Clinical trials: Intervention Effectiveness
NMOSD, Neuromyelitis Optica Spectrum Disorders
Efficacy, Safety, PK, PD, and ADA of Eculizumab in Chinese Adults With NMOSD
The primary objective of this study is to evaluate the efficacy, safety, pharmacokinetics, pharmacodynamics, and immunogenicity of Eculizumab in Chinese Adults with Neuromyelitis Optica Spectrum Disorders (NMOSD).
- Trial name
- ECU-NMO-304 (NCT06724809)
- Testing
- eculizumab
- Where
- 7 sites in China
- Volunteers
- 21 people
- Sponsor
- Alexion Pharmaceuticals, Inc.
Glioblastomas, Sarcoma
Feasibility and Preliminary Efficacy of a Mindfulness-based Intervention for Children and Young Adults With High Grade or High-Risk Cancer and Their Caregivers
Background: People cope with cancer in different ways. Mindfulness means focusing on the present moment with an open mind. Researchers want to see if this can help children and young adults with a high-grade high-risk cancer with…
- Conditions
- Glioblastomas, Sarcoma, Astrocytoma, Brain Cancer
- Trial name
- NCT03538587
- Testing
- Enhanced Mindfulness Intervention, Psychoeducation
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Birth Defects
Effectiveness of Comprehensive Tertiary Interventions on Incidence and Clinical Outcomes of Birth Defects
This project is a single blind cluster randomized controlled trial with a purpose of assessing the effectiveness of a comprehensive tertiary interventions (before pregnancy, during pregnancy and after delivery) on the incidence…
- Trial name
- NCT03725878
- Testing
- Standard tertiary interventions of birth defects, Additional preconception health care, Additional health care procedures during and after pregnancy
- Where
- China
- Volunteers
- 4,808 people
- Sponsor
- Children's Hospital of Fudan University
Coronary Artery Disease
The Efficacy and Safty of Proton Pump Inhibitor (Lansoprazole)
Among patients who performed percutaneous coronary intervention (PCI) in patients with coronary artery disease (CAD), enrollment is performed in patients with moderate risk in gastrointestinal risk assessment indicators.
- Trial name
- PPI (NCT05820048)
- Testing
- Lansoprazole 15 mg
- Volunteers
- 300 people
- Sponsor
- Daejeon St. Mary's hospital
Breast Cancer, Lung Cancer
Implementation, Effectiveness and Impact of a Value Based Intervention for Patients with Breast or Lung Cancer
VOICE project aims to guide health services in their reorganization towards the provision of the highest value care for the patient at the best cost. VOICE is targeted to patients with breast and lung cancer.
- Trial name
- VOICE (NCT04960735)
- Testing
- VOICE intervention
- Where
- 8 sites in Belgium, France and 3 more
- Volunteers
- 1,007 people
- Sponsor
- Biosistemak Institute for Health Systems Research
Autism Spectrum Disorder, Autistic Disorder
Improving Hospitalizations for Children With ASD
This study aims to implement and test a specific brief Applied Behavior Analysis model for assessing and responding to severe challenging behavior during acute medical and behavioral hospitalization for children with ASD.
- Trial name
- NCT02339935
- Testing
- Brief Analogue Functional Analysis, No Brief AFA
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Vanderbilt University
Underage Drinking, Drinking, Teen
Examining an Intervention to Reduce High School Drinking
Underage drinking is a significant problem in the United States. While past research supports the efficacy of interventions in delaying the initiation of alcohol use implemented in middle school and early high school, research…
- Conditions
- Underage Drinking, Drinking, Teen, Adolescent Alcohol Use
- Trial name
- NCT07086508
- Testing
- e-CHECKUP TO GO (eCTG), e-Parent Intervention
- Where
- United States
- Volunteers
- 2,532 people, healthy volunteers welcome
- Sponsor
- Binghamton University
Breast Feeding
Happy, Healthy, Loved: A Mobile-delivered Breastfeeding Self-efficacy Intervention for First Time Parents
The purpose of this study is to test if a mobile device delivered intervention program can improve breast-feeding self-efficacy in primiparous mothers.
- Trial name
- HHL (NCT04578925)
- Testing
- Happy, Healthy, Loved
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- OhioHealth
Cancer, Psychooncology
E-intervention on Subclinical Fear of Cancer Recurrence
The present study aims to adapt a metacognition-based ConquerFear-HK to an internet-based self-management intervention, namely eConquerFear-HK and evaluate in a randomised controlled trial, its feasibility, utility, and potential…
- Conditions
- Cancer, Psychooncology, Fear of Cancer Recurrence
- Trial name
- NCT06207006
- Testing
- eConquerFear-HK, Basic Cancer Care
- Where
- Hong Kong
- Volunteers
- 49 people
- Sponsor
- The University of Hong Kong
Cardiovascular Diseases
Web-based Physical Activity Intervention to Promote Physical Activity
In this study insufficiently active adults with obesity will be assigned to either the Physical Activity for The Heart (PATH) intervention or an attention control group.
