Clinical trials: Intervention Effectiveness
Breast Neoplasm, Pain
Effectiveness of a Modern Educational Intervention in Breast Cancer Patients
In addition to fatigue, pain is the most frequent and persistent symptom following breast cancer and breast cancer treatment. Despite the effectiveness of different physical therapy modalities, such as manual techniques, passive…
- Trial name
- EduCan (NCT03351075)
- Testing
- Standard physical therapy program, Modern educational program, Traditional biomedical educational program
- Where
- Belgium
- Volunteers
- 184 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Asthma, Chronic Obstructive Pulmonary Disease (COPD)
Effectiveness of Interventions to Teach Respiratory Inhaler Technique (E-TRaIN)
The purpose of this study is to evaluate the relative effectiveness of two different ways to teach subjects while hospitalized how to use respiratory inhalers and to follow-up after discharge home from the hospital to determine…
- Trial name
- E-TRaIN (NCT01426581)
- Testing
- Teach-To-Goal, Brief Intervention
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Chicago
Infection Control, Preventive Measures
Effectiveness of a Online Training Program With a Clinical Procedure Standardized in Units of Nursing (CPSUN)
This study evaluates if the implementation of an online platform with procedures and protocols, improve the knowledge of professionals and can have a health impact related to decreased contamination of blood cultures.
- Trial name
- CPSUN (NCT02965989)
- Testing
- Online training of a nursing technique
- Where
- Spain
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Ignacio Zaragoza García
Tinnitus
CBT-based Internet Intervention for Adults With Tinnitus in the United States
Nearly 50 million people in the U.S. experience tinnitus, of which about 20 million people have burdensome chronic tinnitus. Tinnitus can be very debilitating as many aspects of daily life can be affected, such as sleep, mood…
- Trial name
- NCT04004260
- Testing
- Internet-based Cognitive Behavior Therapy
- Where
- United States
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- Lamar University
Childhood Obesity
Motivational Interviewing for Weight Loss
The investigators studied the effect of motivational interviewing (MI) on self-efficacy, health behaviors, and health outcomes in overweight children and adolescents (ages ranging from 10 to 18 years).
- Trial name
- NCT01246349
- Testing
- Motivational Interviewing (Treatment Group), Social Skills Training (Control Group)
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- The Hospital for Sick Children
Congenital Hemangioma, Hemangioendothelioma
A Study to Evaluate How Safe and Effective is the Mixture of Lipiodol® Ultra Fluid and Glue When Used for Embolization Procedures
This was a multicenter phase IV Post-Marketing Study. The study is designed to investigate the safety of Lipiodol® Ultra Fluid in association with surgical glues used according to each site medical practice of vascular…
- Conditions
- Congenital Hemangioma, Hemangioendothelioma, Angiosarcoma, Arteriovenous Malformations
- Trial name
- NCT02625389
- Testing
- Lipiodol Ultra Fluid with surgical glues
- Where
- 16 sites in India
- Volunteers
- 132 people
- Sponsor
- Guerbet
Multiple System Atrophy
A Study of Lu AF82422 in Participants With Multiple System Atrophy
To find out the effect of Lu AF82422 on disease progression in participants with multiple system atrophy.
- Trial name
- AMULET (NCT05104476)
- Testing
- Lu AF82422
- Where
- 19 sites in United States, Japan
- Volunteers
- 64 people
- Sponsor
- H. Lundbeck A/S
Spinal Disorders
An Interventional Study to Assess the Efficacy and Safety of Oxycodone/Naloxone in Korean Patients With Spinal Disorders
Study Objectives: 1. Primary objective To assess the pain reduction after 8 weeks treatment from baseline (week 0) 2. Secondary objectives To assess the pain reduction after 4 weeks treatment from baseline (week 0) To assess the…
- Trial name
- TALENT (NCT01811238)
- Testing
- Oxycodone/naloxone
- Volunteers
- 240 people
- Sponsor
- Mundipharma Korea Ltd
Contraception, Knowledge, Attitudes, Practice
Testing the Impact of Two Posters on Contraceptive Knowledge, Contraceptive Preferences, and Perceived Pregnancy Risk
This study tests two posters that teach people about contraception: one designed by the Centers for Disease Control (CDC), and one designed by the researchers.
- Trial name
- NCT03372369
- Testing
- View CDC Poster, View Patient-Centered Poster
- Where
- United States
- Volunteers
- 990 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Posttraumatic Stress Disorder, Alcohol Use
CBT Texts for PTSD & Hazardous Drinking (Project Better)
The research study seeks to refine and test a brief, self-directed, intervention for individuals from the general public with PTSD and co-occurring HD that can be delivered via text-messaging.
- Trial name
- NCT05372042
- Testing
- CBT Text Messages
- Where
- United States
- Volunteers
- 505 people
- Sponsor
- University of Washington
Underage Drinking
Efficacy of a Web-Based Alcohol Intervention for High School Students
This study evaluates the efficacy of the eCHECKUP TO GO as an intervention to reduce underage drinking and the associated negative consequences among high school seniors.
