial name
- IC (NCT01838486)
- Testing
- Bladder Thermal Distention
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Assaf-Harofeh Medical Center