- Trial name
- NCT05803304
- Testing
- PATH Intervention, Attention Control Intervention, Physical activity tracker
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Emory University
Atrial Fibrillation, Rivaroxaban
Rivaroxaban in Elderly NVAF Patients With or Without Renal Impairment
Study Type and Design Prospective, Observational Study Rivaroxaban in Elderly AF patients with or without renal impairment in Korea This study will investigate effectiveness and safety in elderly patients, the result from…
- Conditions
- Atrial Fibrillation, Rivaroxaban, Elderly, Renal Insufficiency
- Trial name
- XAIENT (NCT04096547)
- Testing
- Rivaroxaban
- Where
- South Korea
- Volunteers
- 1,200 people
- Sponsor
- Samsung Medical Center
PTSD, Stress, Psychological
The Efficacy of a Physical Activity Counselling Intervention on Mental Health in Firefighters
Objectives: The aim of this project will be to evaluate the efficacy of a lifestyle PA counselling program for physically inactive first responders with at least mild symptoms of either anxiety, depression or stress and their…
- Conditions
- PTSD, Stress, Psychological, Depressive Symptoms, Anxiety Disorders and Symptoms
- Trial name
- NCT05061225
- Testing
- Physical activity counselling
- Volunteers
- 60 people
- Sponsor
- KU Leuven
Anxiety and Depression, Disorders of Gut-brain Interaction
Development of an Online ACT Intervention for Disorders of Gut-Brain Interaction
The goal of this clinical trial is to develop and test the iACTforDGBI intervention in a sample of Swedish individuals with DGBI (Disorders of Gut-Brain Interaction).
- Trial name
- iACTforDGBI (NCT06309004)
- Where
- Sweden
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Örebro University, Sweden
Mild Cognitive Impairment, Cognitive Impairment
Effectiveness of Cognitive Rehabilitation for Amnestic Mild Cognitive Impairment
Different cognitive rehabilitation intervention methods have been developed for the treatment of cognitive dysfunctions seen in mild cognitive impairment (MCI).
- Trial name
- NCT05664984
- Testing
- 1-face-to-face, 2-tele rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Saglik Bilimleri Universitesi
Heart Failure
Management of Patients With HF by Using Educational or Educational & Telephone or Telephone Interventions and Support in Cyprus
The current trial aims to examine the effectiveness of three different types of nursing interventions, on heart failure (HF) patients' quality of life and on HF outcomes, compared to the usual care.
- Trial name
- MEETTinCY (NCT01905176)
- Testing
- In person education on heart failure topics before discharge, Telephone support and education post-discharge, Pre-discharge in person education and post-discharge telephone education and support
- Where
- Cyprus
- Volunteers
- 300 people
- Sponsor
- Cyprus University of Technology
Cerebrovascular Accident, Musculoskeletal Equilibrium
Evaluation of an Intervention Program Targeted at Improving Balance and Functional Skills After Stroke
The purpose of this study is to evaluate a 5-week intervention program targeted at improving balance and functional skills for people with stroke.
- Trial name
- NCT00377689
- Testing
- high intensity functional exercise
- Where
- Sweden
- Volunteers
- 34 people
- Sponsor
- Umeå University
Skin Disease
Washing Without Water: Cost-effectiveness of a Rapidly Spreading Nursing Intervention in Bedridden Patients'
The purpose of this study is to compare the traditional bed bath with 'washing without water' on 1) effects on skin integrity 2) patient and nurse satisfaction and 3) costs.
- Trial name
- WWW (NCT01187732)
- Testing
- Washing without water
- Where
- Netherlands
- Volunteers
- 500 people
- Sponsor
- Betsie van Gaal
Chronic Total Occlusion of Coronary Artery
Safety and Efficacy Study of the SoundBite™ Crossing System With ACTIVE Wire in Coronary CTOs.
The objective of this study is to evaluate the safety and efficacy of the SoundBite™ Crossing System - Coronary (SCS-C) in a subject population with chronic coronary artery disease including Chronic Total Occlusion (CTO).
- Trial name
- ACTIVE (NCT03521804)
- Testing
- SoundBite™ Crossing System Active Wire 14
- Where
- 5 sites in United States, Canada
- Volunteers
- 35 people
- Sponsor
- SoundBite Medical Solutions, Inc.
Triple Negative Breast Cancer (TNBC), Early Setting
LifEStyle Intervention to Enhance Efficacy of Neoadjuvant Therapy in Patients With Triple Negative Breast Cancer
LESLIE is a multicentric randomized controlled trial in patients with triple negative breast cancer receiving neoadjuvant chemo/immunotherapy (NAT).
- Trial name
- LESLIE (NCT06831955)
- Testing
- Exercise Therapy, Fasting-Mimicking Diet, SOC
- Where
- 10 sites in Belgium
- Volunteers
- 356 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Fecal Incontinence
Comparing the Effectiveness of Two Dietary Interventions for Fecal Incontinence
Background: Fecal incontinence (FI) is a common complaint, and is often associated with diarrhea and urgency. Foods that are high in fermentable oligo-, di-, and mono-saccharides and polyols (FODMAPs) cause symptoms of diarrhea…
- Trial name
- NCT02828384
- Testing
- low fodmap diet, Psyllium
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Michigan
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.