Clinical trials: Interstitial Cystitis/Painful Bladder Syndrome
Painful Bladder Syndrome, Interstitial Cystitis
Botox as a Treatment for Interstitial Cystitis in Women
Patients with interstitial cystitis have been well documented to have pelvic floor muscle tenderness as well as pain on bladder distension.
- Trial name
- NCT00194610
- Testing
- Botox, normal saline
- Volunteers
- 20 people
- Sponsor
- University of Washington
Safety and Effectiveness Between Intravesical Platelet-rich Plasma Injection in Patients With Interstitial Cystitis/Bladder
Intravesical Platelet-rich Plasma Injection in Patients With Interstitial Cystitis/Bladder-A Retrospective Study
The correlation of safety and effectiveness between intravesical platelet-rich plasma injection in patients with interstitial cystitis/bladder-A retrospective study to evaluate the correlation of safety and effectiveness between…
- Trial name
- NCT06339645
- Testing
- PRP
- Where
- Taiwan
- Volunteers
- 658 people
- Sponsor
- Hualien Tzu Chi General Hospital
Overactive Bladder, Stress Incontinence
Effects of Low-intensity Excoporeal Shock Wave Therapy (LiESWT) on Women With Pelvic Floor Dysfunction
1. This study needles female reproductive urinary tract, likely bladder hyperactivity, active urinary incontinence and interstitial cystitis, observation use of low-capacity seismic wave (LiESWT) therapy combined with combined…
- Conditions
- Overactive Bladder, Stress Incontinence, Interstitial Cystitis, Female Sexual Dysfunction
- Trial name
- NCT05337813
- Testing
- "Storz Medical" Extracoporeeal Shock Wave Therapy System
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Interstitial Cystitis, Bladder Pain Syndrome
Safety and Efficacy Study of VNX001 Compared to Its Individual Components (Lidocaine and Heparin) or Placebo in Subjects With IC/BPS
This is a Phase 2, prospective, randomized, double-blind, placebo-controlled, multi-center, single-dose, pharmacodynamic study designed to evaluate the efficacy and safety of the combination product (VNX001) versus placebo and…
- Trial name
- NCT05737121
- Testing
- VNX001, Lidocaine, Heparin
- Where
- 14 sites in United States
- Volunteers
- 120 people
- Sponsor
- Vaneltix Pharma, Inc.
Cystitis, Interstitial
An Effectiveness and Safety Study of PF-04383119 for the Treatment of Pain in Interstitial Cystitis
The purpose of this study is to determine whether PF-04383119 is effective in the treatment of pain associated with interstitial cystitis.
- Trial name
- NCT00601484
- Testing
- PF-04383119
- Where
- 34 sites in United States
- Volunteers
- 65 people
- Sponsor
- Pfizer
Overactive Bladder, Urinary Urge Incontinence
Reduction of Bladder Injection Pain With Belladonna Opiate Suppository
The purpose of this study is to test whether using belladonna \& opiate suppositories (B\&Os) can improve patient discomfort during Onabotulinumtoxin A (BoNT) injection into the bladder for treatment of overactive bladder…
- Conditions
- Overactive Bladder, Urinary Urge Incontinence, Urinary Bladder, Neurogenic, Painful Bladder Syndrome
- Trial name
- ROBIN (NCT02600715)
- Testing
- Onabotulinumtoxin A (BoNT), belladonna, Morphine
- Where
- 2 sites in United States
- Volunteers
- 26 people
- Sponsor
- Edgar LeClaire, MD
Interstitial Cystitis
Safety Study of Single Intravesical Doses of TTI-1612 in Women With Interstitial Cystitis/Bladder Pain Syndrome
The purpose of this study is to determine the safety and pharmacokinetics of TTI-1612 in women with interstitial cystitis/bladder pain syndrome.
- Trial name
- NCT01559961
- Testing
- TTI-1612
- Where
- 4 sites in Canada
- Volunteers
- 28 people
- Sponsor
- Trillium Therapeutics Inc.
