Clinical trials: Interstitial Cystitis and Bladder Pain Syndrome
Interstitial Cystitis, Bladder Pain Syndrome
What is the Optimal Technique for Hydrodistention?
This research study is being done to learn what is the best way to perform hydrodistention. Eligible participants will be enrolled and have follow-up for three months after surgery.
- Trial name
- NCT05456308
- Testing
- Hydrodistention during cystoscope
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- University of Michigan
Overactive Bladder, Urinary Urge Incontinence
Reduction of Bladder Injection Pain With Belladonna Opiate Suppository
The purpose of this study is to test whether using belladonna \& opiate suppositories (B\&Os) can improve patient discomfort during Onabotulinumtoxin A (BoNT) injection into the bladder for treatment of overactive bladder…
- Conditions
- Overactive Bladder, Urinary Urge Incontinence, Urinary Bladder, Neurogenic, Painful Bladder Syndrome
- Trial name
- ROBIN (NCT02600715)
- Testing
- Onabotulinumtoxin A (BoNT), belladonna, Morphine
- Where
- 2 sites in United States
- Volunteers
- 26 people
- Sponsor
- Edgar LeClaire, MD
Interstitial Cystitis, Chronic Interstitial Cystitis
Investigation of PEMF Therapy for Female Patients With IC/BPS
The purpose of this study is to gather information about the safety and effectiveness of the non-pharmacological (non-drug), non-invasive treatment known as low-frequency pulsed electromagnetic field (PEMF) therapy.
- Conditions
- Interstitial Cystitis, Chronic Interstitial Cystitis, Bladder Pain Syndrome
- Trial name
- NCT05149573
- Testing
- Pulsed Electromagnetic Field (PEMF) Device
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Wake Forest University Health Sciences
Bladder Pain Syndrome, Interstitial Cystitis
A Study to Investigate Efficacy, Safety, Pharmacodynamics and Pharmacokinetics of ASP6294 in the Treatment of Female Subjects With Bladder Pain Syndrome/Interstitial Cystitis
The purpose of this study is to investigate efficacy, safety and tolerability of ASP6294 in female participants with Bladder Pain Syndrome/Interstitial Cystitis (BPS/IC).
- Trial name
- SERENITY (NCT03282318)
- Testing
- ASP6294
- Where
- 28 sites in Belgium, Czechia and 8 more
- Volunteers
- 119 people
- Sponsor
- Astellas Pharma Europe B.V.
Bladder Pain Syndrome
Comparative Study Suburothelial and Trigonal Botulinum Toxin A Injection in Treatment of Interstitial Cystitis
There is no consensus of the therapeutic efficacy and safety between suburothelial injection and trigonal injection of botulinum toxin A (BoNT-A) in treatment of interstitial cystitis/bladder pain syndrome (IC/BPS) It is unmet to…
- Trial name
- NCT03076762
- Testing
- intravesical onabotulinumtoxinA injection
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Buddhist Tzu Chi General Hospital
Interstitial Cystitis, Bladder Pain Syndrome
Intradetrusor Triamcinolone Injection in the Management of Interstitial Cystitis/Bladder Pain Syndrome
This initial pilot project aims to study the use of FDA-approved 40mg triamcinolone injections in the bladder for the management of interstitial cystitis with or without Hunner's lesions.
- Trial name
- NCT05226832
- Testing
- 40mg Triamcinolone Injections in the Bladder
- Sponsor
- The University of Texas Medical Branch, Galveston
Interstitial Cystitis, Bladder Pain Syndrome
Transvaginal Botulinum Toxin A for Interstitial Cystitis / Bladder Pain Syndrome
Interstitial cystitis / bladder pain syndrome (IC/BPS) is a debilitating condition that affects millions of women in the United States.
- Trial name
- T3STOPBPS (NCT05485207)
- Testing
- Transvaginal botulinum toxin A (BTA) injection
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Stanford University
Interstitial Cystitis
Urinary Biomarkers Characteristic to Interstitial Cystitis
This is a retrospective study of urine samples stored in the Beaumont BioBank for future research. The urine samples will be drawn from the urine back with patients previously diagnosed with severe interstitial cystitis (IC)…
- Trial name
- NCT00971568
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Corewell Health East
Bladder Pain Syndrome
The Safety and Efficacy of Gefapixant (AF-219/MK-7264) in Female Participants With Interstitial Cystitis /Bladder Pain Syndrome (MK-7264-005)
The purpose of this study is to assess the efficacy of gefapixant (AF-219/MK-7264) in female participants with moderate to severe pain associated with interstitial cystitis/bladder pain syndrome (IC/BPS) after 4 weeks of…
- Trial name
- NCT01569438
- Testing
- Gefapixant
- Where
- 41 sites in United States
- Volunteers
- 107 people
- Sponsor
- Afferent Pharmaceuticals, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Interstitial Cystitis, Painful Bladder Syndrome
Physical Therapy Trial for Pelvic Pain
The purpose of this study is to determine if a randomized trial of physical therapy for pelvic pain is feasible.