- Trial name
- NCT03613818
- Testing
- eCHECKUP TO GO
- Where
- United States
- Volunteers
- 311 people, healthy volunteers welcome
- Sponsor
- Boise State University
Urological System Complication of Procedure, Urinary Tract Infections
Effectiveness of Single Dose Fosfomycin and Single Dose Levofloxacin as Pre-urodynamic Antibiotic for UTI Prevention
The goal of this clinical trial is to compare the use of single dose fosfomycin and single dose levofloxacin as pre-urodynamic antibiotic prophylaxis for urinary tract infection prevention post-urodynamic in patients with lower…
- Trial name
- NCT06017479
- Testing
- Fosfomycin 3000 MG, Levofloxacin 500mg
- Where
- Indonesia
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Atrial Fibrillation
EdoxabaN or Warfarin Therapy In Device Procedures in Patients With Non-Valvular Atrial Fibrillation
This is a prospective randomized comparative evaluation of Edoxaban and Warfarin for safety and efficacy in perioperative use in patients with non-valvular atrial fibrillation (AF) undergoing clinically indicated implantation or…
- Trial name
- ENTICED-AF (NCT02561897)
- Testing
- Edoxaban, Warfarin
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Electrophysiology Research Foundation
Bacteremia
A Cluster-randomized Cross-over Trial Evaluating the Comparative Effectiveness of Three Skin Antiseptic Interventions
Background: Contaminated blood cultures result in unnecessary antibiotic use, increased length of stay, and additional laboratory tests, all of which increase healthcare costs.
- Trial name
- NCT01216761
- Testing
- Iodine tincture, Chlorhexidine gluconate, Povidone iodine
- Volunteers
- 3,879 people
- Sponsor
- University of Michigan
Fever, Sepsis
AION BIOSYSTEMS, INC. Tempshield for Continuous Tempreature Monitoring
The purpose of this research study is to evaluate the effectiveness of the AION BIOSYTEMS, INC. tempshield ("Shield") temperature monitoring device and platform in detecting body temperature for children 2-4 years old.
- Trial name
- NCT07145541
- Testing
- Aion Tempshield Device
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- AION Biosystems
Diabetes
Multi-arm Intervention Diabetes Adherence Study
The purpose of this study is to compare the effectiveness of two different interventions to improve adherence to diabetes medications among patients with diabetes and poor metabolic control.
- Trial name
- MIDAS (NCT00754741)
- Testing
- Adherence information, Adherence information plus motivational interviewing
- Where
- United States
- Volunteers
- 1,692 people
- Sponsor
- Henry Ford Health System
Anemia
Study to Evaluate the Efficacy & Safety of the INTERCEPT Blood System for RBCs in Complex Cardiac Surgery Patients
The objective of this study is to evaluate the efficacy and safety of RBC transfusion for support of acute anemia in cardiovascular surgery patients based on the clinical outcome of renal impairment following transfusion of red…
- Trial name
- ReCePI (NCT03459287)
- Testing
- INTERCEPT, Control
- Where
- 18 sites in United States
- Volunteers
- 581 people
- Sponsor
- Cerus Corporation
Migraine
A Study to Evaluate the Efficacy and Safety of Eptinezumab for the Prevention of Migraine in Participants That Are Not Helped by Previous Preventive Treatments
Evaluation of eptinezumab in the prevention of migraine in participants with unsuccessful prior preventive treatments.
- Trial name
- DELIVER (NCT04418765)
- Testing
- Eptinezumab
- Where
- 138 sites in United States, Belgium and 15 more
- Volunteers
- 892 people
- Sponsor
- H. Lundbeck A/S
Alcohol Drinking, Alcohol Intoxication
Mindfulness-Based Intervention and Transcranial Direct Current Brain Stimulation to Reduce Heavy Drinking
Alcohol use disorder (AUD) impacts millions of Americans and is associated with significant behavioral, social, economic, medical, and neurobiological dysfunction, yet current behavioral treatments for AUD are only modestly…
- Conditions
- Alcohol Drinking, Alcohol Intoxication, Alcoholism
- Trial name
- MBItDCS (NCT02861807)
- Testing
- Brain stimulation with mindfulness-based relapse prevention
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- University of New Mexico
HIV Infections, Smoking
Improving the Reach & Effectiveness of Smoking Cessation Services Targeted to Veterans Living With HIV
This project will compare the effectiveness of an HIV-specific comprehensive wellness intervention designed to have broad appeal to smokers living with HIV to the effectiveness of standard care services that include referral to…
- Conditions
- HIV Infections, Smoking, Smoking Cessation
- Trial name
- WISH (NCT04505371)
- Testing
- Wellness Intervention for Smokers with HIV
- Where
- United States
- Volunteers
- 235 people, healthy volunteers welcome
- Sponsor
- Seattle Institute for Biomedical and Clinical Research