Bladder Pain Syndrome
Comparative Study Suburothelial and Trigonal Botulinum Toxin A Injection in Treatment of Interstitial Cystitis
There is no consensus of the therapeutic efficacy and safety between suburothelial injection and trigonal injection of botulinum toxin A (BoNT-A) in treatment of interstitial cystitis/bladder pain syndrome (IC/BPS) It is unmet to…
- Trial name
- NCT03076762
- Testing
- intravesical onabotulinumtoxinA injection
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Buddhist Tzu Chi General Hospital
Interstitial Cystitis, Chronic Interstitial Cystitis
Investigation of PEMF Therapy for Female Patients With IC/BPS
The purpose of this study is to gather information about the safety and effectiveness of the non-pharmacological (non-drug), non-invasive treatment known as low-frequency pulsed electromagnetic field (PEMF) therapy.
- Conditions
- Interstitial Cystitis, Chronic Interstitial Cystitis, Bladder Pain Syndrome
- Trial name
- NCT05149573
- Testing
- Pulsed Electromagnetic Field (PEMF) Device
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Wake Forest University Health Sciences
Interstitial Cystitis, Painful Bladder Syndrome
Physiotherapeutic Interventions Applied to the Bladder Pain Syndrome
Related to urological and gynecological systems, patients with Bladdeer Pain Syndrome (BPS) often present pain, pressure and chronic discomfort in suprapubic and perineal area associated with low urinary tract symptoms.
- Conditions
- Interstitial Cystitis, Painful Bladder Syndrome, Bladder Pain Syndrome
- Trial name
- NCT03755375
- Testing
- TENS, Postural exercises, Biofeedback
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- University of Sao Paulo General Hospital
Interstitial Cystitis, Bladder Pain Syndrome
The CBD-IC Randomized Controlled Trial: Evaluation of Hemp Cannabidiol SuppositoRies for Pain and Urinary SymptOms in INterstitial Cystitis (CHRONIC)
This study seeks to exploit bladder cannabidiol receptors as a therapeutic drug target by conducting a double-masked, placebo-controlled randomized trial evaluating the effects of vaginal hemp cannabidiol (CBD) suppositories on…
- Trial name
- CHRONIC (NCT04349930)
- Testing
- Cannabidiol vaginal suppository
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of New Mexico
Fibromyalgia, Interstitial Cystitis
HBOT for Patients With IC/FM (Interstitial Cystitis/Fibromyalgia)
The investigators observed 12 fibromyalgia and interstitial cystitis patients undergoing hyperbaric oxygen oxygen treatment in a multiplace pressure chamber for 90 minutes, 40 treatment each, using an oro-nasal mask.
- Trial name
- IC/FMHBOT (NCT03693001)
- Testing
- Intermittent Exposure to Oxygen via Oro-Nasal Mask
- Volunteers
- 12 people
- Sponsor
- University of South Florida
Interstitial Cystitis, Chronic Prostatitis
Microbiomes of Pelvic Pain
This research study seeks to provide more insight as to how the microbiome affects or is affected by conditions causing chronic pelvic pain such as Interstitial Cystitis (IC), Chronic Prostatitis/Chronic Pelvic Pain Syndrome…
- Conditions
- Interstitial Cystitis, Chronic Prostatitis, Chronic Pelvic Pain Syndrome, Lower Urinary Tract Symptoms
- Trial name
- NCT01738464
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Chronic Interstitial Cystitis, Bladder Pain Syndrome
Pain Type and Interstitial Cystitis/Bladder Pain Syndrome Treatment
Interstitial cystitis/bladder pain syndrome (IC/BPS) is a severe pain condition affecting 3-8 million people in the United States lacking treatments that work.
- Conditions
- Chronic Interstitial Cystitis, Bladder Pain Syndrome, Painful Bladder Syndrome, Cystitis, Interstitial
- Trial name
- NCT06299683
- Testing
- Psychosocial Treatment, Pelvic Floor Physical Therapy
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- Vanderbilt University Medical Center
Interstitial Cystitis
Safety Study of LiRIS in Interstitial Cystitis (IC) Patients
The purpose of this study is primarily to evaluate the safety and tolerability of two dose levels of an investigational drug-delivery system (LiRIS) in patients who have moderate to severe symptoms of interstitial cystitis.
- Trial name
- NCT01150565
- Testing
- LiRIS low dose and LiRIS high dose
- Where
- 3 sites in Canada
- Volunteers
- 18 people
- Sponsor
- Allergan