- Conditions
- Interstitial Cystitis, Painful Bladder Syndrome, Chronic Prostatitis, Chronic Pelvic Pain Syndrome
- Trial name
- UPPCRN-RCT#1 (NCT00434343)
- Testing
- Global Therapeutic Massage (GTM), Myofascial physical therapy (MPT)
- Where
- 5 sites in United States
- Volunteers
- 47 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Interstitial Cystitis, Painful Bladder Syndrome
IC PaIN Trial: Interstitial Cystitis Pain Improvement With Naltrexone
Interstitial cystitis/painful bladder syndrome (IC/PBS) is a debilitating condition with symptoms of urinary urgency, frequency, nocturia (waking up at night to void), and pain, without evidence of urinary tract infection or…
- Conditions
- Interstitial Cystitis, Painful Bladder Syndrome, Bladder Pain Syndrome, Low Dose Naltrexone
- Trial name
- NCT04313972
- Testing
- low-dose naltrexone
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Interstitial Cystitis, Bladder Pain Syndrome
Biopsychosocial and Conventional Approach in Bladder Pain Syndrome
The aim of the present study is to compare the effects of biopsychosocial and conventional approach on symptom severity, pain parameters (pain intensity and pain cognitions), disability, psychological distress and quality of life…
- Trial name
- NCT05155384
- Testing
- Pain Neuroscience Education, Relaxation exercises, Cognition target exercise
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Hacettepe University
IC, Hunner Type Interstitial Cystitis
The Study is Being Conducted to Find a New Treatment for Patients Suffering From Interstitial Cystitis With Hunner's Lesions
To evaluate the efficacy and safety of Neovasculgen in interstitial cystitis with Hunner's lesions to reduce cicatricial changes in the bladder caused by electrocoagulation and to prevent secondary bladder shrinkage with a…
- Conditions
- IC, Hunner Type Interstitial Cystitis, Bladder Pain Syndrome
- Trial name
- NCT07459790
- Testing
- Neovasculgen®
- Where
- Russia
- Volunteers
- 180 people
- Sponsor
- JSC NextGen
Bladder Pain Syndrome, Interstitial Cystitis
Hypnosis for Bladder Pain Syndrome
This is a pilot randomized control trial of 30 women with interstitial cystitis/bladder pain syndrome to determine the feasibility of delivering a hypnosis intervention or usual care on bladder pain (primary outcome) and cerebral…
- Trial name
- NCT04010513
- Testing
- Hypnosis, Standard of Care
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Pennsylvania
Interstitial Cystitis
Platelet-Rich Plasma (PRP) Injection in Treatment of Interstitial Cystitis
Interstitial cystitis/painful bladder syndrome (IC/PBS) is a debilitating chronic disease of unknown etiology characterized by urgency frequency and suprapubic pain at full bladder.
- Trial name
- NCT03104361
- Testing
- Platelet-Rich Plasma
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Buddhist Tzu Chi General Hospital
Interstitial Cystitis, Chronic Interstitial Cystitis
Efficacy of Pulsed Electromagnetic Field and Heparin/Bupivacaine Instillations
The objective of this study is to test the idea that Pulsed Electromagnetic Field (PEMF) therapy will serve as a safe therapeutic modality that can effectively be administered simultaneously with bladder instillations of a…
- Conditions
- Interstitial Cystitis, Chronic Interstitial Cystitis, Bladder Pain Syndrome
- Trial name
- NCT06013449
- Testing
- Pulsed Electromagnetic Field (PEMF) Device
- Sponsor
- Wake Forest University Health Sciences
Interstitial Cystitis
Safety Study of Single Intravesical Doses of TTI-1612 in Women With Interstitial Cystitis/Bladder Pain Syndrome
The purpose of this study is to determine the safety and pharmacokinetics of TTI-1612 in women with interstitial cystitis/bladder pain syndrome.
- Trial name
- NCT01559961
- Testing
- TTI-1612
- Where
- 4 sites in Canada
- Volunteers
- 28 people
- Sponsor
- Trillium Therapeutics Inc.
Chronic Prostatitis (CP), Chronic Pelvic Pain Syndrome (CPPS)
Genetic Study of Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)
Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS) is a condition with several causes of which some remain unknown. It is believed that some types of CP may be genetic or passed down (inherited) from one generation to the…
- Conditions
- Chronic Prostatitis (CP), Chronic Pelvic Pain Syndrome (CPPS), Painful Bladder Syndrome (PBS), Benign Frequency Syndrome (BFS)
- Trial name
- CP/CPPS (NCT00499317)
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Boston Children's Hospital
Cystitis, Interstitial
Treatment of Interstitial Cystitis/Painful Bladder Syndrome Using Alternative Techniques: Exercise, Meditation, Tai Chi
Complementary and alternative medicine (CAM) is the term for medical products and/or practices that are not part of the current standard of care.
- Trial name
- NCT00661050
- Testing
- Alternative Medicine, Tai Chi instruction and class participation or walking exercise and sitting meditation
- Where
- United States
- Sponsor
- Stanford University
Interstitial Cystitis, Bladder Diseases
Analysis of Expression of Nitric Oxide Syntheses and Their Functional Role in Human Urothelium
Painful bladder syndrome (PBS)/interstitial cystitis (IC) may be due to the actions of nitric oxide (NO) in the bladder tissue. NO is a gaseous substance with a very short half-life, synthesized by a group of NO-synthase-enzymes…
- Conditions
- Interstitial Cystitis, Bladder Diseases, Urinary Incontinence
- Trial name
- NCT00253006
- Testing
- Tissue examination for protein- and mRNA-expression of NO
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Copenhagen University Hospital at Herlev